List of works by David A. Cairns

89 Development and external validation of a multivariable model of pre-test likelihood of coronary artery disease based on a contemporary uk population, with comparison to existing risk models

scholarly article by James RJ Foley et al published June 2017 in Heart

A pilot study to investigate the potential of mass spectrometry profiling in the discovery of novel serum markers in chronic renal disease

scientific article

A systematic analysis of the effects of increasing degrees of serum immunodepletion in terms of depth of coverage and other key aspects in top-down and bottom-up proteomic analyses

scientific article (publication date: June 2011)

An analysis of the impact of pre-analytical factors on the urine proteome: Sample processing time, temperature, and proteolysis ⬇️

scientific article

Analysis of VHL Gene Alterations and their Relationship to Clinical Parameters in Sporadic Conventional Renal Cell Carcinoma

scientific article published on December 2009

Application of the random forest classification method to peaks detected from mass spectrometric proteomic profiles of cancer patients and controls

scientific article

Biomarkers and response to bevacizumab--response.

scientific article published in February 2014

CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment ⬇️

scientific article published on 12 January 2016

Cardiac resynchronization therapy outcomes in patients with chronic heart failure: cardiac resynchronization therapy with pacemaker versus cardiac resynchronization therapy with defibrillator

scientific article

Changes in the urinary proteome post-operatively in renal cancer patients - a reflection of tumour or kidney removal?

scientific article

Characterisation of immunoparesis in newly diagnosed myeloma and its impact on progression-free and overall survival in both old and recent myeloma trials ⬇️

scientific article published on 20 June 2018

Chronotropic Incompetence Does Not Limit Exercise Capacity in Chronic Heart Failure ⬇️

scientific article

Copy number evolution and its relationship with patient outcome-an analysis of 178 matched presentation-relapse tumor pairs from the Myeloma XI trial

scientific article published on 01 December 2020

Coronary microvascular dysfunction in patients with stable coronary artery disease: The CE-MARC 2 coronary physiology sub-study. ⬇️

scientific article published on 19 April 2018

Early relapse after high-dose melphalan autologous stem cell transplant predicts inferior survival and is associated with high disease burden and genetically high-risk disease in multiple myeloma

scientific article published on 10 June 2020

Effect of Care Guided by Cardiovascular Magnetic Resonance, Myocardial Perfusion Scintigraphy, or NICE Guidelines on Subsequent Unnecessary Angiography Rates: The CE-MARC 2 Randomized Clinical Trial ⬇️

scientific article published on 29 August 2016

Genetic factors influencing the risk of multiple myeloma bone disease ⬇️

scientific article

Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma ⬇️

scientific article published on 8 January 2016

High-dose chemotherapy plus autologous stem-cell transplantation as consolidation therapy in patients with relapsed multiple myeloma after previous autologous stem-cell transplantation (NCRI Myeloma X Relapse [Intensive trial]): a randomised, open-l

scientific article

Influences of blood sample processing on low-molecular-weight proteome identified by surface-enhanced laser desorption/ionization mass spectrometry

scientific article

Initial development and validation of a novel extraction method for quantitative mining of the formalin-fixed, paraffin-embedded tissue proteome for biomarker investigations

scientific article

Integrated multi-level quality control for proteomic profiling studies using mass spectrometry

scientific article

Maintenance Treatment and Survival in Patients With Myeloma: A Systematic Review and Network Meta-analysis

scientific article published on 01 October 2018

Methods for the evaluation of biomarkers in patients with kidney and liver diseases: multicentre research programme including ELUCIDATE RCT ⬇️

article

NuMA overexpression in epithelial ovarian cancer ⬇️

scientific article

Optimising the value of immunomodulatory drugs during induction and maintenance in transplant ineligible patients with newly diagnosed multiple myeloma: results from Myeloma XI, a multicentre, open-label, randomised, Phase III trial

scientific article published on 12 July 2020

Performance of 2014 NICE defibrillator implantation guidelines in heart failure risk stratification ⬇️

scientific article published on 8 February 2016

Predicting response to bevacizumab in ovarian cancer: a panel of potential biomarkers informing treatment selection

scientific article

Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients. ⬇️

scientific article published on 06 June 2017

Proteomic analysis of formalin-fixed paraffin-embedded renal tissue samples by label-free MS: assessment of overall technical variability and the impact of block age.

scientific article

Proteomic identification of differentially expressed plasma membrane proteins in renal cell carcinoma by stable isotope labelling of a von Hippel-Lindau transfectant cell line model

scientific article published on April 2009

Proteomic profiling using mass spectrometry--does normalising by total ion current potentially mask some biological differences?

scientific article

Quality of life during and following sequential treatment of previously untreated patients with multiple myeloma: findings of the Medical Research Council Myeloma IX randomised study ⬇️

scientific article published on 09 July 2018

Rate-Response Programming Tailored to the Force-Frequency Relationship Improves Exercise Tolerance in Chronic Heart Failure ⬇️

scientific article published on 27 November 2017

Retinoic acid-induced protein 3: identification and characterisation of a novel prognostic colon cancer biomarker

scientific article published on 26 September 2012

Sample size determination in clinical proteomic profiling experiments using mass spectrometry for class comparison

scientific article published in January 2009

Second Revision of the International Staging System (R2-ISS) for Overall Survival in Multiple Myeloma: A European Myeloma Network (EMN) Report Within the HARMONY Project

scientific article published in 2022

Serum aminoacylase-1 is a novel biomarker with potential prognostic utility for long-term outcome in patients with delayed graft function following renal transplantation

scientific article published on 05 June 2013

Serum biomarker discovery in renal cancer using 2-DE and prefractionation by immunodepletion and isoelectric focusing; increasing coverage or more of the same?

scientific article published on December 2008

Statistical issues in quality control of proteomic analyses: good experimental design and planning

scientific article published on 07 February 2011

Statistical issues in the design and planning of proteomic profiling experiments

scientific article published in January 2015

Stem Cell Harvesting after Bortezomib-Based Reinduction for Myeloma Relapsing after Autologous Transplantation: Results from the British Society of Blood and Marrow Transplantation/United Kingdom Myeloma Forum Myeloma X (Intensive) Trial. ⬇️

scientific article published on 28 January 2016

The effect of salvage autologous stem-cell transplantation on overall survival in patients with relapsed multiple myeloma (final results from BSBMT/UKMF Myeloma X Relapse [Intensive]): a randomised, open-label, phase 3 trial ⬇️

scientific article published on July 2016

The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation ⬇️

The impact of cytogenetics on duration of response and overall survival in patients with relapsed multiple myeloma (long-term follow-up results from BSBMT/UKMF Myeloma X Relapse [Intensive]): a randomised, open-label, phase 3 trial

scientific article published on 06 February 2019

The prognostic and predictive value of CA-125 regression during neoadjuvant chemotherapy for advanced ovarian or primary peritoneal carcinoma

scientific article

The relative importance of factors predicting outcome for myeloma patients at different ages: results from 3894 patients in the Myeloma XI trial

scientific article published on 14 October 2019

The role of ixazomib as an augmented conditioning therapy in salvage autologous stem cell transplant (ASCT) and as a post-ASCT consolidation and maintenance strategy in patients with relapsed multiple myeloma (ACCoRd [UK-MRA Myeloma XII] trial): stu ⬇️

scientific article published on 7 March 2018

Urinary biomarker profiling in transitional cell carcinoma.

scientific article published in December 2006

Using the protein chip interface with quadrupole time-of-flight mass spectrometry to directly identify peaks in SELDI profiles--initial evaluation using low molecular weight serum peaks

scientific article

miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth ⬇️

scientific article

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