List of works by Heather J Lee

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

scientific article published on 01 December 2019

Accurate prediction of single-cell DNA methylation states using deep learning

scholarly article published 27 May 2016

Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation.

scientific article published on May 2007

DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

scientific article

ELF5 isoform expression is tissue-specific and significantly altered in cancer.

scientific article

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

scientific article

Etoposide induces nuclear re-localisation of AID

scientific article

FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency

scientific article published on 11 July 2013

Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency

scientific article published on 01 July 2018

Genome-Wide Analysis of DNA Methylation in Single Cells Using a Post-bisulfite Adapter Tagging Approach.

scientific article published in January 2018

Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq).

scientific article

Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants.

scientific article published on 15 October 2009

Interplay between progesterone and prolactin in mammary development and implications for breast cancer.

scientific article published on 16 September 2011

Lineage specific methylation of the Elf5 promoter in mammary epithelial cells.

scientific article

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

scientific article

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

scientific article published on 11 January 2016

Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells.

scientific article published on 5 March 2013

Reprogramming the methylome: erasing memory and creating diversity

scientific article

Single-cell epigenomics in cancer: charting a course to clinical impact

scientific article published on 13 August 2020

Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity

scientific article published on 18 April 2016

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity

scientific article

Tracking the embryonic stem cell transition from ground state pluripotency

scientific article

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells

scientific article published on 22 February 2018

scTEM-seq: Single-cell analysis of transposable element methylation to link global epigenetic heterogeneity with transcriptional programs

scientific article published on 06 April 2022

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