List of works - William G Fairbrother

A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress

scientific article (publication date: 15 January 2009)

A rapid high-throughput method for mapping ribonucleoproteins (RNPs) on human pre-mRNA.

scientific article

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

scientific article

Association between regulator of G protein signaling 9-2 and body weight

scientific article (publication date: 2011)

Combinatorial binding of transcription factors in the pluripotency control regions of the genome

scientific article

Defective splicing of the RB1 transcript is the dominant cause of retinoblastomas.

scientific article published on 5 August 2017

Genetic variation and RNA binding proteins: tools and techniques to detect functional polymorphisms

scientific article published on January 2014

Hereditary cancer genes are highly susceptible to splicing mutations.

scientific article published on 5 March 2018

High-throughput binding analysis determines the binding specificity of ASF/SF2 on alternatively spliced human pre-mRNAs

scientific article

High-throughput biochemical analysis of in vivo location data reveals novel distinct classes of POU5F1(Oct4)/DNA complexes

scientific article

High-throughput mapping of protein occupancy identifies functional elements without the restriction of a candidate factor approach ⬇️

scientific article published on December 17, 2010

ISWI contributes to ArsI insulator function in development of the sea urchin

scientific article

Large-scale analysis of branchpoint usage across species and cell lines

scientific article published on 24 January 2017

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

scientific article

Linking C5 deficiency to an exonic splicing enhancer mutation

scientific article

Linking C5 deficiency to an exonic splicing enhancer mutation

Messenger RNA Splicing Signals

Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence

scientific article

Pathogenic variants that alter protein code often disrupt splicing.

scientific article published on 17 April 2017

Predictive identification of exonic splicing enhancers in human genes

scientific article (publication date: 9 August 2002)

RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons

scientific article

RNA structure in splicing: An evolutionary perspective

scientific article published on 25 July 2016

RNA structure replaces the need for U2AF2 in splicing

scientific article

RNA-Binding Proteins: Splicing Factors and Disease

scientific article

Recessive truncating titin gene, TTN, mutations presenting as centronuclear myopathy

scientific article published on 23 August 2013

Repressing the neuron within

scientific article published on January 2008

Single nucleotide polymorphism-based validation of exonic splicing enhancers

scientific article published in September 2004

Soluble programmed cell death receptor-1 (sPD-1): a potential biomarker with anti-inflammatory properties in human and experimental acute respiratory distress syndrome (ARDS).

scientific article

Spliceman--a computational web server that predicts sequence variations in pre-mRNA splicing

scientific article

Spliceman2: a computational web server that predicts defects in pre-mRNA splicing

scientific article published in September 2017

Tetracarbonylmolybdenum complexes of 2-(phenylazo)pyridine ligands. Correlations of molybdenum-95 chemical shifts with electronic, infrared, and electrochemical properties

The effects of structure on pre-mRNA processing and stability

scientific article

The importance of p53 pathway genetics in inherited and somatic cancer genomes.

scientific article published on March 2016

Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes

scientific article

Widespread intra-dependencies in the removal of introns from human transcripts

scientific article published in September 2017

List of works by William G Fairbrother

A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress

A rapid high-throughput method for mapping ribonucleoproteins (RNPs) on human pre-mRNA.

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Association between regulator of G protein signaling 9-2 and body weight

Combinatorial binding of transcription factors in the pluripotency control regions of the genome

Defective splicing of the RB1 transcript is the dominant cause of retinoblastomas.

Genetic variation and RNA binding proteins: tools and techniques to detect functional polymorphisms

Hereditary cancer genes are highly susceptible to splicing mutations.

High-throughput binding analysis determines the binding specificity of ASF/SF2 on alternatively spliced human pre-mRNAs

High-throughput biochemical analysis of in vivo location data reveals novel distinct classes of POU5F1(Oct4)/DNA complexes

High-throughput mapping of protein occupancy identifies functional elements without the restriction of a candidate factor approach ⬇️

ISWI contributes to ArsI insulator function in development of the sea urchin

Large-scale analysis of branchpoint usage across species and cell lines

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo

Linking C5 deficiency to an exonic splicing enhancer mutation

Linking C5 deficiency to an exonic splicing enhancer mutation

Messenger RNA Splicing Signals

Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence

Pathogenic variants that alter protein code often disrupt splicing.

Predictive identification of exonic splicing enhancers in human genes

RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons

RNA structure in splicing: An evolutionary perspective

RNA structure replaces the need for U2AF2 in splicing

RNA-Binding Proteins: Splicing Factors and Disease

Recessive truncating titin gene, TTN, mutations presenting as centronuclear myopathy

Repressing the neuron within

Single nucleotide polymorphism-based validation of exonic splicing enhancers

Soluble programmed cell death receptor-1 (sPD-1): a potential biomarker with anti-inflammatory properties in human and experimental acute respiratory distress syndrome (ARDS).

Spliceman--a computational web server that predicts sequence variations in pre-mRNA splicing

Spliceman2: a computational web server that predicts defects in pre-mRNA splicing

Tetracarbonylmolybdenum complexes of 2-(phenylazo)pyridine ligands. Correlations of molybdenum-95 chemical shifts with electronic, infrared, and electrochemical properties

The effects of structure on pre-mRNA processing and stability

The importance of p53 pathway genetics in inherited and somatic cancer genomes.

Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes

Widespread intra-dependencies in the removal of introns from human transcripts