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List of works by Luis B Barreiro

A Short-Term High-Fat Diet Alters Glutathione Levels and IL-6 Gene Expression in Oxidative Skeletal Muscles of Young Rats

article

A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection

scientific article

Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers.

scientific article

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.

scientific article

Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region

scientific article published on 14 February 2013

Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection

scientific article published on 06 September 2016

Annexin1 regulates DC efferocytosis and cross-presentation during Mycobacterium tuberculosis infection.

scientific article

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis

scientific article published in January 2018

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

scientific article

Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution

scientific article published on 3 September 2015

Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease

scientific article published on 07 February 2019

Common methods for fecal sample storage in field studies yield consistent signatures of individual identity in microbiome sequencing data

scientific article

DC-SIGN interacts with Mycobacterium leprae but sequence variation in this lectin is not associated with leprosy in the Pakistani population

scientific article published in January 2006

DC‐SIGNRNeck‐Region Polymorphisms and HIV‐1 Susceptibility: From Population Stratification to a Possible Advantage of the 7/5 Heterozygous Genotype

article

Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes

scientific article

Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection

scientific article published on 10 January 2012

Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation.

scientific article published on 9 August 2017

Defining trained immunity and its role in health and disease

scientific article published on 04 March 2020

Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations

scientific article

Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America

scientific article

Dominance rank causally affects personality and glucocorticoid regulation in female rhesus macaques

scientific article

Don't move: LRRK2 arrests NFAT in the cytoplasm

scientific article published on 19 October 2011

Editorial Overview: Immunogenetics and transplantation: Bringing evolution and genomics to human immunology

scholarly article by Luis B Barreiro & Lluís Quintana-Murci published October 2014 in Current Opinion in Immunology

Evolution of the TIR domain-containing adaptors in humans: swinging between constraint and adaptation

scientific article published on 9 June 2011

Evolutionary and population (epi)genetics of immunity to infection

scientific article published on 13 April 2020

Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense

scientific article

Evolutionary genetic dissection of human interferons

scientific article published on 12 December 2011

Evolutionary genetics evidence of an essential, nonredundant role of the IFN-γ pathway in protective immunity

scientific article published on 29 March 2011

Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles

scientific article published on 2 August 2006

Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets

scientific article

Extracellular Adenosine Triphosphate Affects the Response of Human Macrophages Infected With Mycobacterium tuberculosis

article

Fetal microglial phenotype in vitro carries memory of prior in vivo exposure to inflammation

scientific article published on 4 August 2015

Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions

scientific article

From evolutionary genetics to human immunology: how selection shapes host defence genes

scientific article published on December 2009

Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family

scientific article

Functional comparison of innate immune signaling pathways in primates

scientific article

Gene activation precedes DNA demethylation in response to infection in human dendritic cells

article

Gene set signature of reversal reaction type I in leprosy patients

scientific article

Gene-body 5-hydroxymethylation is associated with gene expression changes in the prefrontal cortex of depressed individuals

scientific article published on 09 May 2017

Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens

scientific article

Genetic ancestry effects on the response to viral infection are pervasive but cell type specific

scientific article published on 25 November 2021

Genetic and evolutionary determinants of human population variation in immune responses

scientific article published on 28 June 2018

Genetic and transcriptional analysis of human host response to healthy gut microbiota.

scientific article published on July 2016

Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.

scientific article

Genome-Wide Association Studies of the Human Gut Microbiota

scientific article published on 3 November 2015

Genome-wide quantification of the effects of DNA methylation on human gene regulation

article

Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest

scientific article published on 08 August 2019

Getting under—and through—the skin: ecological genomics of chytridiomycosis infection in frogs.

scientific article

High-throughput SNP genotyping: combining tag SNPs and molecular beacons.

scientific article

Holy Immune Tolerance, Batman!

scientific article published on 01 June 2018

Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12.

scientific article

Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set

scientific article published in April 2009

Integration of genetic and immunological insights into a model of celiac disease pathogenesis

scientific article

Lack of association between genetic polymorphisms in enzymes associated with folate metabolism and unexplained reduced sperm counts.

scientific article

Length Variation of DC-SIGN and L-SIGN Neck-Region has no Impact on Tuberculosis Susceptibility

scientific article published on 04 December 2006

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

scientific article

Mycobacterial infection induces a specific human innate immune response

scientific article

Natural selection contributed to immunological differences between hunter-gatherers and agriculturalists

scientific article published on 29 July 2019

Natural selection has driven population differentiation in modern humans

scientific article

Polygenic adaptation and convergent evolution on growth and cardiac genetic pathways in African and Asian rainforest hunter-gatherers

article published in the Proceedings of the National Academy of Sciences of the United States of America

Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells

scientific article

Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients

scientific article

Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis

scientific article

Protective role of DC-SIGN (CD209) neck-region alleles with <5 repeat units in HIV-1 transmission.

scientific article published in July 2008

Proteomic characterization of phagosomal membrane microdomains during phagolysosome biogenesis and evolution

scientific article (publication date: November 2012)

Quantitative trait loci (QTL) study identifies novel genomic regions associated to Chiari-like malformation in Griffon Bruxellois dogs

scientific article

RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain.

scientific article

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.

scientific article published on April 2017

Reservoir host immune responses to emerging zoonotic viruses

scientific article

Seasonal variation in human gut microbiome composition

scientific article

Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages

scientific article published on 9 October 2006

Signatures of purifying and local positive selection in human miRNAs

scientific article published on 19 February 2009

Social affiliation predicts mitochondrial DNA copy number in female rhesus macaques

scientific article published on 01 January 2019

Social environment is associated with gene regulatory variation in the rhesus macaque immune system

scientific article published on 9 April 2012

Social networks predict gut microbiome composition in wild baboons.

scientific article

Social status alters chromatin accessibility and the gene regulatory response to glucocorticoid stimulation in rhesus macaques

article published in the Proceedings of the National Academy of Sciences of the United States of America

Social status alters immune regulation and response to infection in macaques.

scientific article

Social status drives social relationships in groups of unrelated female rhesus macaques

scientific article published in January 2016

Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity

scientific article published in 2024

Synchrony and idiosyncrasy in the gut microbiome of wild baboons

scientific article published in June 2022

TLR3 deficiency in patients with herpes simplex encephalitis

scientific article

The contribution of admixture to primate evolution

scientific article published on 15 September 2017

The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease

scientific article

The demographic history and mutational load of African hunter-gatherers and farmers

scientific article published on 12 March 2018

The epigenomic landscape of African rainforest hunter-gatherers and farmers

scientific article

The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region

scientific article

The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists

scientific article published in January 2014

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation

scientific article published on 21 March 2016

The role played by natural selection on Mendelian traits in humans

scientific article published on December 1, 2010

Trained immunity, tolerance, priming and differentiation: distinct immunological processes

scientific article published on 08 December 2020

Vaginal microbiome in early pregnancy and subsequent risk of spontaneous preterm birth: a case-control study

scientific article published on 27 June 2018

When genetics meets epigenetics: deciphering the mechanisms controlling inter-individual variation in immune responses to infection

scientific article published on 28 June 2014

Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection.

scientific article

bacterial infection drives the expression dynamics of microRNAs and their isomiRs

scientific article

pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates in Portugal.

scientific article

α7 nicotinic acetylcholine receptor signaling modulates the inflammatory phenotype of fetal brain microglia: first evidence of interference by iron homeostasis

scientific article published on 6 September 2017