Search filters

List of works by Jennifer McKimm-Breschkin

A clinical trial lacking a control group

scientific article published on 16 October 2019

A generic system for the expression and purification of soluble and stable influenza neuraminidase

scientific article published in 2011

A new method for the purification of the influenza A virus neuraminidase.

scientific article published in April 1991

A simplified plaque assay for respiratory syncytial virus--direct visualization of plaques without immunostaining

scientific article published on September 2004

Affinity ranking of influenza neuraminidase mutants with monoclonal antibodies using an optical biosensor. Comparison with ELISA and slot blot assays

scientific article published on 01 January 1994

Anti-oxazolone hybridomas and strain distribution of the oxazolone idiotype

scientific article published on 01 November 1983

Catalytic mechanism and novel receptor binding sites of human parainfluenza virus type 3 hemagglutinin-neuraminidase (hPIV3 HN)

scientific article

Changes in the NS gene of neurovirulent strains of influenza affect splicing.

scientific article published in January 1995

Characterisation of an avian influenza virus nucleoprotein expressed in E. coli and in insect cells.

scientific article published in January 1990

Complexity in influenza virus targeted drug design: interaction with human sialidases.

scientific article

Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use.

scientific article

Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.

scientific article

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase ⬇️

scientific article published on June 15, 1998

ER stress triggers apoptosis by activating BH3-only protein Bim

scientific article (publication date: 29 June 2007)

Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network.

scientific article

Expression of influenza neuraminidase in baculovirus-infected cells

scientific article published in November 1992

I222 Neuraminidase mutations further reduce oseltamivir susceptibility of Indonesian Clade 2.1 highly pathogenic Avian Influenza A(H5N1) viruses

scientific article (publication date: 2013)

Identification of Indonesian clade 2.1 highly pathogenic influenza A(H5N1) viruses with N294S and S246N neuraminidase substitutions which further reduce oseltamivir susceptibility.

scientific article

Identification of a human influenza type B strain with reduced sensitivity to neuraminidase inhibitor drugs

scientific article published in July 2004

In vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir

scientific article

Influenza Virus Neuraminidase Structure and Functions

scientific article published on 29 January 2019

Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance ⬇️

scientific article published on January 1, 2013

Inhibition of parainfluenza virus type 3 and Newcastle disease virus hemagglutinin-neuraminidase receptor binding: effect of receptor avidity and steric hindrance at the inhibitor binding sites.

scientific article published on December 2004

Interferon induction by measles virus.

scientific article published in January 1981

Isolation of very virulent Marek's disease viruses from vaccinated chickens in Australia

scientific article published on 01 June 1990

Liquid nitrogen storage of cultured T lymphocytes

scientific article published on 01 April 1985

Management of influenza virus infections with neuraminidase inhibitors: detection, incidence, and implications of drug resistance

scientific article

Mechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activity

scientific article

Meeting report: 4th ISIRV antiviral group conference: Novel antiviral therapies for influenza and other respiratory viruses

scientific article published on 9 February 2016

Mixed influenza A and B infections complicate the detection of influenza viruses with altered sensitivities to neuraminidase inhibitors

scientific article published on 23 April 2011

Mouse Saliva Inhibits Transit of Influenza Virus to the Lower Respiratory Tract by Efficiently Blocking Influenza Virus Neuraminidase Activity.

scientific article

Mutations conferring zanamivir resistance in human influenza virus N2 neuraminidases compromise virus fitness and are not stably maintained in vitro.

scientific article published on 5 August 2006

Neuraminidase inhibitor susceptibility network position statement: antiviral resistance in influenza A/H5N1 viruses.

scientific article

Neuraminidase inhibitor-resistant and -sensitive influenza B viruses isolated from an untreated human patient

scientific article

Neuraminidase inhibitors for the treatment and prevention of influenza

scientific article

Neuraminidase mutations conferring resistance to laninamivir lead to faster drug binding and dissociation

scientific article published on 9 December 2014

Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir.

scientific article

News about influenza B drug resistance that cannot be ignored

scientific article published in April 2007

Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant

scientific article published on 22 June 2019

Pertussigen enhances antigen-driven interferon-gamma production by sensitized lymphoid cells

scientific article published on 01 February 1986

Plaque formation assay for human parainfluenza virus type 1.

scientific article published on January 2011

Preparation of T cell growth factor free from interferon and factors stimulating hemopoietic cells and mast cells

scientific article published on 01 January 1982

Prevention and treatment of respiratory viral infections: Presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference

scientific article published on 18 November 2017

Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza viruses

scientific article

Reduced sensitivity of influenza A (H5N1) to oseltamivir

scientific article

Reduced susceptibility to all neuraminidase inhibitors of influenza H1N1 viruses with haemagglutinin mutations and mutations in non-conserved residues of the neuraminidase.

scientific article published on 11 June 2013

Resistance of influenza viruses to neuraminidase inhibitors--a review.

scientific article

Resistance to Neuraminidase Inhibitors Conferred by an R292K Mutation in a Human Influenza Virus H7N9 Isolate Can Be Masked by a Mixed R/K Viral Population ⬇️

scientific article published on July 16, 2013

Solid phase assay for comparing reactivation rates of neuraminidases of influenza wild type and resistant mutants after inhibitor removal.

scientific article published on 20 May 2014

Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses

scientific article

Structural and functional analysis of anti-influenza activity of 4-, 7-, 8- and 9-deoxygenated 2,3-difluoro-N-acetylneuraminic acid derivatives.

scientific article published on 3 February 2018

Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases ⬇️

scientific article published on October 28, 1997

Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding

scientific article published on 19 August 2006

Structure of an Influenza A virus N9 neuraminidase with a tetrabrachion-domain stalk

scientific article published on 23 January 2019

Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III

scientific article

Substitutions at H134 and in the 430-loop region in influenza B neuraminidases can confer reduced susceptibility to multiple neuraminidase inhibitors

scientific article published on 01 August 2020

Substrate, inhibitor, or antibody stabilizes the Glu 119 Gly mutant influenza virus neuraminidase.

scientific article published on July 1998

Surveillance for neuraminidase-inhibitor-resistant influenza viruses in Japan, 1996-2007.

scientific article published in January 2009

Taking down the FLAG! How insect cell expression challenges an established tag-system

scientific article (publication date: 2012)

Tethered neuraminidase inhibitors that bind an influenza virus: a first step towards a diagnostic method for influenza.

scientific article published in July 2003

The Interaction of Neuraminidase and Hemagglutinin Mutations in Influenza Virus in Resistance to 4-Guanidino-Neu5Ac2en ⬇️

scientific article published on June 20, 1998

The neuraminidases of MDCK grown human influenza A(H3N2) viruses isolated since 1994 can demonstrate receptor binding.

scientific article

The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

scientific article published on November 1, 1992

The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion

scientific article

The use of tetramethylbenzidine for solid phase immunoassays

scientific article published on 01 December 1990

Use of oligonucleotide probes for selecting potential high-yielding influenza reassortants

scientific article published on 01 November 1997

Zanamivir

Paulina is supported by:

About Paulina

Help