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List of works by Alexander Mellmann

A Robust One-Step Recombineering System for Enterohemorrhagic Escherichia coli

scientific article published in 2022

A geospatial analysis of flies and the spread of antimicrobial resistant bacteria.

scientific article published on 14 June 2016

A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis

scholarly article

Acinetobacter septicus sp. nov. association with a nosocomial outbreak of bacteremia in a neonatal intensive care unit

scientific article

Agitation down-regulates immunoglobulin binding protein EibG expression in Shiga toxin-producing Escherichia coli (STEC)

scientific article published on 6 March 2015

Analysis of collection of hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli

scientific article

Antibiotic-Mediated Modulations of Outer Membrane Vesicles in Enterohemorrhagic Escherichia coli O104:H4 and O157:H7.

scientific article published on 12 June 2017

Are cases of Methicillin-resistant Staphylococcus aureus clonal complex (CC) 398 among humans still livestock-associated?

scientific article published on 15 November 2014

Attack of the clones: whole genome-based characterization of two closely related enterohemorrhagic Escherichia coli O26 epidemic lineages

Automated DNA sequence-based early warning system for the detection of methicillin-resistant Staphylococcus aureus outbreaks

scientific article

Automatic MDCT Injectors: Hygiene and Efficiency of Disposable, Prefilled, and Multidosing Roller Pump Systems in Clinical Routine

scientific article published on 01 August 2011

Bacterial whole-genome sequencing revisited: portable, scalable, and standardized analysis for typing and detection of virulence and antibiotic resistance genes

scientific article published on 23 April 2014

Based Upon Repeat Pattern (BURP): an algorithm to characterize the long-term evolution of Staphylococcus aureus populations based on spa polymorphisms

scientific article

Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study

scientific article

Characterization of Escherichia coli isolates from hospital inpatients or outpatients with urinary tract infection

scientific article

Characterization of Escherichia coli strains isolated from patients with diarrhea in Sao Paulo, Brazil: identification of intermediate virulence factor profiles by multiplex PCR.

scientific article published on 20 April 2011

Characterization of clonal relatedness among the natural population of Staphylococcus aureus strains by using spa sequence typing and the BURP (based upon repeat patterns) algorithm

scientific article published on 4 June 2008

Chromosomal dynamism in progeny of outbreak-related sorbitol-fermenting enterohemorrhagic Escherichia coli O157:NM.

scientific article

Chromosomal instability in enterohaemorrhagic Escherichia coli O157:H7: impact on adherence, tellurite resistance and colony phenotype

scientific article

Clonal structure of Staphylococcus aureus colonizing children with sickle cell anaemia and healthy controls

scientific article

Co-detection of Panton-Valentine leukocidin encoding genes and cotrimoxazole resistance in Staphylococcus aureus in Gabon: implications for HIV-patients' care

scientific article

Comparative Secretome Analyses of Human and Zoonotic Isolates CC8, CC22, and CC398

scientific article published on 10 September 2018

Comparative phenotypic characterization of hybrid Shiga toxin-producing / uropathogenic Escherichia coli, canonical uropathogenic and Shiga toxin-producing Escherichia coli

scientific article published in 2021

Comparative virulence characterization of the Shiga toxin phage-cured Escherichia coli O104:H4 and enteroaggregative Escherichia coli

article

Comparison of asymptomatic bacteriuria Escherichia coli isolates from healthy individuals versus those from hospital patients shows that long-term bladder colonization selects for attenuated virulence phenotypes

scientific article published on 21 November 2011

Comparison of multilocus variable-number tandem-repeat analysis and multilocus sequence typing for differentiation of hemolytic-uremic syndrome-associated Escherichia coli (HUSEC) collection strains

scientific article

Comparison of traditional phenotypic identification methods with partial 5' 16S rRNA gene sequencing for species-level identification of nonfermenting Gram-negative bacilli

scientific article

Core Genome Multilocus Sequence Typing Scheme for High- Resolution Typing of Enterococcus faecium

scientific article

Core elements of the vegetative replication control of the Inc1 plasmid pO104_90 of Escherichia coli O104:H4 also regulate its transfer frequency

scientific article published on 18 July 2018

Cross-border comparison of the admission prevalence and clonal structure of meticillin-resistant Staphylococcus aureus

scientific article published on 6 February 2009

Defining and Evaluating a Core Genome Multilocus Sequence Typing Scheme for Genome-Wide Typing of Clostridium difficile

scientific article published on 4 April 2018

Defining and Evaluating a Core Genome Multilocus Sequence Typing Scheme for Whole-Genome Sequence-Based Typing of Listeria monocytogenes

scientific article

Detection and characterization of the fimbrial sfp cluster in enterohemorrhagic Escherichia coli O165:H25/NM isolates from humans and cattle

scientific article published on 31 October 2008

Detection of a phylogenetically distinct IMP-type metallo-β-lactamase, IMP-35, in a CC235 Pseudomonas aeruginosa from the Dutch-German border region (Euregio).

scientific article published on 22 January 2013

Detection of mecA- and mecC-Positive Methicillin-Resistant Staphylococcus aureus (MRSA) Isolates by the New Xpert MRSA Gen 3 PCR Assay

scientific article

Development and evaluation of a novel universal β-lactamase gene subtyping assay for blaSHV, blaTEM and blaCTX-M using clinical and livestock-associated Escherichia coli

scientific article published on 20 November 2014

Development and evaluation of a quality-controlled ribosomal sequence database for 16S ribosomal DNA-based identification of Staphylococcus species

scientific article

Distribution and phylogeny of immunoglobulin-binding protein G in Shiga toxin-producing Escherichia coli and its association with adherence phenotypes

scientific article

Distribution of capsular and surface polysaccharide serotypes of Staphylococcus aureus

scientific article published on 26 March 2007

Do complement factor H 402Y and C7 M allotypes predispose to (typical) haemolytic uraemic syndrome?

scientific article

Dynamic in vivo mutations within the ica operon during persistence of Staphylococcus aureus in the airways of cystic fibrosis patients.

scientific article

EUREGIO-Projekt MRSA-net Twente/Münsterland

scientific article published on 01 November 2006

Effects of antibiotics on Shiga toxin 2 production and bacteriophage induction by epidemic Escherichia coli O104:H4 strain

scientific article

Effizientes MRSA-Management

Effizientes MRSA-Management

Ensuring backwards compatibility: traditional genotyping efforts in the era of whole genome sequencing

scientific article published on 25 November 2014

Enterohaemorrhagic Escherichia coli O26:H11/H-: a human pathogen in emergence.

scientific article

Enterohemorrhagic E. coli (EHEC): Environmental-Vehicle-Human Interface

scholarly article published 9 December 2014

Enterohemorrhagic Escherichia coli O157 outer membrane vesicles induce interleukin 8 production in human intestinal epithelial cells by signaling via Toll-like receptors TLR4 and TLR5 and activation of the nuclear factor NF-κB

scientific article published on 19 June 2018

Enterohemorrhagic Escherichia coli O26:H11-Associated Hemolytic Uremic Syndrome: Bacteriology and Clinical Presentation

scientific article

Enterohemorrhagic Escherichia coli O26:H11/H-: a new virulent clone emerges in Europe

scientific article published in February 2013

Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis

scientific article (publication date: 2013)

Enterohemorrhagic Escherichia coli in human infection: in vivo evolution of a bacterial pathogen

scientific article

Epidemiology and pathogenesis of enterohaemorrhagic Escherichia coil.

scientific article

Erratum: Corrigendum: Updating benchtop sequencing performance comparison

scholarly article published in Nature Biotechnology

Establishment and evaluation of a core genome multilocus sequence typing scheme for whole-genome sequence-based typing of <i>Pseudomonas aeruginosa</i>

scientific article published on 16 December 2020

Evaluation of RIDOM, MicroSeq, and Genbank services in the molecular identification of Nocardia species

scientific article published in November 2003

Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to 16S rRNA gene sequencing for species identification of nonfermenting bacteria

scientific article

Evaluation of multiple-locus variable number of tandem repeats analysis for typing livestock-associated methicillin-resistant Staphylococcus aureus

scientific article

Evidence for cost reduction based on pre-admission MRSA screening in general surgery

scientific article published on 9 August 2007

Evidence-based infection control methods using spa genotyping for MRSA spread in hospitals

scientific article published in June 2005

Evolution and infection biology of hemolytic-uremic syndrome (HUS) associated E. coli (HUSEC)

scientific article

Evolution of enterohemorrhagic escherichia coli O26 based on single-nucleotide polymorphisms

scientific article

Evolutionary analysis and distribution of type III effector genes in pathogenic Escherichia coli from human, animal and food sources

scientific article published on 30 September 2010

From Infection to Detection: Imaging S. aureus – host interactions

Genome Sequences of the First WHO Repository of Platelet Transfusion-Relevant Bacterial Reference Strains

scientific article published on 20 July 2017

Genotypic Characterization of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Isolates of Clonal Complex 398 in Pigsty Visitors: Transient Carriage or Persistence?

scientific article published on 23 December 2019

Healthcare-Associated SARS-CoV-2 Transmission-Experiences from a German University Hospital

scientific article published on 08 September 2020

Hemolytic uremic syndrome in a 65-Year-old male linked to a very unusual type of stx2e- and eae-harboring O51:H49 shiga toxin-producing Escherichia coli

scientific article

Heteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6.

scientific article published on 10 January 2014

High Interlaboratory Reproducibility and Accuracy of Next-Generation-Sequencing-Based Bacterial Genotyping in a Ring Trial

scientific article

High burden of extended-spectrum β-lactamase-producing Enterobacteriaceae in Gabon

scientific article

High interlaboratory reproducibility of DNA sequence-based typing of bacteria in a multicenter study

scientific article

High interlaboratory reproducibility of matrix-assisted laser desorption ionization-time of flight mass spectrometry-based species identification of nonfermenting bacteria.

scientific article published on 23 September 2009

Highly Virulent Non-O157 Enterohemorrhagic Escherichia coli (EHEC) Serotypes Reflect Similar Phylogenetic Lineages, Providing New Insights into the Evolution of EHEC.

scientific article

Highly divergent Staphylococcus aureus isolates from African non-human primates

scientific article

Hygiene in der Radiologie: Was der Radiologe wissen sollte

scientific article published on 30 November 2012

Identification of intermediate in evolutionary model of enterohemorrhagic Escherichia coli O157

scientific article published in April 2012

In the centre of an epidemic: Fifteen years of LA-MRSA CC398 at the University Hospital Münster

scientific article

In vivo competition and horizontal gene transfer among distinct Staphylococcus aureus lineages as major drivers for adaptational changes during long-term persistence in humans

article

Inactivation of thyA in Staphylococcus aureus attenuates virulence and has a strong impact on metabolism and virulence gene expression.

scientific article

Integrating evolutionary aspects into dual-use discussion: the cases of influenza virus and enterohemorrhagic <i>Escherichia coli</i>

scientific article published in 2021

Intrahost genome alterations in enterohemorrhagic Escherichia coli

scientific article published on May 2009

Intrahost milieu modulates production of outer membrane vesicles, vesicle-associated Shiga toxin 2a and cytotoxicity in Escherichia coli O157:H7 and O104:H4.

scientific article

Is Africa the origin of major Haitian Staphylococcus aureus lineages?

scientific article

Is Shiga Toxin-Negative Escherichia coli O157:H7 Enteropathogenic or Enterohemorrhagic Escherichia coli? Comprehensive Molecular Analysis Using Whole-Genome Sequencing.

scientific article

L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling

scientific article published on 01 October 2019

Label-free imaging and spectroscopic analysis of intracellular bacterial infections

scientific article

Lability of the pAA Virulence Plasmid in Escherichia coli O104:H4: Implications for Virulence in Humans

scientific article

Livestock-associated methicillin-resistant Staphylococcus aureus (MRSA) as causes of human infection and colonization in Germany

scientific article

Low-level antimicrobial resistance of Enterobacteriaceae isolated from the nares of pig-exposed persons

scientific article published on 29 July 2015

MALDI-TOF Mass Spectrometry-Based Microbial Identification

MRSA eradication in dermatologic outpatients - theory and practice

article published in 2011

MRSA eradication in dermatologic outpatients - theory and practice

scientific article published on 29 December 2011

Management of superficial and deep-seated Staphylococcus aureus skin and soft tissue infections in sub-Saharan Africa: a post hoc analysis of the StaphNet cohort.

scientific article published on 17 April 2018

Microbiologic contamination and time efficiency of use of automatic MDCT injectors with prefilled syringes: Results of a clinical investigation

scientific article published in February 2010

Microbiologic contamination of automatic injectors at MDCT: experimental and clinical investigations

scientific article published in December 2008

Microevolution of epidemiological highly relevant non-O157 enterohemorrhagic Escherichia coli of serogroups O26 and O111

scientific article published on 10 August 2018

Molecular Characterization of Human Atypical Sorbitol-Fermenting Enteropathogenic Escherichia coli O157 Reveals High Diversity

scientific article

Molecular Typing of Enterobacteriaceae from Pig Holdings in North-Western Germany Reveals Extended- Spectrum and AmpC β-Lactamases Producing but no Carbapenem Resistant Ones.

scientific article published on 30 July 2015

Molecular characterization of Shigella spp. from patients in Gabon 2011-2013.

scientific article

Multicenter evaluation of a sequence-based protocol for subtyping Shiga toxins and standardizing Stx nomenclature

scientific article

Origin and Evolution of Hybrid Shiga Toxin-Producing and Uropathogenic Escherichia coli Strains of Sequence Type 141

scientific article published on 23 December 2019

Origin, evolution, and global transmission of community-acquired Staphylococcus aureus ST8.

scientific article published on 20 November 2017

Outbreak of MRSA in a Gynecology/Obstetrics Department during the COVID-19 Pandemic: A Cautionary Tale ⬇️

scientific article published on 23 March 2022

Phenotypic and genotypic traits of Shiga toxin-negative E. coli O157:H7/H(-) bovine and porcine strains

scientific article published in March 2009

Phosphorylation of influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity

scientific article published on 21 December 2015

Phylogenetic analysis of enterohemorrhagic Escherichia coli O157, Germany, 1987-2008

scientific article

Phylogenetic and molecular analysis of food-borne shiga toxin-producing Escherichia coli

scientific article

Phylogeny and disease association of Shiga toxin-producing Escherichia coli O91.

scientific article

Phylogeny and phenotypes of clinical and environmental Shiga toxin-producing Escherichia coli O174.

scientific article published on 27 August 2013

Phylogeny, clinical associations, and diagnostic utility of the pilin subunit gene (sfpA) of sorbitol-fermenting, enterohemorrhagic Escherichia coli O157:H-

scientific article published on October 2004

Point mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response

scientific article

Population dynamics among methicillin-resistant Staphylococcus aureus isolates in Germany during a 6-year period

scientific article

Prevalence and Epidemiology of Multidrug-Resistant Pathogens in the Food Chain and the Urban Environment in Northwestern Germany

scientific article published on 16 October 2020

Prevalence, virulence profiles, and clinical significance of Shiga toxin-negative variants of enterohemorrhagic Escherichia coli O157 infection in humans

scientific article

Prospective genomic characterization of the German enterohemorrhagic Escherichia coli O104:H4 outbreak by rapid next generation sequencing technology

scientific article published in 2011

RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells

scientific article published on 18 March 2020

Rapid high resolution genotyping of Francisella tularensis by whole genome sequence comparison of annotated genes ("MLST+").

scientific article published on 9 April 2015

Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting.

scientific article published on 24 August 2016

Real-time multiplex PCR for detecting Shiga toxin 2-producing Escherichia coli O104:H4 in human stools

scientific article

Recycling of Shiga toxin 2 genes in sorbitol-fermenting enterohemorrhagic Escherichia coli O157:NM

scientific article

Ridom TraceEdit: a DNA trace editor and viewer

scientific article published on 15 December 2005

Risk Factors for Long-Term Vancomycin-Resistant Enterococci Persistence-A Prospective Longitudinal Study

scientific article published on 26 September 2019

Semi-selective broth improves screening for methicillin-resistant Staphylococcus aureus

scientific article published on 3 February 2010

Sequence-based typing of flaB is a more stable screening tool than typing of flaA for monitoring of Campylobacter populations

scientific article published on October 2004

Shiga toxin 2e-producing Escherichia coli isolates from humans and pigs differ in their virulence profiles and interactions with intestinal epithelial cells

scientific article

Shiga toxin gene loss and transfer in vitro and in vivo during enterohemorrhagic Escherichia coli O26 infection in humans

scientific article published on 30 March 2007

Shiga toxin, cytolethal distending toxin, and hemolysin repertoires in clinical Escherichia coli O91 isolates

scientific article published on 29 April 2009

Shiga toxin-mediated hemolytic uremic syndrome: time to change the diagnostic paradigm?

scientific article

Shiga toxin-negative attaching and effacing Escherichia coli: distinct clinical associations with bacterial phylogeny and virulence traits and inferred in-host pathogen evolution

scientific article

Sorbitol-Fermenting Enterohemorrhagic Escherichia coli O157:H- Isolates from Czech Patients with Novel Plasmid Composition Not Previously Seen in German Isolates

scientific article published on 29 September 2017

Staphylococcal chromosomal cassette mec type I, spa type, and expression of Pls are determinants of reduced cellular invasiveness of methicillin-resistant Staphylococcus aureus isolates

scientific article published on 23 April 2007

Staphylococcal disease in Africa: another neglected 'tropical' disease

scientific article published on January 2013

Staphylococcus aureus complex from animals and humans in three remote African regions

scientific article

Staphylococcus aureus spa type t437: identification of the most dominant community-associated clone from Asia across Europe

scientific article published on 29 October 2014

Staphylococcus pettenkoferi sp. nov., a novel coagulase-negative staphylococcal species isolated from human clinical specimens

scientific article

State-wide surveillance of antibiotic resistance patterns and spa types of methicillin-resistant Staphylococcus aureus from blood cultures in North Rhine-Westphalia, 2011-2013.

scientific article published on 20 February 2015

Structural Insights into Escherichia coli Shiga Toxin (Stx) Glycosphingolipid Receptors of Porcine Renal Epithelial Cells and Inhibition of Stx-Mediated Cellular Injury Using Neoglycolipid-Spiked Glycovesicles

scientific article published on 19 November 2019

Structural and functional differences between disease-associated genes of enterohaemorrhagic Escherichia coli O111.

scientific article

Subtypes of the plasmid-encoded serine protease EspP in Shiga toxin-producing Escherichia coli: distribution, secretion, and proteolytic activity

scientific article

Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice

scientific article

The association of ESBL-producing Enterobacteriaceae (ESBL-E) carriage in humans with pigs - a reply

scientific article

The risk to import ESBL-producing Enterobacteriaceae and Staphylococcus aureus through chicken meat trade in Gabon

scientific article

Towards 3D modelling and imaging of infection scenarios at the single cell level using holographic optical tweezers and digital holographic microscopy

scientific article

Transcriptional adaptations during long-term persistence of Staphylococcus aureus in the airways of a cystic fibrosis patient

scientific article published on 29 October 2014

Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004–2011)

article

Updating benchtop sequencing performance comparison

scientific article published in April 2013

Urease genes in non-O157 Shiga toxin-producing Escherichia coli: mostly silent but valuable markers for pathogenicity.

scientific article

Variation of the polymorphic region X of the protein A gene during persistent airway infection of cystic fibrosis patients reflects two independent mechanisms of genetic change in Staphylococcus aureus

scientific article

Virulence factors and genotypes of Staphylococcus aureus from infection and carriage in Gabon

scientific article published on 20 May 2011

Virulence from vesicles: Novel mechanisms of host cell injury by Escherichia coli O104:H4 outbreak strain

scientific article

Whole genome sequencing as a tool to investigate a cluster of seven cases of listeriosis in Austria and Germany, 2011-2013

scientific article

Whole-Genome Sequencing Elucidates Epidemiology of Nosocomial Clusters of Acinetobacter baumannii

scientific article published on 29 June 2016

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