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List of works by Pablo Oppezzo

"Role of the B-cell receptor and the microenvironment in chronic lymphocytic leukemia''.

scientific article

Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation.

scientific article

Antibody-dependent cell cytotoxicity synapses form in mice during tumor-specific antibody immunotherapy

scientific article published on 22 June 2011

Autoanticorps, tolérance et auto-immunité

scientific article published on 01 July 2003

Binet's staging system and VH genes are independent but complementary prognostic indicators in chronic lymphocytic leukemia

scientific article published in November 2003

CCR4 expression in a case of cutaneous Richter’s transformation of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma (DLBCL) and in CLL patients with no skin manifestations

scientific article published on 01 July 2011

Chronic Lymphocytic Leukemia Cells Bind and Present the Erythrocyte Protein Band 3: Possible Role as Initiators of Autoimmune Hemolytic Anemia

scientific article published on 01 September 2008

Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation

scientific article (publication date: 15 May 2003)

Crystal structure of an enzymatically inactive trans-sialidase-like lectin from Trypanosoma cruzi: the carbohydrate binding mechanism involves residual sialidase activity

scientific article

Different isoforms of BSAP regulate expression of AID in normal and chronic lymphocytic leukemia B cells.

scientific article published on 23 November 2004

Dissecting chronic lymphocytic leukemia microenvironment signals in patients with unmutated disease: microRNA-22 regulates phosphatase and tensin homolog/AKT/FOXO1 pathway in proliferative leukemic cells

scientific article

Do CLL B cells correspond to naive or memory B-lymphocytes? Evidence for an active Ig switch unrelated to phenotype expression and Ig mutational pattern in B-CLL cells

scientific article published in December 2002

Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen

scientific article published on 22 April 2016

GALNT11 as a new molecular marker in chronic lymphocytic leukemia

scientific article published on 27 September 2013

Gene expression profiling of chronic lymphocytic leukemia can discriminate cases with stable disease and mutated Ig genes from those with progressive disease and unmutated Ig genes.

scientific article published in November 2005

Generation of a vector suite for protein solubility screening

scientific article published on 25 February 2014

HSP90 inhibitors decrease AID levels and activity in mice and in human cells.

scientific article

Human endogenous retrovirus np9 gene is over expressed in chronic lymphocytic leukemia patients

scientific article

Ibrutinib therapy downregulates AID enzyme and proliferative fractions in chronic lymphocytic leukemia

scientific article published on 27 February 2019

Idiotype-pulsed dendritic cells are able to induce antitumoral cytotoxic CD8 cells in chronic lymphocytic leukaemia

scientific article published on 01 January 2003

Immunoglobulin heavy chain V-D-J gene rearrangement and mutational status in Uruguayan patients with chronic lymphocytic leukemia

article

LPL protein in Chronic Lymphocytic Leukaemia have different origins in Mutated and Unmutated patients. Advances for a new prognostic marker in CLL

scientific article published on 28 June 2018

Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia: New Insights into Leukemic Progression

scientific article published on 5 December 2017

Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment

scientific article published on 25 July 2012

Lower levels of surface B-cell-receptor expression in chronic lymphocytic leukemia are associated with glycosylation and folding defects of the and CD79a chains

scientific article published on 09 December 2004

Methylation status regulates lipoprotein lipase expression in chronic lymphocytic leukemia

scientific article published on 21 June 2013

Molecular cloning of a monoclonal anti-tumor antibody specific for the Tn antigen and expression of an active single-chain Fv fragment.

scientific article published in August 1997

Multi-Compartment and Multi-Host Vector Suite for Recombinant Protein Expression and Purification.

scientific article published on 27 June 2018

Noninfectious complications in patients with pediatric-onset common variable immunodeficiency correlated with defects in somatic hypermutation but not in class-switch recombination

scientific article published on 3 October 2016

Overcoming the solubility problem in E. coli: available approaches for recombinant protein production

scientific article

Overview of High-Throughput Cloning Methods for the Post-genomic Era

scientific article published on 01 January 2019

Post-transcriptional regulation of inducible nitric oxide synthase in chronic lymphocytic leukemia B cells in pro- and antiapoptotic culture conditions ⬇️

scientific article published on January 1, 2004

Potent and specific inhibition of glycosidases by small artificial binding proteins (affitins)

scientific article published on 13 May 2014

Production and functional characterization of two mouse/human chimeric antibodies with specificity for the tumor-associated Tn-antigen.

scientific article published on June 2000

Retention and defective assembly of the B-cell receptor in the endoplasmic reticulum of chronic lymphocytic leukaemia B cells cannot be reverted upon CD40 ligand stimulation

scientific article published on 01 June 2003

S100-A9 protein in exosomes from chronic lymphocytic leukemia cells promotes NF-κB activity during disease progression.

scientific article published on 08 June 2017

Search for an aetiological virus candidate in chronic lymphocytic leukaemia by extensive transcriptome analysis ⬇️

scientific article published on April 10, 2012

Sphingosine kinase 1 participates in the activation, proliferation and survival of chronic lymphocytic leukemia cells.

scientific article published on 30 March 2017

Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase

scientific article

Structure of a human IgA1 Fab fragment at 1.55 Å resolution: potential effect of the constant domains on antigen-affinity modulation

scientific article

Surface localization of high-mobility group nucleosome-binding protein 2 on leukemic B cells from patients with chronic lymphocytic leukemia is related to secondary autoimmune hemolytic anemia.

scientific article published on 21 January 2015

The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia

scientific article published on 31 March 2005

The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406.

scientific article published on 15 August 2014

Tuning different expression parameters to achieve soluble recombinant proteins in E. coli: advantages of high-throughput screening.

scientific article published on 12 May 2011

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