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List of works by Caren C Helbing

A multi-omic approach to elucidate low-dose effects of xenobiotics in zebrafish (Danio rerio) larvae.

scientific article published on 18 November 2016

A nitrifier‐enriched microbial community contributes to the degradation of environmental <scp>DNA</scp>

scientific article published in 2023

Analysis of the Rana catesbeiana tadpole tail fin proteome and phosphoproteome during T3-induced apoptosis: identification of a novel type I keratin. ⬇️

scientific article

Antimicrobial peptides from Rana [Lithobates] catesbeiana: Gene structure and bioinformatic identification of novel forms from tadpoles

scientific article published in Scientific Reports

Behavioral and molecular analyses of olfaction-mediated avoidance responses of Rana (Lithobates) catesbeiana tadpoles: Sensitivity to thyroid hormones, estrogen, and treated municipal wastewater effluent.

scientific article

Biological effects of the anti-parasitic chemotherapeutant emamectin benzoate on a non-target crustacean, the spot prawn (Pandalus platyceros Brandt, 1851) under laboratory conditions

scientific article published on 28 October 2011

Cadmium-induced olfactory dysfunction in rainbow trout: Effects of binary and quaternary metal mixtures.

scientific article

Changes in hormone and stress-inducing activities of municipal wastewater in a conventional activated sludge wastewater treatment plant

scientific article published on 3 September 2014

Characterization of gene expression endpoints during postembryonic development of the northern green frog (Rana clamitans melanota).

scientific article published in May 2013

Chronic sublethal exposure to silver nanoparticles disrupts thyroid hormone signaling during Xenopus laevis metamorphosis

scientific article published on 12 December 2014

Comparison of thyroid hormone-dependent gene responses in vivo and in organ culture of the American bullfrog (Rana (Lithobates) catesbeiana) lung

scientific article published on 9 October 2015

C‐fin: A cultured frog tadpole tail fin biopsy approach for detection of thyroid hormone‐disrupting chemicals ⬇️

scientific article published on February 1, 2010

De novo Transcriptome Assemblies of Rana (Lithobates) catesbeiana and Xenopus laevis Tadpole Livers for Comparative Genomics without Reference Genomes

scientific article published on 29 June 2015

De novo assembly of the ringed seal (Pusa hispida) blubber transcriptome: A tool that enables identification of molecular health indicators associated with PCB exposure

scientific article published on 03 February 2017

Decreased cyclin-dependent kinase activity promotes thyroid hormone-dependent tail regression in Rana catesbeiana

scientific article published on 16 January 2007

Development of a non-lethal method for evaluating transcriptomic endpoints in Arctic grayling (Thymallus arcticus).

scientific article published on 7 May 2014

Distinctive gene profiles occur at key points during natural metamorphosis in the Xenopus laevis tadpole tail

scientific article published in December 2002

Distinctive metabolite profiles in in-migrating Sockeye salmon suggest sex-linked endocrine perturbation

scientific article published on 24 September 2014

Effect of low dose exposure to the herbicide atrazine and its metabolite on cytochrome P450 aromatase and steroidogenic factor-1 mRNA levels in the brain of premetamorphic bullfrog tadpoles (Rana catesbeiana).

scientific article

Effects of acute exposure to the non-steroidal anti-inflammatory drug ibuprofen on the developing North American Bullfrog (Rana catesbeiana) tadpole

scientific article published on 15 August 2014

Effects of triclocarban, triclosan, and methyl triclosan on thyroid hormone action and stress in frog and mammalian culture systems.

scientific article

Enabling comparative gene expression studies of thyroid hormone action through the development of a flexible real-time quantitative PCR assay for use across multiple anuran indicator and sentinel species.

scientific article published on 22 January 2014

Enabling robust environmental DNA assay design with “unikseq” for the identification of taxon‐specific regions within whole mitochondrial genomes

scientific article published in 2023

Enumeration potential of environmental <scp>DNA</scp> for Pacific salmon stock assessments

scientific article published in 2023

Environmental influences on the epigenomes of herpetofauna and fish.

scientific article

Estrogenic environmental contaminants alter the mRNA abundance profiles of genes involved in gonadal differentiation of the American bullfrog

scientific article published on 6 April 2015

Evaluating the treatment of a synthetic wastewater containing a pharmaceutical and personal care product chemical cocktail: compound removal efficiency and effects on juvenile rainbow trout.

scientific article published on 11 June 2014

Evaluation of Gene Bioindicators in the Liver and Caudal Fin of Juvenile Pacific Coho Salmon in Response to Low Sulfur Marine Diesel Seawater-Accommodated Fraction Exposure

scientific article published on 18 January 2019

Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors

scientific article

Evaluation of the effect of acetochlor on thyroid hormone receptor gene expression in the brain and behavior of Rana catesbeiana tadpoles.

scientific article published in September 2006

Evaluation of the effects of titanium dioxide nanoparticles on cultured Rana catesbeiana tailfin tissue.

scientific article

Evidence of disruption in estrogen-associated signaling in the liver transcriptome of in-migrating sockeye salmon of British Columbia, Canada ⬇️

scientific article published on October 25, 2012

Expansion of the known distribution of the coastal tailed frog, Ascaphus truei, in British Columbia, Canada, using robust eDNA detection methods

article

Exposure to tetrabromobisphenol-A alters TH-associated gene expression and tadpole metamorphosis in the Pacific tree frog Pseudacris regilla.

scientific article published on 5 May 2006

Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis ⬇️

scientific article

Expression profiles of novel thyroid hormone-responsive genes and proteins in the tail of Xenopus laevis tadpoles undergoing precocious metamorphosis.

scientific article published on 10 April 2003

Gene expression profiling and environmental contaminant assessment of migrating Pacific salmon in the Fraser River watershed of British Columbia

scientific article published on 18 September 2009

Gene expression profiling in the deep water horse mussel Modiolus modiolus (L.) located near a marine municipal wastewater outfall.

scientific article published on 17 April 2009

Genistein prevents thyroid hormone-dependent tail regression of Rana catesbeiana tadpoles by targetting protein kinase C and thyroid hormone receptor alpha.

scientific article published in March 2007

Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain

scientific article published on 23 February 2007

Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb

scientific article published on 23 February 2007

Identification of organ-autonomous constituents of the molecular memory conferred by thyroid hormone exposure in cold temperature-arrested metamorphosing Rana (Lithobates) catesbeiana tadpoles.

scientific article published on 7 January 2016

Impact of wastewater treatment configuration and seasonal conditions on thyroid hormone disruption and stress effects in Rana catesbeiana tailfin.

scientific article published on 15 November 2013

Implementation of Novel Design Features for qPCR-Based eDNA Assessment

scientific article

In Memoriam: Louis J. Guillette, Jr.

scientific article published on October 2015

Influence of Nitrate and Nitrite on Thyroid Hormone Responsive and Stress-Associated Gene Expression in Cultured Rana catesbeiana Tadpole Tail Fin Tissue ⬇️

scientific article published on April 4, 2012

Influence of temperature on thyroid hormone signaling and endocrine disruptor action in Rana (Lithobates) catesbeiana tadpoles

scientific article published on 9 January 2015

Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: hurdles, achievements, and future outlook

scientific article published on January 2010

Local contamination, and not feeding preferences, explains elevated PCB concentrations in Labrador ringed seals (Pusa hispida).

scientific article published on 26 February 2015

Metabolomic insights into system-wide coordination of vertebrate metamorphosis.

scientific article published on 05 February 2014

Minimally invasive transcriptome profiling in salmon: detection of biological response in rainbow trout caudal fin following exposure to environmental chemical contaminants

scientific article published on 4 September 2013

Mining Amphibian and Insect Transcriptomes for Antimicrobial Peptide Sequences with rAMPage

scientific article published in 2022

Modulation of thyroid hormone-dependent gene expression in Xenopus laevis by INhibitor of Growth (ING) proteins

scientific article

Modulators of inhibitor of growth (ING) family expression in development and disease.

scientific article published on May 2009

Molecular cloning of the estrogen and progesterone receptors of the American alligator

scientific article published on March 2004

Molecular profiling of marine fauna: integration of omics with environmental assessment of the world's oceans.

scientific article

Multiple ING1 and ING2 genes in Xenopus laevis and evidence for differential association of thyroid hormone receptors and ING proteins to their promoters

scientific article published on 14 December 2007

Multiple variants of the ING1 and ING2 tumor suppressors are differentially expressed and thyroid hormone-responsive in Xenopus laevis

scientific article published in October 2005

Nanometals induce stress and alter thyroid hormone action in amphibia at or below North American water quality guidelines

scientific article published on November 2010

PCB related effects thresholds as derived through gene transcript profiles in locally contaminated ringed seals (Pusa hispida)

scientific article published on 27 October 2014

PCB-associated changes in mRNA expression in killer whales (Orcinus orca) from the NE Pacific Ocean.

scientific article

PCBs are associated with altered gene transcript profiles in arctic Beluga Whales (Delphinapterus leucas).

scientific article published on 19 February 2014

Peering into molecular mechanisms of action with frogSCOPE.

scientific article published on 13 January 2010

Phenotypic plasticity in the hepatic transcriptome of the European common frog (Rana temporaria): the interplay between environmental induction and geographical lineage on developmental response.

scientific article

Phylogenetic analysis of the ING family of PHD finger proteins

scientific article

Polychlorinated Biphenyl-Related Alterations of the Expression of Essential Genes in Harbour Seals (Phoca vitulina) from Coastal Sites in Canada and the United States.

scientific article

Polychlorinated biphenyl profiles in ringed seals (Pusa Hispida) reveal historical contamination by a military radar station in Labrador, Canada

scientific article published on 29 January 2014

Quantification of 11 thyroid hormones and associated metabolites in blood using isotope-dilution liquid chromatography tandem mass spectrometry

scientific article

Relationship between mRNA biomarker candidates and location near a marine municipal wastewater outfall in the benthic indicator species Modiolus modiolus (L.) ⬇️

scientific article published on June 6, 2011

Rethinking the biological relationships of the thyroid hormones, l-thyroxine and 3,5,3'-triiodothyronine

scientific article published on 7 April 2016

Revising the range of Rocky Mountain tailed frog, <i>Ascaphus montanus</i>, in British Columbia, Canada, using environmental DNA methods

scientific article published in 2020

Roscovitine inhibits thyroid hormone-induced tail regression of the frog tadpole and reveals a role for cyclin C/Cdk8 in the establishment of the metamorphic gene expression program.

scientific article published in December 2008

Satellite telemetry informs PCB source apportionment in a mobile, high trophic level marine mammal: the ringed seal (Pusa hispida).

scientific article published on 30 October 2014

Sequential up-regulation of thyroid hormone beta receptor, ornithine transcarbamylase, and carbamyl phosphate synthetase mRNAs in the liver of Rana catesbeiana tadpoles during spontaneous and thyroid hormone-induced metamorphosis

scientific article published on January 1, 1992

Spatio-temporal characterization of retinal opsin gene expression during thyroid hormone-induced and natural development of rainbow trout.

scientific article

Specific time of exposure during tadpole development influences biological effects of the insecticide carbaryl in green frogs (Lithobates clamitans).

scientific article

Temporal expression of two cytochrome P450 aromatase isoforms during development in Oreochromis mossambicus, in association with histological development.

scientific article published on 9 September 2008

The North American bullfrog draft genome provides insight into hormonal regulation of long noncoding RNA.

scientific article

The bactericidal agent triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development.

scientific article published on 29 September 2006

The effect of silica desiccation under different storage conditions on filter-immobilized environmental DNA

publication published on 21 March 2021

The metamorphosis of amphibian toxicogenomics.

scientific article published on 14 March 2012

The need for robust qPCR‐based eDNA detection assays in environmental monitoring and species inventories

scientific article published on 19 November 2020

Thyroid hormone-dependent development in Xenopus laevis: a sensitive screen of thyroid hormone signaling disruption by municipal wastewater treatment plant effluent

scientific article

Toxicity of glyphosate-based pesticides to four North American frog species.

scientific article

Triclosan affects the thyroid axis of amphibians

scientific article published on 18 August 2011

Triclosan affects thyroid hormone-dependent metamorphosis in anurans

scientific article published on 11 November 2010

Triclosan exposure alters postembryonic development in a Pacific tree frog (Pseudacris regilla) Amphibian Metamorphosis Assay (TREEMA).

scientific article

Use of electro-olfactography to measure olfactory acuity in the North American bullfrog (Lithobates (Rana) catesbeiana) tadpole

scientific article

Use of heterologous cDNA arrays and organ culture in the detection of thyroid hormone-dependent responses in a sentinel frog, Rana catesbeiana.

scientific article published on 12 December 2005

Xenobiotics Produce Distinct Metabolomic Responses in Zebrafish Larvae (Danio rerio).

scientific article

qPCR-based eDNA workflow for humic-rich lake sediments: Combined use of sedimentary DNA (sedDNA) and Indigenous Knowledge in reconstructing historical fish records

scientific article published in 2023

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