List of works - Jeremy Green

3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta

scientific article

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: potent and selective p70S6 kinase inhibitors.

scientific article published on 9 July 2009

Application of design of experiments (DoE) optimization to the one-pot synthesis of 4,6-dihydropteridinones

scientific article published on 9 September 2015

Application of the Photoredox Coupling of Trifluoroborates and Aryl Bromides to Analog Generation Using Continuous Flow.

scientific article

Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors

scientific article

Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part I: aminoalkoxypyrimidine carboxamides.

scientific article published on 17 April 2012

Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles

scientific article published on July 2016

Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors

scientific article

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

scientific article

Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions

scientific article published on 28 November 2017

ROCK inhibitors 2. Improving potency, selectivity and solubility through the application of rationally designed solubilizing groups

scientific article published on 21 June 2018

ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors

scientific article published on 19 June 2018

Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide

scientific article

Synthesis of Cycloalkyl Substituted 7-Azaindoles via Photoredox Nickel Dual Catalytic Cross-Coupling in Batch and Continuous Flow

scientific article published on 18 November 2016

Synthesis of β-Ketosulfonamides Derived from Amino Acids and Their Conversion to β-Keto-α,α-difluorosulfonamides via Electrophilic Fluorination.

scientific article

The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor.

scientific article published on 28 July 2011

What Do Medicinal Chemists Actually Make? A 50-Year Retrospective ⬇️

scientific article published on August 31, 2011

List of works by Jeremy Green

3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: potent and selective p70S6 kinase inhibitors.

Application of design of experiments (DoE) optimization to the one-pot synthesis of 4,6-dihydropteridinones

Application of the Photoredox Coupling of Trifluoroborates and Aryl Bromides to Analog Generation Using Continuous Flow.

Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors

Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part I: aminoalkoxypyrimidine carboxamides.

Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles

Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions

ROCK inhibitors 2. Improving potency, selectivity and solubility through the application of rationally designed solubilizing groups

ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors

Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide

Synthesis of Cycloalkyl Substituted 7-Azaindoles via Photoredox Nickel Dual Catalytic Cross-Coupling in Batch and Continuous Flow

Synthesis of β-Ketosulfonamides Derived from Amino Acids and Their Conversion to β-Keto-α,α-difluorosulfonamides via Electrophilic Fluorination.

The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor.

What Do Medicinal Chemists Actually Make? A 50-Year Retrospective ⬇️