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List of works by Leonard G. Luyt

18F-Labeled PET Probe Targeting Enhancer of Zeste Homologue 2 (EZH2) for Cancer Imaging

scientific article published on 27 February 2019

A Compact and Synthetically Accessible Fluorine-18 Labelled Cyclooctyne Prosthetic Group for Labelling of Biomolecules by Copper-Free Click Chemistry

scientific article published on 23 July 2018

A Decade's Progress in the Development of Molecular Imaging Agents Targeting the Growth Hormone Secretagogue Receptor

scientific article published on 01 January 2020

A Hyaluronan-binding Peptide (P15-1) Reduces Inflammatory and Catabolic Events in IL-1β-treated Human Articular Chondrocytes

scientific article published on 29 January 2020

A RHAMM mimetic peptide blocks hyaluronan signaling and reduces inflammation and fibrogenesis in excisional skin wounds.

scientific article

A dual modality 99mTc/Re(i)-labelled T140 analogue for imaging of CXCR4 expression

scientific article published on 01 January 2019

A fast, reproducible and low-cost method for sequence deconvolution of 'on-bead' peptides via 'on-target' maldi-TOF/TOF mass spectrometry

scientific article

A study of 99mTc/Re-tricarbonyl complexes of 4-amino-1,8-naphthalimides

scientific article published on 06 September 2019

A trithiolate tripodal bifunctional ligand for the radiolabeling of peptides with gallium(III).

scientific article published in September 2002

A truncated RHAMM protein for discovering novel therapeutic peptides

scientific article published on 18 September 2018

Amino-Substituted 2,2'-Bipyridine Ligands as Fluorescent Indicators for ZnII and Applications for Fluorescence Imaging of Prostate Cells

scientific article published on 05 September 2018

An N2S2 bifunctional chelator for technetium-99m and rhenium: complexation, conjugation, and epimerization to a single isomer

scientific article published on 01 May 1999

An integrated imaging probe design: the synthesis of (99m)Tc/Re-containing macrocyclic peptide scaffolds.

scientific article published on 11 November 2014

Bridging computational modeling with amino acid replacements to investigate GHS-R1a-peptidomimetic recognition.

scientific article published on 4 August 2016

Characterization of a far-red analog of ghrelin for imaging GHS-R in P19-derived cardiomyocytes.

scientific article published on 25 January 2014

Design and characterization of a fluorescent ghrelin analog for imaging the growth hormone secretagogue receptor 1a

scientific article (publication date: 10 December 2011)

Design and synthesis of functionalized cyclopentadienyl tricarbonylmetal complexes for technetium-94m PET imaging of estrogen receptors.

scientific article

Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries.

scientific article

Development of Candidates for Positron Emission Tomography (PET) Imaging of Ghrelin Receptor in Disease: Design, Synthesis, and Evaluation of Fluorine-Bearing Quinazolinone Derivatives.

scientific article published on 12 January 2018

Development of a [68Ga]-ghrelin analogue for PET imaging of the ghrelin receptor (GHS-R1a)

scientific article published on 17 September 2018

Discovery of novel integrin ligands from combinatorial libraries using a multiplex "beads on a bead" approach.

scientific article

Dual-modal magnetic resonance and fluorescence imaging of atherosclerotic plaques in vivo using VCAM-1 targeted tobacco mosaic virus

scientific article

Dynamics of the Ghrelin/Growth Hormone Secretagogue Receptor System in the Human Heart Before and After Cardiac Transplantation

scientific article published on 14 February 2019

Evaluation of Anisole-Substituted Boron Difluoride Formazanate Complexes for Fluorescence Cell Imaging.

scientific article

Fluorine and rhenium substituted ghrelin analogues as potential imaging probes for the growth hormone secretagogue receptor.

scientific article

Ghrelin receptor as a novel imaging target for prostatic neoplasms ⬇️

scientific article published on September 14, 2011

High Affinity Fluorescent Probe for Proteinase-Activated Receptor 2 (PAR2)

scientific article published on 06 June 2019

Identification of a selective G-quadruplex DNA binder using a multistep virtual screening approach.

scientific article

Identification, design and synthesis of tubulin-derived peptides as novel hyaluronan mimetic ligands for the receptor for hyaluronan-mediated motility (RHAMM/HMMR).

scientific article published on 12 October 2015

Imaging of Homeostatic, Neoplastic, and Injured Tissues by HA-Based Probes ⬇️

scientific article published on December 12, 2011

Incorporation of Fluorine into an OBOC Peptide Library by Copper-Free Click Chemistry toward the Discovery of PET Imaging Agents

scientific article published on 06 February 2020

Intravital Imaging of Human Prostate Cancer Using Viral Nanoparticles Targeted to Gastrin‐Releasing Peptide Receptors ⬇️

scientific article published on April 26, 2011

Investigation of isomer formation upon coordination of bifunctional histidine analogues with 99mTc/Re(CO)3

scientific article published on 23 January 2012

Molecular Engineering of Thiazole Orange Dye: Change of Fluorescent Signaling from Universal to Specific upon Binding with Nucleic Acids in Bioassay.

scientific article published on 11 January 2016

Molecular imaging probes derived from natural peptides.

scientific article published on 25 February 2016

Molecular targeted viral nanoparticles as tools for imaging cancer

scientific article

Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential as 18F-Labeled Positron Emission Tomography Probes via I-SPANC

scientific article published on 08 November 2019

Novel Methods of Determining Urinary Calculi Composition: Petrographic Thin Sectioning of Calculi and Nanoscale Flow Cytometry Urinalysis.

scientific article

Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor

scientific article published on 23 August 2018

RHAMM promotes interphase microtubule instability and mitotic spindle integrity through MEK1/ERK1/2 activity

scientific article

Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis.

scientific article published on 20 February 2017

Single Amino Acid Replacement in G-7039 Leads to a 70-fold Increase in Binding toward GHS-R1a

scientific article published on 30 September 2019

Single isomer technetium-99m tamoxifen conjugates

scientific article published on 01 March 2000

Structure-Activity Study of Ghrelin(1-8) Resulting in High Affinity Fluorine-Bearing Ligands for the Ghrelin Receptor.

scientific article

Synthesis and cell-based screening of one-bead-one-compound peptide libraries.

scientific article published on January 2015

Synthesis of Rhenium‐Centric Reverse Turn Mimics ⬇️

scientific article published on September 3, 2012

Synthesis, radiometal labeling and in vitro evaluation of a targeted PPIX derivative.

scientific article

The Chimera That Curbs Appetite

scientific article published on 03 December 2018

The development of a near infrared inulin optical probe for measuring glomerular filtration rate

scientific article published on 10 November 2018

Viral nanoparticles decorated with novel EGFL7 ligands enable intravital imaging of tumor neovasculature.

scientific article published on 11 August 2017

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