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List of works by Juan Chen

"Zipper" molecular beacons: a generalized strategy to optimize the performance of activatable protease probes

scientific article published on 14 September 2009

A Nanoemulsion with A Porphyrin Shell for Cancer Theranostics

scientific article published on 05 September 2019

A PEGylation-Free Biomimetic Porphyrin Nanoplatform for Personalized Cancer Theranostics

scientific article

A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production

scientific article

Ablation of hypoxic tumors with dose-equivalent photothermal, but not photodynamic, therapy using a nanostructured porphyrin assembly

scientific article published on 12 February 2013

Activatable photosensitizers for imaging and therapy.

scientific article published on May 2010

Activation Kinetics of Zipper Molecular Beacons

Attenuation of nontargeted cell-kill using a high-density lipoprotein-mimicking peptide--phospholipid nanoscaffold.

scientific article published on 4 May 2011

Biologically-targeted detection of primary and micro-metastatic ovarian cancer

scientific article published on 25 May 2013

Biomimetic nanocarrier for direct cytosolic drug delivery.

scientific article published on January 2009

Chlorosome-Inspired Synthesis of Templated Metallochlorin-Lipid Nanoassemblies for Biomedical Applications

scientific article published on 25 March 2016

Conformational modulation of in vitro activity of cyclic RGD peptides via aziridine aldehyde-driven macrocyclization chemistry.

scientific article

Cytosolic delivery of LDL nanoparticle cargo using photochemical internalization.

scientific article published on 23 February 2011

Effect of removing Kupffer cells on nanoparticle tumor delivery.

scientific article published on 5 December 2017

Efficient Systemic Delivery of siRNA by Using High-Density Lipoprotein-Mimicking Peptide Lipid Nanoparticles ⬇️

scientific article published on July 26, 2012

Efficient cytosolic delivery of siRNA using HDL-mimicking nanoparticles.

scientific article published on 27 January 2011

Evaluation of Novel Imaging Devices for Nanoparticle-Mediated Fluorescence-Guided Lung Tumor Therapy

scientific article published on 08 February 2019

FRET quenching of photosensitizer singlet oxygen generation

scientific article

Facile Synthesis of Advanced Photodynamic Molecular Beacon Architectures

scientific article published on 01 June 2010

HDL-mimicking peptide-lipid nanoparticles with improved tumor targeting

scientific article

Imaging of specific activation of photodynamic molecular beacons in breast cancer vertebral metastases

scientific article published on 24 May 2011

Imaging the cytosolic drug delivery mechanism of HDL-like nanoparticles.

scientific article

Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency.

scientific article published on 22 May 2014

Investigating the specific uptake of EGF-conjugated nanoparticles in lung cancer cells using fluorescence imaging.

scientific article

Killer beacons for combined cancer imaging and therapy.

scientific article published on January 2007

Learning from biology: synthetic lipoproteins for drug delivery

scientific article

Ligand conjugated low-density lipoprotein nanoparticles for enhanced optical cancer imaging in vivo.

scientific article published on 12 April 2007

Lipid-based nanoparticles in the systemic delivery of siRNA.

scientific article published on January 2014

Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents

scientific article

Lipoprotein-based nanoparticles rescue the memory loss of mice with Alzheimer's disease by accelerating the clearance of amyloid-beta

scientific article

Long-Circulating Prostate-Specific Membrane Antigen-Targeted NIR Phototheranostic Agent

scientific article published on 19 November 2019

Low-density lipoprotein nanoparticles as magnetic resonance imaging contrast agents

scientific article

Matrix metalloproteinase-based photodynamic molecular beacons for targeted destruction of bone metastases in vivo

scientific article published on 16 February 2016

Mixed and Matched Metallo-Nanotexaphyrin for Customizable Biomedical Imaging

scientific article published on 13 September 2018

Modulation of reactive oxygen species photogeneration of bacteriopheophorbide a derivatives by exocyclic E-ring opening and charge modifications.

scientific article published on 20 December 2013

Molecular imaging in drug development: Update and challenges for radiolabeled antibodies and nanotechnology.

scientific article published on 22 July 2017

Multimodal Image-Guided Surgical and Photodynamic Interventions in Head and Neck Cancer: From Primary Tumor to Metastatic Drainage

scientific article published on 13 October 2015

Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head-and-Neck Cancer Rabbit Model

scientific article published on 18 August 2015

Multimodal bacteriochlorophyll theranostic agent.

scientific article

Multipronged Biomimetic Approach To Create Optically Tunable Nanoparticles

scientific article published on 06 June 2018

Nanoparticle targeted folate receptor 1-enhanced photodynamic therapy for lung cancer.

scientific article published on 5 September 2017

Nanoparticle-Enabled Selective Destruction of Prostate Tumor Using MRI-Guided Focal Photothermal Therapy

scientific article

Nanoparticle-enabled, image-guided treatment planning of target specific RNAi therapeutics in an orthotopic prostate cancer model.

scientific article published on 6 April 2014

Nanostructure‐Driven Indocyanine Green Dimerization Generates Ultra‐Stable Phototheranostics Nanoparticles

scientific article published on 31 May 2023

Nanotexaphyrin: One-Pot Synthesis of a Manganese Texaphyrin-Phospholipid Nanoparticle for Magnetic Resonance Imaging

scientific article published on 13 April 2016

Naphthalocyanine-reconstituted LDL nanoparticles for in vivo cancer imaging and treatment.

scientific article published on January 2007

Optical glucose analogs of aminolevulinic acid for fluorescence-guided tumor resection and photodynamic therapy

scientific article published on August 2014

Organized Aggregation of Porphyrins in Lipid Bilayers for Third Harmonic Generation Microscopy.

scientific article published on 29 September 2015

Peptide-based molecular beacons for cancer imaging and therapy.

scientific article published on 19 February 2010

Peptide-based pharmacomodulation of a cancer-targeted optical imaging and photodynamic therapy agent.

scientific article published on 14 February 2007

Personalized siRNA-Nanoparticle Systemic Therapy using Metastatic Lymph Node Specimens Obtained with EBUS-TBNA in Lung Cancer.

scientific article published on 9 October 2017

Photodynamic molecular beacon as an activatable photosensitizer based on protease-controlled singlet oxygen quenching and activation

scholarly article

Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers

scientific article published on January 2009

Photodynamic therapy enables tumor-specific ablation in preclinical models of thyroid cancer

scientific article published on 01 February 2020

Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models.

scientific article

Porphyrin FRET Acceptors for Apoptosis Induction and Monitoring

scientific article published on 28 October 2011

Porphyrin Nanodroplets: Sub-micrometer Ultrasound and Photoacoustic Contrast Imaging Agents

scientific article published on 3 December 2015

Porphyrin-lipid stabilized paclitaxel nanoemulsion for combined photodynamic therapy and chemotherapy

scientific article published on 25 May 2021

PorphyrinHDL: A Novel Photosensitizing Nanoparticle for Lung Cancer Therapy

scientific article published on 11 October 2018

Porphysome nanoparticles for enhanced photothermal therapy in a patient-derived orthotopic pancreas xenograft cancer model: a pilot study

article

Preclinical investigation of folate receptor-targeted nanoparticles for photodynamic therapy of malignant pleural mesothelioma

scientific article published on 07 September 2018

Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation

scientific article published in September 2004

QUANTIFYING NANOPARTICLE TRANSPORT IN VIVO USING HYPERSPECTRAL IMAGING WITH A DORSAL SKINFOLD WINDOW CHAMBER.

scientific article published on October 2012

Stable J-Aggregation of an aza-BODIPY-Lipid in a Liposome for Optical Cancer Imaging

scientific article published on 13 August 2019

Stable J-aggregation enabled dual photoacoustic and fluorescence nanoparticles for intraoperative cancer imaging

scientific article published on 5 January 2016

Subtherapeutic Photodynamic Treatment Facilitates Tumor Nanomedicine Delivery and Overcomes Desmoplasia

scientific article published on 10 December 2020

Synthesis and evaluation of a stable bacteriochlorophyll-analog and its incorporation into high-density lipoprotein nanoparticles for tumor imaging.

scientific article published on November 2009

Tailored theranostic apolipoprotein E3 porphyrin-lipid nanoparticles target glioblastoma.

scientific article published on 23 May 2017

Tailoring Porphyrin Conjugation for Nanoassembly-Driven Phototheranostic Properties

scientific article published on 01 April 2019

Tailoring nanoparticle designs to target cancer based on tumor pathophysiology.

scientific article published on 16 February 2016

Targeting-triggered porphysome nanostructure disruption for activatable photodynamic therapy.

scientific article published on 27 January 2014

The dose threshold for nanoparticle tumour delivery

scientific article published on 10 August 2020

Theranostic lipid nanoparticles for cancer medicine.

scientific article published on January 2015

Topical MMP beacon enabled fluorescence-guided resection of oral carcinoma

scientific article published on 29 February 2016

Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer.

scientific article

Use of Porphysomes to detect primary tumour, lymph node metastases, intra-abdominal metastases and as a tool for image-guided lymphadenectomy: proof of concept in endometrial cancer

scientific article published on 13 April 2019

Using Fluorescence Imaging to Track Drug Delivery and Guide Treatment Planning In Vivo

scientific article published in January 2016

Using molecular beacons for cancer imaging and treatment

scientific article

Using the singlet oxygen scavenging property of carotenoid in photodynamic molecular beacons to minimize photodamage to non-targeted cells

scientific article published on 20 August 2007

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