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List of works by Jean-Charles Grivel

A highly sensitive and dynamic immunofluorescent cytometric bead assay for the detection of HIV-1 p24.

scientific article published on 6 January 2009

A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2

scientific article

A universal nanoparticle cell secretion capture assay

scientific article published on 20 September 2012

Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.

scientific article published on 8 February 2007

Activation of T lymphocytes in atherosclerotic plaques

scientific article published on 29 September 2011

Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues

scientific article

Analysis of Extracellular Vesicles Using Magnetic Nanoparticles in Blood of Patients with Acute Coronary Syndrome

scientific article published on April 2016

Analysis of RBC-microparticles in stored whole blood bags - a promising marker to detect blood doping in sports?

scientific article published on 4 May 2017

Antigenic composition of single nano-sized extracellular blood vesicles

scientific article published on 3 December 2014

Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study

scientific article published on 17 May 2008

Blockade of CC chemokine receptor 5 (CCR5)-tropic human immunodeficiency virus-1 replication in human lymphoid tissue by CC chemokines.

scientific article published on May 1998

Breakdown of Tolerance to a Neo-Self Antigen in Double Transgenic Mice in Which B Cells Present the Antigen

scientific article published on 01 May 2000

Bystander CD4+ T lymphocytes survive in HIV-infected human lymphoid tissue

scientific article published in March 2003

CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue.

scientific article published on March 1999

CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis

scientific article published on 26 July 2005

CXCR4-tropic HIV-1 suppresses replication of CCR5-tropic HIV-1 in human lymphoid tissue by selective induction of CC-chemokines

scientific article published on 20 January 2004

Cervico-vaginal tissue ex vivo as a model to study early events in HIV-1 infection

scientific article published on 12 January 2011

Cytomegalovirus-Productive Infection Is Associated With Acute Coronary Syndrome

scientific article published on 20 August 2016

Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1

scientific article published in October 2004

Design and cellular kinetics of dansyl-labeled CADA derivatives with anti-HIV and CD4 receptor down-modulating activity

scientific article

Differential pathogenesis of primary CCR5-using human immunodeficiency virus type 1 isolates in ex vivo human lymphoid tissue

scientific article published in September 2005

Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue

scientific article published in October 2004

Evaluation of the maturation of individual Dengue virions with flow virometry

scientific article published on 16 November 2015

Evidence for the HIV-1 phenotype switch as a causal factor in acquired immunodeficiency.

scientific article published on March 1998

Evidence of perturbations of the cytokine network in preterm labor

scientific article

Evolution of SIV toward RANTES resistance in macaques rapidly progressing to AIDS upon coinfection with HHV-6A.

scientific article published on 2 July 2009

Ex vivo culture of human colorectal tissue for the evaluation of candidate microbicides

scientific article published in June 2006

Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin

scientific article published on 6 February 2012

Flow Virometry to Analyze Antigenic Spectra of Virions and Extracellular Vesicles

scientific article published on 25 January 2017

Flow analysis of individual blood extracellular vesicles in acute coronary syndrome

scientific article published on 5 September 2016

Flow virometry analysis of envelope glycoprotein conformations on individual HIV virions

scientific article published on 19 April 2017

HIV-1 expressing the envelopes of transmitted/founder or control/reference viruses have similar infection patterns of CD4 T-cells in human cervical tissue ex vivo

scientific article

HIV-1 imposes rigidity on blood and semen cytokine networks

scientific article published on 24 September 2012

HIV-1 induced activation of CD4+ T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo

scientific article published in October 2007

HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.

scientific article published on June 2007

HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model.

scientific article

Histocultures (tissue explants) in human retrovirology

scientific article published in January 2014

Human immunodeficiency virus type 1 (HIV-1) non-B subtypes are similar to HIV-1 subtype B in that coreceptor specificity is a determinant of cytopathicity in human lymphoid tissue infected ex vivo

scientific article

Human immunodeficiency virus type 1 coreceptor preferences determine target T-cell depletion and cellular tropism in human lymphoid tissue

scientific article

Human immunodeficiency virus type 1 induces apoptosis in CD4(+) but not in CD8(+) T cells in ex vivo-infected human lymphoid tissue

scientific article

IL-15 alters expression and function of the chemokine receptor CX3CR1 in human NK cells.

scientific article published in August 2004

Immune suppression of human lymphoid tissues and cells in rotating suspension culture and onboard the International Space Station

scientific article published on December 2009

Inhibition of HIV-1 replication in human lymphoid tissues ex vivo by measles virus

scientific article published on 31 May 2005

Interleukin-7 facilitates HIV-1 transmission to cervico-vaginal tissue ex vivo

scientific article

Measles virus vaccine attenuation: suboptimal infection of lymphatic tissue and tropism alteration

scientific article published on 29 June 2007

Modulation of Immune Responses by Extracellular Vesicles From Retinal Pigment Epithelium

scientific article published on August 2016

Multisite comparison of anti-human immunodeficiency virus microbicide activity in explant assays using a novel endpoint analysis

scientific article published on 02 September 2009

Nanoparticle-based flow virometry for the analysis of individual virions

scientific article published on 08 August 2013

Noninfectious X4 but not R5 human immunodeficiency virus type 1 virions inhibit humoral immune responses in human lymphoid tissue ex vivo

scientific article published in July 2004

Pathogenic effects of human herpesvirus 6 in human lymphoid tissue ex vivo

scientific article published in August 2003

Productive HIV-1 infection of human cervical tissue ex vivo is associated with the secretory phase of the menstrual cycle.

scientific article

Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors

scientific article published on 11 October 2010

Rapid induction of anti-idiotypic responses to unmodified monoclonal antibodies from syngeneic mice following primary immunization

scientific article published in February 1993

Real-time PCR assay of individual human immunodeficiency virus type 1 variants in coinfected human lymphoid tissues

scientific article published in May 2003

Revving up Natural Killer Cells and Cytokine-Induced Killer Cells Against Hematological Malignancies

scientific article published on 13 May 2015

Segregation of R5 and X4 HIV-1 variants to memory T cell subsets differentially expressing CD62L in ex vivo infected human lymphoid tissue

scientific article published in June 2002

Selective transmission of R5 HIV-1 variants: where is the gatekeeper?

scientific article

Semen of HIV-1-infected individuals: local shedding of herpesviruses and reprogrammed cytokine network

scientific article published on 22 November 2011

Semen-derived amyloid fibrils drastically enhance HIV infection

scientific article

Small molecule inhibitor of HIV-1 nuclear import suppresses HIV-1 replication in human lymphoid tissue ex vivo: a potential addition to current anti-HIV drug repertoire.

scientific article

Standardization of a cytometric p24-capture bead-assay for the detection of main HIV-1 subtypes

scientific article published on 22 January 2016

Structural differences among monoclonal antibodies with distinct fine specificities and kinetic properties

scientific article published on 01 December 1999

Suppression of CCR5- but not CXCR4-tropic HIV-1 in lymphoid tissue by human herpesvirus 6.

scientific article published on November 2001

Sustained secretion of immunoglobulin by long-lived human tonsil plasma cells.

scientific article published on 9 August 2007

Systematic evaluation of immune regulation and modulation

scientific article published on 21 March 2017

Systemic inflammation and liver damage in HIV/hepatitis C virus coinfection.

scientific article published on 17 May 2016

TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells

article

The cytokine network in women with an asymptomatic short cervix and the risk of preterm delivery.

scientific article published on 6 June 2017

Toxoplasma gondii inhibits R5 HIV-1 replication in human lymphoid tissues ex vivo

scientific article published on 09 August 2009

Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo

scientific article published in March 2008

Use of human tissue explants to study human infectious agents

scientific article

Valacyclovir Decreases Plasma HIV-1 RNA in HSV-2 Seronegative Individuals: A Randomized Placebo-Controlled Crossover Trial

scientific article published on 3 March 2015

Viral interactions in human lymphoid tissue: Human herpesvirus 7 suppresses the replication of CCR5-tropic human immunodeficiency virus type 1 via CD4 modulation

scientific article published on 25 October 2006

Vpr and Vpu are important for efficient human immunodeficiency virus type 1 replication and CD4+ T-cell depletion in human lymphoid tissue ex vivo

scientific article published in November 2004