List of works by Mark R. Davies

A new classifier-based strategy for in-silico ion-channel cardiac drug safety assessment

scientific article

An in silico canine cardiac midmyocardial action potential duration model as a tool for early drug safety assessment.

scientific article published on 23 December 2011

Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing.

scientific article

Capacity limits of asialoglycoprotein receptor-mediated liver targeting

scientific article published on 6 September 2017

Harvesting the promise of AOPs: An assessment and recommendations

scientific article published on 22 February 2018

High-throughput screening of drug-binding dynamics to HERG improves early drug safety assessment

scientific article published on 26 October 2012

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.

scientific article

Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation

scientific article published on 6 June 2017

Nuclear hormone receptor-dependent regulation of hepatic transporters and their role in the adaptive response in cholestasis

scientific article published on 01 July 2008

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

scientific article

Recent developments in using mechanistic cardiac modelling for drug safety evaluation

scientific article

The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue

scientific article published on 23 December 2011

Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment

scientific article

hERG inhibitors with similar potency but different binding kinetics do not pose the same proarrhythmic risk: implications for drug safety assessment

scientific article published on 7 October 2013

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