List of works - Lawrence E Heisler

A comparative analysis of DNA barcode microarray feature size

scientific article

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

scientific article

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

A comprehensive platform for highly multiplexed mammalian functional genetic screens

scientific article

A genome scale overexpression screen to reveal drug activity in human cells

scientific article

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

scientific article

Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor

article

CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β₂-adrenergic receptor

scientific article published on 19 February 2014

Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells

scientific article

Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents

scientific article

Competitive genomic screens of barcoded yeast libraries

scientific article

Compound prioritization methods increase rates of chemical probe discovery in model organisms

scientific article

CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome

scientific article

Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T c

scientific article published on 24 January 2007

Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell.

scientific article

Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation

scientific article

Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

scientific article published in Nature

Functional analysis with a barcoder yeast gene overexpression system

scientific article

Genomic DNA functions as a universal external standard in quantitative real-time PCR

scientific article

Genomic hallmarks of localized, non-indolent prostate cancer.

scientific article published on 9 January 2017

Genotype to phenotype: a complex problem

Scientific article

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.

scientific article published on 09 January 2017

Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples

scientific article

Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics

scientific article

In vitro labeling of gonadal steroid hormone receptors in brain tissue sections

scientific article published on 01 November 1995

Mapping the cellular response to small molecules using chemogenomic fitness signatures

scientific article

Miniature short hairpin RNA screens to characterize antiproliferative drugs

scientific article

Mitochondrial mutations drive prostate cancer aggression

scientific article published on 22 September 2017

Multiple means to the same end: the genetic basis of acquired stress resistance in yeast

scientific article

Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast

scientific article

Prediction of acute myeloid leukaemia risk in healthy individuals

scientific article published in Nature

Progesterone inhibits the estrogen-induced gonadotropin surge in the rhesus monkey independent of endogenous opiates

scientific article published on 01 June 1992

Quantitative phenotyping via deep barcode sequencing.

scientific article

Tracing the origins of relapse in acute myeloid leukaemia to stem cells.

scientific article published on 28 June 2017

Vasopressin mediates hypoglycemia-induced inhibition of luteinizing hormone secretion in the ovariectomized rhesus monkey

Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers

scientific article published on 11 July 2008

List of works by Lawrence E Heisler

A comparative analysis of DNA barcode microarray feature size

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

A comprehensive platform for highly multiplexed mammalian functional genetic screens

A genome scale overexpression screen to reveal drug activity in human cells

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor

CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β₂-adrenergic receptor

Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells

Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents

Competitive genomic screens of barcoded yeast libraries

Compound prioritization methods increase rates of chemical probe discovery in model organisms

CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome

Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T c

Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell.

Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation

Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

Functional analysis with a barcoder yeast gene overexpression system

Genomic DNA functions as a universal external standard in quantitative real-time PCR

Genomic hallmarks of localized, non-indolent prostate cancer.

Genotype to phenotype: a complex problem

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.

Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples

Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics

In vitro labeling of gonadal steroid hormone receptors in brain tissue sections

Mapping the cellular response to small molecules using chemogenomic fitness signatures

Miniature short hairpin RNA screens to characterize antiproliferative drugs

Mitochondrial mutations drive prostate cancer aggression

Multiple means to the same end: the genetic basis of acquired stress resistance in yeast

Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast

Prediction of acute myeloid leukaemia risk in healthy individuals

Progesterone inhibits the estrogen-induced gonadotropin surge in the rhesus monkey independent of endogenous opiates

Quantitative phenotyping via deep barcode sequencing.

Tracing the origins of relapse in acute myeloid leukaemia to stem cells.

Vasopressin mediates hypoglycemia-induced inhibition of luteinizing hormone secretion in the ovariectomized rhesus monkey

Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers