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List of works by Ren-Ke Li

A Conductive Polymer Hydrogel Supports Cell Electrical Signaling and Improves Cardiac Function After Implantation into Myocardial Infarct

scientific article published in August 2015

APPL1 transgenic mice are protected from high-fat diet-induced cardiac dysfunction.

scientific article

Altered expression of disintegrin metalloproteinases and their inhibitor in human dilated cardiomyopathy.

scientific article published on 9 January 2006

Analysis of the upstream regulatory region of human ventricular myosin light chain 1 gene

scientific article (publication date: November 1992)

Angiogenesis by endothelial cell transplantation ⬇️

scientific article published on November 1, 2001

Autologous heart cell transplantation improves cardiac function after myocardial injury

scientific article published on 01 December 1999

Autologous porcine heart cell transplantation improved heart function after a myocardial infarction

scientific article published on 01 January 2000

Back to the bench: The rejuvenation of stem cell therapy--the therapeutic potential of CD133(+) progenitor cells

scientific article published on 18 April 2010

Bcl-2 Engineered MSCs Inhibited Apoptosis and Improved Heart Function

scholarly article by Wenzhong Li et al published August 2007 in Stem Cells

Beneficial effect of autologous cell transplantation on infarcted heart function: comparison between bone marrow stromal cells and heart cells.

scientific article

Bio-stretch, a computerized cell strain apparatus for three-dimensional organotypic cultures

scientific article published on 01 February 1999

Bioactive coating of decellularized vascular grafts with a temperature-sensitive VEGF-conjugated hydrogel accelerates autologous endothelialization in vivo

scientific article published on 30 September 2016

Biodegradable collagen patch with covalently immobilized VEGF for myocardial repair.

scientific article

CD34+ Stem Cells: Promising Roles in Cardiac Repair and Regeneration

scientific article published on 11 June 2019

Canopy 2 attenuates the transition from compensatory hypertrophy to dilated heart failure in hypertrophic cardiomyopathy.

scientific article

Cardiac cell transplantation: closer to bedside.

scientific article

Cardiac myocyte transplantation does not increase global epicardial repolarization heterogeneity in a rat infarct model.

scientific article published on 18 April 2007

Cardiac remodeling and failure From molecules to man (Part II).

scientific article

Cardiac restoration by cell transplantation.

scientific article published in June 2004

Cardiac storage with University of Wisconsin solution and a nucleoside-transport blocker

scientific article published on 01 May 1995

Cardiomyocyte transplantation improves heart function

scientific article published on 01 September 1996

Cardioprotective Signature of Short-Term Caloric Restriction

scientific article

Cardiovascular tissue engineering therapy: so near, so far?

scientific article published in June 2005

Cell transplantation comes of age

scientific article published on 01 May 2001

Cell transplantation for heart disease: the clinical perspective

scientific article published on 01 March 2005

Cell transplantation preserves cardiac function after infarction by infarct stabilization: augmentation by stem cell factor.

scientific article published on 13 October 2005

Cell transplantation preserves matrix homeostasis: a novel paracrine mechanism

scientific article published on 13 October 2005

Cell transplantation to improve ventricular function in the failing heart.

scientific article

Cell transplantation to prevent heart failure: a comparison of cell types.

scientific article

Cell transplantation: back to the bench: introduction

scientific article published on 01 January 2008

Cellular senescence contributes to age-dependent changes in circulating extracellular vesicle cargo and function

scientific article published on 21 January 2020

Cellular, structural and functional cardiac remodelling following pressure overload and unloading.

scientific article published on 23 April 2016

Challenges in allogeneic mesenchymal stem cell-mediated cardiac repair.

scientific article

Chemical syntheses of Trolox conjugates which protect human ventricular myocytes against in situ-generated oxyradicals

scientific article published on 01 December 1993

Class II transactivator knockdown limits major histocompatibility complex II expression, diminishes immune rejection, and improves survival of allogeneic bone marrow stem cells in the infarcted heart.

scientific article published on 24 May 2016

Combined transmyocardial revascularization and cell-based angiogenic gene therapy increases transplanted cell survival

scientific article

Commentary: Circulating factors released after myocardial infarction: Beneficial or detrimental?

scientific article published on 08 November 2018

Comparison of two experimental models for assessment of cardiac preservation

scientific article published on 01 January 1993

Construction of a bioengineered cardiac graft

scientific article published on 01 February 2000

Culture of rat endometrial telocytes.

scientific article published on July 2012

Cultured vascular endothelial cell susceptibility to extracellularly generated oxidant injury.

scientific article

Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress

scientific article

Decreased expression of miR‑9 due to E50K OPTN mutation causes disruption of the expression of BDNF leading to RGC‑5 cell apoptosis

scientific article published on 06 October 2016

Decreasing CNPY2 Expression Diminishes Colorectal Tumor Growth and Development through Activation of p53 Pathway

scientific article published on 30 January 2016

Defining conditions for covalent immobilization of angiogenic growth factors onto scaffolds for tissue engineering.

scientific article published on 17 August 2010

Design and development of a novel biostretch apparatus for tissue engineering

scientific article published on 01 January 2010

Diabetes influences cardiac extracellular matrix remodelling after myocardial infarction and subsequent development of cardiac dysfunction.

scientific article

Diabetic heart dysfunction: is cell transplantation a potential therapy?

scientific article

Differentiation of allogeneic mesenchymal stem cells induces immunogenicity and limits their long-term benefits for myocardial repair ⬇️

scientific article published on November 22, 2010

Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes.

scientific article published on 22 December 2005

Dual roles for bone marrow-derived Sca-1 cells in cardiac function

scientific article published on 23 March 2017

Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction

scientific article published on 09 July 2019

Effect of oxygen tension on the anti-oxidant enzyme activities of tetralogy of Fallot ventricular myocytes

scientific article published on 01 June 1989

Effect of vitamin E on human glutathione peroxidase (GSH-PX1) expression in cardiomyocytes

scientific article published on 01 January 1996

Effects of storage solutions on the viability of human umbilical cord mesenchymal stem cells for transplantation

scientific article

Electrical coupling of isolated cardiomyocyte clusters grown on aligned conductive nanofibrous meshes for their synchronized beating.

scientific article

Enhanced IGF-1 expression improves smooth muscle cell engraftment after cell transplantation

scientific article published on 26 August 2004

Enhanced angiogenesis with multimodal cell-based gene therapy

scientific article

Enhanced cell transplantation: preventing apoptosis increases cell survival and ventricular function

scientific article published on 31 March 2006

Enhanced thoracic gene delivery by magnetic nanobead-mediated vector

scientific article published in August 2008

Evidence for the existence of CD34+ angiogenic stem cells in human first-trimester decidua and their therapeutic for ischaemic heart disease

scientific article published on 08 September 2020

Expression of CNPY2 in mouse tissues: quantification and localization.

scientific article

Fate of modular cardiac tissue constructs in a syngeneic rat model.

scientific article

Feel isolated? Bridging communication between host myocardium and skeletal myoblast grafts

scientific article

Fetal cell transplantation: a comparison of three cell types

scientific article published on 01 October 1999

Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish

scientific article

Fundamentals of reperfusion injury for the clinical cardiologist.

scientific article

Generation of the epicardial lineage from human pluripotent stem cells

scientific article

HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress

scientific article

Heart cell implantation after myocardial infarction.

scientific article

Histologic changes of nonbiodegradable and biodegradable biomaterials used to repair right ventricular heart defects in rats.

scientific article

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias

scientific article published on 02 May 2019

Human pediatric and adult ventricular cardiomyocytes in culture: assessment of phenotypic changes with passaging

scientific article published on 01 August 1996

Hydrogels with integrin-binding angiopoietin-1-derived peptide, QHREDGS, for treatment of acute myocardial infarction.

scientific article published on 28 January 2015

In vivo survival and function of transplanted rat cardiomyocytes

scientific article published on 01 February 1996

Infarct stabilization and cardiac repair with a VEGF-conjugated, injectable hydrogel.

scientific article published on 6 October 2010

Inhibiting matrix metalloproteinase by cell-based timp-3 gene transfer effectively treats acute and chronic ischemic cardiomyopathy.

scientific article published on 23 September 2011

Insulin stimulates pyruvate dehydrogenase and protects human ventricular cardiomyocytes from simulated ischemia

scientific article published in September 1998

Intracardiac injection of matrigel induces stem cell recruitment and improves cardiac functions in a rat myocardial infarction model

scientific article

Intrinsic cardiac stem cells are essential for regeneration

scientific article published on 29 March 2016

Iqcg is essential for sperm flagellum formation in mice

scientific article

Knock-out of MicroRNA 145 impairs cardiac fibroblast function and wound healing post-myocardial infarction

scientific article published on 06 July 2020

Localized SDF-1alpha gene release mediated by collagen substrate induces CD117 stem cells homing

scientific article published on 24 December 2008

Long-term repopulation of aged bone marrow stem cells using young Sca-1 cells promotes aged heart rejuvenation

scientific article published on 05 August 2019

Mast cells promote proliferation and migration and inhibit differentiation of mesenchymal stem cells through PDGF.

scientific article

Maximizing ventricular function with multimodal cell-based gene therapy

scientific article published in August 2005

Mesenchymal stem cells engineered to overexpress stem cell factor improve cardiac function but have malignant potential.

scientific article published on 3 July 2008

Microsomal prostaglandin E2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction

scientific article published on 17 March 2008

Mueller matrix decomposition for polarized light assessment of biological tissues

scientific article

Myocardial salvage with trolox and ascorbic acid for an acute evolving infarction

scientific article published in April 1989

Myometrial cells induce angiogenesis and salvage damaged myocardium.

scientific article published on 16 June 2006

Neonatal transfer of membrane-bound stem cell factor improves survival and heart function in aged mice after myocardial ischemia.

scientific article

Neovascularization derived from cell transplantation in ischemic myocardium.

scientific article

Nr2e1 Downregulation Is Involved in Excess Retinoic Acid-induced Developmental Abnormality in the Mouse Brain

scientific article published on March 2017

Optimal Myocardial Preconditioning in Humansa

scientific article published on 01 June 1999

Optimal conditions for heart cell cryopreservation for transplantation.

scientific article published in January 2003

Optimal time for cardiomyocyte transplantation to maximize myocardial function after left ventricular injury

scientific article published on 01 December 2001

Optimizing cardiac cell therapy: from processing to delivery

scientific article published on 01 October 2005

Overexpression of elastin fragments in infarcted myocardium attenuates scar expansion and heart dysfunction.

scientific article

Phenotypic switching of vascular smooth muscle cells in the 'normal region' of aorta from atherosclerosis patients is regulated by miR-145

scientific article published on 15 March 2016

Polarization birefringence measurements for characterizing the myocardium, including healthy, infarcted, and stem-cell-regenerated tissues

scientific article published in July 2010

Polarized light based birefringence measurements for monitoring myocardial regeneration

Polyethylenimine-mediated gene delivery into human bone marrow mesenchymal stem cells from patients

scientific article published on 13 July 2010

Polypyrrole-chitosan conductive biomaterial synchronizes cardiomyocyte contraction and improves myocardial electrical impulse propagation.

scientific article

Preconditioning human cardiomyocytes and endothelial cells

scientific article published in January 1998

Preservation of heart function in diabetic rats by the combined effects of muscle cell implantation and insulin therapy.

scientific article published on 21 December 2007

Pressure Overload-Induced Cardiac Dysfunction in Aged Male Adiponectin Knockout Mice Is Associated With Autophagy Deficiency.

scientific article published on 11 May 2015

Protective role of Nrf2 against ischemia reperfusion injury and cardiac allograft vasculopathy

scientific article published on 26 November 2019

Quantitative analysis of survival of transplanted smooth muscle cells with real-time polymerase chain reaction.

scientific article published in April 2005

Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1+ stem cells from young donors

scientific article published on 07 February 2020

Reduced ischemic injury after stroke in mice by angiogenic gene delivery via ultrasound-targeted microbubble destruction.

scientific article published in June 2014

Reloading the heart: a new animal model of left ventricular assist device removal

scientific article published in July 2005

Restoration and regeneration of failing myocardium with cell transplantation and tissue engineering.

scientific article published in July 2003

Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells

scientific article published on 4 December 2012

Single nucleotide variances can account for loss of microRNA function: the emerging cross talk between genetics and epigenetics

scientific article published on 01 July 2014

Sirtuin3 protects aged human mesenchymal stem cells against oxidative stress and enhances efficacy of cell therapy for ischaemic heart diseases

scientific article published on 09 August 2018

Skeletal myoblasts preserve remote matrix architecture and global function when implanted early or late after coronary ligation into infarcted or remote myocardium.

scientific article published on September 2008

Smooth muscle cell transplantation into myocardial scar tissue improves heart function

scientific article published on 01 March 1999

Stem cell factor attenuates vascular smooth muscle apoptosis and increases intimal hyperplasia after vascular injury.

scientific article published on 4 January 2007

Stem cell therapy for heart failure: Out with the new and in with the old?

scientific article published on 16 September 2015

Stem cells and regenerative medicine — future perspectives ⬇️

scientific article published on 08 March 2012

Suppression of miR-34a Expression in the Myocardium Protects Against Ischemia-Reperfusion Injury Through SIRT1 Protective Pathway.

scientific article published on 9 June 2017

Synthesis of aliphatic polyester hydrogel for cardiac tissue engineering

scientific article published on 01 January 2014

TIMP-3 deficiency accelerates cardiac remodeling after myocardial infarction.

scientific article

TIMP-3 deficiency leads to dilated cardiomyopathy

scientific article published on 19 July 2004

The cardiac repair benefits of inflammation do not persist: evidence from mast cell implantation

scientific article

The challenges of stem cell therapy

scientific article published on 16 February 2012

The cytoprotective effect of Trolox demonstrated with three types of human cells

scientific article published on 01 October 1990

The effect of age on the efficacy of human mesenchymal stem cell transplantation after a myocardial infarction

scientific article published on 01 August 2010

The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes

scientific article published on 11 January 2014

The limits of cardiac preservation with University of Wisconsin solution

scientific article published on 01 October 1991

The promise and challenges of cardiac stem cell therapy.

scientific article

The rejuvenation of aged stem cells for cardiac repair.

scientific article published on 20 March 2014

The use of MMP2 antibody-conjugated cationic microbubble to target the ischemic myocardium, enhance Timp3 gene transfection and improve cardiac function.

scientific article published on 26 October 2013

Tissue inhibitor of matrix metalloproteinase-3 or vascular endothelial growth factor transfection of aged human mesenchymal stem cells enhances cell therapy after myocardial infarction

scientific article published on 24 September 2012

Tissue-Engineered Grafts Matured in the Right Ventricular Outflow Tract.

scientific article published on March 2004

Tracking cardiac engraftment and distribution of implanted bone marrow cells: Comparing intra-aortic, intravenous, and intramyocardial delivery

scientific article published on 17 March 2009

Transforming the promise of pluripotent stem cell-derived cardiomyocytes to a therapy: challenges and solutions for clinical trials

scientific article

Transplantation of cryopreserved cardiomyocytes

scientific article published on 01 January 2001

Turbid polarimetry for tissue characterization

Two-photon microscopy of healthy, infarcted and stem-cell treated regenerating heart

scientific article published on 08 September 2010

Ultrasound-targeted HSVtk and Timp3 gene delivery for synergistically enhanced antitumor effects in hepatoma.

scientific article published on 19 April 2013

Ultrasound-targeted microbubble destruction in gene therapy: A new tool to cure human diseases

scientific article published on 20 August 2016

Uterine cells are recruited to the infarcted heart and improve cardiac outcomes in female rats

scientific article published on 14 March 2012

Uterine-Derived CD11b Cells Significantly Increase Vasculogenesis and Promote Myocardial Healing in Ischemic Cardiomyopathy.

scientific article published on 30 November 2015

VEGF-loaded microsphere patch for local protein delivery to the ischemic heart

scientific article published on 12 September 2016

Vitamin E and oxidative stress in the heart of the cardiomyopathic syrian hamster

scientific article published on 01 January 1998

Water-soluble antioxidant specificity against free radical injury using cultured human ventricular myocytes and fibroblasts and saphenous vein endothelial cells.

scientific article published in November 1990

Young bone marrow Sca-1 cells protect aged retina from ischaemia-reperfusion injury through activation of FGF2

scientific article published on 25 September 2018

c-Jun N-terminal kinase-mediated stabilization of microsomal prostaglandin E2 synthase-1 mRNA regulates delayed microsomal prostaglandin E2 synthase-1 expression and prostaglandin E2 biosynthesis by cardiomyocytes

scientific article published on 19 April 2006

c-Kit function is necessary for in vitro myogenic differentiation of bone marrow hematopoietic cells.

scientific article published in August 2009

c-kit dysfunction impairs myocardial healing after infarction

scientific article published on 01 September 2007

p27 protein protects metabolically stressed cardiomyocytes from apoptosis by promoting autophagy

scientific article

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