List of works - Randall J. Roper

Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner

scientific article published on 30 December 2014

Clinical identification of feeding and swallowing disorders in 0-6 month old infants with Down syndrome

scientific article published on 27 December 2018

Commonality in Down and fetal alcohol syndromes.

scientific article

Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice

scholarly article

Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model.

scientific article published on 9 January 2016

Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.

scientific article

Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes.

scientific article published in July 2004

Down syndrome mouse models have an abnormal enteric nervous system

scientific article published on 18 April 2019

Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome

scientific article published in June 2010

Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of Down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes

scientific article published on 3 May 2017

Genetic control of susceptibility to experimental Lyme arthritis is polygenic and exhibits consistent linkage to multiple loci on chromosome 5 in four independent mouse crosses.

scientific article

Identification of genetic loci controlling the characteristics and severity of brain and spinal cord lesions in experimental allergic encephalomyelitis.

scientific article published on August 2000

Inferring gene regulatory networks from asynchronous microarray data with AIRnet.

scientific article

Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome

scientific article

Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses

scientific article published on 01 February 1999

Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model

scientific article published on 9 September 2015

Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn.

scientific article

Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome

scientific article published on 10 July 2013

Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic.

scientific article

PCR prescreen for genotyping the Ts65Dn mouse model of Down syndrome

scientific article

Perinatal loss of Ts65Dn Down syndrome mice.

scientific article

Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a

scientific article published on 23 July 2015

Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits.

scientific article published on 20 September 2017

The power of comparative and developmental studies for mouse models of Down syndrome

scientific article

Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice.

scientific article published on 16 September 2011

Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.

scientific article

Understanding the basis for Down syndrome phenotypes

scientific article published in March 2006

List of works by Randall J. Roper

Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner

Clinical identification of feeding and swallowing disorders in 0-6 month old infants with Down syndrome

Commonality in Down and fetal alcohol syndromes.

Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice

Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model.

Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.

Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes.

Down syndrome mouse models have an abnormal enteric nervous system

Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome

Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of Down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes

Genetic control of susceptibility to experimental Lyme arthritis is polygenic and exhibits consistent linkage to multiple loci on chromosome 5 in four independent mouse crosses.

Identification of genetic loci controlling the characteristics and severity of brain and spinal cord lesions in experimental allergic encephalomyelitis.

Inferring gene regulatory networks from asynchronous microarray data with AIRnet.

Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome

Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses

Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model

Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn.

Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome

Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic.

PCR prescreen for genotyping the Ts65Dn mouse model of Down syndrome

Perinatal loss of Ts65Dn Down syndrome mice.

Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a

Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits.

The power of comparative and developmental studies for mouse models of Down syndrome

Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice.

Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.

Understanding the basis for Down syndrome phenotypes