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List of works by Adrian Israelson

A chemical chaperone-based drug candidate is effective in a mouse model of amyotrophic lateral sclerosis (ALS).

scientific article published on 13 March 2015

A photoactivable probe for calcium binding proteins

scientific article published on November 2005

AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS

scientific article published on 01 July 2019

ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import.

scientific article

Assay to Measure Nucleocytoplasmic Transport in Real Time within Motor Neuron-like NSC-34 Cells

scientific article published on 16 May 2017

Azido ruthenium: a new photoreactive probe for calcium-binding proteins

scientific article published on 01 January 2006

Cu/Zn-superoxide dismutase and wild-type like fALS SOD1 mutants produce cytotoxic quantities of H2O2 via cysteine-dependent redox short-circuit

scientific article published on 25 July 2019

Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.

scientific article published on 22 August 2016

Exposure of β6/β7-Loop in Zn/Cu Superoxide Dismutase (SOD1) Is Coupled to Metal Loss and Is Transiently Reversible During Misfolding

scientific article published on 16 December 2020

Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding.

scientific article

In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death

scientific journal article

Localization of the voltage-dependent anion channel-1 Ca2+-binding sites.

scientific article published on 22 August 2006

MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS.

scientific article

Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1.

scientific article

Macrophage migration inhibitory factor as a component of selective vulnerability of motor neurons in ALS.

scientific article published on 17 June 2015

Macrophage migration inhibitory factor: A multifaceted cytokine implicated in multiple neurological diseases.

scientific article

Mapping the ruthenium red-binding site of the voltage-dependent anion channel-1.

scientific article published on 27 June 2007

Misfolded SOD1 Accumulation and Mitochondrial Association Contribute to the Selective Vulnerability of Motor Neurons in Familial ALS: Correlation to Human Disease

scientific article published on 17 July 2017

Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS

scientific article

New fluorescent reagents specific for Ca(2+)-binding proteins

scientific article published on 19 August 2012

Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria

scientific article

Potential roles of gut microbiome and metabolites in modulating ALS in mice

scientific article published on 22 July 2019

Superoxide Dismutase 1 (SOD1)-Derived Peptide Inhibits Amyloid Aggregation of Familial Amyotrophic Lateral Sclerosis SOD1 Mutants.

scientific article published on 19 August 2016

The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins.

scientific article

The voltage-dependent anion channel (VDAC): function in intracellular signalling, cell life and cell death.

scientific article published on January 2006

The voltage-dependent anion channel in endoplasmic/sarcoplasmic reticulum: characterization, modulation and possible function.

scientific article

The voltage-dependent anion channel-1 modulates apoptotic cell death.

scientific article published in July 2005

Why lithium studies for ALS treatment should not be halted prematurely

scientific article published on 2 September 2014

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