List of works - Nikolas K. Haass

A novel mathematical model of heterogeneous cell proliferation

scientific article published in 2021

A quantitative approach to histopathological dissection of elastin-related disorders using multiphoton microscopy.

scientific article published in October 2013

Acetylsalicylic Acid Governs the Effect of Sorafenib in RAS- Mutant Cancers

scientific article

An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells

scientific article published in January 2007

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival

scientific article published on 24 April 2019

Cell Cycle Phase-Specific Drug Resistance as an Escape Mechanism of Melanoma Cells.

scientific article published on 9 March 2016

Cell cycle-tailored targeting of metastatic melanoma: Challenges and opportunities.

scientific article published on 21 January 2017

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine

scientific article published on 14 June 2019

DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.

scientific article published on 05 August 2013

Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha

scientific article published on 29 May 2017

Detection of primary melanoma in individuals at extreme high risk: a prospective 5-year follow-up study

scientific article published on August 2014

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

scientific article

Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo.

scientific article published on 13 March 2018

Erratum: A stress-induced early innate response causes multidrug tolerance in melanoma

article

Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay

scientific article

Examining Go-or-Grow Using Fluorescent Cell-Cycle Indicators and Cell-Cycle-Inhibiting Drugs

scientific article published on 05 February 2020

Expression of Bcl-xL and Mcl-1 in the nonmelanoma skin cancers of renal transplant recipients

scientific article published on April 2015

FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models

scientific article published on 10 August 2018

Fluorescence-Based Quantitative and Spatial Analysis of Tumour Spheroids: A Proposed Tool to Predict Patient-Specific Therapy Response

publication published on 28 May 2021

Friends or foes: IL-10 and TGF-β in melanoma

scientific article published on 01 April 2015

Genetics of basal cell carcinoma.

scientific article published on May 2010

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

scientific article

HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma

scientific article published on 6 December 2017

Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids

scientific article published on 28 December 2015

In vitro three-dimensional tumor microenvironment models for anticancer drug discovery.

scientific article published on January 2008

In vivo overexpression of Emi1 promotes chromosome instability and tumorigenesis.

scientific article published on 11 April 2016

Induction of endoplasmic reticulum stress as a strategy for melanoma therapy: is there a future?

scientific article published on 01 November 2014

JNK-ERK signalling in melanoma: rewired or entangled?

scientific article published in December 2016

Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels.

scientific article published on 23 January 2007

Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma

scientific article published on 21 February 2019

Mathematical Models for Cell Migration with Real-Time Cell Cycle Dynamics

scientific article published in March 2018

Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation

scientific article published on 21 August 2019

Meeting report from the 2011 International Melanoma Congress, Tampa, Florida.

scientific article published on 9 December 2011

Meeting report from the 7th International Melanoma Congress, Sydney, November, 2010.

scientific article published on 22 December 2010

Melanocytes: from morphology to application.

scientific article published on 4 February 2009

Melanoma never says die.

scientific article published on July 2014

Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment

scientific article published on 21 October 2009

Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance.

scientific article

Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.

scientific article

Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer.

scientific article published on 10 November 2016

Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

scientific article

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

scientific article

Persister state-directed transitioning and vulnerability in melanoma

scientific article published on 01 June 2022

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

scientific article published on 03 January 2019

Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma

scientific article

Real-time cell cycle imaging during melanoma growth, invasion, and drug response.

scientific article

Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion

scientific article published in 2022

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.

scientific article published on 5 October 2015

Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage

scientific article

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

scientific article published on 12 June 2017

Targeting glutamine transport to suppress melanoma cell growth.

scientific article published on 17 February 2014

Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy.

scientific article published on 9 April 2014

The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance

scientific article published on 20 October 2012

The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and Metastasis

scientific article published on 06 November 2018

Treosulfan and gemcitabine in metastatic uveal melanoma patients: results of a multicenter feasibility study

scientific article

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB.

scientific article published on 17 May 2016

List of works by Nikolas K. Haass

A novel mathematical model of heterogeneous cell proliferation

A quantitative approach to histopathological dissection of elastin-related disorders using multiphoton microscopy.

Acetylsalicylic Acid Governs the Effect of Sorafenib in RAS- Mutant Cancers

An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival

Cell Cycle Phase-Specific Drug Resistance as an Escape Mechanism of Melanoma Cells.

Cell cycle-tailored targeting of metastatic melanoma: Challenges and opportunities.

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine

DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.

Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha

Detection of primary melanoma in individuals at extreme high risk: a prospective 5-year follow-up study

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo.

Erratum: A stress-induced early innate response causes multidrug tolerance in melanoma

Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay

Examining Go-or-Grow Using Fluorescent Cell-Cycle Indicators and Cell-Cycle-Inhibiting Drugs

Expression of Bcl-xL and Mcl-1 in the nonmelanoma skin cancers of renal transplant recipients

FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models

Fluorescence-Based Quantitative and Spatial Analysis of Tumour Spheroids: A Proposed Tool to Predict Patient-Specific Therapy Response

Friends or foes: IL-10 and TGF-β in melanoma

Genetics of basal cell carcinoma.

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma

Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids

In vitro three-dimensional tumor microenvironment models for anticancer drug discovery.

In vivo overexpression of Emi1 promotes chromosome instability and tumorigenesis.

Induction of endoplasmic reticulum stress as a strategy for melanoma therapy: is there a future?

JNK-ERK signalling in melanoma: rewired or entangled?

Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels.

Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma

Mathematical Models for Cell Migration with Real-Time Cell Cycle Dynamics

Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation

Meeting report from the 2011 International Melanoma Congress, Tampa, Florida.

Meeting report from the 7th International Melanoma Congress, Sydney, November, 2010.

Melanocytes: from morphology to application.

Melanoma never says die.

Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment

Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance.

Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.

Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer.

Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

Persister state-directed transitioning and vulnerability in melanoma

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma

Real-time cell cycle imaging during melanoma growth, invasion, and drug response.

Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.

Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

Targeting glutamine transport to suppress melanoma cell growth.

Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy.

The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance

The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and Metastasis

Treosulfan and gemcitabine in metastatic uveal melanoma patients: results of a multicenter feasibility study

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB.