List of works - Anna E Jonsson

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

scientific article published on 10 May 2017

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets

scientific article

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

scientific article published on 07 July 2009

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults

scientific article published on 17 April 2009

Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies

scientific article

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Clinical risk factors, DNA variants, and the development of type 2 diabetes

scientific article

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

scientific article

Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses

scientific article published on 16 March 2018

Effect of a common variant of the PCSK2 gene on reduced insulin secretion

scientific article published on 26 September 2012

Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans

scientific article published on 4 April 2013

Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

scientific article published on 5 January 2018

FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies

scientific article published on 11 March 2011

GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study

article

Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits

scientific article

Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology

scientific article

Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels

scientific article published on 10 February 2017

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test

scientific article published on 06 January 2021

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study

scientific article published on 27 October 2015

Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

scientific article published on 22 September 2015

Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures

scientific article published on 05 October 2019

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

scientific article

Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk

scientific article

Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins

scientific article published on 21 February 2017

Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

scientific article published on 8 August 2016

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes

scientific article published on 19 February 2009

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Link between GIP and osteopontin in adipose tissue and insulin resistance

scientific article published on 24 January 2013

Maternal and fetal genetic contribution to gestational weight gain.

scientific article published on 9 October 2017

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.

scientific article published on 21 September 2017

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

Obesity, FTO gene variant, and energy intake in children

scientific article published in April 2009

Pleiotropic effects of GIP on islet function involve osteopontin

scientific article

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

scientific article

Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes 2015;64:2513–2525

Role of fasting duration and weekday in incretin and glucose regulation

scientific article published on 01 March 2020

Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes

scientific article

Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB.

scientific article published on 21 November 2017

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets

scientific article published on 27 February 2009

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

scientific article published in September 2008

List of works by Anna E Jonsson

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults

Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Clinical risk factors, DNA variants, and the development of type 2 diabetes

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses

Effect of a common variant of the PCSK2 gene on reduced insulin secretion

Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans

Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies

GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study

Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits

Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology

Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study

Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk

Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins

Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Link between GIP and osteopontin in adipose tissue and insulin resistance

Maternal and fetal genetic contribution to gestational weight gain.

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

Obesity, FTO gene variant, and energy intake in children

Pleiotropic effects of GIP on islet function involve osteopontin

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes 2015;64:2513–2525

Role of fasting duration and weekday in incretin and glucose regulation

Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes

Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB.

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels