List of works - Lotta Agholme

APP-BACE1 Interaction and Intracellular Localization Regulate Aβ Production in iPSC-Derived Cortical Neurons

Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons

scientific article published on 17 January 2020

Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to Lysosomes

scientific article

Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation

scientific article

Amyloid-β secretion, generation, and lysosomal sequestration in response to proteasome inhibition: involvement of autophagy.

scientific article published on January 2012

An in vitro model for neuroscience: differentiation of SH-SY5Y cells into cells with morphological and biochemical characteristics of mature neurons

scientific article published on January 2010

Expression and secretion of synaptic proteins during stem cell differentiation to cortical neurons

scientific article published on 18 October 2018

Getting rid of intracellular Aβ- loss of cellular degradation leads to transfer between connected neurons.

scientific article published on January 2014

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection

scientific article published on 01 July 2020

Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons

scientific article published on January 2010

Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease

scientific article published on 16 May 2010

Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric Aβ.

scientific article published on 2 November 2017

Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease

scientific article published on 08 October 2013

Partial reduction of amyloid β production by β-secretase inhibitors does not decrease synaptic transmission

scientific article published on 26 May 2020

Proteasome inhibition induces stress kinase dependent transport deficits--implications for Alzheimer's disease

scientific article published on 21 November 2013

Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance

scientific article published on 9 January 2014

Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid.

scientific article published in June 2012

Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17β-estradiol

Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage

scientific article published on 02 March 2020

List of works by Lotta Agholme

APP-BACE1 Interaction and Intracellular Localization Regulate Aβ Production in iPSC-Derived Cortical Neurons

Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons

Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to Lysosomes

Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation

Amyloid-β secretion, generation, and lysosomal sequestration in response to proteasome inhibition: involvement of autophagy.

An in vitro model for neuroscience: differentiation of SH-SY5Y cells into cells with morphological and biochemical characteristics of mature neurons

Expression and secretion of synaptic proteins during stem cell differentiation to cortical neurons

Getting rid of intracellular Aβ- loss of cellular degradation leads to transfer between connected neurons.

Guidelines for the use and interpretation of assays for monitoring autophagy

HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection

Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons

Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease

Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric Aβ.

Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease

Partial reduction of amyloid β production by β-secretase inhibitors does not decrease synaptic transmission

Proteasome inhibition induces stress kinase dependent transport deficits--implications for Alzheimer's disease

Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance

Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid.

Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17β-estradiol

Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage