List of works by Gautam Sethi

'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling.

scientific article

6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways.

scientific article

A brief update on potential molecular mechanisms underlying antimicrobial and wound-healing potency of snake venom molecules.

scientific article published on 11 March 2016

A facile assay to monitor secretory phospholipase A₂ using 8-anilino-1-naphthalenesulfonic acid.

scientific article published on 7 June 2014

A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade

scientific article published on 24 November 2016

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

scientific article published on 12 January 2017

A novel combinatorial strategy using Seliciclib(®) and Belinostat(®) for eradication of non-small cell lung cancer via apoptosis induction and BID activation

scientific article published on 23 July 2016

A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells

scientific article published on March 2006

ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and c-Myc to reduce breast cancer proliferation

scientific article published on 20 April 2016

Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics

scientific article

Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model.

scientific article published on 3 May 2014

Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma.

scientific article

Activation of c-Jun N-terminal kinase is required for ultraviolet B-induced apoptosis of murine peritoneal macrophages in vitro

scientific article published in February 2004

Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs

scientific article published on 10 December 2015

Ageing and the telomere connection: An intimate relationship with inflammation

scientific article

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.

scientific article published on October 2013

Analysis of the intricate relationship between chronic inflammation and cancer.

scientific article published on May 2015

Animal venoms as antimicrobial agents.

scientific article published on 10 March 2017

Annexin-A1 controls an ERK-RhoA-NFκB activation loop in breast cancer cells.

scientific article published on 9 April 2015

Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.

scientific article

Anti-Inflammatory activity of Angelica keiskei through suppression of mitogen-activated protein kinases and nuclear factor-kappaB activation pathways.

scientific article

Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives

scientific article

Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway.

scientific article published on 14 June 2011

Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development

scientific article

Artesunate suppresses tumor growth and induces apoptosis through the modulation of multiple oncogenic cascades in a chronic myeloid leukemia xenograft mouse model

scientific article published on February 2015

Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

scientific article published on 07 October 2016

Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.

scientific article

Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.

scientific article published in July 2008

Bergamottin, a natural furanocoumarin obtained from grapefruit juice induces chemosensitization and apoptosis through the inhibition of STAT3 signaling pathway in tumor cells

scientific article published on 14 August 2014

Bioactive natural products in cancer prevention and therapy: Progress and promise

scientific article published on 23 August 2016

Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential

scientific article published on 01 April 2019

Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel

scientific article published on March 2015

Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4.

scientific article published on 20 March 2017

Butein and Its Role in Chronic Diseases.

scientific article published on January 2016

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells.

scientific article published on 10 August 2010

Butein in health and disease: A comprehensive review

scientific article published on 12 December 2016

Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue

scientific article published on 17 April 2007

Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds.

scientific article published on 30 March 2016

Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases

scientific article published on 11 December 2013

Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer

scientific article

Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer

scientific article published on 29 November 2016

Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade

scientific article published on 05 December 2018

Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells.

scientific article published on November 2011

Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo

scientific article published on 27 February 2012

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation

scientific article published on April 2007

Cellular Uptake of Ginsenosides in Korean White Ginseng and Red Ginseng and Their Apoptotic Activities in Human Breast Cancer Cells ⬇️

scientific article published on July 28, 2010

Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cells

scientific article (publication date: 12 October 2016)

Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5α-reductase and extracellular signal-regulated kinase

scientific article

Combined use of irinotecan with histone deacetylase inhibitor belinostat could cause severe toxicity by inhibiting SN-38 glucuronidation via UGT1A1.

scientific article

Conditioned media from adipocytes promote proliferation, migration, and invasion in melanoma and colorectal cancer cells

scientific article published on 09 March 2019

Corilagin in Cancer: A Critical Evaluation of Anticancer Activities and Molecular Mechanisms

scientific article published on 19 September 2019

Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model

scientific article published on April 2009

Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cance

scientific article published on March 2007

Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.

scientific article published on 23 May 2007

Curcumin: getting back to the roots.

scientific article

DEAD-box helicase DP103 defines metastatic potential of human breast cancers

scientific article

Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases

scientific article published in October 2007

Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action

scientific article

Design and synthesis of benzimidazole-based Rho kinase inhibitors for the treatment of glaucoma

scientific article published on 4 October 2017

Development of Novel Triazolo-Thiadiazoles from Heterogeneous "Green" Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors

scientific article

Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo

scientific article

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.

scientific article

Do STAT3 inhibitors have potential in the future for cancer therapy?

scientific article

Dual role of autophagy in hallmarks of cancer.

scientific article published on 19 December 2017

Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.

scientific article published on 9 August 2012

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

scientific article published on October 2013

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

scientific article

Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha

scientific article published on 28 May 2007

Epidermal growth factor (EGF) activates nuclear factor-κB through IκBα kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IκBα.

scientific article

Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages

scientific article published on 10 July 2007

Exosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from Immunosurveillance

scientific article

Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: association with smokeless tobacco.

scientific article published on June 2007

Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway.

scientific article

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.

scientific article

Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells

scientific article published on 9 February 2016

Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances ap

scientific article

From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer.

scientific article

Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - experimental validation in human breast and colon cancer

scientific article published on 29 June 2016

Functionalized tetrahydro-1H-pyrido[4,3-b]indoles: a novel chemotype with Sirtuin 2 inhibitory activity

scientific article published on 18 December 2014

Gamma Radiation-Induced Disruption of Cellular Junctions in HUVECs Is Mediated through Affecting MAPK/NF-κB Inflammatory Pathways

scientific article published on 04 August 2019

Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.

scientific article

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers.

scientific article published on March 2015

Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma

scientific article published on 26 June 2013

Garcinol: Current status of its anti-oxidative, anti-inflammatory and anti-cancer effects.

scientific article published on 18 March 2015

Gene Microarray Analyses of Daboia russelli russelli Daboiatoxin Treatment of THP-1 Human Macrophages Infected with Burkholderia pseudomallei.

scientific article published on 22 November 2015

Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.

scientific article

Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase.

scientific article published on 13 February 2017

Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products. ⬇️

scientific article published on 30 March 2007

Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1.

scientific article

Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway

scientific article published on 01 September 2006

Identification of a novel Calotropis procera protein that can suppress tumor growth in breast cancer through the suppression of NF-κB pathway

scientific article

Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.

scientific article published on 8 April 2010

Identification of natural peptides as a new class of antimalarial drugs by in silico approaches

scientific article published on January 2017

Identification of novel peroxisome proliferator-activated receptor-gamma (PPARγ) agonists using molecular modeling method.

scientific article

In vitro activation of murine peritoneal macrophages by ultraviolet B radiation: upregulation of CD18, production of NO, proinflammatory cytokines and a signal transduction pathway.

scientific article published on April 2004

Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway.

scientific article published on 19 June 2006

Inflammation and cancer: how hot is the link?

scientific article published on 4 August 2006

Influenza A virus enhances its propagation through the modulation of Annexin-A1 dependent endosomal trafficking and apoptosis.

scientific article published on 04 March 2016

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model

scientific article published on 20 July 2011

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

scientific article

Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model

scientific article published on 26 October 2015

Involvement of MAP kinase signal transduction pathway in UVB-induced activation of macrophages in vitro.

scientific article published in December 2003

Involvement of fas/fas ligand in ultraviolet B-induced apoptosis of murine peritoneal macrophages.

scientific article published in January 2004

Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer.

scientific article

Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.

scientific article

Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades.

scientific article

Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives

scientific article

Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer.

scientific article published on 27 July 2012

LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway

scientific article published on 23 December 2020

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases

scientific article published on 16 March 2019

Melioidosis: Clinical impact and public health threat in the tropics.

retracted scientific article

Mending the bones with natural products.

scientific article published in July 2007

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

scientific article published on 18 November 2017

Molecular Targets of Ascochlorin and Its Derivatives for Cancer Therapy

scientific article

Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements

scientific article published on 12 February 2020

Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer.

scientific article published on 17 December 2010

Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis

scientific article published on April 2007

N'-Alkylaminosulfonyl Analogues of 6-Fluorobenzylideneindolinones with Desirable Physicochemical Profiles and Potent Growth Inhibitory Activities on Hepatocellular Carcinoma.

scientific article

NF-κB in cancer therapy.

scientific article

Natural bioactives and phytochemicals serve in cancer treatment and prevention.

scientific article published on 19 December 2013

Natural bioactives in cancer treatment and prevention

scientific article

Natural products as a gold mine for arthritis treatment.

scientific article published on May 2007

Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.

scientific article

Neuronal Development-Related miRNAs as Biomarkers for Alzheimer's disease, Depression, Schizophrenia and Ionizing Radiation Exposure

scientific article published on 21 January 2020

Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model.

scientific article published on 9 December 2015

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

scientific article

Novel medicines and strategies in cancer treatment and prevention

scientific article

Novel phospholipase A2 inhibitors from python serum are potent peptide antibiotics.

scientific article published on 9 January 2015

Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo

scientific article

Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma

scientific article

Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

scientific article

Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives.

scientific article

Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: preclinical and clinical evidence.

scientific article published on 30 January 2014

Oleuropein induces apoptosis via abrogating NF-κB activation cascade in estrogen receptor-negative breast cancer cells

scientific article published on 27 September 2018

Ophiopogonin D modulates multiple oncogenic signaling pathways, leading to suppression of proliferation and chemosensitization of human lung cancer cells.

scientific article

Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway

scientific article

PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple Negative Breast Cancers

scientific article published on 15 August 2017

Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling

scientific article published on 3 January 2018

Phytometabolites Targeting the Warburg Effect in Cancer Cells: A Mechanistic Review

scientific article published on April 2016

Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.

scientific article

Plant-based hydrocarbon esters from Tragia involucrata possess antimicrobial and anti-inflammatory activities.

scientific article published on April 2013

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

scientific article

Polo-like kinase inhibitors: an emerging opportunity for cancer therapeutics.

scientific article published on January 2010

Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-AT

scientific article

Potential Benefits of Edible Berries in the Management of Aerodigestive and Gastrointestinal Tract Cancers: Preclinical and Clinical Evidence.

scientific article published on 17 March 2015

Potential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators.

scientific article

Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer.

scientific article published on 12 July 2017

Potential of neem (Azadirachta indica L.) for prevention and treatment of oncologic diseases

scientific article published on 24 March 2016

Potential role of targeted therapies in the treatment of triple-negative breast cancer.

scientific article published on 17 December 2015

Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-kappaB and MAPK signalling

scientific article

Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells.

scientific article published on 27 February 2016

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.

scientific article published on 12 December 2006

Retraction notice to "Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines" [Biochem. Pharmacol. 73 (2007) 1024

scientific article published on 20 February 2016

SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation

scientific article

SREBP-1c as a molecular bridge between lipogenesis and cell cycle progression of clear cell renal carcinoma.

scientific article published on 14 November 2017

Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review.

scientific article

Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products.

scientific article published on March 2014

Simvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, suppresses osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand through modulation of NF-kappaB pathway.

scientific article

Snake venom phospholipases A(2): a novel tool against bacterial diseases.

scientific article published on January 2012

Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo

scientific article published on 03 December 2010

Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production

scientific article

TNF-alpha-induced mitochondrial alterations in human T cells requires FADD and caspase-8 activation but not RIP and caspase-3 activation

scientific article

TNF: a master switch for inflammation to cancer

scientific article published on May 2008

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer.

scientific article published on 17 August 2013

Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer

scientific article published on 07 March 2012

Targeting TNF for Treatment of Cancer and Autoimmunity

scientific article published on January 2009

Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy

scientific article published on 07 April 2015

Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention.

scientific article published on 23 September 2017

Targeting arachidonic acid pathway by natural products for cancer prevention and therapy.

scientific article published on 4 February 2016

Targeting autophagy using natural compounds for cancer prevention and therapy

scientific article published on 12 February 2019

Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer.

scientific article published on January 2011

Targeting multiple oncogenic pathways for the treatment of hepatocellular carcinoma

scientific article

Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.

scientific article

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution

scientific article

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

scientific article published on 21 November 2015

Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.

scientific article

Targeting transcription factor NF-kappaB to overcome chemoresistance and radioresistance in cancer therapy.

scientific article published on 14 January 2010

Targeting transcription factor STAT3 for cancer prevention and therapy.

scientific article

The Role of Resveratrol in Cancer Therapy.

scientific article published in December 2017

The butanol fraction of guava (Psidium cattleianum Sabine) leaf extract suppresses MMP-2 and MMP-9 expression and activity through the suppression of the ERK1/2 MAPK signaling pathway

scientific article

The multifaceted role of curcumin in cancer prevention and treatment.

scientific article

The multifaceted role of reactive oxygen species in tumorigenesis

scientific article published on 01 May 2020

The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy

scientific article published on 01 December 2020

The potential role of boswellic acids in cancer prevention and treatment.

scientific article published on 14 April 2016

The role of hydrogen sulfide in cyclic nucleotide signaling.

scientific article published on 17 November 2017

The vascular endothelium and human diseases

scientific article

The vital role of ATP citrate lyase in chronic diseases

scientific article published on 19 December 2019

Therapeutic implications of toll-like receptors in peripheral neuropathic pain

scientific article published on 25 November 2016

Therapeutic potential of gambogic acid, a caged xanthone, to target cancer

scientific article published on 12 December 2017

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

scientific article

Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROS

scientific article (publication date: 2013)

Thymoquinone: potential cure for inflammatory disorders and cancer

scientific article published on 10 October 2011

Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics.

scientific article published on 5 August 2017

Traditional Chinese Medicine in Neuroprotection after Brain Insults with Special Reference to Radioprotection

article

Triple negative breast cancer in Asia: An insider's view

scientific article published on 10 November 2017

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway

scientific article

Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies.

scientific article published on 13 March 2013

Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells

scientific article

Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways

scientific article

Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells

scientific article published on 3 August 2017

Viperatoxin-II: A novel viper venom protein as an effective bactericidal agent.

scientific article published on 23 October 2015

Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.

scientific article published on 25 January 2017

Wound healing activity and mechanisms of action of an antibacterial protein from the venom of the eastern diamondback rattlesnake (Crotalus adamanteus)

scientific article

Zyflamend, a polyherbal preparation, inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of NF-kappa B activation and NF-kappa B-regulated gene products

scientific article published on 01 January 2007

β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase.

scientific article published on 13 June 2013

β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

scientific article published on 26 August 2011

β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through down-modulation of NF-κB-regulated gene products

scientific article published on April 2014

Paulina is supported by:

About Paulina

Help