List of works - Alberto Bresciani

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

scientific article published in June 2023

A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins.

scientific article

Aspergillus olivimuriae sp. nov., a halotolerant species isolated from olive brine

scientific article published in September 2019

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin

scientific article published on 2 September 2015

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters

scientific article published on 04 July 2019

Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni

scientific article

Development of a Broadly Applicable Assay for Measurement of Glycan-Directed Enzymatic Activity

scientific article published on 22 June 2018

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems

scientific article

Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.

scientific article published on 6 October 2017

Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro

scientific article published on 22 October 2018

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs

scientific article published on 5 March 2016

Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy

scientific article published on 12 October 2020

Fish-derived antimicrobial peptides: Activity of a chionodracine mutant against bacterial models and human bacterial pathogens

scientific article published on 18 February 2019

Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening

scientific article published on 26 November 2018

Identification by High-Throughput Screening of Pseudomonas Acyl–Coenzyme A Synthetase Inhibitors

scientific article published on 31 January 2017

Identification of a series of 4-[3-(quinolin-2-yl)-1,2,4-oxadiazol-5-yl]piperazinyl ureas as potent smoothened antagonist hedgehog pathway inhibitors.

scientific article published on 14 July 2011

Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

scientific article published on 27 December 2018

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides

scientific article published on 27 November 2018

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease

scientific article published on 06 May 2019

Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors

scientific article published on 24 March 2020

N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists

scientific article published on 14 July 2011

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).

scientific article published on 8 August 2017

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

scientific article

Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis

scientific article published on 23 June 2011

Quantifying autophagy using novel LC3B and p62 TR-FRET assays.

scientific article published on 19 March 2018

Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome

scientific article published on 19 September 2017

List of works by Alberto Bresciani

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins.

Aspergillus olivimuriae sp. nov., a halotolerant species isolated from olive brine

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters

Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni

Development of a Broadly Applicable Assay for Measurement of Glycan-Directed Enzymatic Activity

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems

Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.

Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs

Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy

Fish-derived antimicrobial peptides: Activity of a chionodracine mutant against bacterial models and human bacterial pathogens

Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening

Identification by High-Throughput Screening of Pseudomonas Acyl–Coenzyme A Synthetase Inhibitors

Identification of a series of 4-[3-(quinolin-2-yl)-1,2,4-oxadiazol-5-yl]piperazinyl ureas as potent smoothened antagonist hedgehog pathway inhibitors.

Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease

Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors

N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis

Quantifying autophagy using novel LC3B and p62 TR-FRET assays.

Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome