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List of works by Hauke Busch

'Moving genes': how dystonia genes functionally converge on the transcriptome

scientific article published on 01 September 2020

(MIF) Drives Murine Psoriasiform Dermatitis

A Comprehensive Molecular Characterization of the Pancreatic Neuroendocrine Tumor Cell Lines BON-1 and QGP-1

scientific article published on 14 March 2020

A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.

scientific article

A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice ⬇️

scientific article published on 13 May 2019

A Numerical Aggregation Algorithm for the Enzyme-Catalyzed Substrate Conversion

ABA-Induced Vegetative Diaspore Formation in

scientific article published in 2019

Absence of the Integrin α3 Subunit Induces an Activated Phenotype in Human Keratinocytes

scientific article published on 03 February 2017

Abstract 2284: Dissecting signaling networks involved in the tumor-microenvironment crosstalk in chronic lymphocytic leukemia (CLL)

Ambrisentan, an endothelin receptor type A-selective antagonist, inhibits cancer cell migration, invasion, and metastasis

scientific article published on 28 September 2020

An integrated personal and population-based Egyptian genome reference

scientific article published on 18 September 2020

B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells

scientific article

BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines

scientific article published on 12 January 2018

Bid Expression Network Controls Neuronal Cell Fate During Avian Ciliary Ganglion Development.

scientific article published on 29 June 2018

Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression

scientific article published on 17 April 2017

Biodiversity of mycobial communities in health and onychomycosis

scientific article published on 25 May 2022

Boolean Modeling Reveals the Necessity of Transcriptional Regulation for Bistability in PC12 Cell Differentiation

scientific article published on 14 April 2016

Boolean approach to signalling pathway modelling in HGF-induced keratinocyte migration

scientific article

CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia.

scientific article published on 5 May 2016

Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

scientific article published on 19 June 2018

Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling

scientific article

Complement Receptor 1 (CR1, CD35) Polymorphisms and Soluble CR1: A Proposed Anti-inflammatory Role to Quench the Fire of "Fogo Selvagem" Pemphigus Foliaceus

scientific article published on 22 November 2019

Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization

scientific article published on 30 May 2013

Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7.

scientific article published on 7 December 2017

Constitutional absence of epithelial integrin α3 impacts the composition of the cellular microenvironment of ILNEB keratinocytes

article

Cover Image, Volume 9, Issue 4

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation

scientific article published on 05 December 2018

Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.

scientific article published on 10 December 2012

Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration

scientific article published on 28 December 2018

Dietary ursolic acid improves health span and life span in male Drosophila melanogaster

scientific article published on 29 November 2018

Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals

scientific article published on 4 April 2018

Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.

scientific article

ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer

scientific article

Effect of colored noise on networks of nonlinear oscillators

scientific article published on 16 July 2001

Epithelioid hemangioendotheliomas of the liver and lung in children and adolescents.

scientific article

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

scientific article published on 01 April 2018

Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response.

scientific article published on 22 June 2018

Gene network dynamics controlling keratinocyte migration

scientific article published on July 2008

Genetic Associations and Differential mRNA Expression Levels of Host Genes Suggest a Viral Trigger for Endemic Pemphigus Foliaceus

scientific article published on 23 April 2022

Genetic variability of immune-related lncRNAs: polymorphisms in linc-pint and LY86-AS1 are associated with pemphigus foliaceus susceptibility

scientific article published on 04 January 2021

Genetics and Omics Analysis of Autoimmune Skin Blistering Diseases

scientific article published on 15 October 2019

Genome-wide association study of psoriasis in an Egyptian population

scientific article published on 01 May 2019

Global gene expression profiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines

scientific article

Global remodelling of cellular microenvironment due to loss of collagen VII.

scientific article published on 16 April 2013

HSPB3 protein is expressed in motoneurons and induces their survival after lesion-induced degeneration

scientific article published on 24 August 2016

Host plant diet affects growth and induces altered gene expression and microbiome composition in the wood white (Leptidea sinapis) butterfly

scientific article published on 20 November 2020

IL-17A is functionally relevant and a potential therapeutic target in bullous pemphigoid

scientific article published on 13 September 2018

Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma.

scientific article published on 5 April 2018

Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

scientific article published in Nature Communications

Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation

scientific article

IgG Fc sialylation is regulated during the germinal center reaction upon immunization with different adjuvants

scientific article published on 20 May 2020

Image-derived models of cell organization changes during differentiation and drug treatments

scientific article published on 27 November 2019

Immunoglobulin G of systemic sclerosis patients programs a pro-inflammatory and profibrotic phenotype in monocyte-like THP-1 cells

scientific article published on 23 November 2020

In silico approaches and the role of ontologies in aging research

scientific article

In silico candidate variant and gene identification using inbred mouse strains

scientific article published on 11 March 2021

Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation.

scientific article published on 31 March 2014

Induction of phenotype modifying cytokines by FERMT1 mutations.

scientific article published in March 2011

Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways

scientific article published on 07 January 2019

Influence of spatiotemporal 1/ f α−noise on structure formation in excitable media

Influence of spatiotemporally correlated noise on structure formation in excitable media

scientific article published on 25 April 2003

Information Theoretic Concepts to Unravel Cell–Cell Communication

Integration of activating and inhibitory receptor signaling by regulated phosphorylation of Vav1 in immune cells

scientific article published on 31 May 2011

Integrative genomic and transcriptomic analysis in plasmablastic lymphoma identifies disruption of key regulatory pathways

scientific article published on 01 January 2022

Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity

scientific article published on 19 October 2020

Label-free detection of neuronal differentiation in cell populations using high-throughput live-cell imaging of PC12 cells

scientific article

Lithocholic Acid Improves the Survival of Drosophila Melanogaster

scientific article published on 03 September 2018

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

scientific article published on 26 November 2020

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.

scientific article published on 12 April 2018

MMP14 empowers tumor-initiating breast cancer cells under hypoxic nutrient-depleted conditions

scientific article published on 06 December 2018

Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan

scientific article published on 13 July 2019

Maternally inherited differences within mitochondrial Complex I control murine healthspan

article published in 2018

Method for detecting the signature of noise-induced structures in spatiotemporal data sets

scientific article

Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks

article

Monoallelic Mutations in the Translation Initiation Codon of KLHL24 Cause Skin Fragility

scientific journal article

Network theory inspired analysis of time-resolved expression data reveals key players guiding P. patens stem cell development

scientific article

New tools for analyzing noise-induced phenomena in biological oscillators

Noise-memory induced excitability and pattern formation in oscillatory neural models

scientific article published on 22 February 2006

Nurse-like cells show deregulated expression of genes involved in immunocompetence.

scientific article published on 25 May 2011

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

scientific article published in February 2018

One-year surveillance of SARS-CoV-2 transmission of the ELISA cohort: A model for population-based monitoring of infection risk

scientific article published on 15 April 2022

Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL

scientific article published on 12 July 2019

Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides

scientific article published on 9 April 2018

Personalized Clinical Decision Making Through Implementation of a Molecular Tumor Board: A German Single-Center Experience

scientific article published on 16 August 2018

Polymorphisms in the Mitochondrial Genome Are Associated With Bullous Pemphigoid in Germans

scientific article published on 22 November 2019

Protein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation

scientific article published on 24 January 2017

Proteolysis-a characteristic of tumor-initiating cells in murine metastatic breast cancer

scientific article published on 16 August 2016

Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts

scientific article

Qtlizer: comprehensive QTL annotation of GWAS results

scientific article published on 24 November 2020

RARβ regulates neuronal cell death and differentiation in the avian ciliary ganglion

scientific article published on 7 February 2015

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

scientific article published on 19 December 2017

Requirements Analysis and Specification for a Molecular Tumor Board Platform Based on cBioPortal

scientific article published on 10 February 2020

Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles.

scientific article published on 26 April 2018

S100A6 Regulates Endothelial Cell Cycle Progression by Attenuating Antiproliferative Signal Transducers and Activators of Transcription 1 Signaling

scientific article published on 7 July 2016

SNAIL1 employs β-Catenin-LEF1 complexes to control colorectal cancer cell invasion and proliferation

scientific article published on 18 September 2019

SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells.

scientific article published on 20 November 2017

STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.

scientific article published on 5 August 2013

Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine

scientific article published on January 2015

Sequential Treatment With Targeted and Immune Checkpoint Therapy in Patients With BRAF Positive Metastatic Melanoma: The Importance of Timing?

scientific article published on 17 December 2019

Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling

scientific article published on 5 February 2018

Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study

scientific article published on 9 August 2017

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

scientific article published on 12 February 2018

Specific role of RhoC in tumor invasion and metastasis

scientific article published on 16 September 2017

Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors

scientific article

Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency

scientific article published on 18 June 2020

Systems Biology

TGFβ-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC

scientific article published on 21 May 2019

Targeting of apoptotic pathways by SMAC or BH3 mimetics distinctly sensitizes paclitaxel-resistant triple negative breast cancer cells.

scientific article published on 6 February 2017

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

scientific article published on 17 April 2017

The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints

scientific article published on 21 October 2013

The use of urinary proteomics in the assessment of suitability of mouse models for ageing

scientific article

Understanding the mTOR signaling pathway via mathematical modeling

scientific article published on 10 February 2017

mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

scientific article

miR-149 Suppresses Breast Cancer Metastasis by Blocking Paracrine Interactions with Macrophages

scientific article published on 07 January 2020

miR-181 elevates Akt signaling by co-targeting PHLPP2 and INPP4B phosphatases in luminal breast cancer.

scientific article

miR149 functions as a tumor suppressor by controlling breast epithelial cell migration and invasion

scientific article

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