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List of works by Narin Osman

Androgens: new effects on proteoglycan biosynthesis and its consequences for atherosclerosis.

scientific article published in July 2005

Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle

scientific article

Endothelin-1 actions on vascular smooth muscle cell functions as a target for the prevention of atherosclerosis.

scientific article

Endothelin-1 stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by endothelin receptor transactivation of the transforming growth factor-[beta] type I receptor.

scientific article published on October 2010

Enzymatic remodelling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis.

scientific article

Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response.

scientific article

Flavopiridol inhibits TGF-β-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2.

scientific article published on 9 February 2018

G protein coupled receptor transactivation: extending the paradigm to include serine/threonine kinase receptors.

scientific article published on 02 February 2012

Gaq proteins: molecular pharmacology and therapeutic potential.

scientific article published on 4 November 2016

Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFβ receptor phosphorylation.

scientific article

Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation.

scientific article

Individual Smad2 linker region phosphorylation sites determine the expression of proteoglycan and glycosaminoglycan synthesizing genes

scientific article published on 10 November 2018

Mechanisms of PAR-1 mediated kinase receptor transactivation: Smad linker region phosphorylation

scientific article published on 09 July 2019

Mouse macrophage beta subunit (CD11b) cDNA for the CR3 complement receptor/Mac-1 antigen

scientific article published in January 1990

Multiple Growth Factors, But Not VEGF, Stimulate Glycosaminoglycan Hyperelongation in Retinal Choroidal Endothelial Cells.

scientific article published on 18 July 2016

Peptidyl-prolyl isomerases: functionality and potential therapeutic targets in cardiovascular disease

scientific article

Physical association of CD5 and the T cell receptor/CD3 antigen complex on the surface of human T lymphocytes ⬇️

scientific article published on 01 May 1993

Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes.

scientific article published on 5 November 2015

RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells.

scientific article published on 18 July 2017

Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis.

scientific article published on 15 February 2018

Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans

scientific article published on 21 September 2012

Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells.

scientific article

TGF-beta stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2.

scientific article published on 7 March 2010

TGF-β stimulates biglycan core protein synthesis but not glycosaminoglycan chain elongation via Akt phosphorylation in vascular smooth muscle.

scientific article published in October 2011

The expansion of GPCR transactivation-dependent signalling to include serine/threonine kinase receptors represents a new cell signalling frontier.

scientific article

The human FCG1 gene encoding the high-affinity Fc gamma RI maps to chromosome 1q21

scientific article published on 01 January 1993

The protein interactions of the immunoglobulin receptor family tyrosine-based activation motifs present in the T cell receptor zeta subunits and the CD3 gamma, delta and epsilon chains

scientific article published on 01 May 1996

The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle.

scientific article

The role of tyrosine phosphorylation in the interaction of cellular tyrosine kinases with the T cell receptor ζ chain tyrosine‐based activation motif ⬇️

scientific article published on 01 October 1995

Therapeutic implications of endothelin and thrombin G-protein-coupled receptor transactivation of tyrosine and serine/threonine kinase cell surface receptors.

scientific article published on 20 August 2012

Thrombin promotes PAI-1 expression and migration in keratinocytes via ERK dependent Smad linker region phosphorylation.

scientific article

Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells.

scientific article published on 14 October 2014

Transforming growth factor-β regulation of proteoglycan synthesis in vascular smooth muscle: contribution to lipid binding and accelerated atherosclerosis in diabetes.

scientific article published on December 2010

Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation.

scientific article published on 11 June 2013

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