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List of works by Torsten Goldmann

A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy

scientific article published on 14 June 2007

A receptor-type protein tyrosine phosphatase PTP zeta is expressed in human cutaneous melanomas

scientific article published in January 2000

A reduced TKI dosage is not associated with loss of activity in EGFR mutated NSCLC patients

scientific article published on 9 September 2014

A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18.

scientific article published on 13 January 2006

AI (artificial intelligence) in histopathology--from image analysis to automated diagnosis

scientific article published on January 2009

Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers

scientific article published on 06 August 2018

Alveolar epithelial cells type II are major target cells for C. pneumoniae in chronic but not in acute respiratory infection.

scientific article published on July 2004

Alveolar macrophages are the main source for tumour necrosis factor-alpha in patients with sarcoidosis

scientific article published in March 2003

Animal shed Bacillus licheniformis spores possess allergy-protective as well as inflammatory properties

scientific article published on 25 June 2008

Antiviral CD8+ T-cell immune responses are impaired by cigarette smoke and in COPD

scientific article published in 2023

Budesonide Inhibits Intracellular Infection with Non-Typeable Haemophilus influenzae Despite Its Anti-Inflammatory Effects in Respiratory Cells and Human Lung Tissue: A Role for p38 MAP Kinase

scientific article published on 10 October 2015

CCR2 and CXCR3 agonistic chemokines are differently expressed and regulated in human alveolar epithelial cells type II.

scientific article

CXCR7 transcription in human non-small cell lung cancer and tumor-free lung tissues; possible regulation upon chemotherapy.

scientific article published in March 2008

Comment on Nietner et al. [Virchows Arch (s2012) 461:259-269].

scientific article published on 20 July 2013

Comparison of the effect of LPS and PAM3 on ventilated lungs

scientific article

Correction: Hydroxyethyl Starch (HES 130/0.4) Impairs Intestinal Barrier Integrity and Metabolic Function: Findings from a Mouse Model of the Isolated Perfused Small Intestine

scientific article published on 23 April 2015

Correction: effect of low tidal ventilation on lung function and inflammation in mice.

scientific article published on 23 February 2012

Correlation of EGFR expression, gene copy number and clinicopathological status in NSCLC.

scientific article

Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits.

scientific article published on 16 June 2017

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

scientific article published on 01 August 2018

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

scientific article published on 27 October 2016

DNA methylation markers of surfactant proteins in lung cancer

scientific article

Dexamethasone and N-acetyl-cysteine attenuate Pseudomonas aeruginosa-induced mucus expression in human airways.

scientific article

Diagnostic value of immunohistochemically detected surfactant—apoprotein-A in malignant tumors located in the lungs: Report of two cases

scientific article published on 01 April 2001

Differential Haemoglobin Gene Expression in the Crustacean Daphnia magna Exposed to Different Oxygen Partial Pressures

article

Direct and indirect in situ PCR.

scientific article published in January 2003

Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease

scientific article published on 08 February 2007

Downregulation of the TGFβ Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.

scientific article

Effect of dexamethasone and ACC on bacteria-induced mucin expression in human airway mucosa

scientific article

Effect of low tidal volume ventilation on lung function and inflammation in mice

scientific article

Effect of steroids, acetyl-cysteine and calcium-activated chloride channel inhibitors on allergic mucin expression in sinus mucosa.

scientific article published in September 2008

Effects of antimicrobial peptides on methanogenic archaea.

scientific article

Effects of the CXCR2 antagonist AZD5069 on lung neutrophil recruitment in asthma

scientific article published on 23 May 2017

Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation.

scientific article published on 26 August 2012

Enhanced molecular analyses by combination of the HOPE-technique and laser microdissection

scientific article published on 31 March 2006

Epigenetic modifications of the VGF gene in human non-small cell lung cancer tissues pave the way towards enhanced expression

scientific article published on 28 November 2017

Epigenetic modifications of the immune-checkpoint genes CTLA4 and PDCD1 in non-small cell lung cancer results in increased expression

scientific article published on 11 May 2017

Epipodite and fat cells as sites of hemoglobin synthesis in the branchiopod crustacean Daphnia magna.

scientific article published in November 1999

Exploration of the sputum methylome and omics deconvolution by quadratic programming in molecular profiling of asthma and COPD: the road to sputum omics 2.0.

scientific article published on 19 October 2020

Expression analysis of EML4 in normal lung tissue and non-small cell lung cancer (NSCLC) in the absence and presence of chemotherapeutics.

scientific article published on January 2010

Expression of the CTL2 transcript variants in human peripheral blood cells and human tissues.

scientific article published on 11 March 2013

Expression of the acute phase protein haptoglobin in human lung cancer and tumor-free lung tissues.

scientific article

Facilities of a novel tissue fixation method: the HOPE-technology

Fountain of youth for squamous cell carcinomas? On the epigenetic age of non-small cell lung cancer and corresponding tumor-free lung tissues

scientific article published on 16 October 2018

Functional Toll-Like Receptor 9 Expression and CXCR3 Ligand Release in Pulmonary Sarcoidosis

scientific article

Gene Network Analysis of Interstitial Macrophages After Treatment with Induced Pluripotent Stem Cells Secretome (iPSC-cm) in the Bleomycin Injured Rat Lung.

scientific article published on 18 December 2017

Generation and evaluation of a monoclonal antibody, designated MAdL, as a new specific marker for adenocarcinomas of the lung ⬇️

scientific article published on August 2, 2011

Glioma infiltration of the corpus callosum: early signs detected by DTI

scientific article published on 24 January 2013

HMGA2 overexpression in non-small cell lung cancer.

scientific article

HOPE fixation of cytospin preparations of human cells for in situ hybridization and immunocytochemistry

scientific article

HOPE fixation: a novel fixing method and paraffin-embedding technique for human soft tissues.

scientific article published in January 2001

HOPE technique enables Western blot analysis from paraffin-embedded tissues.

scientific article published on January 2004

HOPE--a new fixing technique enables preservation and extraction of high molecular weight DNA and RNA of > 20 kb from paraffin-embedded tissues. Hepes-Glutamic acid buffer mediated Organic solvent Protection Effect.

scientific article published in January 2002

HOPE--a novel tool for the pathologist.

scientific article

HOPE-BAL: improved molecular diagnostics by application of a novel technique for fixation and paraffin embedding

scientific article

HOPE-fixation enables improved PCR-based detection and differentiation of Mycobacterium tuberculosis complex in paraffin-embedded tissues.

scientific article published on January 2003

HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies

scientific article

HOPE-preservation of paraffin-embedded sputum samples--a new way of bioprofiling in COPD.

scientific article

High-throughput DNA methylation profiling using universal bead arrays

scientific article

Human alveolar epithelial cells induce nitric oxide synthase-2 expression in alveolar macrophages

scientific article published in April 2002

Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis

scientific article published on 24 July 2018

Human lung cancer cells express functionally active Toll-like receptor 9

scientific article

Human lung tissue explants reveal novel interactions during Legionella pneumophila infections.

scientific article published on 28 October 2013

Hydroxyethyl starch (HES 130/0.4) impairs intestinal barrier integrity and metabolic function: findings from a mouse model of the isolated perfused small intestine

scientific article

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development

scientific article

Identification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease

article

Image standards in tissue-based diagnosis (diagnostic surgical pathology)

scientific article

Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?

scientific article published on 28 July 2015

Improved molecular read-out options via adequate tissue fixation

Inhibition of Lipopolysaccharide- and Lipoprotein-Induced Inflammation by Antitoxin Peptide Pep19-2.5.

scientific article published on 26 July 2018

Innate immunity in the human lung: pathogen recognition and lung disease

scientific article published on 09 October 2010

Inter-laboratory validation of PCR-based detection of Mycobacterium tuberculosis in formalin-fixed, paraffin-embedded tissues

scientific article published on 21 June 2005

Interleukin-18 expression by alveolar epithelial cells type II in tuberculosis and sarcoidosis

scientific article published on February 2006

Interleukin-1β provided by KIT-competent mast cells is required for -mutant lung adenocarcinoma

scientific article published on 11 April 2019

IκB Kinase α Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma

scientific article published on 27 March 2018

LED-FISH: Fluorescence microscopy based on light emitting diodes for the molecular analysis of Her-2/neu oncogene amplification

scientific article

LPS-induced mucin expression in human sinus mucosa can be attenuated by hCLCA inhibitors.

scientific article

Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication

scientific article

Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP.

scientific article published on March 2010

Lipid Analysis of Airway Epithelial Cells for Studying Respiratory Diseases

scientific article

Lipidomes of lung cancer and tumour-free lung tissues reveal distinct molecular signatures for cancer differentiation, age, inflammation, and pulmonary emphysema

scientific article published on 11 September 2017

Lipopolysaccharide interaction is decisive for the activity of the antimicrobial peptide NK-2 against Escherichia coli and Proteus mirabilis

scientific article

Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides

scientific article

Live and let die: epigenetic modifications of Survivin and Regucalcin in non-small cell lung cancer tissues contribute to malignancy

scientific article published on 12 November 2019

Localization of ceramide and glucosylceramide in human epidermis by immunogold electron microscopy.

scientific article

Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa

scientific article published in February 2005

Measuring Immune Responses In Situ

article

Meat allergy associated with galactosyl-α-(1,3)-galactose (α-Gal)-Closing diagnostic gaps by anti-α-Gal IgE immune profiling

scientific article published on 3 July 2017

Mechanisms of cilia-driven transport in the airways in the absence of mucus

scientific article published on July 2014

Modulation of the Inflammatory Response toStreptococcus pneumoniaein a Model of Acute Lung Tissue Infection

scientific article published on 15 May 2008

Molecular characterisation of kappa-5, a major antigenic glycoprotein from Schistosoma mansoni eggs.

scientific article published on 20 February 2009

Molecular high throughput analyses and automated detection systems

Monoclonal antibody S60-4-14 reveals diagnostic potential in the identification of Pseudomonas aeruginosa in lung tissues of cystic fibrosis patients.

scientific article

Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes.

scientific article published on 16 April 2009

Multi-analyte profiling of inflammatory mediators in COPD sputum--the effects of processing

scientific article published on 15 November 2014

Multiple peptide resistance factor (MprF)-mediated Resistance of Staphylococcus aureus against antimicrobial peptides coincides with a modulated peptide interaction with artificial membranes comprising lysyl-phosphatidylglycerol.

scientific article published on 7 April 2011

Mycobacteria Induce IFN- Production in Human Dendritic Cells via Triggering of TLR2

scientific article published on 01 May 2006

Mycobacteria infect different cell types in the human lung and cause species dependent cellular changes in infected cells

scientific article published on 23 January 2016

Natural killer cell-mediated rejection of experimental human lung cancer by genetic overexpression of major histocompatibility complex class I chain-related gene A.

scientific article

Neutrophil Extracellular Trap Formation is regulated by CXCR2 in COPD neutrophils

scientific article published on 15 February 2018

Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients

scientific article published on 22 August 2015

Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1β - A Possible Pathway of Exacerbations in COPD

scientific article

Nontypeable Haemophilus influenzae (NTHi) directly interfere with the regulation of E-cadherin in lung epithelial cells

scientific article published on 09 August 2017

On the significance of Surfactant Protein-A within the human lungs

scientific article published on 12 March 2009

Optimized immunohistochemistry in combination with image analysis: a reliable alternative to quantitative ELISA determination of uPA and PAI-1 for routine risk group discrimination in breast cancer.

scientific article published on 16 January 2013

P2Y6 Receptor Activation Promotes Inflammation and Tissue Remodeling in Pulmonary Fibrosis.

scientific article published on 22 August 2017

PD-L1 copy number gain in nonsmall-cell lung cancer defines a new subset of patients for anti PD-L1 therapy

scientific article published on 20 October 2015

Papers should spell out authors' roles

scientific article published on 01 June 1999

Pathology on the edge of interdisciplinarity. A historical epitome.

scientific article published on January 2011

Peptide drug stability: The anti-inflammatory drugs Pep19-2.5 and Pep19-4LF in cream formulation

scientific article published on 11 January 2018

Phenotype and genotype associations of lung carcinoma with atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa.

scientific article published in January 2005

Phosphoinositide 3-OH kinase inhibition prevents ventilation-induced lung cell activation.

scientific article published on 24 October 2003

PilY1 Promotes Legionella pneumophila Infection of Human Lung Tissue Explants and Contributes to Bacterial Adhesion, Host Cell Invasion, and Twitching Motility. ⬇️

scientific article published on 7 March 2017

Preclinical investigations reveal the broad-spectrum neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors

scientific article published on 14 January 2013

Preselection of EGFR mutations in non-small-cell lung cancer patients by immunohistochemistry: comparison with DNA-sequencing, EGFR wild-type expression, gene copy number gain and clinicopathological data

article

Prognostic Classification of Malignant Melanomas by Combining Clinical, Histological, and Immunohistochemical Parameters

scientific article published on 01 April 1999

Progressive paralysis caused by radiation-induced cervical malignant peripheral nerve sheath tumor

scientific article

Proteomics out of the archive: Two-dimensional electrophoresis and mass spectrometry using HOPE-fixed, paraffin-embedded tissues.

scientific article

Proteomics?

scientific article published on 01 March 2012

Pulmonale Infektionen im humanen Lungengewebsmodell

scientific article published on 01 June 2005

Pulmonary haptoglobin (pHp) is part of the surfactant system in the human lung.

scientific article

Pulmonary haptoglobin: a new marker for adenocarcinomas of the lung?

scientific article published on 01 January 2011

Pulmonary responses to overventilation in late multiple organ failure

scientific article published in December 2006

Quinidine, but not eicosanoid antagonists or dexamethasone, protect the gut from platelet activating factor-induced vasoconstriction, edema and paralysis

scientific article

Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against Gram-negative pathogens

scientific article published on 27 March 2007

Roasting and lipid binding provide allergenic and proteolytic stability to the peanut allergen Ara h 8

scientific article published on 01 February 2014

S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection

scientific article

Signalling mechanisms in PAF-induced intestinal failure.

scientific article published on 17 October 2017

Stretch activates nitric oxide production in pulmonary vascular endothelial cells in situ

scientific article published on 28 August 2003

Structural Analysis of the Capsular Polysaccharide fromAcinetobacter lwoffiiF78

Structure and mode of action of the antimicrobial peptide arenicin

scientific article

TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens

scientific article published on 12 August 2008

Texture- and object-related automated information analysis in histological still images of various organs.

scientific article published in December 2008

The HOPE technique opens up a multitude of new possibilities in pathology.

scientific article published on January 2006

The HOPE-technique permits Northern blot and microarray analyses in paraffin-embedded tissues.

scientific article published in January 2004

The Multi-Modal Effect of the Anti-fibrotic Drug Pirfenidone on NSCLC

scientific article published on 01 January 2019

The TGF-beta-pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae.

scientific article

The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

scientific article

The effect of dithiothreitol on the transcriptome of induced sputum cells.

scientific article published on 9 April 2013

The expression of proteolytic enzymes at the dermal invading front of primary cutaneous melanoma predicts metastasis

scientific article published on 01 January 1999

The human placenta releases substances that drive lung cancer into apoptosis

scientific article published on 21 August 2009

The impact of heated tobacco products on arterial stiffness

scientific article published on 28 July 2020

The prognostic value of the expression of collagenase IV, cathepsin D and metallothionein in squamous cell carcinomas of the skin determined by immunohistochemistry

scientific article published on 01 March 2001

The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease.

scientific article

The tissue is the issue: improved methylome analysis from paraffin-embedded tissues by application of the HOPE technique

scientific article

Theory of sampling and its application in tissue based diagnosis.

scientific article published on 16 February 2009

Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis

scientific article

Tissue microarrays from HOPE-fixed specimens allow for enhanced high throughput molecular analyses in paraffin-embedded material.

scientific article

To be at the right place at the right time ⬇️

scientific article published on July 22, 2011

Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients

scientific article

Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung

scientific article published on 18 January 2003

Transforming growth factor-beta signaling leads to uPA/PAI-1 activation and metastasis: a study on human breast cancer tissues.

scientific article

Transkriptionelle Aktivität der Surfactant-Apoproteine A1 und A2 in nicht kleinzelligen Bronchialkarzinomen und tumorfreien Lungengeweben

scientific article published on 01 June 2004

Transparent polyamide: a promising new material for microscopic slides

scientific article published on 01 January 1998

Triggering receptor expressed on myeloid cells-1 (Trem-1) on blood neutrophils is associated with cytokine inducibility in human E. coli sepsis

scientific article published on 15 February 2013

Tumor characteristics involved in the metastatic behaviour as an improvement in primary cutaneous melanoma prognostics

scientific article published on 01 December 1998

Tumors in the lung--morphologic features and the challenge of integrating biomarker signatures into diagnostics.

scientific article published on January 2010

Virtual slides in peer reviewed, open access medical publication.

scientific article published on 19 December 2011

What's cooking? detection of important biomarkers in HOPE-fixed, paraffin-embedded tissues eliminates the need for antigen retrieval.

scientific article

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