List of works - Marta Massanella

A case cluster demonstrating the relationship between HLA concordance and virologic and disease outcomes in human immunodeficiency virus infection.

scientific article

A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity.

scientific article published on 24 May 2011

Adenosine deaminase enhances the immunogenicity of human dendritic cells from healthy and HIV-infected individuals

scientific article

Analyses of Mitochondrial DNA and Immune Phenotyping Suggest Accelerated T-Cell Turnover in Treated HIV

article

Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells

article

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes

scientific article published on 16 July 2016

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

scientific article published on 12 April 2019

Assessing main death pathways in T lymphocytes from HIV infected individuals.

scientific article

Attacking the HIV reservoir from the immune and viral perspective

scientific article published on March 2013

Brief Report: Effect of CMV and HIV Transcription on CD57 and PD-1 T-Cell Expression During Suppressive ART.

scientific article published on 25 January 2016

Brief Report: Impaired CD4 T-Cell Response to Autophagy in Treated HIV-1-Infected Individuals.

scientific article

CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART

scientific article published on 01 April 2010

Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection

scientific article published on October 2015

Changes in T-cell subsets in HIV-HCV-coinfected patients during pegylated interferon-alpha2a plus ribavirin treatment

scientific article published in January 2010

Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection

scientific article published on 24 January 2022

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

scientific article

Continuous prophylactic ARV/ART since birth reduces seeding and persistence of the viral reservoir in vertically HIV-infected children

scientific article published on 05 June 2020

Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment.

scientific article

Deep molecular characterization of HIV-1 dynamics under suppressive HAART

scientific article

Different plasma markers of inflammation are influenced by immune recovery and cART composition or intensification in treated HIV infected individuals

scientific article

Differential gene expression in HIV-infected individuals following ART.

scientific article published on 06 August 2013

Dynamics of CD8 T-cell activation after discontinuation of HIV treatment intensification

scientific article published in June 2013

Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy.

scientific article published on 14 May 2013

Elevated humoral response to cytomegalovirus in HIV-infected individuals with poor CD4+ T-cell immune recovery.

scientific article published on 21 September 2017

Evaluation of the Aptima HIV-1 Quant Dx Assay for HIV-1 RNA Quantitation in Different Biological Specimen Types

scientific article published on 7 June 2017

Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection

scientific article

HIV exposed seronegative individuals show antibodies specifically recognizing native HIV envelope glycoprotein

scientific article published on June 2013

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4.

scientific article

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.

scientific article published on 14 March 2010

Immunodiscordant responses to HAART--mechanisms and consequences

scientific article

Improved assays to measure and characterize the inducible HIV reservoir

scientific article published on 11 October 2018

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid

scientific article published on 15 May 2020

Increased ex vivo cell death of central memory CD4 T cells in treated HIV infected individuals with unsatisfactory immune recovery

scientific article published on 17 July 2015

Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise

scientific article published on 17 January 2018

Influence of the ARV regimen on the early changes in plasma HIV RNA and immune activation at initiation of antiretroviral therapy in naïve HIV-1-infected patients

scientific article published on 17 December 2020

Infrequent HIV Infection of Circulating Monocytes during Antiretroviral Therapy

scientific article published on 12 December 2019

Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection

scientific article published on January 2014

Lack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.

scientific article published on 02 August 2016

Measuring the latent reservoir in vivo.

scientific article published on February 2016

Memory B cell dysregulation in HIV-1-infected individuals.

scientific article published on 2 November 2017

Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy.

scientific article

Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique

scientific article published on 7 September 2017

Nadir CD4 T Cell Count as Predictor and High CD4 T Cell Intrinsic Apoptosis as Final Mechanism of Poor CD4 T Cell Recovery in Virologically Suppressed HIV‐Infected Patients: Clinical Implications

article

On the steps of cell-to-cell HIV transmission between CD4 T cells

scientific article

Preserved immune functionality and high CMV-specific T-cell responses in HIV-infected individuals with poor CD4+ T-cell immune recovery

scientific article published on 15 September 2017

Quantification of HIV RNA and Human Herpesvirus DNA in Seminal Plasma

scientific article published on May 2015

Quantification of Total and 2-LTR (Long terminal repeat) HIV DNA, HIV RNA and Herpesvirus DNA in PBMCs ⬇️

scientific article

Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery

scientific article published on November 2012

Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV

article

Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection.

scientific article published on 3 February 2016

Residual inflammation and viral reservoirs: alliance against an HIV cure

scientific article

Restricted infection of xenotropic murine leukemia virus-related virus in human lymphoid tissue

scientific article published on 6 June 2011

Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome

scientific article published on 20 March 2013

Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals

scientific article

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

article

Standard vaccines increase HIV-1 transcription during antiretroviral therapy.

scientific article published on 16 July 2016

Subclinical Cytomegalovirus DNA Is Associated with CD4 T Cell Activation and Impaired CD8 T Cell CD107a Expression in People Living with HIV despite Early Antiretroviral Therapy

scientific article published on 14 June 2019

Susceptibility of human lymphoid tissue cultured ex vivo to xenotropic murine leukemia virus-related virus (XMRV) infection

scientific article

TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses

scientific article published on 11 November 2020

The Sordid Affair Between Human Herpesvirus and HIV

scientific article

The effect of cell subset isolation method on gene expression in leukocytes.

scientific article published on 20 September 2013

The reconstitution of the thymus in immunosuppressed individuals restores CD4-specific cellular and humoral immune responses

scientific article published on 19 April 2011

Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study.

scientific article published on 28 September 2011

Viremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and function

scientific article (publication date: 2012)

List of works by Marta Massanella

A case cluster demonstrating the relationship between HLA concordance and virologic and disease outcomes in human immunodeficiency virus infection.

A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity.

Adenosine deaminase enhances the immunogenicity of human dendritic cells from healthy and HIV-infected individuals

Analyses of Mitochondrial DNA and Immune Phenotyping Suggest Accelerated T-Cell Turnover in Treated HIV

Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

Assessing main death pathways in T lymphocytes from HIV infected individuals.

Attacking the HIV reservoir from the immune and viral perspective

Brief Report: Effect of CMV and HIV Transcription on CD57 and PD-1 T-Cell Expression During Suppressive ART.

Brief Report: Impaired CD4 T-Cell Response to Autophagy in Treated HIV-1-Infected Individuals.

CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART

Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection

Changes in T-cell subsets in HIV-HCV-coinfected patients during pegylated interferon-alpha2a plus ribavirin treatment

Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

Continuous prophylactic ARV/ART since birth reduces seeding and persistence of the viral reservoir in vertically HIV-infected children

Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment.

Deep molecular characterization of HIV-1 dynamics under suppressive HAART

Different plasma markers of inflammation are influenced by immune recovery and cART composition or intensification in treated HIV infected individuals

Differential gene expression in HIV-infected individuals following ART.

Dynamics of CD8 T-cell activation after discontinuation of HIV treatment intensification

Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy.

Elevated humoral response to cytomegalovirus in HIV-infected individuals with poor CD4+ T-cell immune recovery.

Evaluation of the Aptima HIV-1 Quant Dx Assay for HIV-1 RNA Quantitation in Different Biological Specimen Types

Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection

HIV exposed seronegative individuals show antibodies specifically recognizing native HIV envelope glycoprotein

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4.

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.

Immunodiscordant responses to HAART--mechanisms and consequences

Improved assays to measure and characterize the inducible HIV reservoir

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid

Increased ex vivo cell death of central memory CD4 T cells in treated HIV infected individuals with unsatisfactory immune recovery

Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise

Influence of the ARV regimen on the early changes in plasma HIV RNA and immune activation at initiation of antiretroviral therapy in naïve HIV-1-infected patients

Infrequent HIV Infection of Circulating Monocytes during Antiretroviral Therapy

Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection

Lack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.

Measuring the latent reservoir in vivo.

Memory B cell dysregulation in HIV-1-infected individuals.

Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy.

Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique

Nadir CD4 T Cell Count as Predictor and High CD4 T Cell Intrinsic Apoptosis as Final Mechanism of Poor CD4 T Cell Recovery in Virologically Suppressed HIV‐Infected Patients: Clinical Implications

On the steps of cell-to-cell HIV transmission between CD4 T cells

Preserved immune functionality and high CMV-specific T-cell responses in HIV-infected individuals with poor CD4+ T-cell immune recovery

Quantification of HIV RNA and Human Herpesvirus DNA in Seminal Plasma

Quantification of Total and 2-LTR (Long terminal repeat) HIV DNA, HIV RNA and Herpesvirus DNA in PBMCs ⬇️

Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery

Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV

Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection.

Residual inflammation and viral reservoirs: alliance against an HIV cure

Restricted infection of xenotropic murine leukemia virus-related virus in human lymphoid tissue

Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome

Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

Standard vaccines increase HIV-1 transcription during antiretroviral therapy.

Subclinical Cytomegalovirus DNA Is Associated with CD4 T Cell Activation and Impaired CD8 T Cell CD107a Expression in People Living with HIV despite Early Antiretroviral Therapy

Susceptibility of human lymphoid tissue cultured ex vivo to xenotropic murine leukemia virus-related virus (XMRV) infection

TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses

The Sordid Affair Between Human Herpesvirus and HIV

The effect of cell subset isolation method on gene expression in leukocytes.

The reconstitution of the thymus in immunosuppressed individuals restores CD4-specific cellular and humoral immune responses

Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study.

Viremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and function