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List of works by Naomi Kiyota

3D Culture Represents Apoptosis Induced by Trastuzumab Better than 2D Monolayer Culture.

scientific article published in May 2018

A Multicenter Phase II Trial of Docetaxel, Cisplatin, and Cetuximab (TPEx) Followed by Cetuximab and Concurrent Radiotherapy for Patients With Local Advanced Squamous Cell Carcinoma of the Head and Neck (CSPOR HN01: ECRIPS Study)

A Phase II study of the safety and efficacy of lenvatinib in patients with advanced thyroid cancer

scientific article published on 14 January 2019

A phase I study of sorafenib in combination with S-1 plus cisplatin in patients with advanced gastric cancer

scientific article published on 27 March 2013

A phase I study of tasisulam sodium using an albumin-tailored dose in Japanese patients with advanced solid tumors

scientific article

A prospective study on the efficacy of two-dose influenza vaccinations in cancer patients receiving chemotherapy

scientific article published on 13 March 2016

A prospective, multicenter phase I/II study of induction chemotherapy with docetaxel, cisplatin and fluorouracil (DCF) followed by chemoradiotherapy in patients with unresectable locally advanced esophageal carcinoma.

scientific article published on 18 May 2016

A randomized, open-label, Phase III clinical trial of nivolumab vs. therapy of investigator's choice in recurrent squamous cell carcinoma of the head and neck: A subanalysis of Asian patients versus the global population in checkmate 141.

scientific article published in September 2017

A review of head and neck cancer staging system in the TNM classification of malignant tumors (eighth edition)

scientific article published on 01 July 2019

Adapalene Gel 0.1% Versus Placebo as Prophylaxis for Anti-Epidermal Growth Factor Receptor-Induced Acne-Like Rash: A Randomized Left-Right Comparative Evaluation (APPEARANCE)

scientific article published on 19 March 2019

Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin

scientific article published on 03 September 2018

Adjuvant treatment for post-operative head and neck squamous cell carcinoma.

scientific article

Afatinib vs Placebo as Adjuvant Therapy After Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck: A Randomized Clinical Trial

scientific article published on 13 June 2019

Altered fractionation radiotherapy combined with concurrent low-dose or high-dose cisplatin in head and neck cancer: A systematic review of literature and meta-analysis

scientific article published on 8 December 2017

CheckMate 141: 1-Year Update and Subgroup Analysis of Nivolumab as First-Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer

scientific article published on 04 June 2018

Clinical impact of cachexia in unresectable locally advanced head and neck cancer: supplementary analysis of a phase II trial (JCOG0706-S2)

scientific article published on 01 January 2019

Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer

scientific article

Concomitant chemoradiotherapy for advanced squamous cell carcinoma of the temporal bone.

scientific article published on 20 May 2015

Control of Lung Metastases and Colon Polyposis with Lenvatinib Therapy in a Patient with Cribriform-Morular Variant of Papillary Thyroid Carcinoma and an APC Gene Mutation: A Case Study

scientific article published on 25 September 2019

Controversies in relation to neck management in N0 early oral tongue cancer

scientific article published on 01 April 2019

Defining Radioiodine-Refractory Differentiated Thyroid Cancer: Efficacy and Safety of Lenvatinib by Radioiodine-Refractory Criteria in the SELECT Trial.

scientific article published on 30 June 2017

Discontinuation of sorafenib can lead to the emergence of FLT3-ITD-positive acute myeloid leukemia

Distribution of erlotinib in rash and normal skin in cancer patients receiving erlotinib visualized by matrix assisted laser desorption/ionization mass spectrometry imaging.

scientific article

Effects of aprepitant on the pharmacokinetics of controlled-release oral oxycodone in cancer patients

scientific article

Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line

scientific article published on 9 April 2013

Exploratory analysis of biomarkers associated with clinical outcomes from the study of lenvatinib in differentiated cancer of the thyroid.

scientific article published on 23 February 2017

Exploratory analysis of prognostic factors for lenvatinib in radioiodine-refractory differentiated thyroid cancer

scientific article published on 23 April 2019

Expression of programmed death-1 (PD-1) in sentinel lymph nodes of breast cancer

scientific article published on 01 October 2017

Expression of programmed death-1 in sentinel lymph nodes of breast cancer.

scientific article published on 28 November 2017

FDG-PET/contrast-enhanced CT as a post-treatment tool in head and neck squamous cell carcinoma: comparison with FDG-PET/non-contrast-enhanced CT and contrast-enhanced CT.

scientific article published on 19 July 2015

Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks

scientific article published on 8 June 2011

Hypothyroidism in patients with colorectal carcinoma treated with fluoropyrimidines.

scientific article published on 30 July 2013

Ibuprofen gargle for chemo- or Chemoradiotherapy-induced Oral Mucositis: a feasibility study

scientific article published on 01 June 2020

Impact of retropharyngeal lymph node dissection in the surgical treatment of hypopharyngeal cancer

scientific article published on 08 January 2019

Influence of cure of Helicobacter pylori infection on gastric acidity and gastroesophageal reflux: study by 24-h pH monitoring in patients with gastric or duodenal ulcer.

scientific article published in April 2005

Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification

scientific article published on 17 May 2012

International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV

scientific article published on 12 January 2019

Japanese Clinical Practice Guideline for Head and Neck Cancer

scientific article published on 18 March 2017

Left atrial extension of metastatic lung tumor via pulmonary vein: report on the first case of Ewing sarcoma.

scientific article published on 30 September 2010

Lenvatinib for Anaplastic Thyroid Cancer.

scientific article published on March 2017

Lenvatinib versus placebo in radioiodine-refractory thyroid cancer.

scientific article published in February 2015

Long-term survival of a patient with metastatic melanoma treated with nivolumab and vemurafenib, with the development of vitiligo

scientific article published on 01 April 2017

Low-Dose vs. High-Dose Cisplatin: Lessons Learned From 59 Chemoradiotherapy Trials in Head and Neck Cancer

scientific article published on 21 February 2019

Management of axitinib (AG-013736)-induced fatigue and thyroid dysfunction, and predictive biomarkers of axitinib exposure: results from phase I studies in Japanese patients.

scientific article

Measuring quality of life in patients with head and neck cancer: Update of the EORTC QLQ-H&N Module, Phase III.

scientific article published on 15 May 2014

Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line.

scientific article

Mediastinal Germ Cell Tumor Exhibiting a Discrepancy between Tumor Markers and Imaging: A Case Study.

scientific article published on May 2015

Metabolomics evaluation of serum markers for cachexia and their intra-day variation in patients with advanced pancreatic cancer

scientific article

Modified TALK Score for Japanese Patients with Laryngeal and Hypopharyngeal Cancers to Predict the Possibility of Laryngeal Preservation by Concurrent Chemoradiotherapy

Multicenter Phase 2 Study of Cisplatin and 5-Fluorouracil With Concurrent Radiation Therapy as an Organ Preservation Approach in Patients With Squamous Cell Carcinoma of the Cervical Esophagus

scientific article

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

scientific article published on 8 October 2016

Nivolumab versus investigator's choice in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: Efficacy and safety in CheckMate 141 by age

scientific article published on 03 July 2019

Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141): health-related quality-of-life results from a randomised, phase 3 trial.

scientific article

Nivolumab vs investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck: 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expression

scientific article published on 17 April 2018

Nonplatinum-based chemotherapy with irinotecan plus docetaxel for advanced or metastatic olfactory neuroblastoma: a retrospective analysis of 12 cases.

scientific article

Nutritional support dependence after curative chemoradiotherapy in head and neck cancer: supplementary analysis of a phase II trial (JCOG0706S1)

scientific article published in December 2019

Optimal use of lenvatinib in the treatment of advanced thyroid cancer.

scientific article published on 24 October 2017

Pharmacokinetic study of the oral fluorouracil antitumor agent S-1 in patients with impaired renal function.

scientific article published on 11 May 2019

Phase I dose-escalating study of panobinostat (LBH589) administered intravenously to Japanese patients with advanced solid tumors

scientific article

Phase I trial of combination chemotherapy with docetaxel, cisplatin and S-1 (TPS) in patients with locally advanced or recurrent/metastatic head and neck cancer

scientific article published on 07 June 2010

Phase II feasibility trial of adjuvant chemoradiotherapy with 3-weekly cisplatin for Japanese patients with post-operative high-risk squamous cell carcinoma of the head and neck

scientific article published on 23 August 2012

Phase II trial of chemoradiotherapy with S-1 plus cisplatin for unresectable locally advanced head and neck cancer (JCOG0706).

scientific article published on April 2015

Phase II trial of concurrent chemoradiotherapy with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck: Japan Clinical Oncology Group Study (JCOG0706).

scientific article published on 8 May 2009

Prediction of glomerular filtration rate in cancer patients by an equation for Japanese estimated glomerular filtration rate

scientific article

Prognostic value of ALDH2 polymorphism for patients with oropharyngeal cancer in a Japanese population.

scientific article published on 5 December 2017

Prognostic value of FDG PET imaging in patients with laryngeal cancer

scientific article

Prospective Cohort Study of Performance Status and Activities of Daily Living After Surgery for Spinal Metastasis.

scientific article

Quality of life and cost-utility of surgical treatment for patients with spinal metastases: prospective cohort study.

scientific article published on 10 April 2017

Quality-of-Life Priorities in Patients with Thyroid Cancer: A Multinational European Organisation for Research and Treatment of Cancer Phase I Study.

scientific article

Radiotherapy for stage I or II hypopharyngeal carcinoma

scientific article

Randomized phase II/III trial of post-operative chemoradiotherapy comparing 3-weekly cisplatin with weekly cisplatin in high-risk patients with squamous cell carcinoma of head and neck: Japan Clinical Oncology Group Study (JCOG1008).

scientific article published on 19 May 2014

Randomized phase III study to evaluate the value of omission of prophylactic neck dissection for stage I/II tongue cancer: Japan Clinical Oncology Group study (JCOG1601, RESPOND)

scientific article published on 01 December 2018

Randomized trial of standard pain control with or without gabapentin for pain related to radiation-induced mucositis in head and neck cancer

scientific article published on 15 March 2016

Rapid improvement of glucagonoma-related necrolytic migratory erythema with octreotide.

scientific article published on 9 April 2014

Regulation of MET kinase inhibitor resistance by copy number of MET in gastric carcinoma cells

scientific article

Remarkable response to cetuximab-containing chemotherapy for tongue cancer refractory to immune checkpoint inhibitors

scientific article published on 01 October 2017

Role of intensive nutrition support and prophylactic percutaneous endoscopic gastrostomy during concomitant chemoradiotherapy for oropharyngeal cancer

scientific article published on 18 August 2018

Safety and Effectiveness of Lenvatinib in 594 Patients with Unresectable Thyroid Cancer in an All-Case Post-Marketing Observational Study in Japan

scientific article published on 16 July 2020

Sites of invasion of cancer of the external auditory canal predicting oncologic outcomes

scientific article published in 2021

Subgroup analysis of Japanese patients in a phase 3 study of lenvatinib in radioiodine-refractory differentiated thyroid cancer

scientific article

Successful neutrophil engraftment by reduced use of granulocyte colony-stimulating factor after allogeneic hematopoietic stem cell transplantation with mycophenolate mofetil for graft-versus-host disease prophylaxis.

scientific article published on 22 April 2011

Successful treatment switch from lenvatinib to sorafenib in a patient with radioactive iodine-refractory differentiated thyroid cancer intolerant to lenvatinib due to severe proteinuria.

scientific article

Systemic chemotherapy with cisplatin plus 5-FU (PF) for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN): efficacy and safety of a lower dose of PF (80/800) at a single institution in Japan.

scientific article

TYRO3 as a potential therapeutic target in breast cancer

scientific article

The EORTC module for quality of life in patients with thyroid cancer: phase III.

scientific article published on 21 February 2017

The combination of HLA-B*15:01 and DRB1*15:01 is associated with gemcitabine plus erlotinib-induced interstitial lung disease in patients with advanced pancreatic cancer

scientific article published on 21 April 2016

Thrombotic Microangiopathy with Severe Proteinuria Induced by Lenvatinib for Radioactive Iodine-Refractory Papillary Thyroid Carcinoma

Treatment-emergent hypertension and efficacy in the phase 3 Study of (E7080) lenvatinib in differentiated cancer of the thyroid (SELECT).

scientific article published on 14 April 2018

Two-year follow-up of a randomized phase III clinical trial of nivolumab vs. the investigator's choice of therapy in the Asian population for recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141)

scientific article published on 24 June 2020

Validity of new methods to evaluate renal function in cancer patients treated with cisplatin

scientific article published on 20 January 2016

Weekly Low-Dose Versus Three-Weekly High-Dose Cisplatin for Concurrent Chemoradiation in Locoregionally Advanced Non-Nasopharyngeal Head and Neck Cancer: A Systematic Review and Meta-Analysis of Aggregate Data.

scientific article

[18F]Fluorodeoxyglucose uptake by positron emission tomography predicts outcomes for oropharyngeal and hypopharyngeal cancer treated with definitive radiotherapy

scientific article published on February 2017

[Concurrent chemoradiotherapy with cisplatin for locally advanced squamous cell carcinoma of head and neck]

[III. Non-Surgical Treatment Strategy for Locally Advanced Laryngeal and Hypopharyngeal Cancer]

[Molecular targeting treatment for thyroid cancer]

scientific article published on 01 July 2015