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List of works by Douglas P. Gladue

A partial deletion in non-structural protein 3A can attenuate foot-and-mouth disease virus in cattle

scientific article published on 6 September 2013

A partial deletion within foot-and-mouth disease virus non-structural protein 3A causes clinical attenuation in cattle but does not prevent subclinical infection

scientific article published on 12 January 2018

ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever

scientific article published on 27 April 2021

African Swine Fever Virus Georgia 2007 with a Deletion of Virulence-Associated Gene 9GL (B119L), when Administered at Low Doses, Leads to Virus Attenuation in Swine and Induces an Effective Protection against Homologous Challenge

scientific article published on 10 June 2015

African Swine Fever Virus Georgia Isolate Harboring Deletions of MGF360 and MGF505 Genes Is Attenuated in Swine and Confers Protection against Challenge with Virulent Parental Virus

scientific article

African swine fever virus Georgia isolate harboring deletions of 9GL and MGF360/505 genes is highly attenuated in swine but does not confer protection against parental virus challenge

scientific article published on 12 May 2016

African swine fever virus vaccine candidate ASFV‐G‐ Δ I177L efficiently protects European and native pig breeds against circulating Vietnamese field strain

scientific article published on 15 October 2021

Alteration of a Second Putative Fusion Peptide of Structural Glycoprotein E2 of Classical Swine Fever Virus Alters Virus Replication and Virulence in Swine

scientific article published on 07 September 2016

Alteration of the N-linked glycosylation condition in E1 glycoprotein of Classical Swine Fever Virus strain Brescia alters virulence in swine.

scientific article

Association of the Host Immune Response with Protection Using a Live Attenuated African Swine Fever Virus Model

scientific article published on 22 October 2016

CRISPR-Cas9, a tool to efficiently increase the development of recombinant African swine fever viruses

scientific article published on 16 February 2018

Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum

scholarly article by Douglas P Gladue published in August 2018

Classical swine fever virus p7 protein is a viroporin involved in virulence in swine

scientific article

DEP-domain-mediated regulation of GPCR signaling responses.

scientific article

Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine

scientific article published on 20 October 2020

Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine

scientific article published on 16 January 2020

Deletion of the H108R Gene Reduces Virulence of the Pandemic Eurasia Strain of African Swine Fever Virus with Surviving Animals Being Protected against Virulent Challenge

scientific article published on 06 July 2022

Deletion of the thymidine kinase gene induces complete attenuation of the Georgia isolate of African swine fever virus

scientific article published on 4 December 2015

Development of a live attenuated antigenic marker classical swine fever vaccine.

scientific article published on December 2008

Development of an improved live attenuated antigenic marker CSF vaccine strain candidate with an increased genetic stability.

scientific article

Early protection events in swine immunized with an experimental live attenuated classical swine fever marker vaccine, FlagT4G.

scientific article

Effect of specific amino acid substitutions in the putative fusion peptide of structural glycoprotein E2 on Classical Swine Fever Virus replication

scientific article

Effects of the interactions of classical swine fever virus Core protein with proteins of the SUMOylation pathway on virulence in swine ⬇️

scientific article published on November 10, 2010

Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene

scientific article published on 20 October 2020

Evaluation in Swine of a Recombinant Georgia 2010 African Swine Fever Virus Lacking the I8L Gene

scientific article published on 29 December 2020

Evaluation of the Deletion of MGF110-5L-6L on Swine Virulence from the Pandemic Strain of African Swine Fever Virus and Use as a DIVA Marker in Vaccine Candidate ASFV-G-ΔI177L

scientific article published on 11 July 2022

Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-ΔI177L

scientific article published on 25 April 2022

Foot-and-mouth disease virus modulates cellular vimentin for virus survival

scientific article published on 10 April 2013

Foot-and-mouth disease virus nonstructural protein 2C interacts with Beclin1, modulating virus replication.

scientific article

Identification of a Continuously Stable and Commercially Available Cell Line for the Identification of Infectious African Swine Fever Virus in Clinical Samples

scientific article published on 28 July 2020

Identification of an NTPase motif in classical swine fever virus NS4B protein.

scientific article published on 13 January 2011

Interaction between Core protein of classical swine fever virus with cellular IQGAP1 protein appears essential for virulence in swine ⬇️

scientific article published on January 23, 2011

Interaction of CSFV E2 protein with swine host factors as detected by yeast two-hybrid system

scientific article

Interaction of Structural Glycoprotein E2 of Classical Swine Fever Virus with Protein Phosphatase 1 Catalytic Subunit Beta (PPP1CB).

scientific article

Interaction of foot-and-mouth disease virus nonstructural protein 3A with host protein DCTN3 is important for viral virulence in cattle

scientific article published on 18 December 2013

Interaction of structural core protein of classical swine fever virus with endoplasmic reticulum-associated degradation pathway protein OS9.

scientific article published on 4 June 2014

Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages

scientific article published on 14 November 2019

Mutation-induced changes of transmembrane pore size revealed by combined ion-channel conductance and single vesicle permeabilization analyses.

scientific article published on 6 January 2018

Patterns of gene expression in swine macrophages infected with classical swine fever virus detected by microarray.

scientific article published on 17 March 2010

Phylodynamics of parapoxvirus genus in Mexico (2007-2011)

scientific article published on 04 July 2018

Pore-forming activity of pestivirus p7 in a minimal model system supports genus-specific viroporin function.

scientific article

SERTA Domain Containing Protein 1 (SERTAD1) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2, Which Is Involved in Virus Virulence in Swine

scientific article published on 09 April 2020

Scanning mutagenesis of regions in the Galpha protein Gpa1 that are predicted to interact with yeast mating pheromone receptors

scientific article published on 24 September 2007

Selective Factors Associated with the Evolution of Codon Usage in Natural Populations of Arboviruses

scientific article

Simultaneous Deletion of the 9GL and UK Genes from the African Swine Fever Virus Georgia 2007 Isolate Offers Increased Safety and Protection against Homologous Challenge

scientific article published on 26 October 2016

Substitution of specific cysteine residues in the E1 glycoprotein of classical swine fever virus strain Brescia affects formation of E1-E2 heterodimers and alters virulence in swine.

scientific article published on 11 May 2011

Swine Host Protein Coiled-Coil Domain-Containing 115 (CCDC115) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2 during Virus Replication

scientific article published on 31 March 2020

The C962R ORF of African Swine Fever Strain Georgia Is Non-Essential and Not Required for Virulence in Swine

scientific article published on 23 June 2020

The Ep152R ORF of African swine fever virus strain Georgia encodes for an essential gene that interacts with host protein BAG6.

scientific article published on 3 August 2016

The L83L ORF of African swine fever virus strain Georgia encodes for a non-essential gene that interacts with the host protein IL-1β.

scientific article

The MGF360-16R ORF of African Swine Fever Virus Strain Georgia Encodes for a Nonessential Gene That Interacts with Host Proteins SERTAD3 and SDCBP

scientific article published on 03 January 2020

The progressive adaptation of a georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major modifications of the viral genome

scientific article published on 10 December 2014

Virus-host interactions in persistently FMDV-infected cells derived from bovine pharynx

scientific article published on 12 September 2014

X69R Is a Non-Essential Gene That, When Deleted from African Swine Fever, Does Not Affect Virulence in Swine

scientific article published on 21 August 2020

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