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List of works by Juleen Zierath

2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training

article

2001 Minkowski Prize-36th Minkowski Lecture

scientific article published in October 2001

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice

scientific article

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

scientific article published in May 2003

5-aminoimidazole-4-carboxy-amide-1-beta-D-ribofuranoside treatment ameliorates hyperglycaemia and hyperinsulinaemia but not dyslipidaemia in KKAy-CETP mice

scientific article published in December 2001

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

scientific article

A new twist on brown fat metabolism

scientific article published in April 2009

A simple and rapid method to characterize lipid fate in skeletal muscle

scientific article

AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase

scientific article published on 14 October 2009

AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle

scientific journal article

AMP-activated protein kinase signaling in metabolic regulation

scientific article published on July 2006

AMPK activation negatively regulates GDAP1, which influences metabolic processes and circadian gene expression in skeletal muscle

scientific article published on 25 July 2018

AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits

scientific article published on 01 July 2006

AMPKγ3 is dispensable for skeletal muscle hypertrophy induced by functional overload

scientific article published on 12 January 2016

Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients.

scientific article published on 23 August 2003

Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans.

scientific article

Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells

scientific article

Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men.

scientific article published on 13 July 2015

Acute exercise remodels promoter methylation in human skeletal muscle.

scientific article

Adenosine 5'-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle

scientific article published on 17 January 2008

Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals with type 2 diabetes: a randomised crossover trial

scientific article published on 13 November 2018

Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients

scientific article published on 02 January 2016

Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle

scientific article published on 12 April 2017

Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass

scientific article published on 28 January 2014

Altered response of skeletal muscle to IL-6 in type 2 diabetic patients

scientific article published on 18 October 2012

Analysis of insulin signaling pathways through comparative genomics. Mapping mechanisms for insulin resistance in type 2 (non-insulin-dependent) diabetes mellitus.

scientific article

Analysis of paradoxical observations on the association between leptin and insulin resistance

scientific article

Arterial stiffness estimation in healthy subjects: a validation of oscillometric (Arteriograph) and tonometric (SphygmoCor) techniques

scientific article published on 24 July 2014

Association of the ACTN3 R577X polymorphism with glucose tolerance and gene expression of sarcomeric proteins in human skeletal muscle

scientific article

Author Correction: Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression

scientific article published on 08 October 2020

Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7.

scientific article published on 8 October 2013

Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism

scientific article published on 26 September 2015

Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise

scientific article

Building Bridges through Scientific Conferences

scientific article published on November 2016

C-peptide revisited--new physiological effects and therapeutic implications

scientific article published on September 1996

C-peptide stimulates glucose transport in isolated human skeletal muscle independent of insulin receptor and tyrosine kinase activation

scientific article published on 01 March 1996

Calcineurin Regulates Skeletal Muscle Metabolism via Coordinated Changes in Gene Expression

scientific article published in Journal of Biological Chemistry

Carrier-mediated fructose uptake significantly contributes to carbohydrate metabolism in human skeletal muscle

scientific article published on October 1995

Changes in Vitamin D Status in Overweight Middle-Aged Adults with or without Impaired Glucose Metabolism in Two Consecutive Nordic Summers

article

Changes in exercise-induced gene expression in 5'-AMP-activated protein kinase gamma3-null and gamma3 R225Q transgenic mice

scientific article

Changes in gene expression in responders and nonresponders to a low-intensity walking intervention

scientific article published on 20 March 2015

Changes in glucose transport and protein kinase Cβ 2 in rat skeletal muscle induced by hyperglycaemia

scientific article published on 01 September 1999

Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men

scientific article published on 06 August 2020

Circadian rhythms and exercise - re-setting the clock in metabolic disease

scientific article published on 01 April 2019

Circulating Exosomal miR-20b-5p Is Elevated in Type 2 Diabetes and Could Impair Insulin Action in Human Skeletal Muscle

scientific article published on 14 December 2018

Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism

scientific article published on 11 December 2019

Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes

scientific article published on 5 October 2012

Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity

scientific article published on 27 October 2009

Contraction influences Per2 gene expression in skeletal muscle through a calcium-dependent pathway

scientific article published on 16 September 2020

Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle

scientific article published on 26 July 2013

DNA methylation in metabolic disorders ⬇️

scientific article published on 02 February 2011

Development of decreased insulin-induced glucose transport in skeletal muscle of glucose-intolerant hybrids of diabetic GK rats

scientific article published in March 1995

Diabetologia at 50: celebrating half a century of progress in diabetes research and care

scientific article published in August 2015

Diacylglycerol kinase α deficiency alters inflammation markers in adipose tissue in response to high fat diet.

scientific article published on 12 December 2017

Diacylglycerol kinase-δ regulates AMPK signaling, lipid metabolism, and skeletal muscle energetics

scientific article

Differential Regulation of Phosphoinositide 3-Kinase Adapter Subunit Variants by Insulin in Human Skeletal Muscle ⬇️

scientific article published on July 25, 1997

Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.

scientific article published in January 2006

Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta

scientific article

Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

scientific article published in March 2011

Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes

scientific article published on 4 March 2016

Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

scientific article published in Science

Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes

scientific article published in March 2004

Distinctive exercise-induced inflammatory response and exerkine induction in skeletal muscle of people with type 2 diabetes

scientific article published in 2022

Divergent cell signaling after short-term intensified endurance training in human skeletal muscle

scientific article published on 30 September 2008

Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance

scientific article published in February 2008

Dynamic epigenetic responses to muscle contraction.

scientific article published on 12 March 2014

Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans

article

Effect of a novel non-thiazolidinedione peroxisome proliferator-activated receptor alpha/gamma agonist on glucose uptake

scientific article published on March 2007

Effect of human C-peptide on glucose transport in in vitro incubated human skeletal muscle

scientific article published on December 1991

Effect of insulin on GLUT4 cell surface content and turnover rate in human skeletal muscle as measured by the exofacial bis-mannose photolabeling technique.

scientific article published on December 1997

Effect of leptin treatment on mitochondrial function in obese leptin-deficient ob/ob mice

scientific article published on 08 May 2013

Effect of metformin on insulin-stimulated glucose transport in isolated skeletal muscle obtained from patients with NIDDM.

scientific article

Effect of the nicotine metabolite 5'-hydroxycotinine on glucose transport and glycogen synthase activity in rat skeletal muscle

scientific article published on 01 December 1999

Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice

scientific article published on 31 January 2014

Effects of Nordic walking on cardiovascular risk factors in overweight individuals with type 2 diabetes, impaired or normal glucose tolerance

scientific article published on 01 January 2013

Effects of Nordic walking on health-related quality of life in overweight individuals with type 2 diabetes mellitus, impaired or normal glucose tolerance.

scientific article published on November 2011

Effects of calcineurin activation on insulin-, AICAR- and contraction-induced glucose transport in skeletal muscle

scientific article published on 23 June 2005

Effects of exercise on mitogen- and stress-activated kinase signal transduction in human skeletal muscle

scientific article published on 01 November 2000

Effects of glycaemia on glucose transport in isolated skeletal muscle from patients with NIDDM: in vitro reversal of muscular insulin resistance

scientific article published on 01 March 1994

Effects of high-fat diet and AMPK modulation on the regulation of whole-body lipid metabolism.

scientific article published on 8 May 2018

Effects of insulin, contraction, and phorbol esters on mitogen-activated protein kinase signaling in skeletal muscle from lean and ob/ob mice

scientific article

Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study

scientific article published in May 2005

Effects of non-esterified fatty acids on insulin-stimulated glucose transport in isolated skeletal muscle from patients with type 2 (non-insulin-dependent) diabetes mellitus

scientific article published on 01 September 1994

Effects of sleeping with reduced carbohydrate availability on acute training responses

scientific article published on 25 June 2015

Elevated free fatty acid levels inhibit glucose phosphorylation in slow-twitch rat skeletal muscle

scientific article published on 01 May 1994

Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism

scientific article published on 12 October 2021

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK.

scientific article published on 26 October 2016

Enhanced insulin-stimulated glycogen synthesis in response to insulin, metformin or rosiglitazone is associated with increased mRNA expression of GLUT4 and peroxisomal proliferator activator receptor gamma co-activator 1.

scientific article published on 30 April 2005

Epigenetic flexibility in metabolic regulation: disease cause and prevention?

scientific article published on 29 December 2012

Erratum to: Turning the page

scientific article published on 01 December 2015

Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes

scientific article

Evidence against high glucose as a mediator of ERK1/2 or p38 MAPK phosphorylation in rat skeletal muscle

scientific article published in December 2001

Evidence for non-CpG methylation in mammals.

scientific article published on 7 September 2011

Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver

scientific article published on 4 February 2006

Exercise Promotes Healthy Aging of Skeletal Muscle

scientific article published on June 2016

Exercise in the management of non-insulin-dependent diabetes mellitus

scientific article published on January 1998

Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle.

scientific article published on 22 March 2010

Exercise metabolism and the molecular regulation of skeletal muscle adaptation

scientific article

Exercise remodels subcutaneous fat tissue and improves metabolism

scientific article published on 24 February 2015

Exercise training in obese diabetic patients. Special considerations

scientific article published on September 1, 1992

Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes

scientific article published on 26 September 2006

Exercise-Induced Phosphorylation of the Novel Akt Substrates AS160 and Filamin A in Human Skeletal Muscle

scientific article published on 01 June 2006

Exercise-Induced Protein Kinase C Isoform-Specific Activation in Human Skeletal Muscle

scientific article published on 01 January 2004

Exercise-associated differences in an array of proteins involved in signal transduction and glucose transport.

scientific article

Exercise-induced mitogen-activated protein kinase signalling in skeletal muscle

scientific article published in May 2004

Exercise-induced overexpression of key regulatory proteins involved in glucose uptake and metabolism in tetraplegic persons: molecular mechanism for improved glucose homeostasis

scientific article published on 01 December 1998

Exercise-induced phospho-proteins in skeletal muscle.

scientific article published on September 2008

Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.

scientific article published in September 2005

Expression of carnitine palmitoyl-CoA transferase-1B is influenced by a cis-acting eQTL in two chicken lines selected for high and low body weight

scientific article published on 19 March 2013

Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle

scientific article

FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle.

scientific article

Fighting the battle of the bulge: exercise training in early-onset type 2 diabetes

scientific article published on 01 July 2007

Fine-tuning insulin and nitric oxide signalling by turning up the AMPs: new insights into AMP-activated protein kinase signalling

scientific article

GLUT4 translocation in human muscle strips

scientific article published on 01 August 1997

Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle

scientific article published on 6 October 2008

Gene expression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in skeletal muscle from type 2 diabetic subjects

scientific article published on 11 September 2002

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

scientific article

Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM.

scientific article published in August 1994

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

scientific article published on 7 September 2022

Globular adiponectin stimulates glucose transport in type 2 diabetic muscle

scientific article published in October 2008

Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.

scientific article

Glutamate is a positive autocrine signal for glucagon release

scientific article published on June 2008

Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

scientific article

High-Fat Feeding Impairs Insulin-Stimulated GLUT4 Recruitment via an Early Insulin-Signaling Defect

scientific article published on 01 February 1997

High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring.

scientific article published on 25 December 2015

Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance

scientific article published on January 2017

Human islet amyloid polypeptide at pharmacological levels inhibits insulin and phorbol ester-stimulated glucose transport in in vitro incubated human muscle strips.

scientific article published in January 1992

Hunting for the SNARK in metabolic disease

scientific article published on 24 March 2009

Hyperglycemia Activates Glucose Transport in Rat Skeletal Muscle Via a Ca2+-Dependent Mechanism

scientific article published on 01 November 1995

IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients.

scientific article published in March 2006

Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity

scientific article published on 01 March 1995

Identification of two microRNA nodes as potential cooperative modulators of liver metabolism

scientific article published on 11 September 2019

Impaired insulin action on phosphatidylinositol 3-kinase activity and glucose transport in skeletal muscle of pancreatic cancer patients

scientific article published on March 2003

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training.

scientific article

Impaired phosphocreatine metabolism in white adipocytes promotes inflammation

scientific article published on 14 February 2022

Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats

scientific article published in December 1997

In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle

scientific article published on September 1999

In vitro studies of human skeletal muscle: hormonal and metabolic regulation of glucose transport.

scientific article published on January 1995

Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet

scientific article published on 31 May 2013

Influence of AMP-activated protein kinase and calcineurin on metabolic networks in skeletal muscle

scientific article published on 10 June 2008

Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression

scientific article published on 15 October 2019

Influence of physical activity and gender on arterial function in type 2 diabetes, normal and impaired glucose tolerance

scientific article published on 19 June 2015

Insulin Signaling and Glucose Transport in Skeletal Muscle From First-Degree Relatives of Type 2 Diabetic Patients

scientific article published on 01 May 2006

Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content.

scientific article

Insulin action in skeletal muscle from patients with NIDDM.

scientific article published in May 1998

Insulin action on expression of novel adipose genes in healthy and type 2 diabetic subjects

scientific article published in January 2004

Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM.

scientific article published in October 1996

Insulin action on glucose transport in isolated skeletal muscle from patients with liver cirrhosis.

scientific article

Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle

scientific article published on 23 December 2016

Insulin induces translocation of GLUT-4 glucose transporters in human skeletal muscle

scientific article published on 01 April 1995

Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation

scientific article published on March 1997

Insulin signal transduction and glucose transport in human adipocytes: effects of obesity and low calorie diet

scientific article

Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

scientific article published in December 2001

Insulin signaling and glucose transport in insulin resistant human skeletal muscle

scientific article published on January 2007

Insulin signaling and glucose transport in insulin resistant skeletal muscle. Special reference to GLUT4 transgenic and GLUT4 knockout mice.

scientific article published in January 1998

Insulin signaling defects in type 2 diabetes

scientific article published on May 2004

Insulin signalling and resistance in patients with chronic heart failure

scientific article published on 9 May 2003

Insulin- and glucose-induced phosphorylation of the Na(+),K(+)-adenosine triphosphatase alpha-subunits in rat skeletal muscle

scientific article published in August 2001

Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

scientific article published on September 2000

Insulin-like growth factor II stimulates glucose transport in human skeletal muscle

scientific article published on 01 August 1992

Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects

scientific article published in August 1998

Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects

scientific journal article

Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation

scientific journal article

Intact glucose transport in morphologically altered denervated skeletal muscle from quadriplegic patients

scientific article published on 01 September 1996

Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

scientific article published on 27 January 2022

Integration of mathematical and experimental approaches to resolve insulin signalling

scientific article published in January 2005

Integration of metabolic and mitogenic signal transduction in skeletal muscle.

scientific article published on January 2004

Integrative biology of exercise

scientific article

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

scientific article published on March 2010

Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle

scientific article published on 15 March 2007

Interplay between diet, exercise and the molecular circadian clock in orchestrating metabolic adaptations of adipose tissue

scientific article published on 28 January 2019

Invited review: Exercise training-induced changes in insulin signaling in skeletal muscle

scientific article

Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism

scientific article published on 01 October 1997

Isoform-specific regulation of 5' AMP-activated protein kinase in skeletal muscle from obese Zucker (fa/fa) rats in response to contraction

scientific article published in September 2002

Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression

scientific article

Kinases in diabetes. Part I. 11-12 November 2004, Manchester, UK

scientific article published on 01 February 2005

Kinases in diabetes. Part II. 11-12 November 2004, Manchester, UK

scientific article published on 01 February 2005

Kinetics of GLUT4 trafficking in rat and human skeletal muscle

scientific article published on 2 February 2009

L-Arginine enhances glucose and lipid metabolism in rat L6 myotubes via the NO/ c-GMP pathway

scientific article published on 11 August 2012

Looking Ahead Perspective: Where Will the Future of Exercise Biology Take Us?

scientific article published on July 2015

Low-intensity exercise increases skeletal muscle protein expression of PPARδ and UCP3 in type 2 diabetic patients

scientific article published on 01 November 2006

MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.

scientific article

MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways

scientific article published on 11 February 2004

Major Advances and Discoveries in Diabetes - 2019 in Review

scientific article published on 04 November 2019

Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle

scientific article

Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle

scientific article published on 01 October 2001

Mechanisms behind insulin resistance in rat skeletal muscle after oophorectomy and additional testosterone treatment

scientific article

Metabolic adaptations in skeletal muscle overexpressing GLUT4: effects on muscle and physical activity

scientific article published in April 2001

Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise

article

Metabolic and molecular consequences of modifying GLUT4 expression in skeletal muscle

scientific article published on August 1997

Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

scientific article

MicroRNA-208b progressively declines after spinal cord injury in humans and is inversely related to myostatin expression

scientific article

Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus

scientific article published on 03 August 2011

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

scientific journal article

Modified UCN2 Peptide Acts as an Insulin Sensitizer in Skeletal Muscle of Obese Mice

scientific article published on 22 April 2019

Molecular mechanisms of skeletal muscle insulin resistance in type 2 diabetes.

scientific article published on May 2005

Molecular mechanisms underlying insulin resistance in skeletal muscle

scientific article published on November 2010

Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes

scientific article published in January 2015

Muscle damage impairs insulin stimulation of IRS-1, PI 3-kinase, and Akt-kinase in human skeletal muscle

scientific article

Muscle-specific transgenic complementation of GLUT4-deficient mice. Effects on glucose but not lipid metabolism ⬇️

scientific article published on August 1, 1997

Neuregulins mediate calcium-induced glucose transport during muscle contraction

scientific journal article

Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle.

scientific article published on 27 March 2010

Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.

scientific article published in September 2009

Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans.

scientific article published on 6 December 2015

Opposite transcriptional regulation in skeletal muscle of AMP-activated protein kinase gamma3 R225Q transgenic versus knock-out mice

scientific article published on 12 January 2006

Overexpression of Ha-ras selectively in adipose tissue of transgenic mice. Evidence for enhanced sensitivity to insulin

scientific article

Paternal high-fat diet transgenerationally impacts hepatic immunometabolism

scientific article published on 15 February 2019

Phosphatidylinositol 3-kinase-mediated endocytosis of renal Na+, K+-ATPase alpha subunit in response to dopamine

scientific article

Polymyxin B inhibits stimulation of glucose transport in muscle by hypoxia or contractions

scientific article published on May 1989

Postexercise glucose uptake and glycogen synthesis in skeletal muscle from GLUT4-deficient mice.

scientific article published on December 1999

Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle.

scientific article published on 28 February 2009

Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner.

scientific article

Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake

scientific article published on 18 May 2004

Proteasome inhibition in skeletal muscle cells unmasks metabolic derangements in type 2 diabetes

scientific article published on 20 August 2014

Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition

scientific article published on 19 January 2018

Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway.

scientific article published in November 1998

Regulation of glucose uptake and inflammation markers by FOXO1 and FOXO3 in skeletal muscle

scientific article published on 16 November 2018

Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training

scientific article published on 24 June 2013

Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes.

scientific article published on 04 August 2009

Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle

scientific article

Remembering our classics: then and now ⬇️

scientific article published on October 25, 2011

Research Highlights: Nutritional status affects the epigenomic profile of peripheral blood cells

scientific article published on 01 June 2011

Restoration of hypoxia-stimulated glucose uptake in GLUT4-deficient muscles by muscle-specific GLUT4 transgenic complementation

scientific article published in August 1998

Role of AMP--activated protein kinase in the control of glucose homeostasis.

scientific article

Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle

scientific article published on 20 October 2005

Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle

scientific article published on 25 September 2008

Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling

scientific article

Role of skeletal muscle in thiazolidinedione insulin sensitizer (PPARgamma agonist) action

scientific article

Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle

scientific article published on 13 October 2009

Sending the signal: molecular mechanisms regulating glucose uptake

scientific article published in July 2004

Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle.

scientific article published on 15 October 2013

Skeletal Muscle Insulin Sensitivity Show Circadian Rhythmicity Which Is Independent of Exercise Training Status

scientific article published on 28 August 2018

Skeletal muscle AMP-activated protein kinase γ1(H151R) overexpression enhances whole body energy homeostasis and insulin sensitivity

scientific article

Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression

scientific article

Skeletal muscle and insulin sensitivity: pathophysiological alterations.

scientific article

Skeletal muscle fiber type: influence on contractile and metabolic properties

scientific article

Skeletal muscle insulin resistance after trauma: insulin signaling and glucose transport.

scientific article

Skeletal muscle insulin resistance: is it important for the pathogenesis of type 2 diabetes after all?

scientific article published in July 2003

Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways

scientific article published on 26 August 2003

SnapShot: Exercise Metabolism

scientific article published in August 2016

Spatial insulin signalling in isolated skeletal muscle preparations

scientific article published in April 2010

Specific cleavage of insulin-like growth factor-binding protein-1 by a novel protease activity

scientific article published on October 2006

Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA.

scientific article published on 31 March 2009

Strenuous physical exercise adversely affects monocyte chemotaxis

scientific article published on 26 October 2010

T cell-mediated inflammation in adipose tissue does not cause insulin resistance in hyperlipidemic mice

scientific article

TXNIP regulates peripheral glucose metabolism in humans

scientific article

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

scientific article

Temporal analysis of reciprocal miRNA-mRNA expression patterns predicts regulatory networks during differentiation in human skeletal muscle cells

scientific article

The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle

scientific article

The Path to Insulin Resistance: Paved with Ceramides?

scientific article published on 01 March 2007

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

scientific article published on 12 June 2012

The effect of hyperglycaemia on glucose disposal and insulin signal transduction in skeletal muscle

scientific article

The effects of exercise mode, swimming vs. running, upon bone growth in the rapidly growing female rat

scientific article published on January 1, 1992

The estrogen receptor {alpha}-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms

scientific article

The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells

scientific article published on 9 June 2010

The role of diet and exercise in the transgenerational epigenetic landscape of T2DM.

scientific article published on 17 June 2016

Time course analysis reveals gene-specific transcript and protein kinetics of adaptation to short-term aerobic exercise training in human skeletal muscle

scientific article

Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis

scientific article published on 18 April 2019

Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression

scientific article published on 16 September 2020

Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes.

scientific article published on 17 January 2012

Train like an athlete: applying exercise interventions to manage type 2 diabetes

scientific article published on 11 June 2020

Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans.

scientific article published on 9 November 2017

Transcriptomic and epigenomics atlas of myotubes reveals insight into the circadian control of metabolism and development

scientific article published on 11 March 2020

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

scientific article published on 24 January 2020

Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation

scientific article published in October 2005

Turning the page

scientific article published on 01 December 2015

Uncoupling protein 3 is reduced in skeletal muscle of NIDDM patients ⬇️

scientific article published on September 1, 1998

Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients

scientific article published on April 2000

Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action

scientific article published on 07 February 2019

Weight loss after gastric bypass surgery in human obesity remodels promoter methylation

scientific article published on 11 April 2013

Xth International Symposium on insulin receptors and insulin action

scientific article published in January 2008

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

scientific article

mRNA expression of diacylglycerol kinase isoforms in insulin-sensitive tissues: effects of obesity and insulin resistance

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siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle

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