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List of works by David A Hume

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Interferon-γ: an overview of signals, mechanisms and functions

scientific article (publication date: February 2004)
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

scientific article
An atlas of active enhancers across human cell types and tissues

scientific article
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

scientific article (publication date: 5 December 2002)
A promoter-level mammalian expression atlas

scientific article
Genome-wide analysis of mammalian promoter architecture and evolution

scientific article (publication date: June 2006)
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

scientific journal article
The regulated retrotransposon transcriptome of mammalian cells

scientific article (publication date: May 2009)
Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

scientific article
IFITM3 restricts the morbidity and mortality associated with influenza

scientific article
An atlas of combinatorial transcriptional regulation in mouse and man

scientific article
Functional annotation of a full-length mouse cDNA collection

scientific article (publication date: 8 February 2001)
Somatic retrotransposition alters the genetic landscape of the human brain

scientific article (publication date: 30 October 2011)
A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse.

scientific article published on 12 September 2002
Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome

scientific article
Mammalian RNA polymerase II core promoters: insights from genome-wide studies

scientific article published on 8 May 2007
Unravelling mononuclear phagocyte heterogeneity

scientific article
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

scientific article
Macrophages as APC and the dendritic cell myth

scientific article
Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo

scientific article published in July 2008
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

scientific article
Expression analysis of G Protein-Coupled Receptors in mouse macrophages

scientific article
The mononuclear phagocyte system

scientific article
Tiny RNAs associated with transcription start sites in animals

scientific article published on 19 April 2009
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2

scientific journal article
Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling.

scientific article published on 20 December 2011
The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans

scientific journal article
CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

scientific article published on 09 March 2009
An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

scientific article published on 3 August 2010
Apoptotic cell removal in development and tissue homeostasis

scientific article
IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

scientific article published on 07 October 2013
The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Relationship between macrophages, Langerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs.

scientific article
Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

scientific article published on September 2015
Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

scientific article
Signal integration between IFNgamma and TLR signalling pathways in macrophages

scientific article published on 5 July 2006
Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function

scientific article published in June 2011
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

scientific article
Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter

scientific article published on 25 May 2007
Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome

scientific article
LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression

scientific article published on July 2006
Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia

scientific article
Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs

scientific article published in April 2006
Identification of putative noncoding RNAs among the RIKEN mouse full-length cDNA collection

scientific article (publication date: June 2003)
A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis

scientific article
Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity

scientific article published on 17 December 2010
The molecular basis for the lack of immunostimulatory activity of vertebrate DNA.

scientific article
The mononuclear phagocyte system of the mouse defined by immunohistochemical localisation of antigen F4/80: macrophages associated with epithelia.

scientific article published on November 1984
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.

scientific article published on 16 April 2007
The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion

scientific article published in August 2005
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment

article

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