List of works - Kenneth D Westover

A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase

scientific article published on 30 December 2019

ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis

scientific article published on 01 March 2022

Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations

scientific article

Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold"

scientific article published on 13 August 2020

Development of small molecules targeting the pseudokinase Her3.

scientific article published on 11 May 2015

Discovery of a selective inhibitor of doublecortin like kinase 1

scientific article published on 06 April 2020

GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R

scientific article published on 18 March 2020

Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide

scientific article published on 03 October 2019

KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation

scientific article published on 13 December 2017

KRASQ61H preferentially signals through MAPK in a RAF dimer-dependent manner in non-small cell lung cancer

scientific article published on 30 June 2020

Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations

scientific article published on 23 July 2021

Mycotic aneurysm of the left main coronary artery producing acute coronary occlusion and purulent pericarditis

scientific article published on 21 July 2006

Nonsteroidal anti-inflammatory drugs, acetaminophen, cyclooxygenase 2, and fever.

scientific article

Precision Hypofractionated Radiation Therapy in Poor Performing Patients With Non-Small Cell Lung Cancer: Phase 1 Dose Escalation Trial

scientific article published on 9 May 2015

Publisher Correction: Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide

scientific article published on 30 December 2019

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

scientific article

Radiation therapy as a backbone of treatment of locally advanced non-small cell lung cancer

scientific article published on 12 December 2013

Rationale for RAS mutation-tailored therapies.

scientific article

SABR for aggressive local therapy of metastatic cancer: A new paradigm for metastatic non-small cell lung cancer.

scientific article published on 08 May 2015

Significance testing as perverse probabilistic reasoning

scientific article

Stereotactic ablative radiotherapy (SABR) for non-small cell lung cancer

scientific article

Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine

scientific article published on 21 November 2016

Structural basis of eukaryotic gene transcription

scientific article

Structural basis of the atypical activation mechanism of KRASV14I

scientific article published on 24 July 2019

Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center

scientific article

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis

scientific article

Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine

scientific article published on 30 January 2020

Structure-guided development of covalent TAK1 inhibitors

scientific article published on 9 December 2016

Tissue-Specific Oncogenic Activity of KRASA146T

scientific article published on 05 April 2019

Treatment of non-small cell lung cancer patients with proton beam-based stereotactic body radiotherapy: dosimetric comparison with photon plans highlights importance of range uncertainty

scientific article

List of works by Kenneth D Westover

A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase

ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis

Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations

Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold"

Development of small molecules targeting the pseudokinase Her3.

Discovery of a selective inhibitor of doublecortin like kinase 1

GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R

Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide

KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation

KRASQ61H preferentially signals through MAPK in a RAF dimer-dependent manner in non-small cell lung cancer

Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations

Mycotic aneurysm of the left main coronary artery producing acute coronary occlusion and purulent pericarditis

Nonsteroidal anti-inflammatory drugs, acetaminophen, cyclooxygenase 2, and fever.

Precision Hypofractionated Radiation Therapy in Poor Performing Patients With Non-Small Cell Lung Cancer: Phase 1 Dose Escalation Trial

Publisher Correction: Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

Radiation therapy as a backbone of treatment of locally advanced non-small cell lung cancer

Rationale for RAS mutation-tailored therapies.

SABR for aggressive local therapy of metastatic cancer: A new paradigm for metastatic non-small cell lung cancer.

Significance testing as perverse probabilistic reasoning

Stereotactic ablative radiotherapy (SABR) for non-small cell lung cancer

Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine

Structural basis of eukaryotic gene transcription

Structural basis of the atypical activation mechanism of KRASV14I

Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis

Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine

Structure-guided development of covalent TAK1 inhibitors

Tissue-Specific Oncogenic Activity of KRASA146T

Treatment of non-small cell lung cancer patients with proton beam-based stereotactic body radiotherapy: dosimetric comparison with photon plans highlights importance of range uncertainty