List of works by Brian Matthews

A helix initiation signal in T4 lysozyme identified by polyalanine mutagenesis

scientific article

A model binding site for testing scoring functions in molecular docking

scientific article

A review about nothing: are apolar cavities in proteins really empty?

scientific article

A test of proposed rules for helix capping: Implications for protein design

scientific article

Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation

scientific article published on 31 August 2004

Bifunctional abietadiene synthase: mutual structural dependence of the active sites for protonation-initiated and ionization-initiated cyclizations

scientific article

Boron Mimetics: 1,2-Dihydro-1,2-azaborines Bind inside a Nonpolar Cavity of T4 Lysozyme

scientific article

Changes to crystals of Escherichia coli beta-galactosidase during room-temperature/low-temperature cycling and their relation to cryo-annealing

scientific article published on 17 October 2007

Co-repressor induced order and biotin repressor dimerization: a case for divergent followed by convergent evolution

scientific article published on 6 January 2006

Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme

scientific article

Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation

scientific article

Cryo-cooling in macromolecular crystallography: advantages, disadvantages and optimization

scientific article

Crystal structure of E. coli YhbY: a representative of a novel class of RNA binding proteins

scientific article

Crystal structure of the BstDEAD N-terminal domain: a novel DEAD protein from Bacillus stearothermophilus

scientific article

Crystal structures of a T4-lysozyme duplication-extension mutant demonstrate that the highly conserved beta-sheet region has low intrinsic folding propensity

scientific article

Crystallization of beta-galactosidase does not reduce the range of activity of individual molecules

scientific article

David Davies: Structural biologist and mentor

scientific article

Determination of solvent content in cavities in IL-1beta using experimentally phased electron density

scientific article

Direct and indirect roles of His-418 in metal binding and in the activity of β-galactosidase (E. coli)

scientific article

Dissection of protein structure and folding by directed mutagenesis ⬇️

scientific article published on January 1, 1992

Dynamics of xenon binding inside the hydrophobic cavity of pseudo-wild-type bacteriophage T4 lysozyme explored through xenon-based NMR spectroscopy

scientific article published in August 2005

Editorial

Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression

scientific article

Evaluation at atomic resolution of the role of strain in destabilizing the temperature-sensitive T4 lysozyme mutant Arg 96 → His

scientific article

Extension to 2268 atoms of direct methods in theab initiodetermination of the unknown structure of bacteriophage P22 lysozyme

scientific article published on 18 January 2006

Five retracted structure reports: inverted or incorrect?

scientific article

Generation of noble-gas binding sites for crystallographic phasing using site-directed mutagenesis.

scientific article published on 21 December 2001

Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme

scientific article

Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding

scientific article

How planar are planar peptide bonds?

scientific article published on 16 February 2016

Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome

scientific article

Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases

scientific article published on 01 June 2006

Interactive graphics return to protein science.

scientific article published on 20 March 2009

Kinetic and spectroscopic characterization of the H178A methionyl aminopeptidase from Escherichia coli

scientific article published in May 2003

LacZ β-galactosidase: structure and function of an enzyme of historical and molecular biological importance

scientific article

Lessons from the lysozyme of phage T4

scientific article

Long-distance conformational changes in a protein engineered by modulated sequence duplication

scientific article

Metalloaminopeptidases: common functional themes in disparate structural surroundings

scientific article (publication date: December 2002)

Methods in Protein Science.

scientific article

Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability

scientific article (publication date: 2003)

Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function

scientific article

Peripatetic proteins

scientific article published on July 2010

Protein Science "Best Paper" awards to Youngil Chang and Liam Longo

scientific article published on July 2013

Protein Science Best Paper awards to Chih-Chia (Jack) Su and Minttu Virkki

scientific article published in March 2015

Protein Science best paper awards to Minfei Su and Chang-Ting Lin

scientific article published on 01 May 2018

Protein Science best paper awards to Tracy Clinton and Michael Thompson

scientific article published on 16 March 2016

Protein Science best paper awards to Yu-ming Huang and Abhay Thakur

scientific article published on 01 June 2019

Protein Structure Initiative: getting into gear.

scientific article

Protein science "best paper" awards to Mark Landau and Brian Ziemba

scientific article published on 2 April 2014

Proteins under pressure

scientific article

Purification, crystallization and preliminary X-ray analysis of the novel DEAD protein BstDEAD fromBacillus stearothermophilus ⬇️

scientific article published on September 19, 2003

Racemic crystallography--easy crystals and easy structures: what's not to like?

scientific article

Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis

scientific article published in May 2002

Relocation or duplication of the helix A sequence of T4 lysozyme causes only modest changes in structure but can increase or decrease the rate of folding

scientific article

Repacking the Core of T4 lysozyme by automated design

scientific article

Selling candles in a post-Edison world: phasing with noble gases bound within engineered sites ⬇️

scientific article published on October 23, 2003

Sequential reorganization of beta-sheet topology by insertion of a single strand

scientific article

Sorting the chaff from the wheat at the PDB.

scientific article published in January 2009

Stoichiometry versus hydrophobicity in protein folding

scientific article published on 01 February 2011

Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli β-Galactosidase† ⬇️

scientific article published on November 25, 2003

Structural Rigidity of a Large Cavity-containing Protein Revealed by High-pressure Crystallography

scientific article

Structural analysis of silanediols as transition-state-analogue inhibitors of the benchmark metalloprotease thermolysin

scientific article

Structural analysis of the group II intron splicing factor CRS2 yields insights into its protein and RNA interaction surfaces.

scientific article

Structural and thermodynamic characterization of T4 lysozyme mutants and the contribution of internal cavities to pressure denaturation

scientific article published on 25 September 2008

Structural basis for the attachment of a paramyxoviral polymerase to its template

scientific article

Structural basis for the functional differences between type I and type II human methionine aminopeptidases

scientific article

Structural basis for the unusual specificity of Escherichia coli aminopeptidase N

scientific article

Structural basis of Prospero-DNA interaction: implications for transcription regulation in developing cells

scientific article published on 01 April 2005

Structural basis of the action of thermolysin and related zinc peptidases

Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site

scholarly article

Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain

scientific article

Structure of the Nucleocapsid-Binding Domain from the Mumps Virus Polymerase; an Example of Protein Folding Induced by Crystallization

scientific article

Structure of the angiogenesis inhibitor ovalicin bound to its noncognate target, human Type 1 methionine aminopeptidase

scientific article

Structure of the constitutively active double mutant CheYD13K Y106W alone and in complex with a FliM peptide

scientific article published in September 2004

Testing a flexible-receptor docking algorithm in a model binding site

scientific article

The Bragg legacy: early days in macromolecular crystallography

scientific article published on 5 December 2012

The mirrored methionine sulfoxide reductases of Neisseria gonorrhoeae pilB

scientific article

The role of solvent transport in cryo-annealing of macromolecular crystals

scientific article published on 25 February 2004

The structure of E. coli beta-galactosidase

scientific article

Thermolysin in the absence of substrate has an open conformation

scientific article

Tools for protein science.

scientific article published in January 2018

Transformations in structural biology: a personal view.

scientific article

Use of an ion-binding site to bypass the 1000-atom limit to structure determination by direct methods.

scientific article published on 23 September 2004

Use of experimental crystallographic phases to examine the hydration of polar and nonpolar cavities in T4 lysozyme

scientific article

Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme

scholarly article

Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme

scientific article

Which of the 100,000 structures in the protein data bank are reliable?

scientific article

[1] Recent transformations in structural biology

scientific article published on 01 January 1997

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