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List of works by Ramiro Iglesias-Bartolome

A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.

scientific article published on 21 November 2012

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers

scientific article published on 13 February 2016

Activation of GPCR-Gαi signaling increases keratinocyte proliferation and reduces differentiation, leading to epidermal hyperplasia

scientific article published on 07 November 2019

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

scientific article published in Nature Communications

Cellular Systems for Studying Human Oral Squamous Cell Carcinomas ⬇️

scientific article published on January 1, 2011

Combining portable Raman probes with nanotubes for theranostic applications

scientific article

Complex gangliosides are apically sorted in polarized MDCK cells and internalized by clathrin-independent endocytosis

scientific article

Control of the epithelial stem cell epigenome: the shaping of epithelial stem cell identity.

scientific article published on 19 February 2013

Critical role of evolutionarily conserved glycosylation at Asn211 in the intracellular trafficking and activity of sialyltransferase ST3Gal-II.

scientific article

Differential endocytic trafficking of neuropathy-associated antibodies to GM1 ganglioside and cholera toxin in epithelial and neural cells.

scientific article published on 2 October 2009

Expression of an active Gαs mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance.

scientific article

Fluorescent, bioactive protein nanoparticles (prodots) for rapid, improved cellular uptake.

scientific article

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

scientific article published on 11 March 2019

Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.

scientific article

Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.

scientific article published on 11 May 2015

Keeping the epidermal stem cell niche in shape

scientific article published on 01 August 2010

Metabolic pathways and intracellular trafficking of gangliosides

scientific article published on July 2011

Nuclear mapping of nanodrug delivery systems in dynamic cellular environments

scientific article

Policing Tumorigenesis within the Skin: Good Outs Bad.

scientific article published in October 2017

Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands.

scientific article published on 06 March 2016

Signaling circuitries controlling stem cell fate: to be or not to be ⬇️

scientific article published on August 29, 2011

Targeted delivery of immunotoxin by antibody to ganglioside GD3: a novel drug delivery route for tumor cells

scientific article

The antibody to GD3 ganglioside, R24, is rapidly endocytosed and recycled to the plasma membrane via the endocytic recycling compartment. Inhibitory effect of brefeldin A and monensin

scientific article published in April 2006

The landscape of GPCR signaling in the regulation of epidermal stem cell fate and skin homeostasis

scientific article published on 07 September 2020

Transcriptional signature primes human oral mucosa for rapid wound healing.

scientific article published in July 2018

YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity

scientific article published on 19 March 2020

mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations

scientific article

mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis.

scientific article

mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model.

scientific article published on 18 August 2016

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