Search filters

List of works by Margaret Nieborowska-Skorska

BCR-ABL1 kinase facilitates localization of acetylated histones 3 and 4 on DNA double-strand breaks

scientific article published on 28 October 2011

BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair

scientific article published on September 2008

BCR/ABL inhibits mismatch repair to protect from apoptosis and induce point mutations

scientific article

BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistance

scientific article published on 9 March 2006

BCR/ABL recruits p53 tumor suppressor protein to induce drug resistance

scientific article

Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-triggered TIAR-mediated suppression of translation

scientific article

Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells

scientific article

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells

scientific article published on 8 May 2017

Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

scientific article published on 29 March 2013

Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes

scientific article published on 27 October 2016

Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases

scientific article published on 10 February 2016

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas.

scientific article published on 27 September 2016

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile

scientific article

Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

scientific article

Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms.

scientific article published on 17 October 2017

Targeting RAD51 phosphotyrosine-315 to prevent unfaithful recombination repair in BCR-ABL1 leukemia ⬇️

scientific article published on June 7, 2011

Paulina is supported by:

About Paulina

Help