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List of works by Heiko van der Kuip

A Temperature of 40 °C Appears to be a Critical Threshold for Potentiating Cytotoxic Chemotherapy In Vitro and in Peritoneal Carcinomatosis Patients Undergoing HIPEC.

scientific article published on 8 September 2015

A cell-based screen for resistance of Bcr-Abl-positive leukemia identifies the mutation pattern for PD166326, an alternative Abl kinase inhibitor

scientific article published on 30 September 2004

Apoptosis of mesothelial cells caused by unphysiological characteristics of peritoneal dialysis fluids

scientific article published in November 2003

Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices

scientific article published on 9 December 2015

Cellular uptake of imatinib into leukemic cells is independent of human organic cation transporter 1 (OCT1).

scientific article published on 18 December 2013

Cisplatin hypersensitivity of testicular germ cell tumors is determined by high constitutive Noxa levels mediated by Oct-4.

scientific article published on 9 January 2013

Cytokeratin-18 is a useful serum biomarker for early determination of response of breast carcinomas to chemotherapy

scientific article

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

scientific article

Dasatinib reverses cancer-associated fibroblasts (CAFs) from primary lung carcinomas to a phenotype comparable to that of normal fibroblasts

scientific article published on 27 June 2010

Estrogen-mediated downregulation of CD24 in breast cancer cells

scientific article published on July 2008

Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast

scientific article

Imaging of myocardial infarction using ultrasmall superparamagnetic iron oxide nanoparticles: a human study using a multi-parametric cardiovascular magnetic resonance imaging approach

scientific article published on 26 October 2012

Imatinib mesylate (STI571) prevents the mutator phenotype of Bcr-Abl in hematopoietic cell lines

scientific article published on April 2004

Imatinib mesylate induces cisplatin hypersensitivity in Bcr-Abl+ cells by differential modulation of p53 transcriptional and proapoptotic activity

scientific article published in December 2009

Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571).

scientific article published on 15 May 2003

Mechanisms of clinical resistance to small molecule tyrosine kinase inhibitors targeting oncogenic tyrosine kinases

scientific article

Methylomes of renal cell lines and tumors or metastases differ significantly with impact on pharmacogenes

scientific article published on 20 July 2016

Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases

scientific article published on 10 February 2016

Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis

scientific article

Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project

scientific article published on 21 November 2017

Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

scientific article

Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters

scientific article published in March 2002

Short term culture of breast cancer tissues to study the activity of the anticancer drug taxol in an intact tumor environment

scientific article

Telomere length and telomerase activity in the BCR-ABL-transformed murine Pro-B cell line BaF3 is unaffected by treatment with imatinib

scientific article published in May 2005

Therapeutic options for chronic myeloid leukemia: focus on imatinib (Glivec, Gleevectrade mark).

scientific article published on February 2008

Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo

scientific article published on September 2014

c-erbB2 and topoisomerase IIalpha protein expression independently predict poor survival in primary human breast cancer: a retrospective study

scientific article

p53 hypersensitivity is the predominant mechanism of the unique responsiveness of testicular germ cell tumor (TGCT) cells to cisplatin

scientific article

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