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List of works by Helena Edlund

-Cell Neogenesis in an Animal Model of IDDM

scientific article published on 01 April 1997

Asna1/TRC40 Controls β-Cell Function and Endoplasmic Reticulum Homeostasis by Ensuring Retrograde Transport

scientific article published on 5 October 2015

Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function

scientific article published in October 2005

Attenuation of FGF signalling in mouse β-cells leads to diabetes

scientific article published in Nature

BMP4-BMPR1A Signaling in β Cells Is Required for and Augments Glucose-Stimulated Insulin Secretion

scientific article published on 01 March 2007

Defective glucose-regulated insulin gene expression associated with PDX-1 deficiency in the Psammomys obesus model of type 2 diabetes

scientific article

Developmental biology of the pancreas.

scientific article

Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes

scientific article

Endocrine cell clustering during human pancreas development

scientific article published on 13 April 2009

Factors controlling pancreatic cell differentiation and function.

scientific article

Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells

scientific article

Gastric Amylin Expression: Cellular Identity and Lack of Requirement for the Homeobox Protein PDX-1. A Study in Normal and PDX-1-Deficient Animals with a Cautionary Note on Antiserum Evaluation

scientific article published on 01 August 1999

Gene array identification of Ipf1/Pdx1-/- regulated genes in pancreatic progenitor cells

scientific article

Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion

scientific article published on 2 June 2008

Homeobox gene product Nkx 6.1 immunoreactivity in nuclei of endocrine cells of rat and mouse stomach

scientific article published in June 1998

Hyperinsulinemia Enhances Hepatic Expression of the Fatty Acid Transporter Cd36 and Provokes Hepatosteatosis and Hepatic Insulin Resistance

scientific article published on 17 June 2015

IPF1, a homeodomain protein with a dual function in pancreas development.

scientific article published in October 1995

IPF1/PDX1 deficiency and beta-cell dysfunction in Psammomys obesus, an animal With type 2 diabetes

scientific article published in August 2001

Increased islet apoptosis in Pdx1+/- mice

scientific article

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

scientific article

Insulin promoter factor-1 controls several aspects of beta-cell identity

scientific article published on 01 February 2001

Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner

scientific article published on 31 July 2015

Insulin-promoter-factor 1 is required for pancreas development in mice

scientific article (publication date: 13 October 1994)

MFng is dispensable for mouse pancreas development and function

scientific article published on 17 February 2009

MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas

scientific article

Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas

scientific article published on 01 May 2002

Notch signalling controls pancreatic cell differentiation

scientific journal article

Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion.

scientific article

Of mice and MEN1: Insulinomas in a conditional mouse knockout

scientific article published on September 2003

Overexpression of extracellular-SOD in islets of nonobese diabetic mice and development of diabetes

article

Pancreatic organogenesis--developmental mechanisms and implications for therapy

scientific article

Pancreatic-duodenal homeobox 1 -role in gastric endocrine patterning

scientific article published on 01 December 1996

Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development

scientific article

Pdx1 maintains β cell identity and function by repressing an α cell program

scientific article published on February 2014

Persistent expression of Hlxb9 in the pancreatic epithelium impairs pancreatic development

scientific article published in December 2001

Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms

scientific article published on 11 January 2006

Ptf1a determines horizontal and amacrine cell fates during mouse retinal development

scientific journal article

Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells

scientific article

Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9

scientific journal article

Sequence-specific interactions of nuclear factors with the insulin gene enhancer.

scientific article published in April 1986

Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

scientific journal article

TAT-mediated neurogenin 3 protein transduction stimulates pancreatic endocrine differentiation in vitro.

scientific article published on March 2005

The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival

scientific article published on 27 November 2017

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse

scientific article published in April 2005

The anterior chamber of the eye is a transplantation site that supports and enables visualisation of beta cell development in mice

scientific article published on 4 February 2016

The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site.

scientific article

The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity

scientific article

The insulin gene promoter. A simplified nomenclature

scientific article

The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice

scientific journal article

The pancreatic beta-cell-specific transcription factor Pax-4 inhibits glucagon gene expression through Pax-6.

scientific article

The thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretion

scientific article (publication date: October 2011)

The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells

scientific article published on 24 January 2013

Toward a renewable source of pancreatic beta-cells

scientific article published in April 2008

beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

scientific article

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

scientific article published in June 1998

sox4b is a key player of pancreatic alpha cell differentiation in zebrafish

scientific article published in September 2005

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