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List of works by Tsukasa Oikawa

A novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclasts

scientific article

ARF1 recruits RAC1 to leading edge in neutrophil chemotaxis

scientific article published on 2 October 2017

Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion.

scientific article published on 28 June 2013

Epithelial-specific histone modification of the miR-96/182 locus targeting AMAP1 mRNA predisposes p53 to suppress cell invasion in epithelial cells

scientific article published on 04 December 2018

Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model

scientific article published on 5 January 2018

High expression of EPB41L5, an integral component of the Arf6-driven mesenchymal program, correlates with poor prognosis of squamous cell carcinoma of the tongue.

scientific article

IRSp53 mediates podosome formation via VASP in NIH-Src cells

scientific article published on 26 March 2013

Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.

scientific article published on 8 February 2016

Necessity of p53-binding to the CDH1 locus for its expression defines two epithelial cell types differing in their integrity.

scientific article

P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance.

scientific article

Possible role of IRTKS in Tks5-driven osteoclast fusion ⬇️

scientific article published on September 1, 2012

PtdIns(3,4)P2 instigates focal adhesions to generate podosomes.

scientific article published on 29 April 2009

PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia

scientific article published on 25 April 2004

Rac-WAVE-mediated actin reorganization is required for organization and maintenance of cell-cell adhesion.

scientific article published on 12 December 2006

Regulation of osteoclasts by membrane-derived lipid mediators

scientific article

Sequential signals toward podosome formation in NIH-src cells.

scientific article

The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformation

scientific article

Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusion

scientific article

Tumor responsiveness to statins requires overexpression of the ARF6 pathway

scientific article published on 13 May 2016

ZEB1 induces EPB41L5 in the cancer mesenchymal program that drives ARF6-based invasion, metastasis and drug resistance

scientific article published on 12 September 2016

p53-Dependent and -Independent Epithelial Integrity: Beyond miRNAs and Metabolic Fluctuations.

scientific article published on 25 May 2018

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