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List of works by Susan D Richman

A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO).

scientific article published on 13 August 2013

Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in CDH1 Is a Prognostic Marker of Survival ⬇️

scientific article published on 14 April 2015

Artificial intelligence for detection of microsatellite instability in colorectal cancer-a multicentric analysis of a pre-screening tool for clinical application

scientific article published on 02 March 2022

Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer ⬇️

scientific article published on 26 October 2017

Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial

scientific article published on 26 October 2009

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification ⬇️

scientific article published on 31 May 2017

Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer

scientific article

Confirmation that somatic mutations of beta-2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial

scientific article published on 05 July 2019

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer ⬇️

scientific article published on 27 June 2017

Exploring outcomes of RAS-mutant (RAS mut) advanced colorectal cancer (aCRC) treated with chemotherapy: Analysis from 2254 patients (pts) in randomised clinical trials (RCTs) ⬇️

Failure to validate toxicity and outcome biomarkers from the FFCD 2000-05 trial in the MRC CR08 FOCUS trial

scientific article published on 21 March 2011

How close are we to standardised extended RAS gene mutation testing? The UK NEQAS evaluation ⬇️

scientific article published on 28 September 2016

Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing.

scientific article published in January 2011

KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial

scientific article published on 2 November 2009

KRAS mutation analysis on low percentage of colon cancer cells: the importance of quality assurance

scientific article published on 15 December 2012

Left and right sided large bowel cancer

scientific article published on April 2002

MLH1 −93G>A promoter polymorphism and risk of mismatch repair deficient colorectal cancer

Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN, and FOCUS studies

scientific article

Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial

scientific article published on 29 May 2013

Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial ⬇️

scientific article

Prediction of the response of colorectal cancer to systemic therapy

scientific article

Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial

scientific article published in June 2008

RAS screening in colorectal cancer: a comprehensive analysis of the results from the UK NEQAS colorectal cancer external quality assurance schemes (2009-2016). ⬇️

scientific article

Response

Results of the UK NEQAS for Molecular Genetics reference sample analysis ⬇️

article

Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis

scientific article published on 12 July 2013

Standardising RNA profiling based biomarker application in cancer-The need for robust control of technical variables ⬇️

scientific article published on 23 May 2017

Targeted next generation sequencing reveals a common genetic pathway for colorectal cancers with chromosomal instability and those with microsatellite and chromosome stability

scientific article published on 20 May 2019

Value of mismatch repair, KRAS, and BRAF mutations in predicting recurrence and benefits from chemotherapy in colorectal cancer.

scientific article published on 7 March 2011

What can the molecular pathologist offer for optimal decision making?

scientific article published on October 2010

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