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List of works by Jean-Paul Borg

8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways

scientific article

A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding.

scientific article

A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment

scientific article published on 10 June 2008

A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib.

scientific article published on 22 December 2016

A serum protein signature with high diagnostic value in bacterial endocarditis: results from a study based on surface-enhanced laser desorption/ionization time-of-flight mass spectrometry

scientific article

A simplified, 96-well-adapted, ATP luminescence-based motility assay

scientific article published in October 2009

Activation peptide of the coagulation factor XIII (AP-F13A1) as a new biomarker for the screening of colorectal cancer.

scientific article published on 9 April 2018

Activity-Dependent Neuroplasticity Induced by an Enriched Environment Reverses Cognitive Deficits in Scribble Deficient Mouse.

scientific article

Amine-guanidine switch: a promising approach to improve DNA binding and antiproliferative activities

scientific article published on 4 December 2007

AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.

scientific article published on August 2014

Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis

scientific journal article

Apicobasal polarity complexes.

scientific article published in November 2005

Assignment of vascular endothelial growth factor (VEGF) and placenta growth factor (PLGF) genes to human chromosome 6p12-p21 and 14q24-q31 regions, respectively

scientific article

Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway.

scientific article

Author Correction: SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations

scientific article published on 14 May 2020

BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators

scientific article published on 03 September 2021

Basolateral targeting by leucine-rich repeat domains in epithelial cells ⬇️

scientific article published on October 24, 2003

Biochemical characterization of two isoforms of FLT4, a VEGF receptor-related tyrosine kinase

scientific article

Biochemical studies and molecular dynamics simulations of Smad3-Erbin interaction identify a non-classical Erbin PDZ binding.

scientific article

C2orf62 and TTC17 are involved in actin organization and ciliogenesis in zebrafish and human

scientific article

Cell polarity and adherens junction formation inhibit epithelial Fas cell death receptor signaling

scientific article published on 21 September 2018

Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins

scientific article

Collective nomenclature for LAP proteins

scientific article published in July 2000

Down-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer.

scientific article

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer

scientific article published on 11 April 2019

EFA6 regulates lumen formation through alpha-actinin 1.

scientific article

ERBB2 oncogenicity: ERBIN helps to perform the job.

scientific article published on 19 March 2015

ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor

scientific article published in July 2000

Early prognostic factors in septic shock cancer patients: a prospective study with a proteomic approach.

scientific article published on 7 January 2018

Epithelial barrier dysfunction in desmoglein-1 deficiency

scientific article published on 27 April 2018

Erbin Suppresses KSR1-Mediated RAS/RAF Signaling and Tumorigenesis in Colorectal Cancer.

scientific article

Erbin and the NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF-beta.

scientific article published on March 2009

Erbin interacts with TARP γ-2 for surface expression of AMPA receptors in cortical interneurons.

scientific article

Erbin is a negative modulator of cardiac hypertrophy

scientific article published on 07 April 2014

Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis

scientific article published on June 2015

Function of PTB Domains ⬇️

scientific article published on January 1, 1998

Functional analysis of the Numb phosphotyrosine-binding domain using site-directed mutagenesis

scientific article published on 01 April 1998

Gene expression profiling of breast tumor cell lines to predict for therapeutic response to microtubule-stabilizing agents.

scientific article

Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis.

scientific article

Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear.

scientific article

Hook2 is involved in the morphogenesis of the primary cilium

scientific article published on 12 October 2011

How may targeted proteomics complement genomic data in breast cancer?

scientific article

Human immunodeficiency virus-1 reverse transcriptase immunodominant CD4+ T cell epitopes: a peptide-based multiparametric assessment in the mouse.

scientific article

Human nectin3/PRR3: a novel member of the PVR/PRR/nectin family that interacts with afadin

scientific article (publication date: 19 September 2000)

Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins

scientific article published on 2 April 2014

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer

scientific article

Insight into planar cell polarity

scientific article

Interaction with the Phosphotyrosine Binding Domain/Phosphotyrosine Interacting Domain of SHC Is Required for the Transforming Activity of the FLT4/VEGFR3 Receptor Tyrosine Kinase

scientific article published in Journal of Biological Chemistry

Junctional recruitment of mammalian Scribble relies on E-cadherin engagement

scientific article (publication date: 23 June 2005)

LAP proteins are localized at the post-synaptic membrane of neuromuscular junctions and appear to modulate synaptic morphology and transmission.

scientific article published on 20 June 2016

LAP proteins: new gatekeepers of epithelial homeostasis

scientific article

MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm

scientific article

MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells

scientific article

MMP2 and MMP9 serum levels are associated with favorable outcome in patients with inflammatory breast cancer treated with bevacizumab-based neoadjuvant chemotherapy in the BEVERLY-2 study.

scientific article

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

scientific article

Mapping Cellular Polarity Networks Using Mass Spectrometry-based Strategies

scientific article published on 18 May 2018

Masked selection: a straightforward and flexible approach for the selection of binders against specific epitopes and differentially expressed proteins by phage display

scientific article published on 20 December 2013

Modeling Heterogeneity of Triple-Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

scientific article published on 16 December 2020

Modeling Heterogeneity of Triple-Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains.

scientific article

Modulation of estrogen related receptor alpha activity by the kinesin KIF17.

scientific article published on 23 May 2017

Molecular analysis of the X11-mLin-2/CASK complex in brain

scientific article

Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes

scientific article

Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16.

scientific article

Mutation at tyrosine residue 1337 abrogates ligand-dependent transforming capacity of the FLT4 receptor

scientific article

Neural tube defects: from a proteomic standpoint

scientific article

New LKB1 function in the primary cilium.

scientific article published on 13 July 2015

OFIP/KIAA0753 forms a complex with OFD1 and FOR20 at pericentriolar satellites and centrosomes and is mutated in one individual with oral-facial-digital syndrome.

scientific article published on 7 December 2015

Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer

scientific article published on 11 May 2015

PDZ Domain Proteins: Plug and Play! ⬇️

scientific article published on April 22, 2003

PICK-1: a scaffold protein that interacts with Nectins and JAMs at cell junctions

scientific article

PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2.

scientific article

Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation.

scientific article

Poly(ADP-ribose) polymerase 1 (PARP1) overexpression in human breast cancer stem cells and resistance to olaparib.

scientific article published on 21 August 2014

Poly(ADP-ribose) polymerase-1 mRNA expression in human breast cancer: a meta-analysis.

scientific article published on 11 November 2010

Postoperative serum proteomic profiles and identification of biomarkers with prognosis value in high-risk early breast cancer patients

Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments

scientific article

Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton.

scientific article published on 11 August 2013

Proteic profiling SELDI-TOF and breast cancer: clinical potential applications

scientific article

Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypes

scientific article

Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling

scientific article

Ptk7-Deficient Mice Have Decreased Hematopoietic Stem Cell Pools as a Result of Deregulated Proliferation and Migration.

scientific article published on 18 April 2016

Publisher Correction: SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations

scientific article published on 14 May 2020

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay

scientific article published on 8 June 2015

Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family.

scientific article published in August 2016

Recruitment of FOR20 and OFD1 onto pericentriolar satellites and centrosomes depends on the formation of a ternary complex with KIAA0753.

scientific article published on 13 July 2015

Regulation of LKB1/STRAD localization and function by E-cadherin

scientific article

Role of Erbin in ErbB2-dependent breast tumor growth.

scientific article

Role of tyrosine residues and protein interaction domains of SHC adaptor in VEGF receptor 3 signaling

scientific article

SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations

scientific article published on 11 May 2020

Scrib regulates PAK activity during the cell migration process

scientific article

Semaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancers

scientific article

Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain

scientific article

Tetraspanin-6 negatively regulates exosome production

scientific article published on 27 February 2020

The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins

scientific article (publication date: 4 May 2001)

The GIT-PIX protein complex: a hub to ARF and Rac/Cdc42 GTPases

scientific article published in October 2005

The LAP family: a phylogenetic point of view

scientific article published on 01 October 2002

The NOD2-RICK complex signals from the plasma membrane.

scientific article published on 13 March 2007

The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway.

scientific article

The Planar Cell Polarity Vangl2 protein: from genetics to cellular and molecular functions

scientific article published on 27 October 2017

The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling

The Scribble family in cancer: twentieth anniversary

scientific article published on 30 September 2020

The Tumor Suppressor SCRIB is a Negative Modulator of the Wnt/β-Catenin Signaling Pathway

scientific article published on 20 October 2019

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

scientific journal article

The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions

scientific article published on 30 May 2013

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

scientific article

The polarity protein Scrib is essential for directed endothelial cell migration

scientific article

The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation.

scientific article published on August 1997

Tridimensional visualization reveals direct communication between the embryo and glands critical for implantation

scientific article published on 9 February 2018

Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis

scientific article published on 30 April 2015

Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma.

scientific article published in March 2018

When mTORC2-AKT signaling meets cell polarity

scientific article published on 27 July 2016

Wnt/Planar Cell Polarity Signaling: New Opportunities for Cancer Treatment

scientific article

ZNF703 gene amplification at 8p12 specifies luminal B breast cancer.

scientific article

[Proteomics and breast cancer: a search for novel diagnostic and theragnostic biomarkers]

scientific article published on 01 March 2010

[Publication of biological samples collections catalogues by tumor banks]

scientific article published on 01 February 2010

[Receptors for factors of the VEGF (Vascular Endothelial Growth Family)]

scientific article published on 01 April 1997

mLin-7 is localized to the basolateral surface of renal epithelia via its NH(2) terminus

scientific journal article

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