List of works - Iris Nagtegaal

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts: National Harbor, MD, USA. 9-13 November 2016.

scientific article published on 8 December 2016

A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned?

scientific article published on 25 May 2009

A study into methodology and application of quantification of tumour vasculature in rectal cancer

scientific article published on 28 May 2004

A uniform residual tumor (R) classification: integration of the R classification and the circumferential margin status.

scientific article

Adjuvant radioimmunotherapy improves survival of rats after resection of colorectal liver metastases

scientific article published on February 2011

Adjuvant tamoxifen reduces subsequent breast cancer in women with estrogen receptor-positive ductal carcinoma in situ: a study based on NSABP protocol B-24.

scientific article published on 5 March 2012

BRAFMutation in Metastatic Colorectal Cancer

scientific article published on 01 July 2009

Brief fixation enables same-day breast cancer diagnosis with reliable assessment of hormone receptors, E-cadherin and HER2/Neu.

scientific article published on 21 March 2017

Cancer classification using the Immunoscore: a worldwide task force

scientific article

Chromosomal and methylation alterations in sporadic and familial adenomatous polyposis-related duodenal carcinomas.

scientific article published on 14 September 2007

Chromosome 20p11 gains are associated with liver-specific metastasis in patients with colorectal cancer

scientific article published on 20 January 2012

Circulating tumour cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents.

scientific article published on 27 October 2009

Circumferential Margin Involvement Is the Crucial Prognostic Factor after Multimodality Treatment in Patients with Locally Advanced Rectal Carcinoma

scientific article published on 01 November 2007

Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit.

scientific article

Clinical Nature and Prognosis of Locally Recurrent Rectal Cancer After Total Mesorectal Excision With or Without Preoperative Radiotherapy

scientific article published on 01 October 2004

Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study

scientific article published in 2022

Clinicopathological features and outcome in advanced colorectal cancer patients with synchronous vs metachronous metastases.

scientific article

Colorectal tumour deposits in the mesorectum and pericolon; a critical review.

scientific article published on 26 May 2007

Combinations of Tumor and Treatment Parameters Are More Discriminative for Prognosis Than the Present TNM System in Rectal Cancer

scientific article published on 01 May 2007

Constitutive expression of γ-H2AX has prognostic relevance in triple negative breast cancer

scientific article

Correcting for lead time and length bias in estimating the effect of screen detection on cancer survival

scientific article published on 25 May 2008

Detecting Lynch syndrome in pancreatic ductal adenocarcinoma FNA cytology based on cancer history and immunocytochemistry

scientific article published in 2021

Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer

scientific article published on 02 July 2012

Diffusion-weighted MR imaging in liver metastases of colorectal cancer: reproducibility and biological validation.

scientific article

Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution

scientific article

ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making

scientific article published on 01 October 2012

EURECCA colorectal: multidisciplinary mission statement on better care for patients with colon and rectal cancer in Europe

scientific article published on 14 June 2013

Evaluation of short-course radiotherapy followed by neoadjuvant bevacizumab, capecitabine, and oxaliplatin and subsequent radical surgical treatment in primary stage IV rectal cancer†

scientific article published on 22 March 2013

Evaluation of yield and experiences of age-related molecular investigation for heritable and nonheritable causes of mismatch repair deficient colorectal cancer to identify Lynch syndrome

scientific article published on 08 June 2020

Evidence-based medicine: the time has come to set standards for staging

scientific article published in August 2010

Expression of carbonic anhydrase IX suggests poor response to therapy in rectal cancer.

scientific article published on 30 June 2009

FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases

scientific article

Focus on Extralevator Perineal Dissection in Supine Position for Low Rectal Cancer Has Led to Better Quality of Surgery and Oncologic Outcome

article

Growth rate alterations of human colorectal cancer cells by 157 gut bacteria

scientific article published on 01 November 2020

Guidelines for reporting histopathology studies

scientific article published on 26 September 2014

Guidelines for reporting histopathology studies.

scientific article published in February 2015

High intrinsic apoptosis, but not radiation-induced apoptosis, predicts better survival in rectal carcinoma patients

scientific article published on 01 October 2003

High-Resolution Array Comparative Genomic Hybridization in Sporadic and Celiac Disease-Related Small Bowel Adenocarcinomas

scientific article published on 23 February 2010

Histopathological evaluation of resected colorectal cancer liver metastases: what should be done?

scientific article published on 13 June 2013

Improvement of staging by combining tumor and treatment parameters: the value for prognostication in rectal cancer.

scientific article published on 4 June 2007

Increased epithelial cell proliferation in the ileal pouch mucosa of patients with familial adenomatous polyposis

scientific article

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

scientific article published in The Lancet

Is the new era of colorectal cancer classification finally here?

scientific article published on 21 May 2013

KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy

scientific article

KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients.

scientific article

Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect--a histopathological and immunohistochemical study

scientific article

Loss of extracellular E-cadherin in the normal mucosa of duodenum and colon of patients with familial adenomatous polyposis.

scientific article

Loss of membranous Ep-CAM in budding colorectal carcinoma cells

scientific article published on 01 February 2007

Low rectal cancer: a call for a change of approach in abdominoperineal resection.

scientific article

Lymph node retrieval in rectal cancer is dependent on many factors--the role of the tumor, the patient, the surgeon, the radiotherapist, and the pathologist.

scientific article published on October 2009

Lymph nodes, tumor deposits, and TNM: are we getting better?

scientific article published on 9 May 2011

Macroscopic Evaluation of Rectal Cancer Resection Specimen: Clinical Significance of the Pathologist in Quality Control

scientific article published on 01 April 2002

Management of sporadic duodenal adenomas and the association with colorectal neoplasms: a retrospective cohort study.

scientific article published in May 2012

Marked improvements in survival of patients with rectal cancer in the Netherlands following changes in therapy, 1989–2006

scientific article published on 19 February 2010

Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab.

scientific article

Mesalazine-induced apoptosis of colorectal cancer: on the verge of a new chemopreventive era?

scientific article published on 01 November 1999

Mesorectal Fascia Instead of Circumferential Resection Margin in Preoperative Staging of Rectal Cancer

scientific article published on 18 April 2011

MicroRNA expression in formalin-fixed paraffin embedded tissue using real time quantitative PCR: the strengths and pitfalls.

scientific article published on April 2012

MicroRNAs in colorectal cancer metastasis.

scientific article published on 27 June 2011

Morphological changes in tumour type after radiotherapy are accompanied by changes in gene expression profile but not in clinical behaviour

article

Mucinous adenocarcinomas: poor prognosis in metastatic colorectal cancer.

scientific article published on 4 January 2012

Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer

scientific article published on 08 September 2020

PIK3CA Mutations Predict Local Recurrences in Rectal Cancer Patients

scientific article published on 10 November 2009

Pathological quality assurance in gastro-intestinal cancer.

scientific article

Pathology is a necessary and informative tool in oncology clinical trials.

scientific article published on January 2014

Population estimates of survival in women with screen-detected and symptomatic breast cancer taking account of lead time and length bias.

scientific article published on 12 July 2008

Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study.

scientific article

Preoperative assessment of the circumferential margin in rectal cancer is more informative in treatment planning than the T stage.

scientific article published on 20 September 2006

Preoperative radiochemotherapy is successful also in patients with locally advanced rectal cancer who have intrinsically high apoptotic tumours.

scientific article published on 29 July 2008

Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer.

scientific article published in August 2001

Prior Colorectal Neoplasia Is Associated With Increased Risk of Ileoanal Pouch Neoplasia in Patients With Inflammatory Bowel Disease

scientific article published on 25 September 2013

Prognosis and pathology of screen-detected carcinomas

scientific article published on 02 November 2010

Prognosis and value of adjuvant chemotherapy in stage III mucinous colorectal carcinoma

scientific article published on 20 September 2013

Prognostic Value of Apoptosis in Rectal Cancer Patients of the Dutch Total Mesorectal Excision Trial: Radiotherapy Is Redundant in Intrinsically High-Apoptotic Tumors

scientific article published on 01 November 2006

Prognostic value of estrogen receptor α and progesterone receptor conversion in distant breast cancer metastases

scientific article published on 13 March 2012

Radiation induces different changes in expression profiles of normal rectal tissue compared with rectal carcinoma.

scientific article published on 16 December 2004

Radiotherapy does not compensate for positive resection margins in rectal cancer patients: report of a multicenter randomized trial

scientific article published on 01 April 2003

Recurrence and variability of germline EPCAM deletions in Lynch syndrome.

scientific article published in March 2011

Reduction in rate of node metastases with breast screening: consistency of association with tumor size.

scientific article published on 23 December 2012

Resection of liver metastases in patients with breast cancer: survival and prognostic factors.

scientific article published on 7 June 2012

Revised staging: is it really better, or do we not know?

scientific article

Risk factors for adverse outcome in patients with rectal cancer treated with an abdominoperineal resection in the total mesorectal excision trial

scientific article published on 01 July 2007

Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

scientific article published on 8 December 2010

Serrated polyps of the colon: how reproducible is their classification?

scientific article published on 6 October 2012

Severe exacerbation of Crohn's disease during sunitinib treatment.

scientific article

Short-course radiotherapy followed by neo-adjuvant chemotherapy in locally advanced rectal cancer--the RAPIDO trial

scientific article

Short-term preoperative radiotherapy interferes with the determination of pathological parameters in rectal cancer

scientific article

Signet ring cell differentiation in mucinous colorectal carcinoma.

scientific article published on July 2007

Sister Joseph's Nodule and pneumatosis: A rare presentation of ovarian cancer

scientific article published on 29 August 2005

Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers

scientific article published on 17 May 2011

Somatic mutations in MLH1 and MSH2 are a frequent cause of mismatch-repair deficiency in Lynch syndrome-like tumors

scientific article published on 10 December 2013

Surgical Treatment of Renal Cell Cancer Liver Metastases: A Population-Based Study ⬇️

scientific article published on February 23, 2011

The CARTS study: Chemoradiation therapy for rectal cancer in the distal rectum followed by organ-sparing transanal endoscopic microsurgery.

scientific article

The Importance of the Pathologist's Role in Assessment of the Quality of the Mesorectum

scientific article

The TME Trial After a Median Follow-up of 6 Years

scientific article published on 01 November 2007

The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology

scientific article published on December 2003

The functional -765G→C polymorphism of the COX-2 gene may reduce the risk of developing crohn's disease

scientific article

The future of the TNM staging system in colorectal cancer: time for a debate?

scientific article published on July 2007

The multidisciplinary treatment of rectal cancer: pathology.

scientific article published on July 2007

The predictive and prognostic value of circulating endothelial cells in advanced colorectal cancer patients receiving first-line chemotherapy and bevacizumab

scientific article published on 28 October 2010

The role of pathologists in the quality control of diagnosis and treatment of rectal cancer-an overview.

scientific article

Towards the introduction of the 'Immunoscore' in the classification of malignant tumours

scientific article

Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response.

scientific article published on 24 August 2011

Visually assessed breast density, breast cancer risk and the importance of the craniocaudal view

scientific article published on 23 July 2008

What is the role for the circumferential margin in the modern treatment of rectal cancer?

scientific article published on January 2008

Young age and a positive family history of colorectal cancer are complementary selection criteria for the identification of Lynch syndrome

scientific article published on 25 January 2011

p53 expression in human rectal tissue after radiotherapy: upregulation in normal mucosa versus functional loss in rectal carcinomas

scientific article published in March 2002

pT3 colorectal cancer revisited: a multicentric study on the histological depth of invasion in more than 1000 pT3 carcinomas—proposal for a new pT3a/pT3b subclassification

scientific article published in 2022

List of works by Iris Nagtegaal

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts: National Harbor, MD, USA. 9-13 November 2016.

A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned?

A study into methodology and application of quantification of tumour vasculature in rectal cancer

A uniform residual tumor (R) classification: integration of the R classification and the circumferential margin status.

Adjuvant radioimmunotherapy improves survival of rats after resection of colorectal liver metastases

Adjuvant tamoxifen reduces subsequent breast cancer in women with estrogen receptor-positive ductal carcinoma in situ: a study based on NSABP protocol B-24.

BRAFMutation in Metastatic Colorectal Cancer

Brief fixation enables same-day breast cancer diagnosis with reliable assessment of hormone receptors, E-cadherin and HER2/Neu.

Cancer classification using the Immunoscore: a worldwide task force

Chromosomal and methylation alterations in sporadic and familial adenomatous polyposis-related duodenal carcinomas.

Chromosome 20p11 gains are associated with liver-specific metastasis in patients with colorectal cancer

Circulating tumour cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents.

Circumferential Margin Involvement Is the Crucial Prognostic Factor after Multimodality Treatment in Patients with Locally Advanced Rectal Carcinoma

Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit.

Clinical Nature and Prognosis of Locally Recurrent Rectal Cancer After Total Mesorectal Excision With or Without Preoperative Radiotherapy

Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study

Clinicopathological features and outcome in advanced colorectal cancer patients with synchronous vs metachronous metastases.

Colorectal tumour deposits in the mesorectum and pericolon; a critical review.

Combinations of Tumor and Treatment Parameters Are More Discriminative for Prognosis Than the Present TNM System in Rectal Cancer

Constitutive expression of γ-H2AX has prognostic relevance in triple negative breast cancer

Correcting for lead time and length bias in estimating the effect of screen detection on cancer survival

Detecting Lynch syndrome in pancreatic ductal adenocarcinoma FNA cytology based on cancer history and immunocytochemistry

Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer

Diffusion-weighted MR imaging in liver metastases of colorectal cancer: reproducibility and biological validation.

Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution

ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making

EURECCA colorectal: multidisciplinary mission statement on better care for patients with colon and rectal cancer in Europe

Evaluation of short-course radiotherapy followed by neoadjuvant bevacizumab, capecitabine, and oxaliplatin and subsequent radical surgical treatment in primary stage IV rectal cancer†

Evaluation of yield and experiences of age-related molecular investigation for heritable and nonheritable causes of mismatch repair deficient colorectal cancer to identify Lynch syndrome

Evidence-based medicine: the time has come to set standards for staging

Expression of carbonic anhydrase IX suggests poor response to therapy in rectal cancer.

FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases

Focus on Extralevator Perineal Dissection in Supine Position for Low Rectal Cancer Has Led to Better Quality of Surgery and Oncologic Outcome

Growth rate alterations of human colorectal cancer cells by 157 gut bacteria

Guidelines for reporting histopathology studies

Guidelines for reporting histopathology studies.

High intrinsic apoptosis, but not radiation-induced apoptosis, predicts better survival in rectal carcinoma patients

High-Resolution Array Comparative Genomic Hybridization in Sporadic and Celiac Disease-Related Small Bowel Adenocarcinomas

Histopathological evaluation of resected colorectal cancer liver metastases: what should be done?

Improvement of staging by combining tumor and treatment parameters: the value for prognostication in rectal cancer.

Increased epithelial cell proliferation in the ileal pouch mucosa of patients with familial adenomatous polyposis

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

Is the new era of colorectal cancer classification finally here?

KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy

KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients.

Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect--a histopathological and immunohistochemical study

Loss of extracellular E-cadherin in the normal mucosa of duodenum and colon of patients with familial adenomatous polyposis.

Loss of membranous Ep-CAM in budding colorectal carcinoma cells

Low rectal cancer: a call for a change of approach in abdominoperineal resection.

Lymph node retrieval in rectal cancer is dependent on many factors--the role of the tumor, the patient, the surgeon, the radiotherapist, and the pathologist.

Lymph nodes, tumor deposits, and TNM: are we getting better?

Macroscopic Evaluation of Rectal Cancer Resection Specimen: Clinical Significance of the Pathologist in Quality Control

Management of sporadic duodenal adenomas and the association with colorectal neoplasms: a retrospective cohort study.

Marked improvements in survival of patients with rectal cancer in the Netherlands following changes in therapy, 1989–2006

Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab.

Mesalazine-induced apoptosis of colorectal cancer: on the verge of a new chemopreventive era?

Mesorectal Fascia Instead of Circumferential Resection Margin in Preoperative Staging of Rectal Cancer

MicroRNA expression in formalin-fixed paraffin embedded tissue using real time quantitative PCR: the strengths and pitfalls.

MicroRNAs in colorectal cancer metastasis.

Morphological changes in tumour type after radiotherapy are accompanied by changes in gene expression profile but not in clinical behaviour

Mucinous adenocarcinomas: poor prognosis in metastatic colorectal cancer.

Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer

PIK3CA Mutations Predict Local Recurrences in Rectal Cancer Patients

Pathological quality assurance in gastro-intestinal cancer.

Pathology is a necessary and informative tool in oncology clinical trials.

Population estimates of survival in women with screen-detected and symptomatic breast cancer taking account of lead time and length bias.

Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study.

Preoperative assessment of the circumferential margin in rectal cancer is more informative in treatment planning than the T stage.

Preoperative radiochemotherapy is successful also in patients with locally advanced rectal cancer who have intrinsically high apoptotic tumours.

Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer.

Prior Colorectal Neoplasia Is Associated With Increased Risk of Ileoanal Pouch Neoplasia in Patients With Inflammatory Bowel Disease

Prognosis and pathology of screen-detected carcinomas

Prognosis and value of adjuvant chemotherapy in stage III mucinous colorectal carcinoma

Prognostic Value of Apoptosis in Rectal Cancer Patients of the Dutch Total Mesorectal Excision Trial: Radiotherapy Is Redundant in Intrinsically High-Apoptotic Tumors

Prognostic value of estrogen receptor α and progesterone receptor conversion in distant breast cancer metastases

Radiation induces different changes in expression profiles of normal rectal tissue compared with rectal carcinoma.

Radiotherapy does not compensate for positive resection margins in rectal cancer patients: report of a multicenter randomized trial

Recurrence and variability of germline EPCAM deletions in Lynch syndrome.

Reduction in rate of node metastases with breast screening: consistency of association with tumor size.