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List of works by Anita Layton

A computational model for simulating solute transport and oxygen consumption along the nephrons

scientific article published on 5 October 2016

A computational model of epithelial solute and water transport along a human nephron

scientific article published on 25 February 2019

A mathematical model of O2 transport in the rat outer medulla. I. Model formulation and baseline results

scientific article published on 29 April 2009

A mathematical model of O2 transport in the rat outer medulla. II. Impact of outer medullary architecture

scientific article published on 29 April 2009

A mathematical model of the myogenic response to systolic pressure in the afferent arteriole ⬇️

scientific article published on December 29, 2010

A mathematical model of the urine concentrating mechanism in the rat renal medulla. I. Formulation and base-case results ⬇️

scientific article published on November 10, 2010

A mathematical model of the urine concentrating mechanism in the rat renal medulla. II. Functional implications of three-dimensional architecture ⬇️

scientific article published on November 10, 2010

A model of mitochondrial O2 consumption and ATP generation in rat proximal tubule cells

scientific article published on 02 December 2019

A new microscope for the kidney: mathematics

scientific article

A numerical method for renal models that represent tubules with abrupt changes in membrane properties

scientific article published in December 2002

A region-based mathematical model of the urine concentrating mechanism in the rat outer medulla. I. Formulation and base-case results

scientific article published on 24 May 2005

A region-based mathematical model of the urine concentrating mechanism in the rat outer medulla. II. Parameter sensitivity and tubular inhomogeneity

scientific article published on 24 May 2005

A region-based model framework for the rat urine concentrating mechanism

scientific article published in September 2003

Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis.

scientific article published on 22 March 2017

An efficient numerical method for distributed-loop models of the urine concentrating mechanism

scientific article published in February 2003

An optimization algorithm for a distributed-loop model of an avian urine concentrating mechanism

scientific article published on 20 June 2006

An optimization study of a mathematical model of the urine concentrating mechanism of the rat kidney

scientific article published on 3 November 2009

Autoregulation and conduction of vasomotor responses in a mathematical model of the rat afferent arteriole

scientific article

Bifurcation study of blood flow control in the kidney.

scientific article published on 5 March 2015

Bladder urine oxygen tension for assessing renal medullary oxygenation in rabbits: experimental and modeling studies.

scientific article published on 6 July 2016

Calcium dynamics underlying the myogenic response of the renal afferent arteriole

scientific article published on 30 October 2013

Cardiovascular benefits of SGLT2 inhibition in diabetes and chronic kidney diseases

scientific article published on 8 February 2018

Cell Volume Regulation in the Proximal Tubule of Rat Kidney : Proximal Tubule Cell Volume Regulation

scientific article

Conduction of feedback-mediated signal in a computational model of coupled nephrons

scientific article published on 19 March 2015

Control and modulation of fluid flow in the rat kidney

scientific article published on 09 October 2013

Countercurrent multiplication may not explain the axial osmolality gradient in the outer medulla of the rat kidney ⬇️

scientific article published on July 13, 2011

Dominant factors that govern pressure natriuresis in diuresis and antidiuresis: a mathematical model

scientific article

Drosophila morphogenesis: tissue force laws and the modeling of dorsal closure

scientific article

Dynamic contrast-enhanced quantitative susceptibility mapping with ultrashort echo time MRI for evaluating renal function.

scientific article

Effect of tubular inhomogeneities on feedback-mediated dynamics of a model of a thick ascending limb ⬇️

scientific article published on April 17, 2012

Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study

scientific article

Effects of pH and medullary blood flow on oxygen transport and sodium reabsorption in the rat outer medulla

scientific article

Expanding the scope of quantitative FRAP analysis

scientific article published on 15 October 2009

Feedback-mediated dynamics in a model of a compliant thick ascending limb

scientific article

Feedback-mediated dynamics in a model of coupled nephrons with compliant thick ascending limbs ⬇️

scientific article published on February 15, 2011

Fluid dilution and efficiency of Na+transport in a mathematical model of a thick ascending limb cell ⬇️

scientific article published on October 24, 2012

Functional implications of sexual dimorphism of transporter patterns along the rat proximal tubule: modeling and analysis

scientific article published on 30 May 2018

Functional implications of the sex differences in transporter abundance along the rat nephron: modeling and analysis

scientific article published on 30 September 2019

Functional implications of the three-dimensional architecture of the rat renal inner medulla

scientific article

Generation and phenotypic analysis of mice lacking all urea transporters

scientific article

How Do Kidneys Adapt to a Deficit or Loss in Nephron Number?

scientific article published on 01 May 2019

Hyperfiltration and inner stripe hypertrophy may explain findings by Gamble and coworkers.

scientific article

Impact of nitric oxide-mediated vasodilation on outer medullary NaCl transport and oxygenation ⬇️

scientific article published on July 11, 2012

Impact of nitric-oxide-mediated vasodilation and oxidative stress on renal medullary oxygenation: a modeling study

scientific article published on 14 October 2015

Impact of renal medullary three-dimensional architecture on oxygen transport

scientific article

Impacts of Active Urea Secretion into Pars Recta on Urine Concentration and Urea Excretion Rate.

scientific article published on September 2013

Impacts of nitric oxide and superoxide on renal medullary oxygen transport and urine concentration

scientific article published on 28 January 2015

Interface methods for biological and biomedical problems

scientific article published on 01 March 2012

Intraarterial Microdosing: A Novel Drug Development Approach, Proof-of-Concept PET Study in Rats

scientific article published on 27 August 2015

Isolated interstitial nodal spaces may facilitate preferential solute and fluid mixing in the rat renal inner medulla.

scientific article

Mathematical modeling of kidney transport

scientific article published on 12 July 2013

Mathematical modeling of renal hemodynamics in physiology and pathophysiology

scientific article published on 9 March 2015

Mathematical modeling of urea transport in the kidney

scientific article

Maximum urine concentrating capability in a mathematical model of the inner medulla of the rat kidney

scientific article

Mechanistic mathematical model of polarity in yeast ⬇️

scientific article published on March 21, 2012

Modeling Glucose Metabolism in the Kidney

scientific article

Modeling Sex Differences in the Renin Angiotensin System and the Efficacy of Antihypertensive Therapies

scientific article published on 13 February 2018

Modeling Transport and Flow Regulatory Mechanisms of the Kidney

scientific article published on July 2012

Modeling Vesicle Traffic Reveals Unexpected Consequences for Cdc42p-Mediated Polarity Establishment ⬇️

scientific article published on February 8, 2011

Modeling glucose metabolism and lactate production in the kidney

scientific article

Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition

scientific article published on 8 April 2015

Modeling the effects of positive and negative feedback in kidney blood flow control

scientific article published on 10 March 2016

Modulation of outer medullary NaCl transport and oxygenation by nitric oxide and superoxide

scientific article published on 17 August 2011

Multistability in tubuloglomerular feedback and spectral complexity in spontaneously hypertensive rats

scientific article published on 4 October 2005

Multistable dynamics mediated by tubuloglomerular feedback in a model of coupled nephrons

scientific article published on 10 February 2009

Network centrality analysis of eye-gaze data in autism spectrum disorder

scientific article published on 20 June 2019

Nitric oxide and superoxide transport in a cross section of the rat outer medulla. I. Effects of low medullary oxygen tension

scientific article

Nitric oxide and superoxide transport in a cross section of the rat outer medulla. II. Reciprocal interactions and tubulovascular cross talk

scientific article

Optimizing SGLT inhibitor treatment for diabetes with chronic kidney diseases

scientific article published on 28 June 2018

Oxygen transport in a cross section of the rat inner medulla: impact of heterogeneous distribution of nephrons and vessels

scientific article

Pathophysiological mechanisms underlying a rat model of triple whammy acute kidney injury

scientific article published on 27 July 2020

Predicted Effect of Circadian Clock Modulation of NHE3 of a Proximal Tubule Cell on Sodium Transport.

scientific article published on 14 March 2018

Predicted consequences of diabetes and SGLT inhibition on transport and oxygen consumption along a rat nephron.

scientific article published on 13 January 2016

Predicted effects of nitric oxide and superoxide on the vasoactivity of the afferent arteriole

scientific article

Recent advances in renal epithelial transport

scientific article published on 05 December 2018

Recent advances in renal hemodynamics: insights from bench experiments and computer simulations

scientific article

Recent advances in renal hypoxia: insights from bench experiments and computer simulations

scientific article published on 04 May 2016

Recent advances in sex differences in kidney function

scientific article published on 19 December 2018

Renal hemodynamics, function, and oxygenation during cardiac surgery performed on cardiopulmonary bypass: a modeling study

scientific article

Renal medullary and urinary oxygen tension during cardiopulmonary bypass in the rat.

scientific article published on 8 June 2016

Renal potassium handling in rats with subtotal nephrectomy: Modeling and Analysis.

scientific article published on 13 December 2017

Renal tubular solute transport and oxygen consumption: insights from computational models

scientific article published on 01 September 2018

Role of UTB urea transporters in the urine concentrating mechanism of the rat kidney

scientific article published in April 2007

Role of structural organization in the urine concentrating mechanism of an avian kidney

scientific article published in October 2005

Role of thin descending limb urea transport in renal urea handling and the urine concentrating mechanism

scientific article published on 17 August 2011

Role of three-dimensional architecture in the urine concentrating mechanism of the rat renal inner medulla

scientific article published on 21 May 2008

SGLT2 Inhibition in a Kidney with Reduced Nephron Number: Modeling and Analysis of Solute Transport and Metabolism.

scientific article published on 17 January 2018

Sex-Differences in Solute Transport Along the Nephrons: Effects of Na+ Transport Inhibition

scientific article published on 03 August 2020

Sex-specific computational models for blood pressure regulation in the rat

scientific article published on 10 February 2020

Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability

scientific article

Sex-specific long-term blood pressure regulation: Modeling and analysis

scientific article published on 10 November 2018

Signal transduction in a compliant short loop of Henle

scientific article

Signal transduction in a compliant thick ascending limb ⬇️

scientific article published on January 18, 2012

Solute and water transport along an inner medullary collecting duct undergoing peristaltic contractions

scientific article published on 17 July 2019

Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors

scientific article

Sweet Success? SGLT2 Inhibitors and Diabetes

scientific article published on 27 December 2017

Targeted delivery of solutes and oxygen in the renal medulla: role of microvessel architecture.

scientific article

The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats

scientific article published on 27 November 2020

The mammalian urine concentrating mechanism: hypotheses and uncertainties.

scientific article published on August 2009

Theoretical assessment of renal autoregulatory mechanisms

scientific article

Transfer Function Analysis of Dynamic Blood Flow Control in the Rat Kidney

scientific article published on 12 May 2016

Transport efficiency and workload distribution in a mathematical model of the thick ascending limb ⬇️

scientific article published on October 24, 2012

Tubular fluid flow and distal NaCl delivery mediated by tubuloglomerular feedback in the rat kidney

scientific article published on 26 March 2013

Tubuloglomerular feedback signal transduction in a short loop of henle

scientific article published on 6 August 2009

Two modes for concentrating urine in rat inner medulla.

scientific article

Understanding sex differences in long-term blood pressure regulation: insights from experimental studies and computational modeling

scientific article published on 15 March 2019

Urine concentrating mechanism: impact of vascular and tubular architecture and a proposed descending limb urea-Na+ cotransporter.

scientific article

Urine-concentrating mechanism in the inner medulla: function of the thin limbs of the loops of Henle

scientific article

Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers During the COVID-19 Pandemic: A Modeling Analysis

scientific article published on 08 October 2020

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