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List of works by Filip De Keyser

74-week follow-up of safety of infliximab in patients with refractory rheumatoid arthritis

scientific article

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort

scientific article published on 27 December 2010

An EULAR study group pilot study on reliability of simple capillaroscopic definitions to describe capillary morphology in rheumatic diseases

scientific article

Ankylosing spondylitis and bowel disease

scientific article

Antinuclear antibodies following infliximab treatment in patients with rheumatoid arthritis or spondylarthropathy

scientific article published in April 2003

Assessment of activity limitations with the health assessment questionnaire predicts the need for support measures in patients with rheumatoid arthritis: a multicenter observational study

scientific article

Assessment of sensitivity to change of the European Scleroderma Study Group activity index

scientific article published on 18 July 2016

Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis

scientific article

Automated indirect immunofluorescence antinuclear antibody analysis is a standardized alternative for visual microscope interpretation

scientific article

CARD15 variants determine a disturbed early response of monocytes to adherent-invasive Escherichia coli strain LF82 in Crohn's disease

scientific article published in June 2007

Cancer risk in immune-mediated inflammatory diseases (IMID).

scientific article published on 29 August 2013

Choice of Biologic Therapy for Patients with Rheumatoid Arthritis: The Infection Perspective ⬇️

scientific article published on February 1, 2011

Chronically inflamed synovium from spondyloarthropathy and rheumatoid arthritis investigated by protein expression profiling followed by tandem mass spectrometry

scientific article

Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins

scientific article published on 7 July 2010

Clues to pathogenesis of spondyloarthropathy derived from synovial fluid mononuclear cell gene expression profiles

scientific article

Comparison of the Belgian Rheumatoid Arthritis Disability Assessment and Health Assessment Questionnaires as Tools to Predict the Need for Support Measures in Patients with Rheumatoid Arthritis

scientific article published on 22 January 2016

Construction and psychometric properties of the Belgian Rheumatoid Arthritis Disability Assessment (BRADA) questionnaire: a new tool for the evaluation of activity limitations in patients with rheumatoid arthritis

scientific article

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy.

scientific article published on 25 August 2011

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy.

scientific article

DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment

scientific article

Decrease of disease activity under ineffective therapy in DMARD-naive patients with early rheumatoid arthritis: role of antibody profiles and carriage of the HLA shared epitope in predicting decrease of disease activity.

scientific article published on October 2007

Detection of major histocompatibility complex/human cartilage gp-39 complexes in rheumatoid arthritis synovitis as a specific and independent histologic marker

scientific article published in February 2004

Detection of specific antinuclear reactivities in patients with negative anti-nuclear antibody immunofluorescence screening tests.

scientific article published in December 2002

Diagnostic classification of spondylarthropathy and rheumatoid arthritis by synovial histopathology: a prospective study in 154 consecutive patients

scientific article published in September 2004

Diagnostic performance and predictive value of rheumatoid factor, anti-citrullinated peptide antibodies, and the HLA shared epitope for diagnosis of rheumatoid arthritis

scientific article published on 23 September 2004

Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays

scientific article

Differential expression and response to anti-TNFalpha treatment of infiltrating versus resident tissue macrophage subsets in autoimmune arthritis

scientific article published in May 2005

Dynamic T cell receptor clonotype changes in synovial tissue of patients with early rheumatoid arthritis: effects of treatment with cyclosporin A (Neoral).

scientific article published in March 2002

Effect of infliximab treatment on T cell cytokine responses in spondylarthropathy: comment on the article by Zou et al.

scientific article published in March 2004

Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis

scientific article

Erratum: Corrigendum: Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

scholarly article published in Nature Genetics

Factors influencing the occupational trajectory of patients with systemic sclerosis: a qualitative study

scientific article published on 20 March 2015

Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides

scientific article published in April 2005

Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity

scientific article published on January 2006

Fuchs' Uveitis Syndrome: No Longer a Syndrome?

scientific article published on 29 July 2015

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

scientific article

Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development

scientific article published in February 2014

Gut inflammation and spondyloarthropathies

scientific article

Gut inflammation in the spondyloarthropathies

scientific article

Histopathological cutaneous alterations in systemic sclerosis: a clinicopathological study ⬇️

scientific article published on February 28, 2011

Identification of citrullinated rheumatoid arthritis-specific epitopes in natural filaggrin relevant for antifilaggrin autoantibody detection by line immunoassay

scientific article

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy

scientific article

Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis

scientific article published in June 2006

Immune linkages between inflammatory bowel disease and spondyloarthropathies

scientific article

Immunomodulatory effects of etanercept on peripheral joint synovitis in the spondylarthropathies

scientific article

In pursuit of B-cell synovial autoantigens in rheumatoid arthritis: Confirmation of citrullinated fibrinogen, detection of vimentin, and introducing carbonic anhydrase as a possible new synovial autoantigen

scientific article published on 5 December 2006

Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy

scientific article

Infliximab in patients who have spondyloarthropathy: clinical efficacy, safety, and biological immunomodulation

scientific article

Infliximab, but not etanercept, induces IgM anti-double-stranded DNA autoantibodies as main antinuclear reactivity: biologic and clinical implications in autoimmune arthritis

scientific article published in July 2005

Involvement of matrix metalloproteinases and their inhibitors in peripheral synovitis and down-regulation by tumor necrosis factor alpha blockade in spondylarthropathy

scientific article published in September 2004

Localization of MHC class II/human cartilage glycoprotein-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies

scientific article (publication date: June 2003)

Longterm followup of rituximab therapy in patients with rheumatoid arthritis: results from the Belgian MabThera in Rheumatoid Arthritis registry

scientific article

Macrophages expressing the scavenger receptor CD163: a link between immune alterations of the gut and synovial inflammation in spondyloarthropathy

scientific article published in March 2002

Management of inflammatory bowel disease in pregnancy

scientific article

Nailfold Capillaroscopy and Clinical Applications in Systemic Sclerosis

scientific article published on 18 April 2016

Nailfold capillaroscopy for day-to-day clinical use: construction of a simple scoring modality as a clinical prognostic index for digital trophic lesions ⬇️

scientific article published on October 21, 2010

Nailfold capillaroscopy for prediction of novel future severe organ involvement in systemic sclerosis

scientific article published on 15 October 2013

Nailfold capillaroscopy in systemic lupus erythematosus: A systematic review and critical appraisal

scientific article published on 7 February 2018

Novel autoantibody markers for early and seronegative rheumatoid arthritis ⬇️

scientific article published on November 10, 2010

Optimal approaches to data collection and analysis of potential immune mediated disorders in clinical trials of new vaccines ⬇️

scientific article published on February 4, 2013

Prediction models for rheumatoid arthritis during diagnostic investigation: evaluation of combinations of rheumatoid factor, anti-citrullinated protein/peptide antibodies and the human leucocyte antigen-shared epitope

scientific article published on 13 July 2006

Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients ⬇️

scientific article published on July 24, 2012

Relevance of different results of different anti-double-stranded DNA assays in reporting clinical studies: comment on the article by Petri et al.

scientific article published in February 2014

Reliability of simple capillaroscopic definitions in describing capillary morphology in rheumatic diseases

scientific article published on 17 January 2018

Reliability of the qualitative and semiquantitative nailfold videocapillaroscopy assessment in a systemic sclerosis cohort: a two-centre study

scientific article

Reliability of the quantitative assessment of peripheral blood perfusion by laser speckle contrast analysis in a systemic sclerosis cohort

scientific article

Response to the commentary 'Pooled indices to measure rheumatoid arthritis activity: a good reflection of the physician's mind'.

scientific article published on January 2006

Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use.

scientific article

Screening for pulmonary arterial hypertension in an unselected prospective systemic sclerosis cohort

scientific article published on 11 May 2017

Serum levels of matrix metalloproteinase 3 and macrophage colony-stimulating factor 1 correlate with disease activity in ankylosing spondylitis

scientific article

Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease: attrition rate and evolution of disease activity

scientific article

Six-minute walk test in or out in evaluation of systemic sclerosis patients?

scientific article

Six-minute walk test in systemic sclerosis: A systematic review and meta-analysis

scientific article

Specific Antinuclear Antibody Level Changes after B Cell Depletion Therapy in Systemic Sclerosis Are Associated with Improvement of Skin Thickening

scientific article published in January 2016

Specific anti-nuclear antibodies in systemic sclerosis patients with and without skin involvement: an extended methodological approach

scientific article published on 17 February 2011

Spondyloarthropathies

scientific article published in July 2007

Structure-modifying capacity of anti-tumour necrosis factor-alpha therapy in ankylosing spondylitis

scientific article

Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis

scientific article

Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity

scientific article published in August 2005

Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis

scientific article published on 5 February 2009

Ten-year followup of infliximab therapy in rheumatoid arthritis patients with severe, longstanding refractory disease: a cohort study

scientific article published in June 2014

The Association of Illness Perceptions with Physical and Mental Health in Systemic Sclerosis Patients: An Exploratory Study ⬇️

scientific article published on November 11, 2011

The Belgian MIRA (MabThera In Rheumatoid Arthritis) registry: clues for the optimization of rituximab treatment strategies

scientific article

The heart and pulmonary arterial hypertension in systemic sclerosis

scientific article published on 5 February 2016

The histopathology of spondyloarthropathy

scientific article published on February 2004

The influence of ageing on the development and management of rheumatoid arthritis

scientific article published on 18 June 2013

The integration of the detection of systemic sclerosis-associated antibodies in a routine laboratory setting: comparison of different strategies

scientific article published in November 2013

Tumor necrosis factor alpha blockade treatment down-modulates the increased systemic and local expression of Toll-like receptor 2 and Toll-like receptor 4 in spondylarthropathy

scientific article published in July 2005

Tumor necrosis factor-alpha blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification?

scientific article

Two years follow-up of an open-label pilot study of treatment with rituximab in patients with early diffuse cutaneous systemic sclerosis

scientific article published on 11 September 2017

Two-year Results of an Open Pilot Study of a 2-treatment Course with Rituximab in Patients with Early Systemic Sclerosis with Diffuse Skin Involvement ⬇️

scientific article published on November 1, 2012

Vaccinations in patients with immune-mediated inflammatory diseases

scientific article

Work participation and work transition in patients with systemic sclerosis: a cross-sectional study ⬇️

scientific article published on October 4, 2011

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