List of works - Alexis Broisat

99mTc-A1 as a Novel Imaging Agent Targeting Mesothelin-Expressing Pancreatic Ductal Adenocarcinoma

scientific article published on 10 October 2019

99mTc-cAbVCAM1-5 imaging is a sensitive and reproducible tool for the detection of inflamed atherosclerotic lesions in mice

scientific article published on 25 August 2014

A proliferation-inducing ligand-mediated anti-inflammatory response of astrocytes in multiple sclerosis

scientific article published on 04 February 2019

A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy.

scientific article published on 26 March 2013

Assessing low levels of mechanical stress in aortic atherosclerotic lesions from apolipoprotein E-/- mice--brief report

scientific article published on 10 March 2011

Assessment of non-reperfused and reperfused myocardial infarction using diffusible or deposited radiolabelled perfusion imaging agents.

scientific article published on 27 September 2006

Biodistribution, Stability, and Blood Distribution of the Cell Penetrating Peptide Maurocalcine in Mice.

scientific article

Diagnostic value of stress thallium-201/rest technetium-99m-sestamibi sequential dual isotope high-speed myocardial perfusion imaging for the detection of haemodynamically relevant coronary artery stenosis

scientific article published on 29 January 2018

Early reduced dopaminergic tone mediated by D3 receptor and dopamine transporter in absence epileptogenesis

scientific article published on 19 September 2019

Effects of mechanical properties and atherosclerotic artery size on biomechanical plaque disruption - mouse vs. human.

scientific article

Elucidating atherosclerotic vulnerable plaque rupture by modeling cross substitution of ApoE-/- mouse and human plaque components stiffnesses

scientific article published on 11 October 2011

Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection.

scientific article published on 20 November 2017

Equivocal usefulness of FDG for the noninvasive imaging of abdominal aortic aneurysms

scientific article

Evaluation of Antiatherogenic Properties of Ezetimibe Using 3H-Labeled Low-Density-Lipoprotein Cholesterol and 99mTc-cAbVCAM1-5 SPECT in ApoE-/- Mice Fed the Paigen Diet

scientific article published on 9 March 2017

Evaluation of Imaging Strategy to Optimize and Improve Outcome of Transcatheter Aortic Valvular Implantation.

scientific article published on 31 July 2017

First magnetic resonance coronary artery imaging of bioresorbable vascular scaffold in-patient

scientific article published on 12 December 2014

From Malignant Progression to Therapeutic Targeting: Current Insights of Mesothelin in Pancreatic Ductal Adenocarcinoma

scientific article published on 06 June 2020

From in vitro evaluation to human postmortem pre-validation of a radiopaque and resorbable internal biliary stent for liver transplantation applications

scientific article published on 31 January 2020

Identifying the leukocyte uptake pattern of inflammation imaging agents: Current limitations and potential impact

scientific article published on 10 December 2019

Improved Detection of Molecular Markers of Atherosclerotic Plaques Using Sub-Millimeter PET Imaging

scientific article published on 16 April 2020

In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer

scientific article published on 23 July 2019

In Vivo Molecular Imaging of Atherosclerotic Lesions in ApoE−/− Mice Using VCAM-1–Specific, 99mTc-Labeled Peptidic Sequences ⬇️

scientific article published on May 29, 2013

In vivo molecular imaging of myocardial angiogenesis using the αvβ3 integrin-targeted tracer 99mTc-RAFT-RGD

scientific article published on 20 January 2010

Know the strengths and weaknesses of ischemia tests to guide the therapeutic strategy of a patient with multi-vessel disease

scientific article published on 14 January 2016

Mapping elasticity moduli of atherosclerotic plaque in situ via atomic force microscopy

scientific article published on 04 February 2011

Mapping of brain tissue hematocrit in glioma and acute stroke using a dual autoradiography approach.

scientific article

Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p

scientific article published on 12 January 2007

Multiscale investigation of USPIO nanoparticles in atherosclerotic plaques and their catabolism and storage in vivo

scientific article published on 11 September 2015

Myocardial uptake of 7'-(Z)-[(123)I]iodorotenone during vasodilator stress in dogs with critical coronary stenoses

scientific article

Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions

scientific article published on March 2012

Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis

scientific article published on 17 October 2018

Nanobody-coupled microbubbles as novel molecular tracer

scientific article

Novel SPECT perfusion imaging agents with improved myocardial or liver kinetics: Experimental studies and the need for clinical evaluation ⬇️

scientific article published on 01 October 2010

Periaortic brown adipose tissue as a major determinant of [¹⁸F]-fluorodeoxyglucose vascular uptake in atherosclerosis-prone, apoE-/- mice

scientific article

Preclinical characterization of a novel radiolabeled analog of practolol for the molecular imaging of myocardial β-adrenoceptor density

scientific article published on 30 May 2014

Preclinical evaluation of novel mesothelin-specific ligands for SPECT imaging of Triple Negative Breast Cancer.

scientific article published on 23 March 2018

Prospective diagnostic performance of semiconductor SPECT myocardial perfusion imaging: wall thickening analysis reduces the need for an additional prone acquisition

scientific article published on 18 July 2019

Radiometal-labeled anti-VCAM-1 nanobodies as molecular tracers for atherosclerosis - impact of radiochemistry on pharmacokinetics

scientific article published on 01 February 2019

Reduction in myocardial infarct size at 48 hours after brief intravenous infusion of ATL-146e, a highly selective adenosine A2A receptor agonist

scientific article

SPECT myocardial ischemia in the absence of obstructive CAD: Contribution of the invasive assessment of microvascular dysfunction.

scientific article published on 5 December 2017

Stress thallium-201/rest technetium-99m sequential dual-isotope high-speed myocardial perfusion imaging validation versus invasive coronary angiography

scientific article published on 8 November 2014

Suboptimal performance of cardiovascular magnetic resonance imaging for the assessment of myocardial viability at the early phase of an acute coronary syndrome: Usefulness of SPECT myocardial perfusion imaging

scientific article published on 26 June 2018

Sympathetic cardiac function in early sepsis: Noninvasive evaluation with [123I]-meta-iodobenzylguanidine (123I-MIBG) in vivo SPECT imaging

scientific article published on 29 August 2016

Targeted radionuclide therapy with RAFT-RGD radiolabelled with (90)Y or (177)Lu in a mouse model of αvβ3-expressing tumours.

scientific article published on 28 August 2014

Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

scientific article published on 22 January 2016

The in vivo cardiac kinetics of Tc-99m N-NOET are accelerated in obese, hyperlipidemic Zucker rats

scientific article published on 01 January 2006

Translating Molecular Imaging of the Vulnerable Plaque-a Vulnerable Project?

scientific article published on 27 November 2017

Ultrasmall rigid particles as multimodal probes for medical applications

scientific article published on 04 November 2011

Ultrasound Molecular Imaging of Atherosclerosis With Nanobodies: Translatable Microbubble Targeting Murine and Human VCAM (Vascular Cell Adhesion Molecule) 1

scientific article published on 10 October 2019

List of works by Alexis Broisat

99mTc-A1 as a Novel Imaging Agent Targeting Mesothelin-Expressing Pancreatic Ductal Adenocarcinoma

99mTc-cAbVCAM1-5 imaging is a sensitive and reproducible tool for the detection of inflamed atherosclerotic lesions in mice

A proliferation-inducing ligand-mediated anti-inflammatory response of astrocytes in multiple sclerosis

A safe bacterial microsyringe for in vivo antigen delivery and immunotherapy.

Assessing low levels of mechanical stress in aortic atherosclerotic lesions from apolipoprotein E-/- mice--brief report

Assessment of non-reperfused and reperfused myocardial infarction using diffusible or deposited radiolabelled perfusion imaging agents.

Biodistribution, Stability, and Blood Distribution of the Cell Penetrating Peptide Maurocalcine in Mice.

Diagnostic value of stress thallium-201/rest technetium-99m-sestamibi sequential dual isotope high-speed myocardial perfusion imaging for the detection of haemodynamically relevant coronary artery stenosis

Early reduced dopaminergic tone mediated by D3 receptor and dopamine transporter in absence epileptogenesis

Effects of mechanical properties and atherosclerotic artery size on biomechanical plaque disruption - mouse vs. human.

Elucidating atherosclerotic vulnerable plaque rupture by modeling cross substitution of ApoE-/- mouse and human plaque components stiffnesses

Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection.

Equivocal usefulness of FDG for the noninvasive imaging of abdominal aortic aneurysms

Evaluation of Antiatherogenic Properties of Ezetimibe Using 3H-Labeled Low-Density-Lipoprotein Cholesterol and 99mTc-cAbVCAM1-5 SPECT in ApoE-/- Mice Fed the Paigen Diet

Evaluation of Imaging Strategy to Optimize and Improve Outcome of Transcatheter Aortic Valvular Implantation.

First magnetic resonance coronary artery imaging of bioresorbable vascular scaffold in-patient

From Malignant Progression to Therapeutic Targeting: Current Insights of Mesothelin in Pancreatic Ductal Adenocarcinoma

From in vitro evaluation to human postmortem pre-validation of a radiopaque and resorbable internal biliary stent for liver transplantation applications

Identifying the leukocyte uptake pattern of inflammation imaging agents: Current limitations and potential impact

Improved Detection of Molecular Markers of Atherosclerotic Plaques Using Sub-Millimeter PET Imaging

In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer

In Vivo Molecular Imaging of Atherosclerotic Lesions in ApoE−/− Mice Using VCAM-1–Specific, 99mTc-Labeled Peptidic Sequences ⬇️

In vivo molecular imaging of myocardial angiogenesis using the αvβ3 integrin-targeted tracer 99mTc-RAFT-RGD

Know the strengths and weaknesses of ischemia tests to guide the therapeutic strategy of a patient with multi-vessel disease

Mapping elasticity moduli of atherosclerotic plaque in situ via atomic force microscopy

Mapping of brain tissue hematocrit in glioma and acute stroke using a dual autoradiography approach.

Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p

Multiscale investigation of USPIO nanoparticles in atherosclerotic plaques and their catabolism and storage in vivo

Myocardial uptake of 7'-(Z)-[(123)I]iodorotenone during vasodilator stress in dogs with critical coronary stenoses

Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions

Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis

Nanobody-coupled microbubbles as novel molecular tracer

Novel SPECT perfusion imaging agents with improved myocardial or liver kinetics: Experimental studies and the need for clinical evaluation ⬇️

Periaortic brown adipose tissue as a major determinant of [¹⁸F]-fluorodeoxyglucose vascular uptake in atherosclerosis-prone, apoE-/- mice

Preclinical characterization of a novel radiolabeled analog of practolol for the molecular imaging of myocardial β-adrenoceptor density

Preclinical evaluation of novel mesothelin-specific ligands for SPECT imaging of Triple Negative Breast Cancer.

Prospective diagnostic performance of semiconductor SPECT myocardial perfusion imaging: wall thickening analysis reduces the need for an additional prone acquisition

Radiometal-labeled anti-VCAM-1 nanobodies as molecular tracers for atherosclerosis - impact of radiochemistry on pharmacokinetics

Reduction in myocardial infarct size at 48 hours after brief intravenous infusion of ATL-146e, a highly selective adenosine A2A receptor agonist

SPECT myocardial ischemia in the absence of obstructive CAD: Contribution of the invasive assessment of microvascular dysfunction.

Stress thallium-201/rest technetium-99m sequential dual-isotope high-speed myocardial perfusion imaging validation versus invasive coronary angiography

Suboptimal performance of cardiovascular magnetic resonance imaging for the assessment of myocardial viability at the early phase of an acute coronary syndrome: Usefulness of SPECT myocardial perfusion imaging

Sympathetic cardiac function in early sepsis: Noninvasive evaluation with [123I]-meta-iodobenzylguanidine (123I-MIBG) in vivo SPECT imaging

Targeted radionuclide therapy with RAFT-RGD radiolabelled with (90)Y or (177)Lu in a mouse model of αvβ3-expressing tumours.

Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

The in vivo cardiac kinetics of Tc-99m N-NOET are accelerated in obese, hyperlipidemic Zucker rats

Translating Molecular Imaging of the Vulnerable Plaque-a Vulnerable Project?

Ultrasmall rigid particles as multimodal probes for medical applications

Ultrasound Molecular Imaging of Atherosclerosis With Nanobodies: Translatable Microbubble Targeting Murine and Human VCAM (Vascular Cell Adhesion Molecule) 1