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List of works by Sergiu Pasca

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

scientific article published on 26 July 2016

A framework for the investigation of rare genetic disorders in neuropsychiatry

scientific article published on 23 September 2019

A human cellular model of amyotrophic lateral sclerosis

scientific article published on 01 March 2018

A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT.

scientific article

Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome

scientific article published on 23 December 2019

Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome.

scientific article

Approach to the Adult Acute Lymphoblastic Leukemia Patient

scientific article published on 06 August 2019

Assembling human brain organoids

scientific article published on 01 January 2019

Assembly of functionally integrated human forebrain spheroids

scientific article published on 26 April 2017

Basic knowledge on BCR-ABL1-positive extracellular vesicles

scientific article published on 09 April 2020

Behavioral effects of corpus callosum transection and environmental enrichment in adult rats.

scientific article published on 9 June 2006

Building Models of Brain Disorders with Three-Dimensional Organoids

article

Building three-dimensional human brain organoids

scientific article published on 28 March 2018

Cell diversity in the human cerebral cortex: from the embryo to brain organoids

scientific article published on 30 April 2019

Chimeric Antigen Receptor T-Cells for the Treatment of B-Cell Acute Lymphoblastic Leukemia.

scientific article published on 19 February 2018

Chromatin accessibility dynamics in a model of human forebrain development

scientific article published on 01 January 2020

Circulating microRNA-194 and microRNA-1228 Could Predict Colon Cancer Proliferation via Phospho S6 Modulation

scientific article published on 09 September 2020

Correction: Genetically enhanced T lymphocytes and the intensive care unit

scientific article published on 10 August 2018

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain

scientific article published on February 2016

Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures

scientific article published on 28 January 2019

Engineering a Genetically Encoded Magnetic Protein Crystal

scientific article published on 25 September 2019

Exosome-carried microRNA-based signature as a cellular trigger for the evolution of chronic lymphocytic leukemia into Richter syndrome

scientific article published on 21 September 2018

Fibroblast dynamics as an in vitro screening platform for anti-fibrotic drugs in primary myelofibrosis

scientific article

Generating human neurons in vitro and using them to understand neuropsychiatric disease.

scientific article published on 23 June 2014

Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells

scientific article published on 03 December 2020

Genetically enhanced T lymphocytes and the intensive care unit.

scientific article

Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals

scientific article published on 19 March 2020

High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism.

scientific article

How collaboration between bioethicists and neuroscientists can advance research

Human 3D cellular model of hypoxic brain injury of prematurity

scientific article published on 06 May 2019

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells.

scientific article published on August 2017

Let's Talk About BiTEs and Other Drugs in the Real-Life Setting for B-Cell Acute Lymphoblastic Leukemia

scientific article published on 20 December 2019

Long-term maturation of human cortical organoids matches key early postnatal transitions

scientific article published on 22 February 2021

Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment

scientific article published on 20 May 2019

Mental Fatigue Evaluation of Surgical Teams during a Regular Workday in a High-Volume Tertiary Healthcare Center

scientific article published on 17 January 2020

MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis.

scientific article published in August 2017

Minimal residual disease in chronic lymphocytic leukemia: A consensus paper that presents the clinical impact of the presently available laboratory approaches

scientific article published on 25 May 2018

Neural Differentiation in the Third Dimension: Generating a Human Midbrain.

scientific article published in August 2016

Neuronal defects in a human cellular model of 22q11.2 deletion syndrome

scientific article published on 28 September 2020

Next-generation sequencing-based characterization of the invasion by anatomical contiguity in a primary osseous diffuse large B-cell lymphoma. Correlation between the genetic profile of the malignancy and the clinical outcome of the patient

scientific article published on 23 November 2018

Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring.

scientific article published on 21 February 2017

One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders

scientific article published in October 2009

Organoid and Assembloid Technologies for Investigating Cellular Crosstalk in Human Brain Development and Disease

scientific article published on 23 December 2019

Persistent Basophilia May Suggest an "Accelerated Phase" in the Evolution of CALR-Positive Primary Myelofibrosis Toward Acute Myeloid Leukemia

scientific article published on 06 September 2019

Personalized Human Cortical Spheroids.

scientific article published in April 2016

Polarizing brain organoids

scientific article published on 01 April 2019

Primate cell fusion disentangles gene regulatory divergence in neurodevelopment

scientific article published on 17 March 2021

Reliability of human cortical organoid generation

scientific article published on 20 December 2018

Research and training in autism spectrum disorder to catalyze the next genomic and neuroscience revolutions

scientific article published on 29 June 2020

Role of Key Micronutrients from Nutrigenetic and Nutrigenomic Perspectives in Cancer Prevention

scientific article published on 18 June 2019

SERS-based differential diagnosis between multiple solid malignancies: breast, colorectal, lung, ovarian and oral cancer

scientific article published on 02 August 2019

Serum paraoxonase 1 activities and homocysteinemia in hemodialysis patients.

scientific article published in January 2008

The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C

scientific article published on 01 December 2021

The Zika threat to the periphery

scientific article published on August 2017

The hidden biology of the human brain

scientific article published on 01 November 2019

The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression.

scientific article published on 19 January 2018

The use of rotation to fentanyl in cancer-related pain

scientific article

Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons

scientific article published on 13 January 2013

Transient leukemia of Down syndrome

scientific article published on 21 June 2019

Vomiting is not an adaption for glaucoma (and Darwinian medicine is difficult)

scientific article published on 29 May 2008

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