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List of works by Beth Levine

4th International Symposium on Autophagy: exploiting the frontiers of autophagy research

scientific article published on 4 March 2007

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease.

scientific article published on 14 August 2017

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

scientific article

A comprehensive glossary of autophagy-related molecules and processes

scientific article published on 16 May 2010

A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

scientific article

A surface groove essential for viral Bcl-2 function during chronic infection in vivo

scientific article

Age-dependent resistance to lethal alphavirus encephalitis in mice: analysis of gene expression in the central nervous system and identification of a novel interferon-inducible protective gene, mouse ISG12.

scientific article

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

scientific article published on 25 October 2012

An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis

scientific article published on 01 June 2018

Analysis of the role of autophagy in replication of herpes simplex virus in cell culture

scientific article

Author Correction: Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice

scientific article published in Nature

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation

scientific article

Autophagy and Longevity: Lessons from C. elegans ⬇️

scientific article published on January 1, 2010

Autophagy and Viruses: Adversaries or Allies? ⬇️

scientific article published on January 31, 2013

Autophagy and cancer

scientific article published in Nature

Autophagy and cancer metabolism

scientific article published on January 2014

Autophagy and innate immunity: triggering, targeting and tuning

scientific article published on 18 April 2010

Autophagy and the cell biology of age-related disease

scientific article published on 26 November 2018

Autophagy balances inflammation in innate immunity

scientific article published on 22 November 2017

Autophagy fights disease through cellular self-digestion

scientific article (publication date: 28 February 2008)

Autophagy gene-dependent clearance of apoptotic cells during embryonic development

scientific article

Autophagy genes are essential for dauer development and life-span extension in C. elegans

scientific article (publication date: 5 September 2003)

Autophagy genes function in apoptotic cell corpse clearance duringC. elegansembryonic development ⬇️

scientific article published on October 29, 2012

Autophagy genes in immunity

scientific article published on May 2009

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

scholarly article

Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans

scientific article

Autophagy in C. elegans

scientific article published on 24 August 2009

Autophagy in Human Diseases

scientific article published on 01 October 2020

Autophagy in Human Health and Disease ⬇️

scientific article published on May 9, 2013

Autophagy in cell death: an innocent convict?

scientific article published in December 2006

Autophagy in cellular growth control

scientific article published on 22 January 2010

Autophagy in development, tumor suppression, and innate immunity.

scientific article

Autophagy in immunity and inflammation

scientific article

Autophagy in malignant transformation and cancer progression

scientific article

Autophagy in the Pathogenesis of Disease

scientific article (publication date: 11 January 2008)

Autophagy is an adaptive response in desmin-related cardiomyopathy

scholarly article

Autophagy is essential for cardiac morphogenesis during vertebrate development

scientific article published on 14 January 2014

Autophagy is required for G₁/G₀ quiescence in response to nitrogen starvation in Saccharomyces cerevisiae

scientific article published on 12 August 2014

Autophagy is required for dietary restriction-mediated life span extension in C. elegans

scientific article published on 6 September 2007

Autophagy modulation as a potential therapeutic target for diverse diseases ⬇️

scientific article published on September 1, 2012

Autophagy protects against Sindbis virus infection of the central nervous system

scientific article published in February 2010

Autophagy regulates programmed cell death during the plant innate immune response

scientific article published in May 2005

Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fuel advances in biomedical research

scientific article published on 30 December 2016

Autophagy, Immunity, and Microbial Adaptations

scientific article

Autophagy, antiviral immunity, and viral countermeasures

scientific article

Autophagy: Snapshot of the network

scientific article published on July 2010

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

scientific article

BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy

scientific article published in January 2015

BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy

scientific article published on 20 February 2017

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

scientific article (publication date: 23 September 2005)

Bcl-2 family members: dual regulators of apoptosis and autophagy

scientific article published on 12 May 2008

Bcl-2 inhibition of autophagy: a new route to cancer?

scientific article

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

scientific article

Beclin 2 negatively regulates innate immune signaling and tumor development

scientific article published on 31 August 2020

Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology

scientific article

Beclin-1-Dependent Autophagy Protects the Heart During Sepsis

scientific article published on 01 November 2018

Beth Levine receives the 2014 ASCI/Stanley J. Korsmeyer Award

scientific article published on April 2014

Biological Functions of Autophagy Genes: A Disease Perspective

scientific article published on 01 January 2019

Calcipotriol Induces Autophagy in HeLa Cells and Keratinocytes ⬇️

scientific article published on January 13, 2011

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

scientific article published on July 2016

Cardiac autophagy is a maladaptive response to hemodynamic stress

scientific article published in July 2007

Cell Penetration Profiling Using the Chloroalkane Penetration Assay

scientific article published on 31 August 2018

Ceramide-induced autophagy: to junk or to protect cells?

scientific article published on 10 May 2009

Chikungunya virus-induced autophagy delays caspase-dependent cell death

scientific article

Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy

scientific article published on 27 July 2012

Closing the loop

scientific article published on 01 November 2016

Collecting for the Platypus—Acquisition and Collection Management in the Arnold Library

Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens

scientific article

Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitis

scientific article

Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection

scientific article published on August 2002

CuATSM efficacy is independently replicated in a SOD1 mouse model of ALS while unmetallated ATSM therapy fails to reveal benefits

scientific article published on 12 March 2017

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis

scientific article published on 2 June 2015

Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated with Estrogen Receptor-Negative Subtypes and Poor Prognosis.

scientific article

Development of autophagy inducers in clinical medicine

scientific article

Development. Inheriting maternal mtDNA.

scientific article

Dexpramipexole is ineffective in two models of ALS related neurodegeneration

scientific article

Discovery of new C3aR ligands. Part 2: amino-piperidine derivatives

scientific article published on 10 April 2007

Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice

scientific article published in Nature

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

scientific article published in March 2007

Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy.

scientific article

Does Autophagy Mediate Cardiac Myocyte Death During Stress?

scientific article published on September 2016

Downregulation of autophagy is associated with severe ischemia-reperfusion-induced acute kidney injury in overexpressing C-reactive protein mice.

scientific article published on 8 September 2017

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure.

scientific article published on 25 February 2016

Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

scientific article published on 14 October 2008

EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance

scientific article

Eating oneself and uninvited guests: autophagy-related pathways in cellular defense

scientific article

Emerging functions of the Fanconi anemia pathway at a glance

scientific article published on August 2017

Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis.

scientific article published on 29 February 2016

Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction

scientific article published in 2021

Erratum: Corrigendum: Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

scientific article published in November 2013

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Exercise induces autophagy in peripheral tissues and in the brain

scientific article published on 15 August 2012

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

scientific article

Fanconi Anemia Proteins Function in Mitophagy and Immunity

scientific article

GABARAP-mediated targeting of PI4K2A/PI4KIIα to autophagosomes regulates PtdIns4P-dependent autophagosome-lysosome fusion

scientific article published on 21 September 2015

GABARAPs regulate PI4P-dependent autophagosome:lysosome fusion

scientific article published on 18 May 2015

GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex

scientific article published on 23 November 2020

Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis

scientific article published on 16 September 2016

Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS.

scientific article published on 19 August 2015

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

HIV and CXCR4 in a kiss of autophagic death

scientific article published on August 2006

HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein

scientific article published on March 2007

High Throughput Screens to Identify Autophagy Inducers that Function by Disrupting Beclin 1/Bcl-2 Binding.

scientific article

How shall I eat thee?

scientific article published on 15 May 2007

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

scientific journal article

Identification of a candidate therapeutic autophagy-inducing peptide

scientific journal article

Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo

scientific article

Identification of secreted proteins that reflect autophagy dynamics within tumor cells

scientific article

Image-based genome-wide siRNA screen identifies selective autophagy factors

scientific article

Increased autophagy blocks HER2-mediated breast tumorigenesis

scientific article published on 2 April 2018

Interaction between the autophagy protein Beclin 1 and Na+,K+-ATPase during starvation, exercise, and ischemia

scientific article published on 16 January 2020

Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria ⬇️

scientific article published on June 12, 2013

Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation

scientific article

Metabolic control of autophagy

scientific article

Microfold Cells Actively Translocate Mycobacterium tuberculosis to Initiate Infection.

scientific article published on 20 July 2016

Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy

scientific article

Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11

scientific article

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Novel functions of Fanconi anemia proteins in selective autophagy and inflammation

scientific article published on 30 July 2016

PKR-dependent autophagic degradation of herpes simplex virus type 1.

scientific article published on 15 January 2006

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis

scientific article

Peroxisomal protein PEX13 functions in selective autophagy.

scientific article published on 8 November 2016

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

scientific article

Primary Neurons and Differentiated NSC-34 Cells Are More Susceptible to Arginine-Rich ALS Dipeptide Repeat Protein-Associated Toxicity than Non-Differentiated NSC-34 and CHO Cells ⬇️

scientific article published on 11 December 2019

Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor

scientific article published on 14 December 2016

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

scientific article published on 17 August 2018

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

scientific article

Protective Effect of SMAD-Specific E3 Ubiquitin Protein Ligase 1 in Alcoholic Steatohepatitis in Mice

scientific article published on 12 September 2019

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly

scientific article

Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway

scientific article

Response by Shirakabe et al to Letter Regarding Article, "Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure".

scientific article published on August 2016

Risk-adapted autologous stem cell transplantation with adjuvant dexamethasone +/- thalidomide for systemic light-chain amyloidosis: results of a phase II trial.

scientific article published in October 2007

Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy

scientific article

SOD1-positive aggregate accumulation in the CNS predicts slower disease progression and increased longevity in a mutant SOD1 mouse model of ALS

scientific article published on 30 April 2019

Selective autophagy and viruses ⬇️

scientific article published on March 1, 2011

SnapShot: Macroautophagy

scientific article

Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein

scientific article

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

scientific article published on 12 February 2020

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition

scientific article

Targeting  -Herpesvirus 68 Bcl-2-mediated Down-regulation of Autophagy

scientific article

The Autophagy-Related Beclin-1 Protein Requires the Coiled-Coil and BARA Domains To Form a Homodimer with Submicromolar Affinity.

scientific article published on 29 November 2017

The Beclin 1 interactome

scientific article published on 22 January 2010

The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels

scientific article

The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense

scientific article published on 14 December 2016

The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense

scientific article published in September 2017

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

scientific article

The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

scientific article published on 17 April 2005

The role of autophagy in mammalian development: cell makeover rather than cell death

scientific article published on September 2008

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

scientific article

The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance

scientific article published on 05 January 2020

To be or not to be? How selective autophagy and cell death govern cell fate

scientific article

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

scientific article

Unraveling the role of autophagy in cancer

scientific article published on 29 April 2006

Unveiling the roles of autophagy in innate and adaptive immunity

scientific article published on October 2007

Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury

scientific article published on 04 May 2020

Viruses and autophagy

scientific article (publication date: November 2009)

iScreen: Image-Based High-Content RNAi Screening Analysis Tools

scientific article published on 29 December 2014

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy

scientific article published on 5 September 2017

p53: The Janus of autophagy?

scientific article published on June 2008

αKlotho Mitigates Progression of AKI to CKD through Activation of Autophagy

scientific article published on 23 December 2015

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