List of works by Laura Soucek

A spotlight on cancer researchers in Spain: new paradigms and disruptive ideas

scientific article published on 09 August 2019

Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/beta-catenin pathway activation

scientific article

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

scientific article

BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC.

scientific article published on 10 April 2018

Bcl-xL gain of function and p19 ARF loss of function cooperate oncogenically with Myc in vivo by distinct mechanisms

scientific article published in August 2006

Biophysical characterization of the b-HLH-LZ of ΔMax, an alternatively spliced isoform of Max found in tumor cells: Towards the validation of a tumor suppressor role for the Max homodimers

scientific article

Blocking Myc to Treat Cancer: Reflecting on Two Decades of Omomyc

scientific article published on 04 April 2020

Drugging the 'undruggable' cancer targets

scientific article published on 23 June 2017

Editorial overview: Peptides in cancer

scientific article published on 28 June 2019

Endogenous Myc maintains the tumor microenvironment

scientific article

Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma

scientific article published on 06 November 2019

Finding MYCure

scientific article published on 20 June 2019

Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma

scientific article published on 01 December 2021

Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation

scientific article published on 18 April 2016

Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.

scientific article published in April 2015

Ibrutinib repurposing: from B-cell malignancies to solid tumors

scientific article published on 10 June 2016

Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo

scientific article published on 10 January 2019

Inhibition of Myc effectively targets KRAS mutation-positive lung cancer expressing high levels of Myc

scientific article published on October 1, 2010

Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

scientific article published on March 2013

Interrogating open issues in cancer medicine with patient-derived xenografts

scientific article published on 15 September 2017

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

scientific article published on 20 January 2017

Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy

scientific article published on 01 March 2019

Live or Die: Choice Mechanisms in Stressed Cells

scientific article published on 8 October 2015

MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype

scientific article published on 15 January 2020

MYC, MYCL, and MYCN as therapeutic targets in lung cancer

scientific article published on 13 February 2020

Making decisions through Myc.

scientific article

Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors

scientific article published on 30 September 2007

Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma

scientific article published on November 2011

Modelling Myc inhibition as a cancer therapy

scientific article

Myc and Ras, the Bonnie and Clyde of immune evasion

scientific article published on 01 April 2018

Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis.

scientific article

Myc-Is this the oncogene from Hell?

scientific article

NGF-dependent and tissue-specific transcription of vgf is regulated by a CREB-p300 and bHLH factor interaction

scientific article (publication date: 2 January 2002)

Omomyc, a potential Myc dominant negative, enhances Myc-induced apoptosis.

scientific article published on June 2002

Pancreatic cancer heterogeneity and response to Mek inhibition

scientific article published on 5 June 2017

Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis.

scientific article

Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology.

scientific article published on 8 November 2011

Strategies to Inhibit Myc and Their Clinical Applicability

scientific article

Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein

scientific article published on 22 April 2020

Tamoxifen administration to mice.

scientific article published on 2 March 2015

Temporal dissection of p53 function in vitro and in vivo

scientific article published on 29 May 2005

The Estrogen Receptor Fusion System in Mouse Models: A Reversible Switch

scientific article published on 02 March 2015

The Myc world within reach

scientific article published in January 2013

The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy

scientific article

The effect of environmental chemicals on the tumor microenvironment

scientific article

The ups and downs of Myc biology

scientific article published on 03 December 2009

Tumor microenvironment: becoming sick of Myc.

scientific article published on 28 October 2011

c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis

scientific article (publication date: 28 August 2003)

Paulina is supported by:

About Paulina

Help