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List of works by Bernard Roizman

A DNA fragment of Herpes simplex 2 and its transcription in human cervical cancer tissue

scientific article published on December 1972

A generalized technique for deletion of specific genes in large genomes: alpha gene 22 of herpes simplex virus 1 is not essential for growth.

scientific article

A herpes simplex virus 1 US11-expressing cell line is resistant to herpes simplex virus infection at a step in viral entry mediated by glycoprotein D

scientific article published on May 1994

A noninverting genome of a viable herpes simplex virus 1: presence of head-to-tail linkages in packaged genomes and requirements for circularization after infection

scientific article published on February 1985

A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infection

scientific article

A novel herpes simplex virus 1 gene, UL43.5, maps antisense to the UL43 gene and encodes a protein which colocalizes in nuclear structures with capsid proteins

scientific article published in May 1996

A post-alpha gene function turns off the capacity of a host protein to bind DNA in cells infected with herpes simplex virus 1.

scientific article published on March 1984

A single amino acid substitution in the cyclin D binding domain of the infected cell protein no. 0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate

scientific article

Abortive infection of canine cells by herpes simplex virus. 3. The interference of conditional lethal virus with an extended host range mutant

scientific article published in September 1965

Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1.

scientific article published on October 1999

Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1

scientific article

Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis

scientific article

Activation of herpes simplex virus 1 gamma 2 genes by viral DNA replication

scientific article

Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein.

scientific article published in August 1999

Alpha 4, the major regulatory protein of herpes simplex virus type 1, is stably and specifically associated with promoter-regulatory domains of alpha genes and of selected other viral genes

scientific article published on May 1986

Alternatively spliced mRNAs predicted to yield frame-shift proteins and stable intron 1 RNAs of the herpes simplex virus 1 regulatory gene alpha 0 accumulate in the cytoplasm of infected cells

scientific article published on October 1996

Amplification by host cell factors of a sequence contained within the herpes simplex virus 1 genome

scientific article

An amino acid sequence shared by the herpes simplex virus 1 alpha regulatory proteins 0, 4, 22, and 27 predicts the nucleotidylylation of the UL21, UL31, UL47, and UL49 gene products

scientific article published on July 1994

An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.

scientific article

An inquiry into the mechanisms of herpes simplex virus latency

scientific article published on January 1987

An inquiry into the molecular basis of HSV latency and reactivation

scientific article published on January 2013

An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

scholarly article

Analyses of HSV Proteins for Posttranslational Modifications and Enzyme Functions

scientific article published on January 1, 1998

Analyses of transplanted murine tumors for HSV DNA sequences

scientific article published on 01 September 1986

Anatomy of Herpes Simplex Virus DNA XII. Accumulation of Head-to-Tail Concatemers in Nuclei of Infected Cells and Their Role in the Generation of the Four Isomeric Arrangements of Viral DNA ⬇️

scientific article published on February 1, 1979

Anatomy of Herpes Simplex Virus DNA. IX. Apparent Exclusion of Some Parental DNA Arrangements in the Generation of Intertypic (HSV-1 × HSV-2) Recombinants ⬇️

scientific article published on October 1, 1977

Anatomy of Herpes Simplex Virus DNA. VIII. Properties of the Replicating DNA ⬇️

scientific article published on August 1, 1977

Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants ⬇️

scientific article published on May 1, 1978

Anatomy of herpes simplex virus DNA VII. alpha-RNA is homologous to noncontiguous sites in both the L and S components of viral DNA ⬇️

scientific article published on January 1, 1977

Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitions ⬇️

scientific article published on June 1, 1975

Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them ⬇️

scientific article published on July 1, 1975

Anatomy of herpes simplex virus DNA. V. Terminally repetitive sequences ⬇️

scientific article published on February 1, 1976

Anatomy of herpes simplex virus DNA. VI. Defective DNA originates from the S component ⬇️

scientific article published on November 1, 1976

Anatomy of herpes simplex virus DNA. XI. Apparent clustering of functions effecting rapid inhibition of host DNA and protein synthesis ⬇️

scientific article published on February 1, 1979

Anatomy of herpes simplex virus DNA: evidence for four populations of molecules that differ in the relative orientations of their long and short components ⬇️

scientific article published on November 1, 1975

Anatomy of herpes simplex virus DNA: strain differences and heterogeneity in the locations of restriction endonuclease cleavage sites ⬇️

scientific article published on May 1, 1975

Anatomy of the herpes simplex virus 1 strain F glycoprotein B gene: primary sequence and predicted protein structure of the wild type and of monoclonal antibody-resistant mutants

scientific article

Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA.

scientific article published on 4 June 2007

Application of Denatured, Electrophoretically Separated, and Immobilized Lysates of Herpes Simplex Virus-Infected Cells for Detection of Monoclonal Antibodies and for Studies of the Properties of Viral Proteins ⬇️

scientific article published on April 1, 1983

Application of antibody to synthetic peptides for characterization of the intact and truncated alpha 22 protein specified by herpes simplex virus 1 and the R325 alpha 22- deletion mutant

scientific article published on October 1985

Application of molecular genetics to the design of live herpes simplex virus vaccines

scientific article published on January 1, 1982

Application of the mini-Mu-phage for target-sequence-specific insertional mutagenesis of the herpes simplex virus genome

scientific article published on July 1985

Arrangement of herpesvirus deoxyribonucleic acid in the core

scientific article published on November 1972

Assemblons: nuclear structures defined by aggregation of immature capsids and some tegument proteins of herpes simplex virus 1

scientific article published in July 1996

Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of her

scientific article

Association of herpes simplex virus regulatory protein ICP22 with transcriptional complexes containing EAP, ICP4, RNA polymerase II, and viral DNA requires posttranslational modification by the U(L)13 proteinkinase.

scientific article published in February 1997

Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow

scholarly article

Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in HEp-2 cells

scientific article

Bcl-2 blocks accretion or depletion of stored calcium but has no effect on the redistribution of IP3 receptor I mediated by glycoprotein E of herpes simplex virus 1.

scientific article published on 4 April 2007

Binding of the herpes simplex virus major regulatory protein to viral DNA.

scientific article

Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1-infected cells to its cis site requires cellular proteins

scientific article

Buoyant density of herpes simplex virus in solutions of caesium chloride

scientific article published in May 1967

Casein kinase II specifically nucleotidylylates in vitro the amino acid sequence of the protein encoded by the alpha 22 gene of herpes simplex virus 1.

scientific article

Cation-independent mannose 6-phosphate receptor blocks apoptosis induced by herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein

scientific article

Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1.

scientific article

Cell type dependence of herpes simplex virus gene expression and of processing of viral protein

scientific article

Cell-specific selection of mutants of a herpes simplex virus recombinant carrying deletions

scientific article

Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs

scientific article

Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus

scientific article

Cellular compartmentalization of herpesvirus antigens during viral replication

scientific article published on February 1967

Cellular elongation factor 1delta is modified in cells infected with representative alpha-, beta-, or gammaherpesviruses

scientific article

Cellular proteins specifically bind single- and double-stranded DNA and RNA from the initiation site of a transcript that crosses the origin of DNA replication of herpes simplex virus 1.

scientific article

Characterization and nucleotide sequence of two herpes simplex virus 1 genes whose products modulate alpha-trans-inducing factor-dependent activation of alpha genes

scientific article published on April 1987

Characterization of DNA sequence-common and sequence-specific proteins binding to cis-acting sites for cleavage of the terminal a sequence of the herpes simplex virus 1 genome

scientific article published on March 1989

Characterization of a herpes simplex virus sequence which binds a cellular protein as either a single-stranded or double-stranded DNA or RNA ⬇️

scientific article published on June 1, 1992

Characterization of a recombinant herpes simplex virus 1 designed to enter cells via the IL13Ralpha2 receptor of malignant glioma cells

scientific article

Characterization of a temperature-sensitive mutant of the UL15 open reading frame of herpes simplex virus 1

scientific article published on August 1993

Characterization of a viable, noninverting herpes simplex virus 1 genome derived by insertion and deletion of sequences at the junction of components L and S.

scientific article published on May 1983

Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies ⬇️

scientific article published on October 1, 1984

Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells

scientific article published in May 1968

Characterization of post-translational products of herpes simplex virus gene 35 proteins binding to the surfaces of full capsids but not empty capsids

scientific article published on January 1984

Characterization of the DNA of herpesviruses associated with Lucké adenocarcinoma of the frog and Burkitt lymphoma of man ⬇️

scientific article published on 01 September 1970

Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes.

scientific article published on May 1983

Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0.

scientific article

Characterization of the products of the U(L)43 gene of herpes simplex virus 1: potential implications for regulation of gene expression by antisense transcription

scientific article published in November 1996

Characterization of the protease and other products of amino-terminus-proximal cleavage of the herpes simplex virus 1 UL26 protein.

scientific article published on March 1993

Checkpoints in productive and latent infections with herpes simplex virus 1: conceptualization of the issues ⬇️

scientific article published on November 4, 2011

Chicken Ovalbumin Gene Fused to a Herpes Simplex Virus α Promoter and Linked to a Thymidine Kinase Gene Is Regulated Like a Viral Gene ⬇️

scientific article published on March 1, 1982

Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression ⬇️

scientific article published on September 27, 2010

Cloning of reiterated and nonreiterated herpes simplex virus 1 sequences as BamHI fragments ⬇️

scientific article published on July 1, 1980

Clustering of genes dispensable for growth in culture in the S component of the HSV-1 genome

scientific article published on May 1987

Colocalization of the Herpes Simplex Virus 1 UL4 Protein with Infected Cell Protein 22 in Small, Dense Nuclear Structures Formed prior to Onset of DNA Synthesis.

scientific article published in July 1999

Colocalization of the herpes simplex virus 1 UL4 protein with infected cell protein 22 in small, dense nuclear structures formed prior to onset of DNA synthesis

scientific article

Colonization of murine ganglia by a superinfecting strain of herpes simplex virus ⬇️

scientific article published on August 1, 1983

Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma

scientific article

Compartmentalization of Spermine and Spermidine in the Herpes Simplex Virion ⬇️

scientific article published on November 1, 1971

Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells

scientific article

Concerning the egress of herpes simplex virus from infected cells: electron and light microscope observations

scientific article published on May 1969

Conservation of the architecture of the Golgi apparatus related to a differential organization of microtubules in polykaryocytes induced by syn- mutants of herpes simplex virus 1.

scientific article published in February 1998

Construction and properties of a cell line constitutively expressing the herpes simplex virus glycoprotein B dependent on functional alpha 4 protein synthesis

scientific article

Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13alpha2 receptor

scholarly article

Construction and properties of a recombinant herpes simplex virus 1 lacking both S-component origins of DNA synthesis

scientific article published on April 1993

Construction and properties of a viable herpes simplex virus 1 recombinant lacking coding sequences of the alpha 47 gene

scientific article

Current frontiers in virology

scientific article published on 01 April 1994

DNA Restriction-Enzyme Analysis of Herpes Simplex Virus Isolates Obtained from Patients with Encephalitis ⬇️

scientific article published on October 21, 1982

DNA fingerprinting in investigation of apparent nosocomial acquisition of neonatal herpes simplex ⬇️

scientific article published on 01 July 1980

DNA-binding site of major regulatory protein alpha 4 specifically associated with promoter-regulatory domains of alpha genes of herpes simplex virus type 1

scientific article published on July 1986

Delineation of regulatory domains of early (beta) and late (gamma 2) genes by construction of chimeric genes expressed in herpes simplex virus 1 genomes.

scientific article

Demonstration of Exogenous Genital Reinfection with Herpes Simplex Virus Type 2 by Restriction Endonuclease Fingerprinting of Viral DNA ⬇️

scientific article published on September 1, 1979

Development of a high-throughput quantitative assay for detecting herpes simplex virus DNA in clinical samples

scientific article

Differences in the poly(ADP-ribosyl)ation patterns of ICP4, the herpes simplex virus major regulatory protein, in infected cells and in isolated nuclei ⬇️

scientific article published on November 1, 1992

Differential immunologic reactivity and processing of glycoproteins gA and gB of herpes simplex virus types 1 and 2 made in Vero and HEp-2 cells ⬇️

scientific article published on August 1, 1981

Differential response of human cells to deletions and stop codons in the gamma(1)34.5 gene of herpes simplex virus.

scientific article published on December 1994

Differentiation and DNA contact points of host proteins binding at the cis site for virion-mediated induction of alpha genes of herpes simplex virus 1.

scientific article published on April 1988

Differentiation between alpha promoter and regulator regions of herpes simplex virus 1: the functional domains and sequence of a movable alpha regulator ⬇️

scientific article published on August 1, 1982

Differentiation of Respiratory and Abortigenic Isolates of Equine Herpesvirus 1 by Restriction Endonucleases ⬇️

scientific article published on October 30, 1981

Differentiation of multiple domains in the herpes simplex virus 1 protease encoded by the UL26 gene ⬇️

scientific article published on March 15, 1992

Differentiation of nuclear and cytoplasmic herpesvirus antigens in infected cells

scientific article published in August 1966

Differentiation of the shutoff of protein synthesis by virion host shutoff and mutant gamma (1)34.5 genes of herpes simplex virus 1.

scientific article published on March 1997

Disruption of HDAC/CoREST/REST repressor by dnREST reduces genome silencing and increases virulence of herpes simplex virus ⬇️

scientific article published on August 23, 2010

Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts

scientific article

During its nuclear phase the multifunctional regulatory protein ICP0 undergoes proteolytic cleavage characteristic of polyproteins

scientific article published on 22 October 2009

E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.

scientific article

Effect of the Vinca Alkaloids on RNA Synthesis in Human Cells in vitro ⬇️

scientific article published on 01 November 1968

Engagement of the lysine-specific demethylase/HDAC1/CoREST/REST complex by herpes simplex virus 1.

scientific article published on 04 February 2009

Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interaction

scientific article

Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors ⬇️

scientific article published on February 1, 1998

Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virus

scientific article published on January 1988

Epstein-Barr virus genome may encode a protein showing significant amino acid and predicted secondary structure homology with glycoprotein B of herpes simplex virus 1.

scientific article published on December 1985

Establishment of latency in mice by herpes simplex virus 1 recombinants that carry insertions affecting regulation of the thymidine kinase gene

scientific article published on August 1985

Eukaryotic Elongation Factor 1δ Is Hyperphosphorylated by the Protein Kinase Encoded by the U L 13 Gene of Herpes Simplex Virus 1 ⬇️

scientific article published on March 1, 1998

Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors.

scientific article

Expression and regulation of glycoprotein C gene of herpes simplex virus 1 resident in a clonal L-cell line.

scientific article published on May 1986

Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript.

scientific article published on September 1994

Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinase

scientific article published on 5 March 2008

Expression of hepatitis B virus S gene by herpes simplex virus type 1 vectors carrying alpha- and beta-regulated gene chimeras

scientific article published on September 1984

Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis

scientific article published in May 2001

Expression of the herpes simplex virus 1 alpha transinducing factor (VP16) does not induce reactivation of latent virus or prevent the establishment of latency in mice ⬇️

scientific article published on June 1, 1991

Extracellular pH and herpes simplex virus multiplication.

scientific article published in August 1965

Failure to induce cervical cancer in mice by long-term frequent vaginal exposure to live or inactivated herpes simplex viruses

scientific article published on 01 September 1986

Fragmentation and dispersal of Golgi proteins and redistribution of glycoproteins and glycolipids processed through the Golgi apparatus after infection with herpes simplex virus 1

scientific article

Friendly fire: redirecting herpes simplex virus-1 for therapeutic applications

scientific article

Functional anatomy of herpes simplex virus 1 overlapping genes encoding infected-cell protein 22 and US1.5 protein

scientific article

Functional interaction and colocalization of the herpes simplex virus 1 major regulatory protein ICP4 with EAP, a nucleolar-ribosomal protein

scientific article published on May 1996

Generation of an inverting herpes simplex virus 1 mutant lacking the L-S junction a sequences, an origin of DNA synthesis, and several genes including those specifying glycoprotein E and the alpha 47 gene

scientific article published on May 1986

Genetic engineering and properties of novel herpes simplex viruses for use as potential vaccines and as vectors of foreign genes.

scientific article

Genetic engineering of novel genomes of large DNA viruses

scientific article

Genetic engineering of viruses and of virus vectors: a preface

scientific article published on October 1996

Genetic relatedness of type 1 and type 2 herpes simplex viruses.

scientific article published on May 1972

Genetic variation of viruses. Introductory remarks

scientific article published on 01 January 1980

Genetically engineered HSV in the treatment of glioma: a review

scientific article

Genome variation and evolution among herpes viruses

scientific article published on January 1980

Glycoprotein C-dependent attachment of herpes simplex virus to susceptible cells leading to productive infection

scientific article published on September 1990

Glycoprotein D of herpes simplex virus encodes a domain which precludes penetration of cells expressing the glycoprotein by superinfecting herpes simplex virus

scientific article published on December 1990

Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins

scientific article

Glycoprotein M of herpes simplex virus 1 is incorporated into virions during budding at the inner nuclear membrane

scientific article published on November 2006

Guanylylation and adenylylation of the alpha regulatory proteins of herpes simplex virus require a viral beta or gamma function

scientific article published on July 1993

HSV carrying WT REST establishes latency but reactivates only if the synthesis of REST is suppressed

scientific article published on 22 January 2013

HSV gene functions: what have we learned that could be generally applicable to its near and distant cousins?

scientific article

HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation

scientific article published on 21 January 2014

HSV-1 gene expression from reactivated ganglia is disordered and concurrent with suppression of latency-associated transcript and miRNAs ⬇️

scientific article published on November 7, 2011

Herpes Simplex Virus 1 Gene Expression Is Accelerated by Inhibitors of Histone Deacetylases in Rabbit Skin Cells Infected with a Mutant Carrying a cDNA Copy of the Infected-Cell Protein No. 0 ⬇️

scientific article published on December 1, 2003

Herpes Simplex Virus 1 Regulatory Protein ICP22 Interacts with a New Cell Cycle-Regulated Factor and Accumulates in a Cell Cycle-Dependent Fashion in Infected Cells ⬇️

scientific article published on November 1, 1998

Herpes Simplex Virus Glycoprotein gA/B: Evidence that the Infected Vero Cell Products Comap and Arise by Proteolysis ⬇️

scientific article published on October 1, 1982

Herpes Simplex Viruses ⬇️

scientific article published on March 1, 1998

Herpes simplex genes: the blueprint of a successful human pathogen

scientific article published on 01 August 1994

Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions

scientific article

Herpes simplex virus 1 RNA-binding protein US11 negatively regulates the accumulation of a truncated viral mRNA ⬇️

scientific article published on November 1, 1991

Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes

scholarly article

Herpes simplex virus 1 alpha regulatory protein ICP0 functionally interacts with cellular transcription factor BMAL1.

scholarly article

Herpes simplex virus 1 alpha regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3 ⬇️

scientific article published on October 1, 1997

Herpes simplex virus 1 blocks caspase-3-independent and caspase-dependent pathways to cell death

scientific article

Herpes simplex virus 1 gamma(1)34.5 gene function, which blocks the host response to infection, maps in the homologous domain of the genes expressed during growth arrest and DNA damage

scientific article

Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites

scientific article published on April 2004

Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner ⬇️

scientific article published on March 31, 1998

Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs

scientific article

Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces

scientific article

Herpes simplex virus 1 mutant deleted in the alpha 22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice

scientific article

Herpes simplex virus 1 mutant in which the ICP0 HUL-1 E3 ubiquitin ligase site is disrupted stabilizes cdc34 but degrades D-type cyclins and exhibits diminished neurotoxicity

scientific article

Herpes simplex virus 1 open reading frames O and P are not necessary for establishment of latent infection in mice

scientific article

Herpes simplex virus 1 precludes replenishment of the short-lived receptor of tumor necrosis factor alpha by virion host shutoff-dependent degradation of its mRNA.

scientific article

Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture

scientific article

Herpes simplex virus 1 recombinant virions exhibiting the amino terminal fragment of urokinase-type plasminogen activator can enter cells via the cognate receptor

scientific article published on April 2006

Herpes simplex virus 1 recombinants with noninverting genomes frozen in different isomeric arrangements are capable of independent replication

scientific article published on August 1986

Herpes simplex virus 1 reiterated S component sequences (c1) situated between the a sequence and alpha 4 gene are not essential for virus replication

scientific article published on May 1985

Herpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymes

scientific article

Herpes simplex virus DNA in transformed cells: sequence complexity in five hamster cell lines and one derived hamster tumor ⬇️

scientific article published on June 1, 1976

Herpes simplex virus expressing Epstein-Barr virus nuclear antigen 1.

scientific article

Herpes simplex virus glycoprotein D is sufficient to induce spontaneous pH-independent fusion in a cell line that constitutively expresses the glycoprotein

scientific article

Herpes simplex virus infections

scientific article

Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA.

scientific article

Herpes simplex virus phosphoproteins. II. Characterization of the virion protein kinase and of the polypeptides phosphorylated in the virion ⬇️

scientific article published on September 1, 1980

Herpes simplex virus products in productive and abortive infection. 3. Differentiation of infectious virus derived from nucleus and cytoplasm with respect to stability and size

scientific article published on October 1968

Herpes simplex virus products in productive and abortive infection. I. Stabilization with formaldehyde and preliminary analyses by isopycnic centrifugation in CsCl.

scientific article published on April 1967

Herpes simplex virus products in productive and abortive infection. II. Electron microscopic and immunological evidence for failure of virus envelopment as a cause of abortive infection.

scientific article published on April 1968

Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis

scholarly article

Herpes simplex virus vaccines

scientific article published on 01 January 1985

Herpes simplex virus virulence: the functions of the gamma (1)34.5 gene

scientific article published in May 1997

Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex

scientific article

Herpes simplex viruses: is a vaccine tenable?

scientific article

Herpes vimplex virus: genome size and redundancy studied by renaturation kinetics

scientific article published on October 1971

Herpesviridae. Definition, provisional nomenclature, and taxonomy. The Herpesvirus Study Group, the International Committee on Taxonomy of Viruses

scientific article published in January 1981

Herpesvirus antigens on cell membranes detected by centrifugation of membrane-antibody complexes

scientific article published in January 1971

Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication ⬇️

scientific article published on September 1, 1982

Herpesviruses, latency and cancer: a biochemical approach

scientific article

Host cell proteins bind to the cis-acting site required for virion-mediated induction of herpes simplex virus 1 alpha genes

scientific article

Human herpersviruses I: a model for molecular organization and regulation of herpesviruses-a review

scientific article published on 01 January 1975

Human herpesvirus 1 as a model of regulation of herpesvirus macromolecular metabolism: a review

scientific article published on 01 January 1978

ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression

scholarly article

ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells

scientific article published on 12 August 2009

ICP4, the major regulatory protein of herpes simplex virus, shares features common to GTP-binding proteins and is adenylated and guanylated ⬇️

scientific article published on July 1, 1991

Identification and genetic mapping of a herpes simplex virus capsid protein that binds DNA ⬇️

scientific article published on May 1, 1984

Identification and preliminary mapping with monoclonal antibodies of a herpes simplex virus 2 glycoprotein lacking a known type 1 counterpart ⬇️

scientific article published on February 1, 1984

Identification by antibody to a synthetic peptide of a protein specified by a diploid gene located in the terminal repeats of the L component of herpes simplex virus genome

scientific article published on June 1986

Identification of a herpes simplex virus 1 glycoprotein gene within a gene cluster dispensable for growth in cell culture

scientific article

Identification of a new transcriptional unit that yields a gene product within the unique sequences of the short component of the herpes simplex virus 1 genome.

scientific article published on July 1993

Identification of a novel expressed open reading frame situated between genes U(L)20 and U(L)21 of the herpes simplex virus 1 genome

scientific article

Identification of the herpes simplex virus-1 protease cleavage sites by direct sequence analysis of autoproteolytic cleavage products

scientific article published in January 1993

Identification of three genes nonessential for growth in cell culture near the right terminus of the unique sequences of long component of herpes simplex virus 1.

scientific article

Identification, properties, and gene location of a novel glycoprotein specified by herpes simplex virus 1.

scientific article published on April 1986

Immunization against viral infections associated with human cancer: the promise of modern biotechnology

scientific article published on 01 March 1988

Immunization of experimental animals with reconstituted glycoprotein mixtures of herpes simplex virus 1 and 2: protection against challenge with virulent virus

scientific article

Immunological reactivity of herpes simplex virus 1 and 2 polypeptides electrophoretically separated and transferred to diazobenzyloxymethyl paper.

scientific article

Immunological specificity of the glycoproteins of herpes simplex virus subtypes 1 and 2.

scientific article published in October 1972

In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.

scientific article

In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus)

scientific article published on 01 August 1990

In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020: construction and evaluation in rodents

scientific article published in September 1988

Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model

scientific article published on July 2005

Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1 ⬇️

scientific article published on May 5, 2011

Induction of apoptosis accelerates reactivation of latent HSV-1 in ganglionic organ cultures and replication in cell cultures ⬇️

scientific article published on August 20, 2012

Induction of reactivation of herpes simplex virus in murine sensory ganglia in vivo by cadmium.

scientific article published on December 1993

Infected Cell Protein 22 of Herpes Simplex Virus 1 Regulates the Expression of Virion Host Shutoff Gene UL41 ⬇️

scientific article published on August 4, 1997

Infected cell protein No. 22 is subject to proteolytic cleavage by caspases activated by a mutant that induces apoptosis

scientific article published on January 2003

Infection of polarized MDCK cells with herpes simplex virus 1: two asymmetrically distributed cell receptors interact with different viral proteins ⬇️

scientific article published on June 15, 1991

Infection with herpes-simplex viruses 1 and 2. 1.

scientific article

Infection with herpes-simplex viruses 1 and 2. 3.

scientific article

Infection with herpes-simplex viruses 1 and 2. II.

scientific article

Infectious agents and cancer: criteria for a causal relation

scientific article

Innate responses to gene knockouts impact overlapping gene networks and vary with respect to resistance to viral infection

article published in the Proceedings of the National Academy of Sciences of the United States of America

Interaction of herpes simplex virus 1 alpha regulatory protein ICP0 with elongation factor 1delta: ICP0 affects translational machinery

scientific article published in February 1997

Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention

scientific article published on 17 July 2013

Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNA

scholarly article

Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes

scientific article

Introduction: objectives of herpes simplex virus vaccines seen from a historical perspective

scientific article

Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.

scientific article published in October 2005

Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus.

scientific article published in June 1999

Isomerization of herpes simplex virus 1 genome: identification of the cis-acting and recombination sites within the domain of the a sequence

scientific article published on July 1985

Localization and putative function of the UL20 membrane protein in cells infected with herpes simplex virus 1.

scientific article published on November 1994

Localization of Frog Virus Multiplication in Chick Embryo Cells by Immunofluorescence

scientific article published in February 1967

Macromolecular biosynthesis in animal cells infected with cytolytic viruses

scientific article

Macromolecular synthesis in cells infected with herpes simplex virus

scientific article published in June 1965

Mapping of functional and antigenic domains of the alpha 4 protein of herpes simplex virus 1.

scientific article published on February 1988

Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection

scientific article

Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

scientific article published in November 1990

Mapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptides

scientific article

Mapping of the Thymidine Kinase Genes of Type 1 and Type 2 Herpes Simplex Viruses using Intertypic Recombinants ⬇️

scientific article published on August 1, 1980

Marek's disease herpes virus: a cytomegalovirus

scientific article

Modulation of reactivation of latent herpes simplex virus 1 in ganglionic organ cultures by p300/CBP and STAT3.

scientific article published on 20 June 2013

Modulation of vascular remodeling induced by a brief intraluminal exposure to the recombinant R7020 strain of Herpes simplex-1.

scientific article

Molecular Genetics of Herpes Simplex Virus II. Mapping of the Major Viral Glycoproteins and of the Genetic Loci Specifying the Social Behavior of Infected Cells ⬇️

scientific article published on February 1, 1979

Molecular Pathways: Interferon/Stat1 Pathway: Role in the Tumor Resistance to Genotoxic Stress and Aggressive Growth ⬇️

scientific article published on May 21, 2012

Molecular biology of herpes simplex virus

scientific article published on January 1, 1992

Molecular engineering of the herpes simplex virus genome: Insertion of a second L-S junction into the genome causes additional genome inversions ⬇️

scientific article published on November 1, 1980

Molecular genetics of herpes simplex virus. III. Fine mapping of a genetic locus determining resistance to phosphonoacetate by two methods of marker transfer ⬇️

scientific article published on February 1, 1979

Molecular genetics of herpes simplex virus. V. Characterization of a mutant defective in ability to form plaques at low temperatures and in a viral fraction which prevents accumulation of coreless capsids at nuclear pores late in infection

scientific article published on December 1981

Molecular genetics of herpes simplex virus. VI. Characterization of a temperature-sensitive mutant defective in the expression of all early viral gene products

scientific article

Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides ⬇️

scientific article published on January 1, 1981

Molecular genetics of herpes simplex virus. VIII. further characterization of a temperature-sensitive mutant defective in release of viral DNA and in other stages of the viral reproductive cycle ⬇️

scientific article published on January 1, 1983

Molecular genetics of herpes simplex virus: Demonstration of regions of obligatory and nonobligatory identity within diploid regions of the genome by sequence replacement and insertion ⬇️

scientific article published on August 1, 1978

Molecular genetics of herpes simplex virus: The terminal a sequences of the L and S components are obligatorily identical and constitute a part of a structural gene mapping predominantly in the S component ⬇️

scientific article published on September 1, 1979

Molecular organization and expression of herpes simplex DNA

scientific article published on January 1, 1976

Molecular targeting of gene therapy and radiotherapy

scientific article

Mutational analysis of the ICP4 binding sites in the 5' transcribed noncoding domains of the herpes simplex virus 1 UL 49.5 gamma 2 gene ⬇️

scientific article published on August 1, 1992

Mutational analysis of the promoter region of the alpha 27 gene of herpes simplex virus 1 within the context of the viral genome

scientific article

Mutations affecting conformation or sequence of neutralizing epitopes identified by reactivity of viable plaques segregate from syn and ts domains of HSV-1(F) gB gene

scientific article

New viral footprints in Kaposi's sarcoma

scientific article published on 01 May 1995

Nomenclature and classification of herpesviruses: a proposal ⬇️

scientific article published on January 1, 1972

Nosocomial herpetic infections in a pediatric intensive care unit ⬇️

scientific article published on February 1, 1981

Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1

scholarly article

Nucleotide sequence and predicted amino acid sequence of a protein encoded in a small herpes simplex virus DNA fragment capable of trans-inducing alpha genes

scientific article published on September 1985

Oct-1 Is Posttranslationally Modified and Exhibits Reduced Capacity To Bind Cognate Sites at Late Times after Infection with Herpes Simplex Virus 1 ⬇️

scientific article published on November 1, 2003

Ocular disease pattern induced by herpes simplex virus is genetically determined by a specific region of viral DNA ⬇️

scientific article published on February 1, 1982

Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection

scientific article

On the Structure, Functional Equivalence, and Replication of the Four Arrangements of Herpes Simplex Virus DNA ⬇️

scientific article published on January 1, 1979

Open reading frame P--a herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA

scientific article published on September 1996

Origin of unenveloped capsids in the cytoplasm of cells infected with herpes simplex virus 1

scientific article published on March 1991

Overexpression of promyelocytic leukemia protein precludes the dispersal of ND10 structures and has no effect on accumulation of infectious herpes simplex virus 1 or its proteins

scientific article

Overexpression of the Ubiquitin-Specific Protease 7 Resulting from Transfection or Mutations in the ICP0 Binding Site Accelerates Rather than Depresses Herpes Simplex Virus 1 Gene Expression ⬇️

scientific article published on September 19, 2012

PML plays both inimical and beneficial roles in HSV-1 replication

scientific article published on 09 May 2016

PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2.

scientific article

Partial substitution of the functions of the herpes simplex virus 1 U(L)13 gene by the human cytomegalovirus U(L)97 gene

scientific article published in November 1996

Patterns of accumulation of miRNAs encoded by herpes simplex virus during productive infection, latency, and on reactivation

scientific article

Phenotypic properties of herpes simplex virus 1 containing a derepressed open reading frame P gene.

scientific article published in March 1996

Polysomes and protein synthesis in cells infected with a DNA virus

scientific article published in July 1966

Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells

scientific article published in November 2004

Posttranscriptional regulation of US11 in cells infected with a herpes simplex virus 1 recombinant lacking both 222-bp domains containing S-component origins of DNA synthesis

scientific article published on July 1999

Posttranslational processing of infected cell protein 22 mediated by viral protein kinases is sensitive to amino acid substitutions at distant sites and can be cell-type specific

scientific article

Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize

scientific article

Preparation of herpes simplex virus of high titer.

scientific article published on January 1968

Prevention of restenosis by a herpes simplex virus mutant capable of controlled long-term expression in vascular tissue in vivo

scientific article published in December 2001

Processing of the herpes simplex virus regulatory protein alpha 22 mediated by the UL13 protein kinase determines the accumulation of a subset of alpha and gamma mRNAs and proteins in infected cells

scientific article

Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effects

scientific article

Properties of the protein encoded by the UL32 open reading frame of herpes simplex virus 1

scientific article published in June 1996

Properties of two 5'-coterminal RNAs transcribed part way and across the S component origin of DNA synthesis of the herpes simplex virus 1 genome

scientific article

Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1

scientific article

Proteins specified by herpes simplex virus, IV. Site of glycosylation and accumulation of viral membrane proteins

scientific article

Proteins specified by herpes simplex virus. 3. Viruses differing in their effects on the social behavior of infected cells specify different membrane glycoproteins

scientific article

Proteins specified by herpes simplex virus. 8. Characterization and composition of multiple capsid forms of subtypes 1 and 2.

scientific article published on November 1972

Proteins specified by herpes simplex virus. IX. Contiguity of host and viral proteins in the plasma membrane of infected cells

scientific article published on May 1973

Proteins specified by herpes simplex virus. Staining and radiolabeling properties of B capsid and virion proteins in polyacrylamide gels

scientific article published on January 1974

Proteins specified by herpes simplex virus. V. Purification and structural proteins of the herpesvirion

scientific article published on January 1972

Proteins specified by herpes simplex virus. VI. Viral proteins in the plasma membrane

scientific article published on March 1972

Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell.

scientific article published on December 1973

Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains

scientific article published on September 1974

Proteins specified by herpes simplex virus. XIII. Glycosylation of viral polypeptides ⬇️

scientific article published on November 1, 1975

Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus

scientific article

Pseudotype formation between enveloped RNA and DNA viruses

scientific article published on 01 December 1974

RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.

scientific article published on 13 January 2014

RNA synthesis in cells infected with herpes simple virus. XIII. Differences in the methylation patterns of viral RNA during the reproductive cycle ⬇️

scientific article published on December 1, 1976

RNA synthesis in cells infected with herpes simplex virus. 3. Absence of virus-specified arginyl- and seryl-tRNA in infected HEp-2 cells

scientific article published in September 1970

RNA synthesis in cells infected with herpes simplex virus. II. Evidence that a class of viral mRNA is derived from a high molecular weight precursor synthesized in the nucleus

scientific article

RNA synthesis in cells infected with herpes simplex virus. IX. Evidence for accumulation of abundant symmetric transcripts in nuclei ⬇️

scientific article published on January 1, 1975

RNA synthesis in cells infected with herpes simplex virus. VII. Control of transcription and of transcript abundancies of unique and common sequences of herpes simplex virus 1 and 2

scientific article published on June 1973

RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them ⬇️

scientific article published on April 1, 1975

RNA synthesis in cells infected with herpes simplex virus. XII. Sequence complexity and properties of RNA differing in extent of adenylation ⬇️

scientific article published on June 1, 1976

RNA synthesis in cells infected with herpes simplex virus: analysis of high molecular weight and symmetrical viral transcripts in herpesvirus infected cells

scientific article published on 01 January 1975

RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions.

scientific article

Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling

scientific article

ReVOLT: radiation-enhanced viral oncolytic therapy

scientific article published on November 2006

Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation

scientific article

Redefining virology

scientific article published on 01 June 2000

Redistribution of microtubules and Golgi apparatus in herpes simplex virus-infected cells and their role in viral exocytosis.

scientific article published in December 1995

Regulation of Herpesvirus Macromolecular Synthesis: Evidence for Multilevel Regulation of Herpes Simplex 1 RNA and Protein Synthesis ⬇️

scientific article published on January 1, 1975

Regulation of glycoprotein D synthesis: does alpha 4, the major regulatory protein of herpes simplex virus 1, regulate late genes both positively and negatively?

scientific article published on January 1988

Regulation of herpes simplex virus 1 genes: alpha gene sequence requirements for transient induction of indicator genes regulated by beta or late (gamma 2) promoters

scientific article

Regulation of herpesvirus macromolecular synthesis V. Properties of α polypeptides made in HSV-1 and HSV-2 infected cells ⬇️

scientific article published on April 1, 1977

Regulation of herpesvirus macromolecular synthesis VII. Inhibition of internal methylation of mRNA late in infection ⬇️

scientific article published on March 1, 1978

Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins

scientific article

Regulation of herpesvirus macromolecular synthesis. VI. Synthesis and modification of viral polypeptides in enucleated cells ⬇️

scientific article published on June 1, 1977

Regulation of herpesvirus macromolecular synthesis. VIII. The transcription program consists of three phases during which both extent of transcription and accumulation of RNA in the cytoplasm are regulated ⬇️

scientific article published on August 1, 1979

Regulation of herpesvirus macromolecular synthesis: nuclear retention of nontranslated viral RNA sequences

scientific article

Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides ⬇️

scientific article published on April 1, 1975

Regulation of herpesvirus macromolecular synthesis: temporal order of transcription of alpha genes is not dependent on the stringency of inhibition of protein synthesis ⬇️

scientific article published on October 1, 1981

Regulation of herpesvirus macromolecular synthesis: transcription-initiation sites and domains of alpha genes ⬇️

scientific article published on December 1, 1980

Regulation of α Genes of Herpes Simplex Virus: The α 27 Gene Promoter-Thymidine Kinase Chimera Is Positively Regulated in Converted L Cells ⬇️

scientific article published on September 1, 1982

Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters ⬇️

scientific article published on May 1, 1981

Relationship between post-transcriptional adenylation of herpes virus RNA and messenger RNA abundance

scientific article

Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models

scientific article published on June 1993

Replication-competent herpes simplex viral vectors for cancer therapy

scientific article

Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.

scientific article

Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors

scientific article published in May 1999

Repression of the herpes simplex virus 1 alpha 4 gene by its gene product (ICP4) within the context of the viral genome is conditioned by the distance and stereoaxial alignment of the ICP4 DNA binding site relative to the TATA box

scientific article published in May 1995

Repression of the herpes simplex virus 1 alpha 4 gene by its gene product occurs within the context of the viral genome and is associated with all three identified cognate sites

scientific article

Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus 1

scientific article

Restriction Endonuclease Fingerprinting of Herpes Simplex Virus DNA: A Novel Epidemiological Tool Applied to a Nosocomial Outbreak ⬇️

scientific article published on October 1, 1978

Restriction endonuclease patterns of herpes simplex virus DNA: application to diagnosis and molecular epidemiology.

scientific article published on January 1983

Restriction enzyme analysis of herpesvirus DNA: stability of restriction endonuclease patterns

scientific article published on March 20, 1982

Ribonucleic Acid Synthesis in Cells Infected with Herpes Simplex Virus: Characterization of Viral High Molecular Weight Nuclear RNA

scientific article published on November 1, 1975

Ribonucleic acid synthesis in cells infected with herpes simplex virus. I. Patterns of ribonucleic acid synthesis in productively infected cells.

scientific article published on July 1969

Ribonucleic acid synthesis in cells infected with herpes simplex virus. VI. Polyadenylic acid sequences in viral messenger ribonucleic acid.

scientific article published on October 1972

Ribonucleic acid synthesis in cells infected with herpes simplex virus: controls of transcription and of RNA abundance

scientific article

Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1

scientific article published on March 2004

Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia

scientific article

Role of alpha-transinducing factor (VP16) in the induction of alpha genes within the context of viral genomes ⬇️

scientific article published on July 1, 1991

Role of cdk9 in the optimization of expression of the genes regulated by ICP22 of herpes simplex virus 1

scientific article published on 27 August 2008

Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication

scientific article published on 13 February 2008

Role of cyclin D3 in the biology of herpes simplex virus 1 ICPO.

scientific article

Role of herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal

scientific article

Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase

scientific article

STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells ⬇️

scholarly article

Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence

scientific article

Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein

scientific article published on 15 April 2013

Selective failure of protein synthesis in herpesvirus-infected cells deprived of arginine

scientific article published on 01 August 1969

Separation of receptor-binding and profusogenic domains of glycoprotein D of herpes simplex virus 1 into distinct interacting proteins

scholarly article

Separation of sequences defining basal expression from those conferring alpha gene recognition within the regulatory domains of herpes simplex virus 1 alpha genes ⬇️

scientific article published on July 1, 1984

Separation of the herpesvirus deoxyribonucleic acid duplex into unique fragments and intact strand on sedimentation in alkaline gradients.

scientific article published on October 1972

Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.

scientific article

Similarities and Differences in the Development of Laboratory Strains and Freshly Isolated Strains of Herpes Simplex Virus in HEp-2 Cells: Electron Microscopy.

scientific article

Site-specific inversion sequence of the herpes simplex virus genome: Domain and structural features ⬇️

scientific article published on November 1, 1981

Site-specific mutagenesis of large DNA viral genomes

scientific article

Size and composition of Marek's disease virus deoxyribonucleic acid

scientific article published on March 1971

Size, composition, and structure of the deoxyribonucleic acid of herpes simplex virus subtypes 1 and 2.

scientific article published on August 1971

Small dense nuclear bodies are the site of localization of herpes simplex virus 1 U(L)3 and U(L)4 proteins and of ICP22 only when the latter protein is present

scientific article

Some biophysical properties of frog viruses and their DNA ⬇️

scientific article

State and role of SRC family kinases in replication of herpes simplex virus 1.

scientific article

Structural features of the herpes simplex virus alpha gene 4, 0, and 27 promoter-regulatory sequences which confer alpha regulation on chimeric thymidine kinase genes

scientific article published on December 1982

Structure and function in the herpes simplex virus 1 RNA-binding protein U(s)11: mapping of the domain required for ribosomal and nucleolar association and RNA binding in vitro

scientific article published in May 1996

Structure and role of the herpes simplex virus DNA termini in inversion, circularization and generation of virion DNA ⬇️

scientific article published on November 1, 1982

Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene ⬇️

scientific article published on August 1, 1997

Sustained inhibition of experimental neointimal hyperplasia with a genetically modified herpes simplex virus

scientific article published in June 2003

Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity

scientific article

Temperature-sensitive mutations in the putative herpes simplex virus type 1 terminase subunits pUL15 and pUL33 preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive temperature

scientific article

Temporal Cluster of Herpes Simplex Encephalitis: Investigation by Restriction Endonuclease Cleavage of Viral DNA ⬇️

scientific article published on 01 April 1980

The 3 facets of regulation of herpes simplex virus gene expression: A critical inquiry

scientific article published on 11 March 2015

The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling

scientific article

The Checkpoints of Viral Gene Expression in Productive and Latent Infection: the Role of the HDAC/CoREST/LSD1/REST Repressor Complex ⬇️

scientific article published on March 30, 2011

The CoREST/REST Repressor Is both Necessary and Inimical for Expression of Herpes Simplex Virus Genes ⬇️

scientific article published on December 28, 2010

The DNA-binding properties of the major regulatory protein alpha 4 of herpes simplex viruses

scientific article

The Herpes Simplex Virus 1 U S 3 Protein Kinase Blocks Caspase-Dependent Double Cleavage and Activation of the Proapoptotic Protein BAD ⬇️

scientific article published on June 1, 2003

The Herpes Simplex Virus US11 Protein Effectively Compensates for the γ134.5 Gene if Present before Activation of Protein Kinase R by Precluding Its Phosphorylation and That of the α Subunit of Eukaryotic Translation Initiation Factor 2 ⬇️

scientific article published on November 1, 1998

The Histone Acetyltransferase CLOCK Is an Essential Component of the Herpes Simplex Virus 1 Transcriptome That Includes TFIID, ICP4, ICP27, and ICP22 ⬇️

scientific article published on July 6, 2011

The Maturation of a Scientist: An Autobiography

scientific article published on November 2015

The Molecular Epidemiology of Herpes Simplex Viruses ⬇️

scientific article published on January 1, 1979

The Nucleotidylylation of Herpes Simplex Virus 1 Regulatory Protein α22 by Human Casein Kinase II ⬇️

scientific article published on October 3, 1997

The SP100 component of ND10 enhances accumulation of PML and suppresses replication and the assembly of HSV replication compartments

scientific article published on 24 April 2017

The Second-Site Mutation in the Herpes Simplex Virus Recombinants Lacking the γ 1 34.5 Genes Precludes Shutoff of Protein Synthesis by Blocking the Phosphorylation of eIF-2α ⬇️

scientific article published on September 1, 1998

The Stress-Inducible Immediate-Early Responsive Gene IEX-1 Is Activated in Cells Infected with Herpes Simplex Virus 1, but Several Viral Mechanisms, Including 3′ Degradation of Its RNA, Preclude Expression of the Gene ⬇️

scientific article published on June 1, 2003

The U(L)3 protein of herpes simplex virus 1 is translated predominantly from the second in-frame methionine codon and is subject to at least two posttranslational modifications

scientific article

The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins

scholarly article

The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage

scientific article

The UL 16 gene product of herpes simplex virus 1 is a virion protein that colocalizes with intranuclear capsid proteins

scientific article published on December 1996

The UL10 gene of herpes simplex virus 1 encodes a novel viral glycoprotein, gM, which is present in the virion and in the plasma membrane of infected cells ⬇️

scientific article published on March 1, 1993

The UL11 gene of herpes simplex virus 1 encodes a function that facilitates nucleocapsid envelopment and egress from cells ⬇️

scientific article published on August 1, 1992

The UL13 Protein Kinase and the Infected Cell Type Are Determinants of Posttranslational Modification of ICP0 ⬇️

scientific article published on 01 September 1997

The UL13 gene of herpes simplex virus 1 encodes the functions for posttranslational processing associated with phosphorylation of the regulatory protein alpha 22 ⬇️

scientific article published on August 15, 1992

The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egress

scientific article published on December 1991

The UL21 gene products of herpes simplex virus 1 are dispensable for growth in cultured cells.

scientific article published on May 1994

The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs

scientific article

The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins

scientific article

The alpha promoter regulator-ovalbumin chimeric gene resident in human cells is regulated like the authentic alpha 4 gene after infection with herpes simplex virus 1 mutants in alpha 4 gene

scientific article published in May 1983

The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors

scientific article published on October 1996

The cDNA of UL15, a highly conserved herpes simplex virus 1 gene, effectively replaces the two exons of the wild-type virus ⬇️

scientific article published on September 1, 1992

The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells.

scientific article published in January 1996

The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1.

scientific article

The degradation of promyelocytic leukemia and Sp100 proteins by herpes simplex virus 1 is mediated by the ubiquitin-conjugating enzyme UbcH5a

scientific article

The destruction of smallpox virus stocks in national repositories: a grave mistake and a bad precedent.

scientific article

The disaggregation of host polyribosomes in productive and abortive infection with herpes simplex virus

scientific article published in August 1967

The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes

scientific article

The diversity and unity of Herpesviridae

scientific article published on January 1991

The domains of glycoprotein D required to block apoptosis depend on whether glycoprotein D is present in the virions carrying herpes simplex virus 1 genome lacking the gene encoding the glycoprotein

scientific article

The domains of glycoprotein D required to block apoptosis induced by herpes simplex virus 1 are largely distinct from those involved in cell-cell fusion and binding to nectin1

scientific article

The egress of herpesviruses from cells: the unanswered questions

scientific article published on July 2006

The essential protein encoded by the UL31 gene of herpes simplex virus 1 depends for its stability on the presence of UL34 protein

scientific article published on September 2000

The first 30 minutes in the life of a virus: unREST in the nucleus

scientific article

The function of herpes simplex virus genes: a primer for genetic engineering of novel vectors

scientific article published on October 1996

The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells ⬇️

scientific article published on April 15, 1992

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

scientific article

The glycoprotein C gene of herpes simplex virus 1 resident in clonal L cell lines manifests two regulatory domains conferring a dominant B and a subordinate gamma 2 regulation

scientific article

The herpes simplex virus 1 RNA binding protein US11 is a virion component and associates with ribosomal 60S subunits ⬇️

scientific article published on June 1, 1992

The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane

scientific article

The herpes simplex virus 1 UL11 proteins are associated with cytoplasmic and nuclear membranes and with nuclear bodies of infected cells

scientific article published in February 1995

The herpes simplex virus 1 UL15 gene encodes two proteins and is required for cleavage of genomic viral DNA

scientific article published on December 1994

The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific

scholarly article

The herpes simplex virus 1 gene encoding a protease also contains within its coding domain the gene encoding the more abundant substrate ⬇️

scientific article published on October 1, 1991

The herpes simplex virus 1 gene for ICP34.5, which maps in inverted repeats, is conserved in several limited-passage isolates but not in strain 17syn+.

scientific article published on March 1990

The herpes simplex virus 1 protein kinase U S 3 is required for protection from apoptosis induced by the virus ⬇️

scientific article published on July 22, 1997

The herpes simplex virus 1 protein kinase encoded by the US3 gene mediates posttranslational modification of the phosphoprotein encoded by the UL34 gene

scientific article published on November 1991

The herpes simplex virus UL20 protein compensates for the differential disruption of exocytosis of virions and viral membrane glycoproteins associated with fragmentation of the Golgi apparatus

scientific article published on November 1994

The herpes simplex virus Us11 open reading frame encodes a sequence-specific RNA-binding protein

scientific article published on July 1990

The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection

scientific article published on 6 February 2013

The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia

scientific article published on September 1996

The herpes simplex virus origins of DNA synthesis in the S component are each contained in a transcribed open reading frame.

scientific article published on November 1987

The herpesviruses--a biochemical definition of the group

scientific article

The heterogenous regions in herpes simplex virus 1 DNA

scientific article published on July 1, 1983

The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity.

scientific article published on 10 July 2001

The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13.

scientific article published on 13 February 2008

The nine ages of herpes simplex virus.

scientific article

The novel HSV-1 US5-1 RNA is transcribed off a domain encoding US5, US4, US3, US2 and alpha22.

scientific article

The nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAs

scientific article published on 09 October 2013

The null mutant of the U(L)31 gene of herpes simplex virus 1: construction and phenotype in infected cells ⬇️

scientific article published on November 1, 1997

The open reading frames UL3, UL4, UL10, and UL16 are dispensable for the replication of herpes simplex virus 1 in cell culture

scientific article published on February 1991

The order Herpesvirales

scientific article

The organization of the herpes simplex virus genomes ⬇️

scientific article published on January 1, 1979

The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene

scientific article

The phenotype in vitro and in infected cells of herpes simplex virus 1 alpha trans-inducing factor (VP16) carrying temperature-sensitive mutations introduced by substitution of cysteines

scientific article published on December 1995

The product of ORF O located within the domain of herpes simplex virus 1 genome transcribed during latent infection binds to and inhibits in vitro binding of infected cell protein 4 to its cognate DNA site

scientific article published on September 1997

The product of the UL31 gene of herpes simplex virus 1 is a nuclear phosphoprotein which partitions with the nuclear matrix ⬇️

scientific article published on November 1, 1993

The promoter and transcriptional unit of a novel herpes simplex virus 1 alpha gene are contained in, and encode a protein in frame with, the open reading frame of the alpha 22 gene

scientific article published in January 1996

The promoter, transcriptional unit, and coding sequence of herpes simplex virus 1 family 35 proteins are contained within and in frame with the UL26 open reading frame ⬇️

scientific article published on January 1, 1991

The proteins specified by herpes simplex virus. I. Time of synthesis, transfer into nuclei, and properties of proteins made in productively infected cells

scientific article published in December 1968

The range and distribution of murine central nervous system cells infected with the gamma(1)34.5- mutant of herpes simplex virus 1.

scientific article published in July 1997

The regulation of synthesis and properties of the protein product of open reading frame P of the herpes simplex virus 1 genome

scientific article published in June 1995

The regulations of gamma (structural) polypeptide synthesis in herpes simplex virus types 1 and 2 infected cells

scientific article published on 01 January 1978

The role of cdc2 in the expression of herpes simplex virus genes

scientific article published on September 2000

The role of the CoREST/REST repressor complex in herpes simplex virus 1 productive infection and in latency

scientific article

The sedimentation profiles of cytoplasmic polyribosomes in mammalian cells productively and abortively infected with herpes simplex virus

scientific article published in March 1968

The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase

scientific article

The structure and isomerization of herpes simplex virus genomes ⬇️

scientific article published on March 1, 1979

The structure of herpes simplex virus DNA and its application to molecular epidemiology ⬇️

scientific article published on January 1, 1980

The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component.

scientific article published on February 1986

The trans-activation of herpes simplex virus gene expression: comparison of two factors and their cis sites

scientific article

The transcription and state of herpes simplex virus DNA in productive infection and in human cervical cancer tissue

scientific article published in June 1973

The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem

scientific article published on 22 October 2008

The unique sequence of the herpes simplex virus 1 L component contains an additional translated open reading frame designated UL49.5 ⬇️

scientific article published on January 1, 1992

The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma

scientific article published in January 2002

The use of intertypic recombinants for analysis of gene organization in herpes simplex virus

scientific article published on 01 January 1978

The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1.

scientific article published on 9 January 2013

The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A

scientific article

The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes

scientific article published on 07 July 2009

The γ134.5 Protein of Herpes Simplex Virus 1 Has the Structural and Functional Attributes of a Protein Phosphatase 1 Regulatory Subunit and Is Present in a High Molecular Weight Complex with the Enzyme in Infected Cells ⬇️

scientific article published on August 14, 1998

Transcription initiation sites and nucleotide sequence of a herpes simplex virus 1 gene conserved in the Epstein-Barr virus genome and reported to affect the transport of viral glycoproteins

scientific article published on December 1986

Transcription of the derepressed open reading frame P of herpes simplex virus 1 precludes the expression of the antisense gamma(1)34.5 gene and may account for the attenuation of the mutant virus ⬇️

scientific article published on October 1, 1997

Translocation and colocalization of ICP4 and ICP0 in cells infected with herpes simplex virus 1 mutants lacking glycoprotein E, glycoprotein I, or the virion host shutoff product of the UL41 gene

scientific article

Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins ⬇️

scientific article published on January 1, 1998

Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage

scientific article published on 11 March 2015

Truncated forms of glycoprotein D of herpes simplex virus 1 capable of blocking apoptosis and of low-efficiency entry into cells form a heterodimer dependent on the presence of a cysteine located in the shared transmembrane domains

scientific article

Two overlapping transcription units which extend across the L-S junction of herpes simplex virus type 1.

scientific article published in May 1995

U S 3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosis ⬇️

scientific article published on August 15, 2011

U S 9, a stable lysine-less herpes simplex virus 1 protein, is ubiquitinated before packaging into virions and associates with proteasomes ⬇️

scientific article published on December 9, 1997

U(S)3 and U(S)3.5 protein kinases of herpes simplex virus 1 differ with respect to their functions in blocking apoptosis and in virion maturation and egress

scientific article

U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner.

scientific article

UL13 Protein Kinase of Herpes Simplex Virus 1 Complexes with Glycoprotein E and Mediates the Phosphorylation of the Viral Fc Receptor: Glycoproteins E and I ⬇️

scientific article published on February 1, 1998

UL27.5 is a novel gamma2 gene antisense to the herpes simplex virus 1 gene encoding glycoprotein B.

scientific article

UL34, the target of the herpes simplex virus U(S)3 protein kinase, is a membrane protein which in its unphosphorylated state associates with novel phosphoproteins ⬇️

scientific article published on July 1, 1992

Use of biotinylated plasmid DNA as a surrogate for HSV DNA to identify proteins that repress or activate viral gene expression

scientific article

Variability in the structural polypeptides of herpes simplex virus 1 strains: potential application in molecular epidemiology ⬇️

scientific article published on January 1, 1976

Variability of herpes simplex virus: isolation of two variants from simultaneous eruptions at different sites

scientific article published in February 1970

Variability, structural glycoproteins, and classification of herpes simplex viruses

scientific article published on 01 September 1970

Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1.

scientific article

Whither herpesviruses?

scientific article published on January 1990

Wild-type herpes simplex virus 1 blocks programmed cell death and release of cytochrome c but not the translocation of mitochondrial apoptosis-inducing factor to the nuclei of human embryonic lung fibroblasts

scientific article

[Biology of herpesviruses]

scientific article

cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor

scientific article

gamma 2-Thymidine kinase chimeras are identically transcribed but regulated a gamma 2 genes in herpes simplex virus genomes and as beta genes in cell genomes

scientific article published on March 1985

miR-H28 and miR-H29 expressed late in productive infection are exported and restrict HSV-1 replication and spread in recipient cells

scientific article published on February 2016

miRNAs Targeting ICP4 and Delivered to Susceptible Cells in Exosomes Block HSV-1 Replication in a Dose-Dependent Manner

scientific article published on 21 February 2018

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