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List of works by Sara E. Howden

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

scientific article published on 03 August 2016

ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.

scientific article published on 22 April 2016

Chemically defined conditions for human iPSC derivation and culture

scientific article

Chromatin-binding regions of EBNA1 protein facilitate the enhanced transfection of Epstein-Barr virus-based vectors.

scientific article published in August 2006

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis ⬇️

scientific article published on August 12, 2013

Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9 ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2018

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

scientific article published on September 2016

Gene targeting of human pluripotent stem cells by homologous recombination

scientific article published in January 2014

Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy.

scientific article

Integration of functional bacterial artificial chromosomes into human cord blood-derived multipotent stem cells.

scientific article

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation.

scientific article

Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment.

scientific article

Particle-mediated delivery of frataxin plasmid to a human sensory neuronal model of Friedreich's ataxia

scientific article published on 09 April 2020

Phosphorylation regulates human OCT4.

scientific article

Reporter-based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation

scientific article published on 11 March 2019

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

scientific article

Site-specific integration of bacterial artificial chromosomes into human cells.

scientific article published on January 2015

Site-specific, Rep-mediated integration of the intact beta-globin locus in the human erythroleukaemic cell line K562.

scientific article

The transient expression of mRNA coding for Rep protein from AAV facilitates targeted plasmid integration.

scientific article published in January 2008

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