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List of works by Randall S. Prather

A Genetic Porcine Model of Cancer

scientific article published on July 2015

A protein tyrosine phosphatase inhibitor, sodium orthovanadate, causes parthenogenetic activation of pig oocytes via an increase in protein tyrosine kinase activity

scientific article published in October 1999

A role for the Warburg effect in preimplantation embryo development: Metabolic modification to support rapid cell proliferation ⬇️

scientific article published on May 1, 2012

Aberrant DNA methylation in porcine in vitro-, parthenogenetic-, and somatic cell nuclear transfer-produced blastocysts.

scientific article published on February 2008

Acid peptidase activity released from in vitro produced porcine embryos: a candidate marker to predict developmental competence.

scientific article

Activation method does not alter abnormal placental gene expression and development in cloned pigs.

scientific article published on 5 October 2010

Activation of porcine oocytes via an exogenously introduced rat muscarinic M1 receptor

scientific article published in July 1997

Activation of porcine oocytes with calcium ionophore: effects of extracellular calcium

scientific article published in May 1999

Activation of ribosomal RNA genes in porcine embryos produced in vitro or by somatic cell nuclear transfer

scientific article published on 01 January 2007

Altered gene expression in cloned piglets.

scientific article published on January 2009

Altered gene expression profiles in the brain, kidney, and lung of one-month-old cloned pigs

scientific article

An intact sialoadhesin (Sn/SIGLEC1/CD169) is not required for attachment/internalization of the porcine reproductive and respiratory syndrome virus

scientific article published on 19 June 2013

Analysis of heterogeneous mitochondria distribution in somatic cell nuclear transfer porcine embryos.

scientific article published on October 2008

Apoptosis and in vitro development of preimplantation porcine embryos derived in vitro or by nuclear transfer

scientific article published on 16 April 2003

Apoptosis in parthenogenetic preimplantation porcine embryos

scientific article published on 6 February 2004

Applications of omics and nanotechnology to improve pig embryo production in vitro

scientific article published on 03 September 2019

Birth of piglets by in vitro fertilization of zona-free porcine oocytes.

scientific article published in November 2004

Birth of piglets from in vitro-produced, zona-intact porcine embryos vitrified in a closed system ⬇️

scientific article published on March 31, 2011

Calcium release and subsequent development induced by modification of sulfhydryl groups in porcine oocytes

scientific article published in June 1999

Cell Biology Symposium: Zinc finger nucleases to create custom-designed modifications in the swine (Sus scrofa) genome.

scientific article published on 28 October 2011

Changes in the structure of nuclei after transfer to oocytes.

scientific article

Characterization of DNA synthesis during the 2-cell stage and the production of tetraploid chimeric pig embryos

scientific article published in September 1996

Characterization of deoxyribonucleic acid synthesis and the transition from maternal to embryonic control in the 4-cell porcine embryo

scientific article published on 01 December 1992

Chemical simulation of hypoxia in donor cells improves development of somatic cell nuclear transfer-derived embryos and increases abundance of transcripts related to glycolysis

scientific article published on 17 June 2020

Cleavage stage porcine embryos may have differing developmental requirements for karyopherins alpha2 and alpha3.

scientific article published in March 2003

Cloned transgenic swine via in vitro production and cryopreservation

scientific article published on 3 May 2006

Cloning pigs as organ donors for humans

scientific article published in March 2004

Cloning. Pigs is pigs

scientific article published in September 2000

Complete activation of porcine oocytes induced by the sulfhydryl reagent, thimerosal

scientific article published in November 1997

Completion of the swine genome will simplify the production of swine as a large animal biomedical model

scientific article published on 15 November 2012

Construction of the nuclear matrix at the transition from maternal to zygotic control of development in the mouse: an immunocytochemical study

scientific article published on July 1, 1992

Creating genetically modified pigs by using nuclear transfer ⬇️

scientific article published on November 7, 2003

Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth

scientific article

Cytoplasmic modification of the nuclear lamina during pronuclear-like transformation of mouse blastomere nuclei

scientific article published in September 1991

Deciphering the mesodermal potency of porcine skin-derived progenitors (SKP) by microarray analysis.

scientific article

Degradation of maternal cdc25c during the maternal to zygotic transition is dependent upon embryonic transcription.

scientific article

Development and apoptosis of pre-implantation porcine nuclear transfer embryos activated with different combination of chemicals

scientific article published in September 2006

Development and expression of the green fluorescent protein in porcine embryos derived from nuclear transfer of transgenic granulosa-derived cells.

scientific article

Development of early porcine embryos in vitro and in vivo

scientific article published on 01 August 1998

Development of pig embryos reconstructed by microinjection of cultured fetal fibroblast cells into in vitro matured oocytes

scientific article published in June 1999

Developmental changes in the intracellular Ca2+ release mechanisms in porcine oocytes.

scientific article published in April 1997

Developmental competence of porcine parthenogenetic embryos relative to embryonic chromosomal abnormalities

scientific article published in January 2006

Developmental expression of 2489 gene clusters during pig embryogenesis: an expressed sequence tag project.

scientific article

Developmental regulation of an snRNP core protein epitope during pig embryogenesis and after nuclear transfer for cloning

scientific article published in October 1992

Discovery of putative oocyte quality markers by comparative ExacTag proteomics

scientific article

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

scientific article published on September 2008

Disruption of the Survival Motor Neuron (SMN) gene in pigs using ssDNA.

scientific article published on 25 February 2011

EST-based gene discovery in pig: virtual expression patterns and comparative mapping to human.

scientific article

Effect of elevated Ca(2+) concentration in fusion/activation medium on the fusion and development of porcine fetal fibroblast nuclear transfer embryos

scientific article

Effect of epidermal growth factor on preimplantation development and its receptor expression in porcine embryos

scientific article

Effect of myosin light chain kinase, protein kinase A, and protein kinase C inhibition on porcine oocyte activation.

scientific article

Effects of griseofulvin on in vitro porcine oocyte maturation and embryo development ⬇️

scientific article published on July 25, 2012

Effects of injecting calcium chloride into in vitro-matured porcine oocytes.

scientific article published in February 1996

Emerging applications of sperm, embryo and somatic cell cryopreservation in maintenance, relocation and rederivation of swine genetics

scientific article

Enhanced developmental potential of heat-shocked porcine parthenogenetic embryos is related to accelerated mitogen-activated protein kinase dephosphorylation.

scientific article published in January 2009

Evaluation of the acute phase response in cloned pigs following a lipopolysaccharide challenge.

scientific article published on 19 April 2005

Expression levels of growth-regulating imprinted genes in cloned piglets.

scientific article published in January 2007

Flow cytometric cell cycle analysis of cultured brown bear fibroblast cells.

scientific article published on 4 March 2008

Fragmentation and development of preimplantation porcine embryos derived by parthenogenetic activation and nuclear transfer.

scientific article published in June 2005

Functional analysis of activation of porcine oocytes by spermatozoa, calcium ionophore, and electrical pulse

scientific article published in November 1998

Gene editing as applied to prevention of reproductive porcine reproductive and respiratory syndrome

scientific article published on 8 April 2017

Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs ⬇️

scientific article published on January 1, 2011

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus

scientific article

Generation of an inbred miniature pig model of retinitis pigmentosa.

scientific article published on 31 January 2012

Generation of cloned transgenic pigs rich in omega-3 fatty acids

scientific article

Genetic modifications of pigs for medicine and agriculture.

scientific article

Genome-editing technologies to improve research, reproduction, and production in pigs.

scientific article published on 10 April 2017

Glutamine supplementation enhances development of in vitro-produced porcine embryos and increases leucine consumption from the medium

scientific article published on 01 November 2018

Glutaminolysis is involved in the activation of mTORC1 in in vitro-produced porcine embryos

scientific article published on 01 June 2021

Glycolysis in preimplantation development is partially controlled by the Warburg Effect.

scientific article published on 29 December 2011

Heat shock of porcine zygotes immediately after oocyte activation increases viability.

scientific article

Heat stress-induced apoptosis in porcine in vitro fertilized and parthenogenetic preimplantation-stage embryos

scientific article published in May 2007

High-throughput cryopreservation of in vivo-derived swine embryos

scientific article

Highly efficient and reliable chemically assisted enucleation method for handmade cloning in cattle

scientific article published in January 2005

Identification and characterization of the porcine (Sus scrofa) survival motor neuron (SMN1) gene: an animal model for therapeutic studies

scientific article published on August 2008

Identification and quantification of differentially represented transcripts in in vitro and in vivo derived preimplantation bovine embryos.

scientific article

Improved cryopreservation of in vitro produced bovine embryos using FGF2, LIF, and IGF1

scientific article published on 03 February 2021

Improvement of in vitro and early in utero porcine clone development after somatic donor cells are cultured under hypoxia.

scientific article

In vitro development of preimplantation porcine nuclear transfer embryos cultured in different media and gas atmospheres.

scientific article published in April 2004

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs

scientific article published on 8 May 2013

Knockout of maternal CD163 protects fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV).

scientific article published on 17 October 2017

Large-scale generation and analysis of expressed sequence tags from porcine ovary.

scientific article published on 11 August 2004

Leukemia inhibitory factor (LIF)-dependent, pluripotent stem cells established from inner cell mass of porcine embryos.

scientific article

Locus-specific DNA methylation reprogramming during early porcine embryogenesis.

scientific article published on 28 February 2013

Luteinization of porcine preovulatory follicles leads to systematic changes in follicular gene expression

scientific article published in July 2006

Maturation in Vitro of Pig Oocytes in Protein-Free Culture Media: Fertilization and Subsequent Embryo Development in Vitro1 ⬇️

scientific article published on May 1, 1998

Microtubule assembly after treatment of pig oocytes with taxol: correlation with chromosomes, gamma-tubulin, and MAP kinase.

scientific article published in December 2001

Mitochondrial distribution and microtubule organization in fertilized and cloned porcine embryos: implications for developmental potential.

scientific article published on 28 July 2006

Morphologic and histologic comparisons between in vivo and nuclear transfer derived porcine embryos.

scientific article published on August 2007

Morphologic comparison of ovulated and in vitro-matured porcine oocytes, with particular reference to polyspermy after in vitro fertilization

scientific article published in March 1998

Nuclear remodeling after SCNT: a contractor's nightmare.

scientific article published on May 2004

Optimization of square-wave electroporation for transfection of porcine fetal fibroblasts

scientific article

Osteopontin improves in vitro development of porcine embryos and decreases apoptosis.

scientific article published in February 2008

Osteopontin reduces polyspermy during in vitro fertilization of porcine oocytes

scientific article published on 26 July 2006

PAWP, a sperm-specific WW domain-binding protein, promotes meiotic resumption and pronuclear development during fertilization

scientific article

Parthenogenetic activation of pig eggs by exposure to protein kinase inhibitors

scientific article published on 01 January 1997

Parthenogenetic activation of pig oocytes with calcium ionophore and the block to sperm penetration after activation

scientific article published in June 1998

Parthenogenetic activation of porcine oocytes with guanosine-5'-O-(3'-thiotriphosphate).

scientific article

Parthenogenic activation of pig oocytes by protein kinase inhibition

scientific article published in August 1995

Parthenogenic development of in vitro-matured, in vivo-cultured porcine oocytes beyond blastocyst

scientific article published in February 1997

Pharmacologic treatment of donor cells induced to have a Warburg Effect-like metabolism does not alter embryonic development in vitro or survival during early gestation when used in somatic cell nuclear transfer in pigs.

scientific article published on 2 February 2018

Pharmacologic treatment with CPI-613 and PS48 decreases mitochondrial membrane potential and increases quantity of autolysosomes in porcine fibroblasts

scientific article published on 01 July 2019

Pig genomics for biomedicine ⬇️

scientific article published on 01 February 2013

Piglets produced from cloned blastocysts cultured in vitro with GM-CSF.

scientific article

Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth

scientific article

Porcine oocyte activation induced by a cytosolic sperm factor

scientific article published in November 2000

Porcine oocytes denuded before maturation can develop to the blastocyst stage if provided a cumulous cell-derived coculture system.

scientific article published on 9 April 2010

Porcine skin-derived progenitor (SKP) spheres and neurospheres: Distinct "stemness" identified by microarray analysis.

scientific article published on June 2010

Porcine skin-derived stem cells can serve as donor cells for nuclear transfer.

scientific article

Premature estrogen exposure alters endometrial gene expression to disrupt pregnancy in the pig

scientific article published on 19 July 2007

Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer

scientific article

Production of a transgenic piglet by a sperm injection technique in which no chemical or physical treatments were used for oocytes or sperm

scientific article published in May 2006

Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.

scientific article

Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs

scientific article

Production of endothelial nitric oxide synthase (eNOS) over-expressing piglets

scientific article published on 2 November 2006

Production of nuclear transfer-derived swine that express the enhanced green fluorescent protein.

scientific article published on November 2001

Production of piglets after cryopreservation of embryos using a centrifugation-based method for delipation without micromanipulation.

scientific article

Production of transgenic porcine blastocysts by nuclear transfer

scientific article published in June 2000

Pronuclear location before the first cell division determines ploidy of polyspermic pig embryos

scientific article published in November 1999

Rapid conceptus elongation in the pig: An interleukin 1 beta 2 and estrogen-regulated phenomenon.

scientific article published on 10 April 2017

Regulation of oocyte mitochondrial DNA copy number by follicular fluid, EGF, and neuregulin 1 during in vitro maturation affects embryo development in pigs ⬇️

scientific article published on May 22, 2012

Regulation of prohibitin expression during follicular development and atresia in the mammalian ovary

scientific journal article

Removal of hypotaurine from porcine embryo culture medium does not impair development of in vitro-fertilized or somatic cell nuclear transfer-derived embryos at low oxygen tension

scientific article published on 04 June 2020

Replacement of bovine serum albumin withN‐methyl‐D‐aspartic acid and homocysteine improves development, but not live birth ⬇️

scientific article published on March 29, 2012

Reproductive measurements in Sinclair and NIH miniature pigs: a retrospective analysis

scientific article published on 01 January 1997

Resistance to coronavirus infection in amino peptidase N-deficient pigs

scientific article published on 12 October 2018

Response of porcine oocytes to electrical and chemical activation during maturation in vitro

scientific article published in January 1991

Small RNA profile of the cumulus-oocyte complex and early embryos in the pig.

scientific article

Somatic cell nuclear transfer efficiency: how can it be improved through nuclear remodeling and reprogramming?

scientific article

Successful nonsurgical deep uterine embryo transfer in pigs

scientific article published on 01 January 2004

Targeted genetic modification: xenotransplantation and beyond.

scientific article published on January 2007

Telomere lengths in cloned transgenic pigs

scientific article published on 28 January 2004

The In Vivo Developmental Potential of Porcine Skin-Derived Progenitors and Neural Stem Cells ⬇️

scientific article published on May 17, 2012

The expression of nuclear lamin A and C epitopes is regulated by the developmental stage of the cytoplasm in mouse oocytes or embryos.

scientific article published in January 1991

The multi-potentiality of skin-derived stem cells in pigs.

scientific article

The porcine lung as a potential model for cystic fibrosis

scientific article published on 16 May 2008

The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs

scientific article

Timing of first embryonic cleavage is a positive indicator of the in vitro developmental potential of porcine embryos derived from in vitro fertilization, somatic cell nuclear transfer and parthenogenesis ⬇️

scientific article published on December 27, 2011

Transcriptional profiling by RNA-Seq of peri-attachment porcine embryos generated by a variety of assisted reproductive technologies.

scientific article published on 21 May 2013

Transcriptional profiling by deep sequencing identifies differences in mRNA transcript abundance in in vivo-derived versus in vitro-cultured porcine blastocyst stage embryos.

scientific article published on 28 July 2010

Transcriptional profiling of day 12 porcine embryonic disc and trophectoderm samples using ultra-deep sequencing technologies

scientific article published on 01 September 2010

Transcriptional profiling of pig embryogenesis by using a 15-K member unigene set specific for pig reproductive tissues and embryos

scientific article published on 9 February 2005

Transcriptional regulators TRIM28, SETDB1, and TP53 are aberrantly expressed in porcine embryos produced by in vitro fertilization in comparison to in vivo- and somatic-cell nuclear transfer-derived embryos

scientific article

Transgenic pig carrying green fluorescent proteasomes ⬇️

scientific article published on April 2, 2013

Transgenic pig expressing the enhanced green fluorescent protein produced by nuclear transfer using colchicine-treated fibroblasts as donor cells

scientific article published in July 2002

Transgenic pigs produced using in vitro matured oocytes infected with a retroviral vector

scientific article

Ubiquitin C-terminal hydrolase-activity is involved in sperm acrosomal function and anti-polyspermy defense during porcine fertilization.

scientific article published in August 2007

Vascular endothelium-specific overexpression of human catalase in cloned pigs ⬇️

scientific article published on December 18, 2010

Whatever happened to the "cell-block" during mammalian embryogenesis?

scientific article published on 01 May 2010

XenopusEgg Extract Treatment Reduced Global DNA Methylation of Donor Cells and Enhanced Somatic Cell Nuclear Transfer Embryo Development in Pigs ⬇️

scientific article published on April 1, 2012

gamma-Glutamyl transpeptidase of spermatozoa may decrease oocyte glutathione content at fertilization in pigs

scientific article published in December 1996

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