List of works - Johannes W. Dietrich

"Still crazy after all these years"--tuberculosis as an old disease with diverse facets in a thirty-five-year-old male patient.

scientific article

43-year-old woman with diabetes and postoperative circulatory collapse

scientific article

A novel minimal mathematical model of the hypothalamus-pituitary-thyroid axis validated for individualized clinical applications.

scientific article published on 28 January 2014

A novel simple disposition index (SPINA-DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis

scientific article published on 02 January 2024

Abnormal Cardiac Repolarization in Thyroid Diseases: Results of an Observational Study

scientific article published in 2021

Abnormal thyroid function is common in takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study

scientific article published on 12 November 2020

Absorption kinetics of levothyroxine is not altered by proton-pump inhibitor therapy

scientific article published in January 2006

Absorption, transport and bio-availability of iodothyronines

scientific article

Advances in applied homeostatic modelling of the relationship between thyrotropin and free thyroxine

scientific article published on 20 November 2017

Alterations in Titin Properties and Myocardial Fibrosis Correlate With Clinical Phenotypes in Hemodynamic Subgroups of Severe Aortic Stenosis

scientific article published on 25 June 2018

Association between left atrial low-voltage area, serum apoptosis, and fibrosis biomarkers and incidence of silent cerebral events after catheter ablation of atrial fibrillation.

scientific article

Association of left atrial low-voltage area and thromboembolic risk in patients with atrial fibrillation.

scientific article published on 25 July 2017

Bridge Technology with TSH Receptor Chimera for Sensitive Direct Detection of TSH Receptor Antibodies Causing Graves' Disease: Analytical and Clinical Evaluation

scientific article published on 16 June 2015

Calculated Parameters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research

scientific article

Characteristics predicting the efficacy of SGLT-2 inhibitors versus GLP-1 receptor agonists on major adverse cardiovascular events in type 2 diabetes mellitus: a meta-analysis study

scientific article published on 28 June 2023

Comment on "Levothyrox® New and Old Formulations: Are They Switchable for Millions of Patients?"

scientific article published on 31 March 2020

Compared to limb pain of other origin, ultrasonographic osteodensitometry reveals loss of bone density in complex regional pain syndrome

Computer Based Training in der Medizin

Edited book

Correlation between total atrial conduction time estimated via tissue Doppler imaging (PA-TDI Interval), structural atrial remodeling and new-onset of atrial fibrillation after cardiac surgery

scientific article published on 11 February 2013

CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops

scientific article published on 27 August 2024

Dankesworte zur Verleihung des Heinz-von-Foerster-Preises

scholarly article published on 13 December 2024

Das Refeeding-Syndrom – Eine Literaturübersicht

article published in 2014

Der Hypophysen-Schilddrüsen-Regelkreis

Monograph

Der Hypophysen-Schilddrüsen-Regelkreis

Doctoral thesis by Johannes W. Dietrich

Derivation of a multivariate reference range for pituitary thyrotropin and thyroid hormones: diagnostic efficiency compared with conventional single-reference method

scientific article published on 07 March 2016

Do thyroid-stimulating hormone, body weight, or body mass index serve as adequate markers to guide levothyroxine dose titration?

scientific article published in October 2013

Dual control of pituitary thyroid stimulating hormone secretion by thyroxine and triiodothyronine in athyreotic patients

scientific article published on June 2017

Editorial: "Homeostasis and Allostasis of Thyroid Function".

scientific article published on 5 June 2018

Editorial: Thyroid hormones and cardiac arrhythmia

scientific article published in 2022

Estimation of insulin sensitivity in diabetic Göttingen Minipigs

scientific article published in October 2016

Exchanging Catheters Over a Single Transseptal Sheath During Left Atrial Ablation is Associated with a Higher Risk for Silent Cerebral Events.

scientific article

Functional and Symptomatic Individuality in the Response to Levothyroxine Treatment

scientific article published on 26 September 2019

Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo

scientific article published on 10 July 2009

Hemodynamics of paradoxical severe aortic stenosis: insight from a pressure-volume loop analysis

scientific article published on 08 February 2019

Heterogenous biochemical expression of hormone activity in subclinical/overt hyperthyroidism and exogenous thyrotoxicosis

scientific article published on 08 February 2020

Higher incidence of esophageal lesions after ablation of atrial fibrillation related to the use of esophageal temperature probes

scientific article

Homeostatic Control of the Thyroid-Pituitary Axis: Perspectives for Diagnosis and Treatment

scientific article

Homeostatic equilibria between free thyroid hormones and pituitary thyrotropin are modulated by various influences including age, body mass index and treatment

scientific article (publication date: December 2014)

Hypothalamus-pituitary-thyroid feedback control: implications of mathematical modeling and consequences for thyrotropin (TSH) and free thyroxine (FT4) reference ranges

scientific article published in May 2014

Hypothyroidism – A Paradigm Shift

Book by Rudolf Hoermann and Johannes W. Dietrich

Impact of periprocedural anticoagulation strategy on the incidence of new-onset silent cerebral events after radiofrequency catheter ablation of atrial fibrillation.

scientific article

Impaired autonomic function and somatosensory disturbance in patients with treated autoimmune thyroiditis

Increased preoperative serum apoptosis marker fas ligand correlates with histopathology and new-onset of atrial fibrillation in patients after cardiac surgery.

scientific article published on 21 June 2013

Individualised requirements for optimum treatment of hypothyroidism: complex needs, limited options

scientific article published on 13 August 2019

Integration of Peripheral and Glandular Regulation of Triiodothyronine Production by Thyrotropin in Untreated and Thyroxine-Treated Subjects

scientific article

Is pituitary TSH an adequate measure of thyroid hormone-controlled homoeostasis during thyroxine treatment?

scientific article

Jenseits des TSH

Habilitation thesis by Johannes W. Dietrich

Lessons from Randomised Clinical Trials for Triiodothyronine Treatment of Hypothyroidism: Have They Achieved Their Objectives?

scientific article published on 16 July 2018

Letter by Dietrich et al Regarding Article, "Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes"

scientific article published on 01 April 2019

Letter to the Editor: Comment on "Reconciling the Log-Linear and Non-Linear Aspects of the TSH-Free T4 Relationship: Intra-Individual Analysis of a Large Population" by Rothacker K.M., et al

scientific article published on 01 April 2016

Mathematical Modeling of Thyroid Homeostasis: Implications for the Allan-Herndon-Dudley Syndrome

scientific article published on 24 January 2022

Mathematical Modeling of the Pituitary-Thyroid Feedback Loop: Role of a TSH-T3-Shunt and Sensitivity Analysis.

scientific article published on 21 March 2018

Mathematical modeling and simulation of thyroid homeostasis: Implications for the Allan-Herndon-Dudley syndrome

scientific article published in 2022

Minor perturbations of thyroid homeostasis and major cardiovascular endpoints–Physiological mechanisms and clinical evidence

scientific article published on 15 August 2022

Modelling of the thyroid hormone synthesis as a part of nonlinear reaction mechanism with feedback

scientific article published in June 2023

Mortality rates of severe COVID-19-related respiratory failure with and without extracorporeal membrane oxygenation in the Middle Ruhr Region of Germany

scientific article published on 29 March 2023

Multimedia in Health Sciences Education

Edited Book

Nonthyroidal Illness Syndrome in Cardiac Illness Involves Elevated Concentrations of 3,5-Diiodothyronine and Correlates with Atrial Remodeling

scientific article

Normal values for longitudinal function of the right ventricle in healthy women >70 years of age.

scientific article published on 23 April 2010

Of rats and men: thyroid homeostasis in rodents and human beings

scientific article

Optimal Hormone Replacement Therapy in Hypothyroidism - A Model Predictive Control Approach

scientific article published in 2022

P4-Endokrinologie – Kybernetische Perspektiven eines neuen Ansatzes ⬇️

scientific article published on 13 December 2024

Perspectives of (/memorandum for) systems thinking on COVID-19 pandemic and pathology

scientific article published in April 2023

Physiological states and functional relation between thyrotropin and free thyroxine in thyroid health and disease: in vivo and in silico data suggest a hierarchical model

scientific article

Principles of Endocrine Regulation: Reconciling Tensions Between Robustness in Performance and Adaptation to Change

scientific article published in 2022

Protection from diabetes development by single-chain antibody-mediated delivery of a NF-κB inhibitor specifically to β-cells in vivo

scientific article published on 26 April 2011

Recent Advances in Thyroid Hormone Regulation: Toward a New Paradigm for Optimal Diagnosis and Treatment.

scientific article published on 22 December 2017

Relational Stability in the Expression of Normality, Variation, and Control of Thyroid Function

scientific article

Relational Stability of Thyroid Hormones in Euthyroid Subjects and Patients with Autoimmune Thyroid Disease

scientific article

Respone to "Clinical parameters are more likely to be associated with thyroid hormone levels than with thyrotropin levels: A systematic review and meta-analysis"

scientific article published on 28 August 2020

Reverse Remodelling of the Atria After Treatment of Obstructive Sleep Apnoea with Continuous Positive Airway Pressure: Evidence from Electro-mechanical and Endocrine Markers.

scientific article published on 6 June 2015

Reverse atrial remodeling in patients who maintain sinus rhythm after electrical cardioversion: evidence derived from the measurement of total atrial conduction time assessed by PA-TDI interval

scientific article

SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function

scientific article published on 21 October 2022

Screening for Diabetes Mellitus in Patients with Hidradenitis Suppurativa-A Monocentric Study in Germany

scientific article published in April 2023

Second degree AV block and severely impaired contractility in cardiac myxedema: a case report.

scientific article published on 19 May 2015

Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.

scientific article

SimThyr

Simulation program for pituitary-thyroid feedback control

SimulaBeta

Continuous simulation program for insulin-glucose feedback control

Stand-alone mapping using different transluminal mapping catheters--an accurate and safe way to isolate all pulmonary veins with the cryoballoon?

scientific article

Symptomatic Relief is Related to Serum Free Triiodothyronine Concentrations during Follow-up in Levothyroxine-Treated Patients with Differentiated Thyroid Cancer.

scientific article published on 2 February 2018

Syndrome of inadequate antidiuretic hormone secretion in pulmonary tuberculosis - a therapeutic challenge ⬇️

scientific article published on February 18, 2013

THYROTROPIC FEEDBACK CONTROL: EVIDENCE FOR AN ADDITIONAL ULTRASHORT FEEDBACK LOOP FROM FRACTAL ANALYSIS

article

TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis

scientific article

TSH − Physiologie, Funktionsstörungen und Einflussfaktoren auf die Referenzwerte

scientific article published on 28 April 2014

The AQUA-FONTIS study: protocol of a multidisciplinary, cross-sectional and prospective longitudinal study for developing standardized diagnostics and classification of non-thyroidal illness syndrome

scientific article

The Quest for System-Theoretical Medicine in the COVID-19 Era

scientific article published in 2021

The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review

scientific article published on 3 December 2022

The Two Faces of Janus: Why Thyrotropin as a Cardiovascular Risk Factor May Be an Ambiguous Target

scientific article published on 26 October 2020

The parathyroid as a target for radiation damage

scientific article (publication date: 18 August 2011)

The proteomic signature of insulin-resistant human skeletal muscle reveals increased glycolytic and decreased mitochondrial enzymes.

scientific article

The role of functional thyroid capacity in pituitary thyroid feedback regulation

article published in 2018

The role of supporting and disruptive mechanisms of FT3 homeostasis in regulating the hypothalamic–pituitary–thyroid axis

scientific article published in January 2023

Thyroid Allostasis-Adaptive Responses of Thyrotropic Feedback Control to Conditions of Strain, Stress, and Developmental Programming.

scientific article

Thyroid Related Quality of Life in Elderly with Subclinical Hypothyroidism and Improvement on Levothyroxine is Distinct from that in Young Patients (TSAGE)

scientific article published on 10 September 2019

Thyroid examination in highly radiation-exposed workers after the Chernobyl accident.

scientific article published on 15 January 2009

Thyroid storm

scientific article

Thyroxine in goiter, H. pylori infection, and gastritis

scientific article published on 01 September 2006

Time for a reassessment of the treatment of hypothyroidism

scientific article published on 18 April 2019

Total atrial conduction time assessed by tissue doppler imaging (PA-TDI Interval) to predict early recurrence of persistent atrial fibrillation after successful electrical cardioversion.

scientific article published on 14 November 2013

Treatment options for subclinical hypothyroidism

scientific article published in September 2021

Treatment options for subclinical hypothyroidism

scientific article published on 4 August 2021

Triiodothyronine secretion in early thyroid failure: The adaptive response of central feedforward control

scientific article published on 01 February 2020

Understanding the restrictions in the prescription and use of potentially beneficial diabetes medications associated with low socio-economic status

scientific article published in March 2022

Usefulness of Serum Free Thyroxine Concentration to Predict Ventricular Arrhythmia Risk in Euthyroid Patients With Structural Heart Disease

scientific article published on 29 January 2020

Variation in the biochemical response to l-thyroxine therapy and relationship with peripheral thyroid hormone conversion efficiency

scientific article

We miss the opportunity: Pretreament of osteoporosis in a German trauma center

scientific article published in PLoS ONE

Who is afraid of non-normal data? Choosing between parametric and non-parametric tests: a response

scientific article published on 01 August 2020

Woman with type 1 diabetes mellitus and rapidly progressive edema

scientific article published on 23 April 2013

[Computer-assisted instruction in medicine: a multicenter evaluation study in 7 German language media resource centers]

scientific article published on 01 May 2000

[Thyroid storm]

scientific article published on 01 May 2019

List of works by Johannes W. Dietrich

"Still crazy after all these years"--tuberculosis as an old disease with diverse facets in a thirty-five-year-old male patient.

43-year-old woman with diabetes and postoperative circulatory collapse

A novel minimal mathematical model of the hypothalamus-pituitary-thyroid axis validated for individualized clinical applications.

A novel simple disposition index (SPINA-DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis

Abnormal Cardiac Repolarization in Thyroid Diseases: Results of an Observational Study

Abnormal thyroid function is common in takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study

Absorption kinetics of levothyroxine is not altered by proton-pump inhibitor therapy

Absorption, transport and bio-availability of iodothyronines

Advances in applied homeostatic modelling of the relationship between thyrotropin and free thyroxine

Alterations in Titin Properties and Myocardial Fibrosis Correlate With Clinical Phenotypes in Hemodynamic Subgroups of Severe Aortic Stenosis

Association between left atrial low-voltage area, serum apoptosis, and fibrosis biomarkers and incidence of silent cerebral events after catheter ablation of atrial fibrillation.

Association of left atrial low-voltage area and thromboembolic risk in patients with atrial fibrillation.

Bridge Technology with TSH Receptor Chimera for Sensitive Direct Detection of TSH Receptor Antibodies Causing Graves' Disease: Analytical and Clinical Evaluation

Calculated Parameters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research

Characteristics predicting the efficacy of SGLT-2 inhibitors versus GLP-1 receptor agonists on major adverse cardiovascular events in type 2 diabetes mellitus: a meta-analysis study

Comment on "Levothyrox® New and Old Formulations: Are They Switchable for Millions of Patients?"

Compared to limb pain of other origin, ultrasonographic osteodensitometry reveals loss of bone density in complex regional pain syndrome

Computer Based Training in der Medizin

Correlation between total atrial conduction time estimated via tissue Doppler imaging (PA-TDI Interval), structural atrial remodeling and new-onset of atrial fibrillation after cardiac surgery

CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops

Dankesworte zur Verleihung des Heinz-von-Foerster-Preises

Das Refeeding-Syndrom – Eine Literaturübersicht

Der Hypophysen-Schilddrüsen-Regelkreis

Der Hypophysen-Schilddrüsen-Regelkreis

Derivation of a multivariate reference range for pituitary thyrotropin and thyroid hormones: diagnostic efficiency compared with conventional single-reference method

Do thyroid-stimulating hormone, body weight, or body mass index serve as adequate markers to guide levothyroxine dose titration?

Dual control of pituitary thyroid stimulating hormone secretion by thyroxine and triiodothyronine in athyreotic patients

Editorial: "Homeostasis and Allostasis of Thyroid Function".

Editorial: Thyroid hormones and cardiac arrhythmia

Estimation of insulin sensitivity in diabetic Göttingen Minipigs

Exchanging Catheters Over a Single Transseptal Sheath During Left Atrial Ablation is Associated with a Higher Risk for Silent Cerebral Events.

Functional and Symptomatic Individuality in the Response to Levothyroxine Treatment

Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo

Hemodynamics of paradoxical severe aortic stenosis: insight from a pressure-volume loop analysis

Heterogenous biochemical expression of hormone activity in subclinical/overt hyperthyroidism and exogenous thyrotoxicosis

Higher incidence of esophageal lesions after ablation of atrial fibrillation related to the use of esophageal temperature probes

Homeostatic Control of the Thyroid-Pituitary Axis: Perspectives for Diagnosis and Treatment

Homeostatic equilibria between free thyroid hormones and pituitary thyrotropin are modulated by various influences including age, body mass index and treatment

Hypothalamus-pituitary-thyroid feedback control: implications of mathematical modeling and consequences for thyrotropin (TSH) and free thyroxine (FT4) reference ranges

Hypothyroidism – A Paradigm Shift

Impact of periprocedural anticoagulation strategy on the incidence of new-onset silent cerebral events after radiofrequency catheter ablation of atrial fibrillation.

Impaired autonomic function and somatosensory disturbance in patients with treated autoimmune thyroiditis

Increased preoperative serum apoptosis marker fas ligand correlates with histopathology and new-onset of atrial fibrillation in patients after cardiac surgery.

Individualised requirements for optimum treatment of hypothyroidism: complex needs, limited options

Integration of Peripheral and Glandular Regulation of Triiodothyronine Production by Thyrotropin in Untreated and Thyroxine-Treated Subjects

Is pituitary TSH an adequate measure of thyroid hormone-controlled homoeostasis during thyroxine treatment?

Jenseits des TSH

Lessons from Randomised Clinical Trials for Triiodothyronine Treatment of Hypothyroidism: Have They Achieved Their Objectives?

Letter by Dietrich et al Regarding Article, "Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes"

Letter to the Editor: Comment on "Reconciling the Log-Linear and Non-Linear Aspects of the TSH-Free T4 Relationship: Intra-Individual Analysis of a Large Population" by Rothacker K.M., et al

Mathematical Modeling of Thyroid Homeostasis: Implications for the Allan-Herndon-Dudley Syndrome

Mathematical Modeling of the Pituitary-Thyroid Feedback Loop: Role of a TSH-T3-Shunt and Sensitivity Analysis.

Mathematical modeling and simulation of thyroid homeostasis: Implications for the Allan-Herndon-Dudley syndrome

Minor perturbations of thyroid homeostasis and major cardiovascular endpoints–Physiological mechanisms and clinical evidence

Modelling of the thyroid hormone synthesis as a part of nonlinear reaction mechanism with feedback

Mortality rates of severe COVID-19-related respiratory failure with and without extracorporeal membrane oxygenation in the Middle Ruhr Region of Germany

Multimedia in Health Sciences Education

Nonthyroidal Illness Syndrome in Cardiac Illness Involves Elevated Concentrations of 3,5-Diiodothyronine and Correlates with Atrial Remodeling

Normal values for longitudinal function of the right ventricle in healthy women >70 years of age.

Of rats and men: thyroid homeostasis in rodents and human beings

Optimal Hormone Replacement Therapy in Hypothyroidism - A Model Predictive Control Approach

P4-Endokrinologie – Kybernetische Perspektiven eines neuen Ansatzes ⬇️

Perspectives of (/memorandum for) systems thinking on COVID-19 pandemic and pathology

Physiological states and functional relation between thyrotropin and free thyroxine in thyroid health and disease: in vivo and in silico data suggest a hierarchical model

Principles of Endocrine Regulation: Reconciling Tensions Between Robustness in Performance and Adaptation to Change

Protection from diabetes development by single-chain antibody-mediated delivery of a NF-κB inhibitor specifically to β-cells in vivo

Recent Advances in Thyroid Hormone Regulation: Toward a New Paradigm for Optimal Diagnosis and Treatment.

Relational Stability in the Expression of Normality, Variation, and Control of Thyroid Function

Relational Stability of Thyroid Hormones in Euthyroid Subjects and Patients with Autoimmune Thyroid Disease

Respone to "Clinical parameters are more likely to be associated with thyroid hormone levels than with thyrotropin levels: A systematic review and meta-analysis"

Reverse Remodelling of the Atria After Treatment of Obstructive Sleep Apnoea with Continuous Positive Airway Pressure: Evidence from Electro-mechanical and Endocrine Markers.

Reverse atrial remodeling in patients who maintain sinus rhythm after electrical cardioversion: evidence derived from the measurement of total atrial conduction time assessed by PA-TDI interval

SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function

Screening for Diabetes Mellitus in Patients with Hidradenitis Suppurativa-A Monocentric Study in Germany

Second degree AV block and severely impaired contractility in cardiac myxedema: a case report.

Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.

SimThyr

SimulaBeta

Stand-alone mapping using different transluminal mapping catheters--an accurate and safe way to isolate all pulmonary veins with the cryoballoon?